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Volumn 51, Issue 4, 2015, Pages 185-192

Indications for Active Case Searches and Intravenous Alpha-1 Antitrypsin Treatment for Patients With Alpha-1 Antitrypsin Deficiency Chronic Pulmonary Obstructive Disease: An Update;Actualización sobre indicaciones de búsqueda activa de casos y tratamiento con alfa-1 antitripsina por vía intravenosa en pacientes con enfermedad pulmonar obstructiva crónica asociada a déficit de alfa-1 antitripsina

Author keywords

Alpha 1 antitrypsin deficiency; Diagnoses; Spanish Registry of Patients with alpha 1 antitrypsin deficiency; Treatment

Indexed keywords

ALPHA 1 ANTITRYPSIN; PLACEBO;

EID: 84928882668     PISSN: 03002896     EISSN: 15792129     Source Type: Journal    
DOI: 10.1016/j.arbr.2014.12.006     Document Type: Article
Times cited : (63)

References (111)
  • 1
    • 0141706635 scopus 로고    scopus 로고
    • American Thoracic Society/European Respiratory Society Statement: Standards for the diagnosis and management of individuals with alpha1-antitrypsin deficiency
    • American Thoracic Society/European Respiratory Society Statement: Standards for the diagnosis and management of individuals with alpha1-antitrypsin deficiency. Am J Respir Crit Care Med 2003, 168:818-900.
    • (2003) Am J Respir Crit Care Med , vol.168 , pp. 818-900
  • 3
    • 33846346558 scopus 로고    scopus 로고
    • Normativa SEPAR: diagnóstico y tratamiento del déficit de alfa-1-antitripsina
    • Comité del Registro Nacional de Pacientes con Déficit de Alfa-1-Antitripsina
    • Vidal R., Blanco I., Casas F., Jardí R., Miravitlles M. Normativa SEPAR: diagnóstico y tratamiento del déficit de alfa-1-antitripsina. Arch Bronconeumol 2006, 42:645-659. Comité del Registro Nacional de Pacientes con Déficit de Alfa-1-Antitripsina.
    • (2006) Arch Bronconeumol , vol.42 , pp. 645-659
    • Vidal, R.1    Blanco, I.2    Casas, F.3    Jardí, R.4    Miravitlles, M.5
  • 4
    • 67649407825 scopus 로고    scopus 로고
    • Exploring the role of CT densitometry: A randomised study of augmentation therapy in alpha1-antitrypsin deficiency
    • Dirksen A., Piitulainen E., Parr D.G., Deng C., Wencker M., Shaker S.B., et al. Exploring the role of CT densitometry: A randomised study of augmentation therapy in alpha1-antitrypsin deficiency. Eur Respir J 2009, 33:1345-1353.
    • (2009) Eur Respir J , vol.33 , pp. 1345-1353
    • Dirksen, A.1    Piitulainen, E.2    Parr, D.G.3    Deng, C.4    Wencker, M.5    Shaker, S.B.6
  • 5
    • 77957273246 scopus 로고    scopus 로고
    • Therapeutic efficacy of -1 antitrypsin augmentation therapy on the loss of lung tissue: An integrated analysis of 2 randomised clinical trials using computed tomography densitometry
    • Stockley R.A., Parr D.G., Piitulainen E., Stolk J., Stoel B.C., Dirksen A. Therapeutic efficacy of -1 antitrypsin augmentation therapy on the loss of lung tissue: An integrated analysis of 2 randomised clinical trials using computed tomography densitometry. Respir Res 2010, 11:136-144.
    • (2010) Respir Res , vol.11 , pp. 136-144
    • Stockley, R.A.1    Parr, D.G.2    Piitulainen, E.3    Stolk, J.4    Stoel, B.C.5    Dirksen, A.6
  • 7
    • 35448959593 scopus 로고    scopus 로고
    • Prevalence of alpha-1 antitrypsin deficiency in poorly controlled asthma -results from the ALA-ACRC low-dose theophylline trial
    • Eden E., Holbrook J.T., Brantly M.L., Turino G.M., Wise R.A. Prevalence of alpha-1 antitrypsin deficiency in poorly controlled asthma -results from the ALA-ACRC low-dose theophylline trial. J Asthma 2007, 44:605-608.
    • (2007) J Asthma , vol.44 , pp. 605-608
    • Eden, E.1    Holbrook, J.T.2    Brantly, M.L.3    Turino, G.M.4    Wise, R.A.5
  • 9
    • 42149188192 scopus 로고    scopus 로고
    • Screening and familial testing of patients for alpha 1-antitrypsin deficiency
    • Hogarth D.K., Rachelefsky G. Screening and familial testing of patients for alpha 1-antitrypsin deficiency. Chest 2008, 133:981-988.
    • (2008) Chest , vol.133 , pp. 981-988
    • Hogarth, D.K.1    Rachelefsky, G.2
  • 10
    • 77955487511 scopus 로고    scopus 로고
    • Intravenous alpha-1 antitrypsin augmentation therapy for treating patients with alpha-1 antitrypsin deficiency and lung disease
    • Gøtzsche P.C., Johansen H.K. Intravenous alpha-1 antitrypsin augmentation therapy for treating patients with alpha-1 antitrypsin deficiency and lung disease. Cochrane Database Syst Rev 2010, CD007851. (7).
    • (2010) Cochrane Database Syst Rev , Issue.7 , pp. CD007851
    • Gøtzsche, P.C.1    Johansen, H.K.2
  • 11
    • 77957659757 scopus 로고    scopus 로고
    • Intravenous alpha-1 antitrypsin augmentation therapy: Systematic review
    • Gøtzsche P.C., Johansen H.K. Intravenous alpha-1 antitrypsin augmentation therapy: Systematic review. Dan Med Bull 2010, 57:A4175.
    • (2010) Dan Med Bull , vol.57 , pp. A4175
    • Gøtzsche, P.C.1    Johansen, H.K.2
  • 12
    • 70350450961 scopus 로고    scopus 로고
    • Augmentation therapy for alpha1 antitrypsin deficiency: A meta-analysis
    • Chapman K.R., Stockley R.A., Dawkins C., Wilkes M.M., Navickis R.J. Augmentation therapy for alpha1 antitrypsin deficiency: A meta-analysis. COPD 2009, 6:177-184.
