Typhoid Fever in Young Children in Bangladesh: Clinical Findings, Antibiotic Susceptibility Pattern and Immune Responses

PLoS Neglected Tropical Diseases

Volumn 9, Issue 4, 2015, Pages

  Khanam, Farhana ^a   Sayeed, Md Abu ^a   Choudhury, Feroza Kaneez ^a   Sheikh, Alaullah ^a,b   Ahmed, Dilruba ^a   Goswami, Doli ^a   Hossain, Md Lokman ^a   Brooks, Abdullah ^a   Calderwood, Stephen B ^c,d   Charles, Richelle C ^c,d   Cravioto, Alejandro ^e   Ryan, Edward T ^c,d,f   Qadri, Firdausi ^a  

^a INTERNATIONAL CENTRE FOR DIARRHOEAL DISEASE RESEARCH   (Bangladesh)

^b WASHINGTON UNIVERSITY   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

^e DF ^*  (Mexico)

^f HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AZITHROMYCIN; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; NALIDIXIC ACID; ANTIINFECTIVE AGENT;

ABDOMINAL PAIN; ABDOMINAL TENDERNESS; ADOLESCENT; ADULT; ANTIBIOTIC SENSITIVITY; ANTIBODY RESPONSE; ARTICLE; BANGLADESH; BLOOD CULTURE; CHILD; CLINICAL FEATURE; COATED TONGUE; CONVALESCENCE; DIARRHEA; DISK DIFFUSION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FEVER; HEADACHE; HEPATOMEGALY; HUMAN; IMMUNE RESPONSE; LOSS OF APPETITE; LYMPHOCYTE PROLIFERATION; MAJOR CLINICAL STUDY; MALE; MULTIDRUG RESISTANCE; MYALGIA; NONHUMAN; RASH; SALMONELLA ENTERICA; SPLENOMEGALY; T LYMPHOCYTE; TYPHOID FEVER; BACTEREMIA; CELL PROLIFERATION; DRUG EFFECTS; IMMUNOLOGY; MIDDLE AGED; PHYSIOLOGY; PRESCHOOL CHILD; SALMONELLA ENTERICA SEROVAR TYPHI; SPECIES DIFFERENCE; YOUNG ADULT;

ADOLESCENT; ADULT; ANTI-BACTERIAL AGENTS; BACTEREMIA; BANGLADESH; CELL PROLIFERATION; CHILD; CHILD, PRESCHOOL; FEMALE; HUMANS; MALE; MIDDLE AGED; SALMONELLA TYPHI; SPECIES SPECIFICITY; T-LYMPHOCYTES; TYPHOID FEVER; YOUNG ADULT;

EID: 84928902587     PISSN: 19352727     EISSN: 19352735     Source Type: Journal    
DOI: 10.1371/journal.pntd.0003619     Document Type: Article

References (24)

