D-AKAP2:PKA RII:PDZK1 ternary complex structure: Insights from the nucleation of a polyvalent scaffold

Protein Science

Volumn 24, Issue 1, 2015, Pages 105-116

  Sarma, Ganapathy N ^a,b,e   Moody, Issa S ^a,b   Ilouz, Ronit ^c   Phan, Ryan H ^a,b   Sankaran, Banumathi ^d   Hall, Randy A ^e   Taylor, Susan S ^a,b  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b University of California San Diego   (United States)

^c LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^d EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e BRISTOL MYERS SQUIBB   (United States)

Author keywords

A kinase anchoring proteins; AKAP10; D AKAP2 specificity; PDZK1 crystal structure; PKA signaling

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE ANCHORING PROTEIN; CYCLIC AMP DEPENDENT PROTEIN KINASE REGULATORY SUBUNIT RII; DUAL SPECIFIC A KINASE ANCHORING PROTEIN 2; PDZ PROTEIN; PDZK1 PROTEIN; SIGNAL PEPTIDE; UNCLASSIFIED DRUG; AKAP10 PROTEIN, HUMAN; CARRIER PROTEIN; CYCLIC AMP DEPENDENT PROTEIN KINASE REGULATORY SUBUNIT IALPHA; PDZK1 PROTEIN, HUMAN; PRKAR1A PROTEIN, RAT;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENZYME BINDING; ENZYME STRUCTURE; PDZ DOMAIN; PRIORITY JOURNAL; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; AMINO ACID SEQUENCE; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; HUMAN; METABOLISM; MOLECULAR GENETICS; PROTEIN CONFORMATION; RAT; X RAY CRYSTALLOGRAPHY;

A KINASE ANCHOR PROTEINS; AMINO ACID SEQUENCE; ANIMALS; CARRIER PROTEINS; CRYSTALLOGRAPHY, X-RAY; CYCLIC AMP-DEPENDENT PROTEIN KINASE RIALPHA SUBUNIT; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PDZ DOMAINS; PROTEIN CONFORMATION; RATS;

EID: 84928950120     PISSN: 09618368     EISSN: 1469896X     Source Type: Journal    
DOI: 10.1002/pro.2593     Document Type: Article

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