    • (2009) COPD , vol.6 , pp. 177-184
    • Chapman, K.R.1    Stockley, R.A.2    Dawkins, C.3    Wilkes, M.M.4    Navickis, R.J.5
  • 13
    • 84861316814 scopus 로고    scopus 로고
    • Alpha-1 antitrypsin deficiency targeted testing and augmentation therapy: A Canadian Thoracic Society clinical practice guideline
    • Canadian Thoracic Society COPD Clinical Assembly Alpha-1 Antitrypsin Deficiency Expert Working Group
    • Marciniuk D.D., Hernandez P., Balter M., Bourbeau J., Chapman K.R., Ford G.T., et al. Alpha-1 antitrypsin deficiency targeted testing and augmentation therapy: A Canadian Thoracic Society clinical practice guideline. Can Respir J 2012, 19:109-116. Canadian Thoracic Society COPD Clinical Assembly Alpha-1 Antitrypsin Deficiency Expert Working Group.
    • (2012) Can Respir J , vol.19 , pp. 109-116
    • Marciniuk, D.D.1    Hernandez, P.2    Balter, M.3    Bourbeau, J.4    Chapman, K.R.5    Ford, G.T.6
  • 14
    • 0019787989 scopus 로고
    • Replacement therapy of alpha 1-antitrypsin deficiency. Reversal of protease-antiprotease imbalance within the alveolar structures of PiZ subjects
    • Gadek J.E., Klein H.G., Holland P.V., Crystal R.G. Replacement therapy of alpha 1-antitrypsin deficiency. Reversal of protease-antiprotease imbalance within the alveolar structures of PiZ subjects. J Clin Invest 1981, 68:1158-1165.
    • (1981) J Clin Invest , vol.68 , pp. 1158-1165
    • Gadek, J.E.1    Klein, H.G.2    Holland, P.V.3    Crystal, R.G.4
  • 15
    • 84944363276 scopus 로고
    • From the NIH: Intravenous replacement therapy for patients with severe alpha 1-antitrypsin deficiency
    • From the NIH: Intravenous replacement therapy for patients with severe alpha 1-antitrypsin deficiency. JAMA. 1982, 248:1693.
    • (1982) JAMA. , vol.248 , pp. 1693
  • 16
    • 0020680610 scopus 로고
    • Experience with replacement therapy in the destructive lung disease associated with severe alpha-1-antitrypsin deficiency
    • Gadek J.E., Crystal R.G. Experience with replacement therapy in the destructive lung disease associated with severe alpha-1-antitrypsin deficiency. Am Rev Respir Dis 1983, 127:S45-S46.
    • (1983) Am Rev Respir Dis , vol.127 , pp. S45-S46
    • Gadek, J.E.1    Crystal, R.G.2
  • 17
    • 0020663341 scopus 로고
    • Alpha 1 antitrypsin deficiency: clinical and physiological features in heterozygotes of Pi type SZ. A survey by the British Thoracic Association
    • Hutchison D.C., Tobin M.J., Cook P.J. Alpha 1 antitrypsin deficiency: clinical and physiological features in heterozygotes of Pi type SZ. A survey by the British Thoracic Association. Br J Dis Chest 1983, 77:28-34.
    • (1983) Br J Dis Chest , vol.77 , pp. 28-34
    • Hutchison, D.C.1    Tobin, M.J.2    Cook, P.J.3
  • 19
    • 0023784904 scopus 로고
    • Biochemical efficacy and safety of monthly augmentation therapy for alpha 1-antitrypsin deficiency
    • Hubbard R.C., Sellers S., Czerski D., Stephens L., Crystal R.G. Biochemical efficacy and safety of monthly augmentation therapy for alpha 1-antitrypsin deficiency. JAMA 1988, 260:1259-1264.
    • (1988) JAMA , vol.260 , pp. 1259-1264
    • Hubbard, R.C.1    Sellers, S.2    Czerski, D.3    Stephens, L.4    Crystal, R.G.5
  • 20
    • 0023925114 scopus 로고
    • Replacement therapy for alpha-1-protease inhibitor deficiency in PiZ subjects with chronic obstructive lung disease
    • Schmidt E.W., Rasche B., Ulmer W.T., Konietzko N., Becker M., Fallise J.P., et al. Replacement therapy for alpha-1-protease inhibitor deficiency in PiZ subjects with chronic obstructive lung disease. Am J Med 1988, 84:63-69.
    • (1988) Am J Med , vol.84 , pp. 63-69
    • Schmidt, E.W.1    Rasche, B.2    Ulmer, W.T.3    Konietzko, N.4    Becker, M.5    Fallise, J.P.6
  • 21
    • 0024477218 scopus 로고
    • Replacement therapy in alpha 1-antitrypsin deficiency
    • Eriksson S. Replacement therapy in alpha 1-antitrypsin deficiency. J Intern Med 1989, 225:69-72.
    • (1989) J Intern Med , vol.225 , pp. 69-72
    • Eriksson, S.1
  • 22
    • 0025241020 scopus 로고
    • Aspects of treatment in alpha 1-antitrypsin deficiency: Insights derived from a Swedish PiZZ series
    • Eriksson S., Wu M.C. Aspects of treatment in alpha 1-antitrypsin deficiency: Insights derived from a Swedish PiZZ series. Eur Respir J Suppl 1990, 9:39s-43s.
    • (1990) Eur Respir J Suppl , vol.9 , pp. 39s-43s
    • Eriksson, S.1    Wu, M.C.2
  • 24
    • 0025890293 scopus 로고
    • Cost-effectiveness of alpha-1 antitrypsin replacement therapy in treatment of congenital chronic obstructive pulmonary disease
    • Hay J.W., Robin E.D. Cost-effectiveness of alpha-1 antitrypsin replacement therapy in treatment of congenital chronic obstructive pulmonary disease. Am J Public Health 1991, 81:427-433.
    • (1991) Am J Public Health , vol.81 , pp. 427-433
    • Hay, J.W.1    Robin, E.D.2
  • 25
    • 0026926198 scopus 로고
    • Alpha 1-antitrypsin-deficiency-related emphysema
    • Barker A.F. Alpha 1-antitrypsin-deficiency-related emphysema. J Am Board Fam Pract 1992, 5:489-493.
