Mechanisms underlying early rapid increases in creatinine in paraquat poisoning

PLoS ONE

Volumn 10, Issue 3, 2015, Pages

  Mohamed, Fahim ^a,b   Endre, Zoltan ^b   Jayamanne, Shaluka ^a   Pianta, Timothy ^b   Peake, Philip ^b   Palangasinghe, Chathura ^a   Chathuranga, Umesh ^a   Jayasekera, Kithsiri ^a   Wunnapuk, Klintean ^c   Shihana, Fathima ^a   Shahmy, Seyed ^a   Buckley, Nicholas ^a,b,d  

^a UNIVERSITY OF PERADENIYA   (Sri Lanka)

^b UNIVERSITY OF NEW SOUTH WALES   (Australia)

^c UNIVERSITY OF QUEENSLAND   (Australia)

^d UNIVERSITY OF SYDNEY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CREATININE; CYSTATIN C; PARAQUAT; BIOLOGICAL MARKER;

ACUTE KIDNEY FAILURE; ADULT; ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; CREATININE BLOOD LEVEL; CREATININE CLEARANCE; CREATININE URINE LEVEL; CYCLIZATION; FEMALE; GLOMERULUS FILTRATION RATE; HUMAN; KIDNEY DYSFUNCTION; KIDNEY TUBULE ACIDOSIS; MAJOR CLINICAL STUDY; MALE; OXIDATIVE STRESS; PARAQUAT POISONING; PROSPECTIVE STUDY; PROTEIN BLOOD LEVEL; PROTEIN SECRETION; URINALYSIS; URINE VOLUME; BLOOD; CHEMICALLY INDUCED; DRUG EFFECTS; KIDNEY; MIDDLE AGED; PATHOLOGY; URINE;

ACUTE KIDNEY INJURY; ADULT; BIOMARKERS; CREATININE; CYSTATIN C; FEMALE; GLOMERULAR FILTRATION RATE; HUMANS; KIDNEY; MALE; MIDDLE AGED; PARAQUAT;

EID: 84928905821     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0122357     Document Type: Article

References (58)

