Long-term once-daily tiotropium Respimat® is well tolerated and maintains efficacy over 52 weeks in patients with symptomatic asthma in Japan: A randomised, placebo-controlled study

PLoS ONE

Volumn 10, Issue 4, 2015, Pages

  Ohta, Ken ^a   Ichinose, Masakazu ^b   Tohda, Yuji ^c   Engel, Michael ^d   Moroni Zentgraf, Petra ^d   Kunimitsu, Satoko ^e   Sakamoto, Wataru ^e   Adachi, Mitsuru ^f  

^a TOKYO NATIONAL HOSPITAL   (Japan)

^b TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c KINKI UNIVERSITY   (Japan)

^d BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

^e NIPPON BOEHRINGER INGELHEIM CO LTD   (Japan)

^f INTERNATIONAL UNIVERSITY OF HEALTH AND WELFARE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BUDESONIDE; PLACEBO; SALBUTAMOL; TIOTROPIUM BROMIDE; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; BRONCHODILATING AGENT; CHOLINERGIC RECEPTOR BLOCKING AGENT; CORTICOSTEROID;

ADULT; AGED; ALLERGIC CONJUNCTIVITIS; ALLERGIC RHINITIS; ARTICLE; ASTHMA; BACKACHE; BRONCHITIS; CONSTIPATION; CONTROLLED STUDY; CYSTITIS; DIARRHEA; DISEASE SEVERITY; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; DYSPHONIA; FEMALE; FORCED EXPIRATORY VOLUME; GASTRITIS; GASTROENTERITIS; GASTROESOPHAGEAL REFLUX; HEADACHE; HUMAN; HYPERTENSION; INFLUENZA; JAPAN; LONG TERM CARE; LUNG FUNCTION; MAJOR CLINICAL STUDY; MALE; PEAK EXPIRATORY FLOW; PHARYNGITIS; PHASE 3 CLINICAL TRIAL; QUESTIONNAIRE; RANDOMIZED CONTROLLED TRIAL; RHINOPHARYNGITIS; SPRAIN; SYMPTOM; TREATMENT DURATION; UPPER RESPIRATORY TRACT INFECTION; VASCULAR DISEASE; ADOLESCENT; CLINICAL TRIAL; DRUG ADMINISTRATION; INHALATIONAL DRUG ADMINISTRATION; MIDDLE AGED; NEBULIZER; TIME FACTOR; TREATMENT OUTCOME; YOUNG ADULT;

ADMINISTRATION, INHALATION; ADOLESCENT; ADRENAL CORTEX HORMONES; ADRENERGIC BETA-2 RECEPTOR AGONISTS; ADULT; AGED; ASTHMA; BRONCHODILATOR AGENTS; CHOLINERGIC ANTAGONISTS; DOUBLE-BLIND METHOD; DRUG ADMINISTRATION SCHEDULE; FEMALE; FORCED EXPIRATORY VOLUME; HUMANS; JAPAN; MALE; MIDDLE AGED; NEBULIZERS AND VAPORIZERS; PEAK EXPIRATORY FLOW RATE; SURVEYS AND QUESTIONNAIRES; TIME FACTORS; TIOTROPIUM BROMIDE; TREATMENT OUTCOME; YOUNG ADULT;

EID: 84928887136     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0124109     Document Type: Article

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