    • (1992) J Am Board Fam Pract , vol.5 , pp. 489-493
    • Barker, A.F.1
  • 26
    • 0026510873 scopus 로고
    • Current status of alpha-1-antitrypsin replacement therapy: Recommendations for the management of patients with severe hereditary deficiency. Ad Hoc Committee on Alpha-1-Antitrypsin Replacement Therapy of the Standards Committee, Canadian Thoracic Society
    • Ad Hoc Committee on alpha-1 antitrypsin replacement therapy of the Standards Committee, Canadian Thoracic Society
    • Current status of alpha-1-antitrypsin replacement therapy: Recommendations for the management of patients with severe hereditary deficiency. Ad Hoc Committee on Alpha-1-Antitrypsin Replacement Therapy of the Standards Committee, Canadian Thoracic Society. CMAJ 1992, 146:841-844. Ad Hoc Committee on alpha-1 antitrypsin replacement therapy of the Standards Committee, Canadian Thoracic Society.
    • (1992) CMAJ , vol.146 , pp. 841-844
  • 27
    • 0026939035 scopus 로고
    • Alpha-1-antitrypsin replacement therapy -an early Australian experience
    • Burdon J., Cook L., Holmes P., Janus E., Watts S. Alpha-1-antitrypsin replacement therapy -an early Australian experience. Aust N Z J Med 1992, 22:498-499.
    • (1992) Aust N Z J Med , vol.22 , pp. 498-499
    • Burdon, J.1    Cook, L.2    Holmes, P.3    Janus, E.4    Watts, S.5
  • 28
    • 0028070026 scopus 로고
    • Failure to achieve adequate serum levels with monthly replacement therapy in alpha 1-antitrypsin deficiency
    • Cammarata S.K., Stone C.L., Carey J.L., Eichenhorn M.S. Failure to achieve adequate serum levels with monthly replacement therapy in alpha 1-antitrypsin deficiency. Chest 1994, 106:651-652.
    • (1994) Chest , vol.106 , pp. 651-652
    • Cammarata, S.K.1    Stone, C.L.2    Carey, J.L.3    Eichenhorn, M.S.4
  • 30
    • 0029155644 scopus 로고
    • Clinical trials needed for alpha 1-antitrypsin replacement therapy
    • Bhagat R., Swystun V.A., Cockcroft D.W. Clinical trials needed for alpha 1-antitrypsin replacement therapy. Chest 1995, 108:586-587.
    • (1995) Chest , vol.108 , pp. 586-587
    • Bhagat, R.1    Swystun, V.A.2    Cockcroft, D.W.3
  • 31
    • 0029349461 scopus 로고
    • The evolution of the replacement treatment of emphysema due to alpha 1-antitrypsin deficiency
    • Manresa F. The evolution of the replacement treatment of emphysema due to alpha 1-antitrypsin deficiency. Arch Bronconeumol 1995, 31:371-372.
    • (1995) Arch Bronconeumol , vol.31 , pp. 371-372
    • Manresa, F.1
  • 32
    • 0030466338 scopus 로고    scopus 로고
    • Pathogenesis of hereditary emphysema and replacement therapy for alpha 1-antitrypsin deficiency. Insight into the more common forms of emphysema
    • Gadek J.E., Pacht E.R. Pathogenesis of hereditary emphysema and replacement therapy for alpha 1-antitrypsin deficiency. Insight into the more common forms of emphysema. Chest 1996, 110:248s-250s.
    • (1996) Chest , vol.110 , pp. 248s-250s
    • Gadek, J.E.1    Pacht, E.R.2
  • 34
    • 0030446288 scopus 로고    scopus 로고
    • Clinical features of individuals with PI*SZ phenotype of alpha 1-antitrypsin deficiency
    • Alpha 1-Antitrypsin Deficiency Registry Study Group
    • Turino G.M., Barker A.F., Brantly M.L., Cohen A.B., Connelly R.P., Crystal R.G., et al. Clinical features of individuals with PI*SZ phenotype of alpha 1-antitrypsin deficiency. Am J Respir Crit Care Med 1996, 154:1718-1725. Alpha 1-Antitrypsin Deficiency Registry Study Group.
    • (1996) Am J Respir Crit Care Med , vol.154 , pp. 1718-1725
    • Turino, G.M.1    Barker, A.F.2    Brantly, M.L.3    Cohen, A.B.4    Connelly, R.P.5    Crystal, R.G.6
  • 35
    • 2642680855 scopus 로고    scopus 로고
    • Alpha 1-antitrypsin deficiency: Memorandum from a WHO meeting
    • Alpha 1-antitrypsin deficiency: Memorandum from a WHO meeting. Bull World Health Organ 1997, 75:397-415.
    • (1997) Bull World Health Organ , vol.75 , pp. 397-415
  • 36
    • 0030663669 scopus 로고    scopus 로고
    • Alpha-1-antitrypsin replacement therapy: Will its efficacy ever be proved
    • Hutchison D.C., Hughes M.D. Alpha-1-antitrypsin replacement therapy: Will its efficacy ever be proved. Eur Respir J 1997, 10:2191-2193.
    • (1997) Eur Respir J , vol.10 , pp. 2191-2193
    • Hutchison, D.C.1    Hughes, M.D.2
  • 37
    • 0031242842 scopus 로고    scopus 로고
    • Does alpha1-antitrypsin augmentation therapy slow the annual decline in FEV1 in patients with severe hereditary alpha1-antitrypsin deficiency? Wissenschaftliche Arbeitsgemeinschaft zur Therapie von Lungenerkrankungen (WATL) alpha1-AT study group
    • Seersholm N., Wencker M., Banik N., Viskum K., Dirksen A., Kok-Jensen A., et al. Does alpha1-antitrypsin augmentation therapy slow the annual decline in FEV1 in patients with severe hereditary alpha1-antitrypsin deficiency? Wissenschaftliche Arbeitsgemeinschaft zur Therapie von Lungenerkrankungen (WATL) alpha1-AT study group. Eur Respir J 1997, 10:2260-2263.