1. Lee WJ, Cha ES, Park ES, Kong KA, Yi JH, Son M. Deaths from pesticide poisoning in South Korea: trends over 10 years. Int Arch Occup Environ Health. 2009; 82: 365-371. doi: 10.1007/s00420-008-0343-z PMID: 18600341
2. Dawson AH, Eddleston M, Senarathna L, Mohamed F, Gawarammana I, Bowe SJ, et al. Acute human lethal toxicity of agricultural pesticides: a prospective cohort study. PLoS Med. 2010; 7: e1000357. doi: 10.1371/journal.pmed.1000357 PMID: 21048990
3. Roberts DM, Wilks MF, Roberts MS, Swaminathan R, Mohamed F, Dawson AH, et al. Changes in the concentrations of creatinine, cystatin C and NGAL in patients with acute paraquat self-poisoning. Toxicol Lett. 2011; 202: 69-74. doi: 10.1016/j.toxlet.2011.01.024 PMID: 21291964
4. Gawarammana IB, Buckley NA. Medical management of paraquat ingestion. Br J Clin Pharmacol. 2011; 72: 745-757. doi: 10.1111/j.1365-2125.2011.04026.x PMID: 21615775
5. Eddleston M, Wilks MF, Buckley NA. Prospects for treatment of paraquat-induced lung fibrosis with immunosuppressive drugs and the need for better prediction of outcome: a systematic review. QJM. 2003; 96: 809-824. PMID: 14566036
6. Gil HW, Yang JO, Lee EY, Hong SY. Clinical implication of urinary neutrophil gelatinase-associated lipocalin and kidney injury molecule-1 in patients with acute paraquat intoxication. Clin Toxicol (Phila). 2009; 47: 870-875. doi: 10.3109/15563650903306651 PMID: 19827907
7. Kim SJ, Gil HW, Yang JO, Lee EY, Hong SY. The clinical features of acute kidney injury in patients with acute paraquat intoxication. Nephrol Dial Transplant. 2009; 24: 1226-1232. doi: 10.1093/ndt/gfn615 PMID: 18987262
8. Lee EY, Hwang KY, Yang JO, Hong SY. Predictors of survival after acute paraquat poisoning. Toxicol Ind Health. 2002; 18: 201-206. PMID: 12974543
9. Molck AM, Friis C. The cytotoxic effect of paraquat to isolated renal proximal tubular segments from rabbits. Toxicology. 1997; 122: 123-132. PMID: 9274808
10. Roberts DM, Buckley NA. Pharmacokinetic considerations in clinical toxicology: clinical applications. Clin Pharmacokinet. 2007; 46: 897-939. PMID: 17922558
11. Bellomo R, Ronco C, Kellum JA, Mehta RL, Palevsky P. Acute renal failure-definition, outcome measures, animal models, fluid therapy and information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group. Crit Care. 2004; 8: R204-212. PMID: 15312219
12. Mehta RL, Kellum JA, Shah SV, Molitoris BA, Ronco C, Warnock DG, et al. Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury. Crit Care. 2007; 11: R31. PMID: 17331245
13. Endre ZH, Pickering JW, Walker RJ. Clearance and beyond: the complementary roles of GFR measurement and injury biomarkers in acute kidney injury (AKI). Am J Physiol Renal Physiol. 2011; 301: F697-707. doi: 10.1152/ajprenal.00448.2010 PMID: 21753074
14. Ragoucy-Sengler C, Pileire B. A biological index to predict patient outcome in paraquat poisoning. Hum Exp Toxicol. 1996; 15: 265-268. PMID: 8839218
15. Vaziri ND, Ness RL, Fairshter RD, Smith WR, Rosen SM. Nephrotoxicity of paraquat in man. Arch Intern Med. 1979; 139: 172-174. PMID: 434971
16. Aitken RG, Northall H, York GA. High serum concentrations of paraquat increase apparent creatinine concentrations. Ann Clin Biochem. 1994; 31: 198-199. PMID: 8060103
17. Price LA, Newman KJ, Clague AE, Wilson PR, Wenck DJ. Paraquat and diquat interference in the analysis of creatinine by the Jaffe reaction. Pathology. 1995; 27: 154-156. PMID: 7567143
18. Darby D, So J, Russell J, Monaghan PJ. Spuriously raised serum creatinine associated with an excipient present in an intravenous dexamethasone formulation. Ann Clin Biochem. 2012; 49: 292-294. doi: 10.1258/acb.2011.011114 PMID: 22349552