1. Crump JA, Luby SP, Mintz ED, (2004) The global burden of typhoid fever. Bull World Health Organ 82: 346–353. 15298225
2. Sinha A, Sazawal S, Kumar R, Sood S, Reddaiah VP, et al. (1999) Typhoid fever in children aged less than 5 years. Lancet 354: 734–737. 10475185
3. Saha SK, Ruhulamin M, Hanif M, Islam M, Khan WA, (1996) Interpretation of the Widal test in the diagnosis of typhoid fever in Bangladeshi children. Ann Trop Paediatr 16: 75–78. 8787370
4. Saha SK, Baqui AH, Hanif M, Darmstadt GL, Ruhulamin M, et al. (2001) Typhoid fever in Bangladesh: implications for vaccination policy. Pediatr Infect Dis J 20: 521–524. 11368111
5. Brooks WA, Hossain A, Goswami D, Nahar K, Alam K, et al. (2005) Bacteremic typhoid fever in children in an urban slum, Bangladesh. Emerg Infect Dis 11: 326–329. 15752457
6. Naheed A, Ram PK, Brooks WA, Hossain MA, Parsons MB, et al. (2010) Burden of typhoid and paratyphoid fever in a densely populated urban community, Dhaka, Bangladesh. Int J Infect Dis 14 Suppl 3: e93–99. doi: 10.1016/j.ijid.2009.11.023 20236850
7. Ferreccio C, Levine MM, Manterola A, Rodriguez G, Rivara I, et al. (1984) Benign bacteremia caused by Salmonella typhi and paratyphi in children younger than 2 years. J Pediatr 104: 899–901. 6427437
8. Mulligan TO, (1971) Typhoid fever in young children. Br Med J 4: 665–667. 5134566
9. Koul PB, Murali MV, Sharma PP, Ghai OP, Ramchandran VG, et al. (1991) Multi drug resistant Salmonella typhi infection: clinical profile and therapy. Indian Pediatr 28: 357–361. 1752652
10. Sheikh A, Bhuiyan MS, Khanam F, Chowdhury F, Saha A, et al. (2009) Salmonella enterica serovar Typhi-specific immunoglobulin A antibody responses in plasma and antibody in lymphocyte supernatant specimens in Bangladeshi patients with suspected typhoid fever. Clin Vaccine Immunol 16: 1587–1594. doi: 10.1128/CVI.00311-09 19741090
11. Khanam F (2013) TPTest. PNTD.
12. Clinical and Laboratory Standards Institute. 2010. Performance Standards for Antimicrobial Susceptibility Testing; Twentieth Informational Supplement. CLSI M100-S20. Clinical and Laboratory Standards Institute. Wayne, PA.
13. al. ABe (1989) Quality control parameters and the interpretive criteria for the in vitro susceptibility tests with the macrolide azithromycin. European J clin Microbiol and Infect Dis 8: 544–549. 2548865
14. Qadri F, Ryan ET, Faruque AS, Ahmed F, Khan AI, et al. (2003) Antigen-specific immunoglobulin A antibodies secreted from circulating B cells are an effective marker for recent local immune responses in patients with cholera: comparison to antibody-secreting cell responses and other immunological markers. Infect Immun 71: 4808–4814. 12874365
15. Bhuiyan TR, Qadri F, Saha A, Svennerholm AM, (2009) Infection by Helicobacter pylori in Bangladeshi children from birth to two years: relation to blood group, nutritional status, and seasonality. Pediatr Infect Dis J 28: 79–85. doi: 10.1097/INF.0b013e31818a5d9d 19116602
16. Wenneras C, Qadri F, Bardhan PK, Sack RB, Svennerholm AM, (1999) Intestinal immune responses in patients infected with enterotoxigenic Escherichia coli and in vaccinees. Infect Immun 67: 6234–6241. 10569732
17. Sheikh A, Khanam F, Sayeed MA, Rahman T, Pacek M, et al. (2011) Interferon-gamma and proliferation responses to Salmonella enterica Serotype Typhi proteins in patients with S. Typhi Bacteremia in Dhaka, Bangladesh. PLoS Negl Trop Dis 5: e1193. doi: 10.1371/journal.pntd.0001193 21666798
18. Kilhamn J, Lundin SB, Brevinge H, Svennerholm AM, Jertborn M, (2003) T- and B-cell immune responses of patients who had undergone colectomies to oral administration of Salmonella enterica serovar Typhi Ty21a vaccine. Clin Diagn Lab Immunol 10: 426–430. 12738643
19. Lundin BS, Johansson C, Svennerholm AM, (2002) Oral immunization with a Salmonella enterica serovar typhi vaccine induces specific circulating mucosa-homing CD4(+) and CD8(+) T cells in humans. Infect Immun 70: 5622–5627. 12228290
20. Wahid R, Salerno-Goncalves R, Tacket CO, Levine MM, Sztein MB, (2007) Cell-mediated immune responses in humans after immunization with one or two doses of oral live attenuated typhoid vaccine CVD 909. Vaccine 25: 1416–1425. 17182155
21. Arora RK, Gupta A, Joshi NM, Kataria VK, Lall P, et al. (1992) Multidrug resistant typhoid fever: study of an outbreak in Calcutta. Indian Pediatr 29: 61–66. 1601498
22. Dutta TK, Beeresha Ghotekar LH, (2001) Atypical manifestations of typhoid fever. J Postgrad Med 47: 248–251. 11832640
23. Chisti MJ, Bardhan PK, Huq S, Khan WA, Khan AM, et al. (2009) High-dose intravenous dexamethasone in the management of diarrheal patients with enteric fever and encephalopathy. Southeast Asian J Trop Med Public Health 40: 1065–1073. 19842390
24. Lutterloh E, Likaka A, Sejvar J, Manda R, Naiene J, et al. (2012) Multidrug-resistant typhoid fever with neurologic findings on the Malawi-Mozambique border. Clin Infect Dis 54: 1100–1106. doi: 10.1093/cid/cis012 22357702