    • (1997) Eur Respir J , vol.10 , pp. 2260-2263
    • Seersholm, N.1    Wencker, M.2    Banik, N.3    Viskum, K.4    Dirksen, A.5    Kok-Jensen, A.6
  • 38
    • 0032013907 scopus 로고    scopus 로고
    • ¿ Deberíamos administrar tratamiento sustitutivo a los pacientes con déficit de alfa-1 antitripsina?
    • Miravitlles M. ¿ Deberíamos administrar tratamiento sustitutivo a los pacientes con déficit de alfa-1 antitripsina?. Arch Bronconeumol 1998, 34:109-111.
    • (1998) Arch Bronconeumol , vol.34 , pp. 109-111
    • Miravitlles, M.1
  • 39
    • 0031756969 scopus 로고    scopus 로고
    • Usefulness of a national registry of alpha-1-antitrypsin deficiency. The Spanish experience
    • Miravitlles M., Vidal R., Barros-Tizón J.C., Bustamante A., España P.P., Casas F., et al. Usefulness of a national registry of alpha-1-antitrypsin deficiency. The Spanish experience. Respir Med 1998, 92:1181-1187.
    • (1998) Respir Med , vol.92 , pp. 1181-1187
    • Miravitlles, M.1    Vidal, R.2    Barros-Tizón, J.C.3    Bustamante, A.4    España, P.P.5    Casas, F.6
  • 40
    • 0032110436 scopus 로고    scopus 로고
    • Survival and FEV1 decline in individuals with severe deficiency of alpha1-antitrypsin
    • The Alpha-1-Antitrypsin Deficiency Registry Study Group
    • Survival and FEV1 decline in individuals with severe deficiency of alpha1-antitrypsin. Am J Respir Crit Care Med 1998, 158:49-59. The Alpha-1-Antitrypsin Deficiency Registry Study Group.
    • (1998) Am J Respir Crit Care Med , vol.158 , pp. 49-59
  • 41
    • 0031884479 scopus 로고    scopus 로고
    • Long-term treatment of alpha1-antitrypsin deficiency-related pulmonary emphysema with human alpha1-antitrypsin. Wissenschaftliche Arbeitsgemeinschaft zur Therapie von Lungenerkrankungen(WATL)-alpha1-AT-study group
    • Wencker M., Banik N., Buhl R., Seidel R., Konietzko N. Long-term treatment of alpha1-antitrypsin deficiency-related pulmonary emphysema with human alpha1-antitrypsin. Wissenschaftliche Arbeitsgemeinschaft zur Therapie von Lungenerkrankungen(WATL)-alpha1-AT-study group. Eur Respir J 1998, 11:428-433.
    • (1998) Eur Respir J , vol.11 , pp. 428-433
    • Wencker, M.1    Banik, N.2    Buhl, R.3    Seidel, R.4    Konietzko, N.5
  • 42
    • 84880726176 scopus 로고    scopus 로고
    • Alpha-1 antitrypsin augmentation therapy and biomarkers of elastin degradation
    • Ma S., Lin Y.Y., He J., Rouhani F.N., Brantly M., Turino G.M. Alpha-1 antitrypsin augmentation therapy and biomarkers of elastin degradation. COPD 2013, 10:473-481.
    • (2013) COPD , vol.10 , pp. 473-481
    • Ma, S.1    Lin, Y.Y.2    He, J.3    Rouhani, F.N.4    Brantly, M.5    Turino, G.M.6
  • 43
    • 0038166283 scopus 로고    scopus 로고
    • Alpha 1-protease inhibitor deficiency. Diagnosis, follow-up and therapy options
    • Köhnlein T., Klein H., Welte T. Alpha 1-protease inhibitor deficiency. Diagnosis, follow-up and therapy options. Med Klin (Munich) 1999, 94:371-376.
    • (1999) Med Klin (Munich) , vol.94 , pp. 371-376
    • Köhnlein, T.1    Klein, H.2    Welte, T.3
  • 44
    • 0033796561 scopus 로고    scopus 로고
    • Formation and current results of a patient-organized registry for alpha(1)-antitrypsin deficiency
    • Stoller J.K., Brantly M., Fleming L.E., Bean J.A., Walsh J. Formation and current results of a patient-organized registry for alpha(1)-antitrypsin deficiency. Chest 2000, 118:843-848.
    • (2000) Chest , vol.118 , pp. 843-848
    • Stoller, J.K.1    Brantly, M.2    Fleming, L.E.3    Bean, J.A.4    Walsh, J.5
  • 45
    • 0034066328 scopus 로고    scopus 로고
    • Feasibility of a clinical trial of augmentation therapy for alpha(1)-antitrypsin deficiency. The Alpha 1-Antitrypsin Deficiency Registry Study Group
    • Schluchter M.D., Stoller J.K., Barker A.F., Buist A.S., Crystal R.G., Donohue J.F., et al. Feasibility of a clinical trial of augmentation therapy for alpha(1)-antitrypsin deficiency. The Alpha 1-Antitrypsin Deficiency Registry Study Group. Am J Respir Crit Care Med 2000, 161:796-801.
    • (2000) Am J Respir Crit Care Med , vol.161 , pp. 796-801
    • Schluchter, M.D.1    Stoller, J.K.2    Barker, A.F.3    Buist, A.S.4    Crystal, R.G.5    Donohue, J.F.6
  • 46
    • 0033739182 scopus 로고    scopus 로고
    • Augmentation therapy reduces frequency of lung infections in antitrypsin deficiency: A new hypothesis with supporting data
    • Lieberman J. Augmentation therapy reduces frequency of lung infections in antitrypsin deficiency: A new hypothesis with supporting data. Chest 2000, 118:1480-1485.
    • (2000) Chest , vol.118 , pp. 1480-1485
    • Lieberman, J.1
  • 47
    • 0034017941 scopus 로고    scopus 로고
    • Should health-care systems pay for replacement therapy in patients with alpha(1)-antitrypsin deficiency? A critical review and cost-effectiveness analysis
    • Alkins S.A., O'Malley P. Should health-care systems pay for replacement therapy in patients with alpha(1)-antitrypsin deficiency? A critical review and cost-effectiveness analysis. Chest 2000, 117:875-880.