19. Wunnapuk K, Medley GA, Liu X, Grice JE, Jayasinghe S, Gawarammana I, et al. Simple and sensitive liquid chromatography-tandem mass spectrometry methods for quantification of paraquat in plasma and urine: application to experimental and clinical toxicological studies. J Chromatogr B Analyt Technol Biomed Life Sci. 2011; 879: 3047-3052. doi: 10.1016/j.jchromb.2011.09.008 PMID: 21956020
20. Pickering JW, Endre ZH. Back-calculating baseline creatinine with MDRD misclassifies acute kidney injury in the intensive care unit. Clin J Am Soc Nephrol. 2010; 5: 1165-1173. doi: 10.2215/CJN.08531109 PMID: 20498242
21. Inker LA, Schmid CH, Tighiouart H, Eckfeldt JH, Feldman HI, Greene T, et al. Estimating glomerular filtration rate from serum creatinine and cystatin C. N Engl J Med. 2012; 367: 20-29. doi: 10.1056/NEJMoa1114248 PMID: 22762315
22. Ralib AM, Pickering JW, Shaw GM, Devarajan P, Edelstein CL, Bonventre JV, et al. Test characteristics of urinary biomarkers depend on quantitation method in acute kidney injury. J Am Soc Nephrol. 2012; 23: 322-333. doi: 10.1681/ASN.2011040325 PMID: 22095948
23. Jelliffe R. Estimation of creatinine clearance in patients with unstable renal function, without a urine specimen. Am J Nephrol. 2002; 22: 320-324. PMID: 12169862
24. Rule AD, Bergstralh EJ, Slezak JM, Bergert J, Larson TS. Glomerular filtration rate estimated by cystatin C among different clinical presentations. Kidney Int. 2006; 69: 399-405. PMID: 16408133
25. Cockcroft DW, Gault MH. Prediction of creatinine clearance from serum creatinine. Nephron 1976; 16: 31-41. PMID: 1244564
26. Waikar SS, Bonventre JV. Creatinine kinetics and the definition of acute kidney injury. J Am Soc Nephrol. 2009; 20: 672-679. doi: 10.1681/ASN.2008070669 PMID: 19244578
27. Yashiro M, Ochiai M, Fujisawa N, Kadoya Y, Kamata T. Evaluation of estimated creatinine clearance before steady state in acute kidney injury by creatinine kinetics. Clin Exp Nephrol. 2012; 16: 570-579. doi: 10.1007/s10157-012-0602-x PMID: 22331371
28. Narayanan S, Appleton HD. Creatinine: a review. Clin Chem. 1980; 26: 1119-1126. PMID: 6156031
29. Webb DB, Davies CG. Paraquat poisoning and kidney function tests. Lancet. 1981; 1: 1424. PMID: 6113381
30. Tabata N, Morita M, Mimasaka S, Funayama M, Hagiwara T, Abe M. Paraquat myopathy: report on two suicide cases. Forensic Sci Int. 1999; 100: 117-126. PMID: 10356780
31. Panteghini M. Enzymatic assays for creatinine: time for action. Scand J Clin Lab Invest Suppl. 2008; 241: 84-88. doi: 10.1080/00365510802149978 PMID: 18569972
32. Dinis-Oliveira RJ, Duarte JA, Sanchez-Navarro A, Remiao F, Bastos ML, Carvalho F. Paraquat poisonings: mechanisms of lung toxicity, clinical features, and treatment. Crit Rev Toxicol. 2008; 38: 13-71. PMID: 18161502
33. Warren JD, Blumbergs PC, Thompson PD. Rhabdomyolysis: a review. Muscle Nerve. 2002; 25: 332-347. PMID: 11870710
34. Rose MS, Lock EA, Smith LL, Wyatt I. Paraquat accumulation: tissue and species specificity. Biochem Pharmacol. 1976; 25: 419-423. PMID: 820354
35. Visweswaran P, Guntupalli J. Rhabdomyolysis. Crit Care Clin. 1999; 15: 415-428, ix-x. PMID: 10331135
36. Sjostrom P, Tidman M, Jones I. The shorter T1/2 of cystatin C explains the earlier change of its serum level compared to serum creatinine. Clin Nephrol. 2004; 62: 241-242. PMID: 15481859
37. Chiou WL, Hsu FH. Pharmacokinetics of creatinine in man and its implications in the monitoring of renal function and in dosage regimen modifications in patients with renal insufficiency. J Clin Pharmacol. 1975; 15: 427-434. PMID: 1133219
38. Filler G, Bokenkamp A, Hofmann W, Le Bricon T, Martinez-Bru C, Grubb A. Cystatin C as a marker of GFR-history, indications, and future research. Clin Biochem. 2005: 38: 1-8. PMID: 15607309