    • (2000) Chest , vol.117 , pp. 875-880
    • Alkins, S.A.1    O'Malley, P.2
  • 48
    • 0033995116 scopus 로고    scopus 로고
    • Distribution of alpha(1)-antitrypsin alleles in patients with bronchiectasis
    • Cuvelier A., Muir J.F., Hellot M.F., Benhamou D., Martin J.P., Bénichou J., et al. Distribution of alpha(1)-antitrypsin alleles in patients with bronchiectasis. Chest 2000, 117:415-419.
    • (2000) Chest , vol.117 , pp. 415-419
    • Cuvelier, A.1    Muir, J.F.2    Hellot, M.F.3    Benhamou, D.4    Martin, J.P.5    Bénichou, J.6
  • 49
    • 0033979879 scopus 로고    scopus 로고
    • Risk of hospital admission for obstructive pulmonary disease in alpha(1)-antitrypsin heterozygotes of phenotype PiMZ
    • Seersholm N., Wilcke J.T., Kok-Jensen A., Dirksen A. Risk of hospital admission for obstructive pulmonary disease in alpha(1)-antitrypsin heterozygotes of phenotype PiMZ. Am J Respir Crit Care Med 2000, 161:81-84.
    • (2000) Am J Respir Crit Care Med , vol.161 , pp. 81-84
    • Seersholm, N.1    Wilcke, J.T.2    Kok-Jensen, A.3    Dirksen, A.4
  • 50
    • 0034743745 scopus 로고    scopus 로고
    • Alpha1-antitrypsin deficiency: A position statement of the Canadian Thoracic Society
    • Standards Committee of the Canadian Thoracic Society
    • Abboud R.T., Ford G.T., Chapman K.R. Alpha1-antitrypsin deficiency: A position statement of the Canadian Thoracic Society. Can Respir J 2001, 8:81-88. Standards Committee of the Canadian Thoracic Society.
    • (2001) Can Respir J , vol.8 , pp. 81-88
    • Abboud, R.T.1    Ford, G.T.2    Chapman, K.R.3
  • 51
    • 0034889702 scopus 로고    scopus 로고
    • High-resolution computed tomography scanning in alpha1-antitrypsin deficiency: Relationship to lung function and health status
    • Dowson L.J., Guest P.J., Hill S.L., Holder R.L., Stockley R.A. High-resolution computed tomography scanning in alpha1-antitrypsin deficiency: Relationship to lung function and health status. Eur Respir J 2001, 17:1097-1104.
    • (2001) Eur Respir J , vol.17 , pp. 1097-1104
    • Dowson, L.J.1    Guest, P.J.2    Hill, S.L.3    Holder, R.L.4    Stockley, R.A.5
  • 52
    • 0036447470 scopus 로고    scopus 로고
    • A preliminary assessment of alpha-1 antitrypsin S and Z deficiency allele frequencies in common variable immunodeficiency patients with and without bronchiectasis
    • Sansom M.E., Ferry B.L., Sherrell Z.P., Chapel H.M. A preliminary assessment of alpha-1 antitrypsin S and Z deficiency allele frequencies in common variable immunodeficiency patients with and without bronchiectasis. Clin Exp Immunol 2002, 130:489-494.
    • (2002) Clin Exp Immunol , vol.130 , pp. 489-494
    • Sansom, M.E.1    Ferry, B.L.2    Sherrell, Z.P.3    Chapel, H.M.4
  • 53
    • 0035095548 scopus 로고    scopus 로고
    • Wissenschaftliche Arbeitsgemeinschaft zur Therapie von Lungenerkrankungen. Longitudinal follow-up of patients with alpha (1)-protease inhibitor deficiency before and during therapy with IV alpha(1)-protease inhibitor
    • Wencker M., Fuhrmann B., Banik N., Konietzko N. Wissenschaftliche Arbeitsgemeinschaft zur Therapie von Lungenerkrankungen. Longitudinal follow-up of patients with alpha (1)-protease inhibitor deficiency before and during therapy with IV alpha(1)-protease inhibitor. Chest 2001, 119:737-744.
    • (2001) Chest , vol.119 , pp. 737-744
    • Wencker, M.1    Fuhrmann, B.2    Banik, N.3    Konietzko, N.4
  • 55
    • 0036606880 scopus 로고    scopus 로고
    • The effect of augmentation therapy on bronchial inflammation in alpha1-antitrypsin deficiency
    • Stockley R.A., Bayley D.L., Unsal I., Dowson L.J. The effect of augmentation therapy on bronchial inflammation in alpha1-antitrypsin deficiency. Am J Respir Crit Care Med 2002, 165:1494-1498.
    • (2002) Am J Respir Crit Care Med , vol.165 , pp. 1494-1498
    • Stockley, R.A.1    Bayley, D.L.2    Unsal, I.3    Dowson, L.J.4
  • 56
    • 0036488898 scopus 로고    scopus 로고
    • Influence of deficient alpha1-anti-trypsin phenotypes on clinical characteristics and severity of asthma in adults
    • Miravitlles M., Vilà S., Torrella M., Balcells E., Rodríguez-Frías F., de la Roza C., et al. Influence of deficient alpha1-anti-trypsin phenotypes on clinical characteristics and severity of asthma in adults. Respir Med 2002, 96:186-192.
    • (2002) Respir Med , vol.96 , pp. 186-192
    • Miravitlles, M.1    Vilà, S.2    Torrella, M.3    Balcells, E.4    Rodríguez-Frías, F.5    de la Roza, C.6
  • 57
    • 0038216603 scopus 로고    scopus 로고
    • Augmentation therapy with alpha1-antitrypsin: Patterns of use and adverse events
    • Stoller J.K., Fallat R., Schluchter M.D., O'Brien R.G., Connor J.T., Gross N., et al. Augmentation therapy with alpha1-antitrypsin: Patterns of use and adverse events. Chest 2003, 123:1425-1434.
    • (2003) Chest , vol.123 , pp. 1425-1434
    • Stoller, J.K.1    Fallat, R.2    Schluchter, M.D.3    O'Brien, R.G.4    Connor, J.T.5    Gross, N.6
  • 58
    • 0347291902 scopus 로고    scopus 로고
    • Predictors of mortality in alpha1-antitrypsin deficiency
    • Dawkins P.A., Dowson L.J., Guest P.J., Stockley R.A. Predictors of mortality in alpha1-antitrypsin deficiency. Thorax 2003, 58:1020-1026.
    • (2003) Thorax , vol.58 , pp. 1020-1026
    • Dawkins, P.A.1    Dowson, L.J.2    Guest, P.J.3    Stockley, R.A.4
  • 59
    • 0141558799 scopus 로고    scopus 로고
    • Major components of the direct medical costs of alpha1-antitrypsin deficiency
    • Mullins C.D., Wang J., Stoller J.K. Major components of the direct medical costs of alpha1-antitrypsin deficiency. Chest 2003, 124:826-831.
    • (2003) Chest , vol.124 , pp. 826-831
    • Mullins, C.D.1    Wang, J.2    Stoller, J.K.3
  • 60
    • 0037952677 scopus 로고    scopus 로고
    • Cost-effectiveness analysis of augmentation therapy for severe alpha1-antitrypsin deficiency
    • Gildea T.R., Shermock K.M., Singer M.E., Stoller J.K. Cost-effectiveness analysis of augmentation therapy for severe alpha1-antitrypsin deficiency. Am J Respir Crit Care Med 2003, 167:1387-1392.
    • (2003) Am J Respir Crit Care Med , vol.167 , pp. 1387-1392
    • Gildea, T.R.1    Shermock, K.M.2    Singer, M.E.3    Stoller, J.K.4
  • 61
    • 6344238675 scopus 로고    scopus 로고
    • Chronic obstructive pulmonary disease in a1-antitrypsin PI MZ heterozygotes: A meta-analysis
    • Hersh C.P., Dahl M., Ly N.P., Berkey C.S., Nordestgaard B.G., Silverman E.K. Chronic obstructive pulmonary disease in a1-antitrypsin PI MZ heterozygotes: A meta-analysis. Thorax 2004, 59:843-849.
    • (2004) Thorax , vol.59 , pp. 843-849
    • Hersh, C.P.1    Dahl, M.2    Ly, N.P.3    Berkey, C.S.4    Nordestgaard, B.G.5    Silverman, E.K.6
  • 62
    • 18144430936 scopus 로고    scopus 로고
    • A review of alpha-1 antitrypsin deficiency
    • Ranes J., Stoller J.K. A review of alpha-1 antitrypsin deficiency. Semin Respir Crit Care Med 2005, 26:154-166.
    • (2005) Semin Respir Crit Care Med , vol.26 , pp. 154-166
    • Ranes, J.1    Stoller, J.K.2
  • 63
    • 14944385198 scopus 로고    scopus 로고
    • Emphysema in alpha1-antitrypsin deficiency: Does replacement therapy affect outcome?
    • Abboud R.T., Ford G.T., Chapman K.R. Emphysema in alpha1-antitrypsin deficiency: Does replacement therapy affect outcome?. Treat Respir Med 2005, 4:1-8.
    • (2005) Treat Respir Med , vol.4 , pp. 1-8
    • Abboud, R.T.1    Ford, G.T.2    Chapman, K.R.3
  • 64
    • 33745076743 scopus 로고    scopus 로고
    • Cost-effectiveness of population screening for alpha-1 antitrypsin deficiency: A decision analysis
    • Shermock K.M., Gildea T.R., Singer M., Stoller J.K. Cost-effectiveness of population screening for alpha-1 antitrypsin deficiency: A decision analysis. COPD 2005, 2:411-418.
    • (2005) COPD , vol.2 , pp. 411-418
    • Shermock, K.M.1    Gildea, T.R.2    Singer, M.3    Stoller, J.K.4
  • 65
    • 33745032125 scopus 로고    scopus 로고
    • Multi-center study: The biochemical efficacy, safety and tolerability of a new alpha1-proteinase inhibitor, Zemaira
    • Stocks J.M., Brantly M., Pollock D., Barker A., Kueppers F., Strange C., et al. Multi-center study: The biochemical efficacy, safety and tolerability of a new alpha1-proteinase inhibitor, Zemaira. COPD 2006, 3:17-23.
    • (2006) COPD , vol.3 , pp. 17-23
    • Stocks, J.M.1    Brantly, M.2    Pollock, D.3    Barker, A.4    Kueppers, F.5    Strange, C.6
  • 66
    • 33845227581 scopus 로고    scopus 로고
    • Alpha-1-antitrypsin deficiency: Optimal therapeutic regimen based on population pharmacokinetics
    • Soy D., de la Roza C., Lara B., Esquinas C., Torres A., Miravitlles M. Alpha-1-antitrypsin deficiency: Optimal therapeutic regimen based on population pharmacokinetics. Thorax 2006, 61:1059-1064.
    • (2006) Thorax , vol.61 , pp. 1059-1064
    • Soy, D.1    de la Roza, C.2    Lara, B.3    Esquinas, C.4    Torres, A.5    Miravitlles, M.6
  • 67
    • 33751067225 scopus 로고    scopus 로고
    • Pharmacokinetics of alpha1-antitrypsin replacement therapy in severe congenital emphysema
    • Vidal R., Padullés N., Sala F., Jardí R., Rodríguez F., Montoro J.B. Pharmacokinetics of alpha1-antitrypsin replacement therapy in severe congenital emphysema. Arch Bronconeumol 2006, 42:553-556.
    • (2006) Arch Bronconeumol , vol.42 , pp. 553-556
    • Vidal, R.1    Padullés, N.2    Sala, F.3    Jardí, R.4    Rodríguez, F.5    Montoro, J.B.6
  • 69
    • 33748653991 scopus 로고    scopus 로고
    • Alpha-1-antitrypsin replacement therapy: Current status
    • Abusriwil H., Stockley R.A. Alpha-1-antitrypsin replacement therapy: Current status. Curr Opin Pulm Med 2006, 12:125-131.
    • (2006) Curr Opin Pulm Med , vol.12 , pp. 125-131
    • Abusriwil, H.1    Stockley, R.A.2
  • 70
    • 33746192129 scopus 로고    scopus 로고
    • Deficient alpha-1-antitrypsin phenotypes and persistent airflow limitation in severe asthma
    • Van Veen I.H., ten Brinke A., van der Linden A.C., Rabe K.F., Bel E.H. Deficient alpha-1-antitrypsin phenotypes and persistent airflow limitation in severe asthma. Respir Med 2006, 100:1534-1539.