39. Grubb AO. Cystatin C-properties and use as diagnostic marker. Adv Clin Chem. 2000; 35: 63-99. PMID: 11040958
40. Tenstad O, Roald AB, Grubb A, Aukland K. Renal handling of radiolabelled human cystatin C in the rat. Scand J Clin Lab Invest. 1996; 56: 409-414. PMID: 8869663
41. Uzun H, Ozmen Keles M, Ataman R, Aydin S, Kalender B, Uslu E, et al. Serum cystatin C level as a potentially good marker for impaired kidney function. Clin Biochem. 2005; 38: 792-798. PMID: 16005452
42. Hantson P, Weynand B, Doyle I, Bernand A, Hermans C. Pneumoproteins as markers of paraquat lung injury: a clinical case. J Forensic Leg Med. 2008; 15: 48-52. PMID: 17174135
43. Nejat M, Pickering JW, Walker RJ, Endre ZH. Rapid detection of acute kidney injury by plasma cystatin C in the intensive care unit. Nephrol Dial Transplant. 2010; 25: 3283-3289. doi: 10.1093/ndt/gfq176 PMID: 20350927
44. Knight EL, Verhave JC, Spiegelman D, Hillege HL, de Zeeuw D, Curhan GC, et al. Factors influencing serum cystatin C levels other than renal function and the impact on renal function measurement. Kidney Int. 2004; 65: 1416-1421. PMID: 15086483
45. Wiesli P, Schwegler B, Spinas GA, Schmid C. Serum cystatin C is sensitive to small changes in thyroid function. Clin Chim Acta. 2003; 338: 87-90. PMID: 14637271
46. Bagshaw SM, Gibney RT. Conventional markers of kidney function. Crit Care Med. 2008; 36: S152-158. doi: 10.1097/CCM.0b013e318168c613 PMID: 18382187
47. Uchino S. Creatinine. Curr Opin Crit Care. 2010; 16 (6):562-567. doi: 10.1097/MCC.0b013e32833ea7f3 PMID: 20736825
48. Wyss M, Kaddurah-Daouk R. Creatine and creatinine metabolism. Physiol Rev. 2000) 80: 1107-1213. PMID: 10893433
49. Doi K, Yuen PS, Eisner C, Hu X, Leelahavanichkul A, Schnermann J, et al. Reduced production of creatinine limits its use as marker of kidney injury in sepsis. J Am Soc Nephrol. 2009; 20: 1217-1221. doi: 10.1681/ASN.2008060617 PMID: 19389851
50. Ienaga K, Nakamura K, Fujisawa T, Fukunaga Y, Nihei H, Narita M, et al. Urinary excretion of creatol, an in vivo biomarker of hydroxyl radical, in patients with chronic renal failure. Ren Fail. 2007; 29: 279-283. PMID: 17497440
51. Matsumoto S, Hanai T, Matsuura T, Uemura H, Nishioka T, Akiyama T. Creatol, an oxidative product of creatinine in kidney transplant patients, as a useful determinant of renal function: a preliminary study. Transplant Proc. 2006; 38: 2009-2011. PMID: 16979981
52. Ienaga K, Yokozawa T. Creatinine and HMH (5-hydroxy-1-methylhydantoin, NZ-419) as intrinsic hydroxyl radical scavengers. Drug Discov Ther. 2011; 5: 162-175. PMID: 22466296
53. Borsook H, Dubnoff JW. The hydrolysis of phosphocreatine and the origin of urinary creatinine. J Biol Chem. 1947; 168: 493-510. PMID: 20238607
54. Wright SH, Wunz TM. Paraquat2+/H+ exchange in isolated renal brush-border membrane vesicles. Biochim Biophys Acta. 1995; 1240: 18-24. PMID: 7495843
55. Chen Y, Zhang S, Sorani M, Giacomini KM. Transport of paraquat by human organic cation transporters and multidrug and toxic compound extrusion family. J Pharmacol Exp Ther. 2007; 322: 695-700. PMID: 17495125
56. Jonker JW, Wagenaar E, Van Eijl S, Schinkel AH. Deficiency in the organic cation transporters 1 and 2 (Oct1/Oct2 [Slc22a1/Slc22a2]) in mice abolishes renal secretion of organic cations. Mol Cell Biol. 2003; 23: 7902-7908. PMID: 14560032
57. Urakami Y, Kimura N, Okuda M, Masuda S, Katsura T, Inui K. Transcellular transport of creatinine in renal tubular epithelial cell line LLC-PK1. Drug Metab Pharmacokinet. 2005; 20: 200-205. PMID: 15988122
58. Urakami Y, Kimura N, Okuda M, Inui K. Creatinine transport by basolateral organic cation transporter hOCT2 in the human kidney. Pharm Res. 2004; 21: 976-981. PMID: 15212162