    • (2006) Respir Med , vol.100 , pp. 1534-1539
    • Van Veen, I.H.1    ten Brinke, A.2    van der Linden, A.C.3    Rabe, K.F.4    Bel, E.H.5
  • 71
    • 33746881048 scopus 로고    scopus 로고
    • Estimating the risk for alpha-1 antitrypsin deficiency among COPD patients: Evidence supporting targeted screening
    • De Serres F.J., Blanco I., Fernández-Bustillo E. Estimating the risk for alpha-1 antitrypsin deficiency among COPD patients: Evidence supporting targeted screening. COPD 2006, 3:133-139.
    • (2006) COPD , vol.3 , pp. 133-139
    • De Serres, F.J.1    Blanco, I.2    Fernández-Bustillo, E.3
  • 72
    • 34548071486 scopus 로고    scopus 로고
    • An overview of alpha-1 antitrypsin deficiency
    • Hericks A.J., Bhat A. An overview of alpha-1 antitrypsin deficiency. Mo Med 2007, 104:255-259.
    • (2007) Mo Med , vol.104 , pp. 255-259
    • Hericks, A.J.1    Bhat, A.2
  • 73
    • 35648984600 scopus 로고    scopus 로고
    • Aralast: An alpha 1-protease inhibitor for the treatment of alpha-antitrypsin deficiency
    • Mordwinkin N.M., Louie S.G. Aralast: An alpha 1-protease inhibitor for the treatment of alpha-antitrypsin deficiency. Expert Opin Pharmacother 2007, 8:2609-2614.
    • (2007) Expert Opin Pharmacother , vol.8 , pp. 2609-2614
    • Mordwinkin, N.M.1    Louie, S.G.2
  • 74
    • 36148968064 scopus 로고    scopus 로고
    • Development and results of the Spanish registry of patients with alpha-1-antitrypsin deficiency
    • Lara B., de la Roza C., Vilà S., Vidal R., Miravitlles M. Development and results of the Spanish registry of patients with alpha-1-antitrypsin deficiency. Int J Chron Obstruct Pulmon Dis 2007, 2:393-398.
    • (2007) Int J Chron Obstruct Pulmon Dis , vol.2 , pp. 393-398
    • Lara, B.1    de la Roza, C.2    Vilà, S.3    Vidal, R.4    Miravitlles, M.5
  • 75
    • 34547647784 scopus 로고    scopus 로고
    • Alpha one antitrypsin deficiency: From gene to treatment
    • Wood A.M., Stockley R.A. Alpha one antitrypsin deficiency: From gene to treatment. Respiration 2007, 74:481-492.
    • (2007) Respiration , vol.74 , pp. 481-492
    • Wood, A.M.1    Stockley, R.A.2
  • 76
    • 42149182337 scopus 로고    scopus 로고
    • Alpha-1 antitrypsin: Now available, but do we need it
    • Russi E.W. Alpha-1 antitrypsin: Now available, but do we need it. Swiss Med Wkly 2008, 138:191-196.
    • (2008) Swiss Med Wkly , vol.138 , pp. 191-196
    • Russi, E.W.1
  • 77
    • 59549098869 scopus 로고    scopus 로고
    • Detection of alpha-1 antitrypsin deficiency: A review
    • Aboussouan L.S., Stoller J.K. Detection of alpha-1 antitrypsin deficiency: A review. Respir Med 2009, 103:335-341.
    • (2009) Respir Med , vol.103 , pp. 335-341
    • Aboussouan, L.S.1    Stoller, J.K.2
  • 78
    • 74449091958 scopus 로고    scopus 로고
    • Safety and efficacy of alpha-1-antitrypsin augmentation therapy in the treatment of patients with alpha-1-antitrypsin deficiency
    • Petrache I., Hajjar J., Campos M. Safety and efficacy of alpha-1-antitrypsin augmentation therapy in the treatment of patients with alpha-1-antitrypsin deficiency. Biologics 2009, 3:193-204.
    • (2009) Biologics , vol.3 , pp. 193-204
    • Petrache, I.1    Hajjar, J.2    Campos, M.3
  • 79
    • 70350455493 scopus 로고    scopus 로고
    • Augmentation therapy in alpha-1 antitrypsin deficiency
    • Sandhaus R.A. Augmentation therapy in alpha-1 antitrypsin deficiency. COPD 2009, 6:147-148.
    • (2009) COPD , vol.6 , pp. 147-148
    • Sandhaus, R.A.1
  • 80
    • 67649390890 scopus 로고    scopus 로고
    • Alpha1-antitrypsin deficiency
    • Silverman E.K., Sandhaus R.A. Alpha1-antitrypsin deficiency. N Engl J Med 2009, 360:2749-2757.
    • (2009) N Engl J Med , vol.360 , pp. 2749-2757
    • Silverman, E.K.1    Sandhaus, R.A.2
  • 81
    • 85104566196 scopus 로고    scopus 로고
    • Augmentation therapy with alpha1-antitrypsin: Patterns of use and adverse events
    • Stoller J.K., Fallat R., Schluchter M.D., O'Brien R.G., Connor J.T., Gross N., et al. Augmentation therapy with alpha1-antitrypsin: Patterns of use and adverse events. Chest 2009, 136(5 Suppl):e30.
    • (2009) Chest , vol.136 , Issue.5
    • Stoller, J.K.1    Fallat, R.2    Schluchter, M.D.3    O'Brien, R.G.4    Connor, J.T.5    Gross, N.6
  • 82
    • 70349694399 scopus 로고    scopus 로고
    • Alpha1-antitrypsin deficiency: Best clinical practice
    • Kalsheker N.A. Alpha1-antitrypsin deficiency: Best clinical practice. J Clin Pathol 2009, 62:865-869.
    • (2009) J Clin Pathol , vol.62 , pp. 865-869
    • Kalsheker, N.A.1
  • 83
    • 77949329900 scopus 로고    scopus 로고
    • Alpha-1-antitrypsin augmentation therapy in deficient individuals enrolled in the Alpha-1 Foundation DNA and Tissue Bank
    • Tonelli A.R., Rouhani F., Li N., Schreck P., Brantly M.L. Alpha-1-antitrypsin augmentation therapy in deficient individuals enrolled in the Alpha-1 Foundation DNA and Tissue Bank. Int J Chron Obstruct Pulmon Dis 2009, 4:443-452.
    • (2009) Int J Chron Obstruct Pulmon Dis , vol.4 , pp. 443-452
    • Tonelli, A.R.1    Rouhani, F.2    Li, N.3    Schreck, P.4    Brantly, M.L.5
  • 85
    • 77952806527 scopus 로고    scopus 로고
    • Augmentation therapy for alpha-1 antitrypsin deficiency -not enough evidence to support its use yet!
    • McCarthy C., Dimitrov B.D. Augmentation therapy for alpha-1 antitrypsin deficiency -not enough evidence to support its use yet!. COPD 2010, 7:234.
    • (2010) COPD , vol.7 , pp. 234
    • McCarthy, C.1    Dimitrov, B.D.2
  • 86
    • 75849124048 scopus 로고    scopus 로고
    • Alpha1-antitrypsin deficiency: Forgotten etiology
    • Kaplan A., Cosentino L. Alpha1-antitrypsin deficiency: Forgotten etiology. Can Fam Physician 2010, 56:19-24.
    • (2010) Can Fam Physician , vol.56 , pp. 19-24
    • Kaplan, A.1    Cosentino, L.2
  • 87
    • 78349253871 scopus 로고    scopus 로고
    • Accelerated spirometric decline in New York City firefighters with a1-antitrypsin deficiency
    • Banauch G.I., Brantly M., Izbicki G., Hall C., Shanske A., Chavko R., et al. Accelerated spirometric decline in New York City firefighters with a1-antitrypsin deficiency. Chest 2010, 138:1116-1124.
    • (2010) Chest , vol.138 , pp. 1116-1124
    • Banauch, G.I.1    Brantly, M.2    Izbicki, G.3    Hall, C.4    Shanske, A.5    Chavko, R.6
  • 88
    • 78649460678 scopus 로고    scopus 로고
    • Emerging drugs for alpha-1-antitrypsin deficiency
    • Stockley R.A. Emerging drugs for alpha-1-antitrypsin deficiency. Expert Opin Emerg Drugs 2010, 15:685-694.
    • (2010) Expert Opin Emerg Drugs , vol.15 , pp. 685-694
    • Stockley, R.A.1
  • 89
    • 77957935340 scopus 로고    scopus 로고
    • Augmentation therapy in alpha-1 antitrypsin deficiency: Advances and controversies
    • Tonelli A.R., Brantly M.L. Augmentation therapy in alpha-1 antitrypsin deficiency: Advances and controversies. Ther Adv Respir Dis 2010, 4:289-312.
    • (2010) Ther Adv Respir Dis , vol.4 , pp. 289-312
    • Tonelli, A.R.1    Brantly, M.L.2
  • 90
    • 77957000718 scopus 로고    scopus 로고
    • COPD and alpha-1-antitrypsin deficiency
    • Lara B. COPD and alpha-1-antitrypsin deficiency. Arch Bronconeumol 2010, 46:2-8.
    • (2010) Arch Bronconeumol , vol.46 , pp. 2-8
    • Lara, B.1
  • 91
    • 77953319553 scopus 로고    scopus 로고
    • Alpha-1 antitrypsin deficiency: Whom to test, whom to treat
    • Sandhaus R.A. Alpha-1 antitrypsin deficiency: Whom to test, whom to treat. Semin Respir Crit Care Med 2010, 31:343-347.
    • (2010) Semin Respir Crit Care Med , vol.31 , pp. 343-347
    • Sandhaus, R.A.1
  • 92
    • 78349265383 scopus 로고    scopus 로고
    • α1-Antitrypsin protease inhibitor MZ heterozygosity is associated with airflow obstruction in two large cohorts
    • Sørheim I.C., Bakke P., Gulsvik A., Pillai S.G., Johannessen A., Gaarder P.I., et al. α1-Antitrypsin protease inhibitor MZ heterozygosity is associated with airflow obstruction in two large cohorts. Chest 2010, 138:1125-1132.
    • (2010) Chest , vol.138 , pp. 1125-1132
    • Sørheim, I.C.1    Bakke, P.2    Gulsvik, A.3    Pillai, S.G.4    Johannessen, A.5    Gaarder, P.I.6
  • 93
    • 79951631719 scopus 로고    scopus 로고
    • The role of augmentation therapy in alpha-1 antitrypsin deficiency
    • Kueppers F. The role of augmentation therapy in alpha-1 antitrypsin deficiency. Curr Med Res Opin 2011, 27:579-588.
    • (2011) Curr Med Res Opin , vol.27 , pp. 579-588
    • Kueppers, F.1
  • 94
    • 84856144387 scopus 로고    scopus 로고
    • Why has it been so difficult to prove the efficacy of alpha-1-antitrypsin replacement therapy Insights from the study of disease pathogenesis
    • Dickens J.A., Lomas D.A. Why has it been so difficult to prove the efficacy of alpha-1-antitrypsin replacement therapy Insights from the study of disease pathogenesis. Drug Des Devel Ther 2011, 5:391-405.
    • (2011) Drug Des Devel Ther , vol.5 , pp. 391-405
    • Dickens, J.A.1    Lomas, D.A.2
  • 96
    • 84859354170 scopus 로고    scopus 로고
    • Reduction of severe exacerbations and hospitalization-derived costs in alpha-1-antitrypsin-deficient patients treated with alpha-1-antitrypsin augmentation therapy
    • Investigators of the rEXA study group
    • Barros-Tizón J.C., Torres M.L., Blanco I., Martínez M.T. Reduction of severe exacerbations and hospitalization-derived costs in alpha-1-antitrypsin-deficient patients treated with alpha-1-antitrypsin augmentation therapy. Ther Adv Respir Dis 2012, 6:67-78. Investigators of the rEXA study group.
    • (2012) Ther Adv Respir Dis , vol.6 , pp. 67-78
    • Barros-Tizón, J.C.1    Torres, M.L.2    Blanco, I.3    Martínez, M.T.4
  • 97
    • 84862298546 scopus 로고    scopus 로고
    • Alpha-1-antitrypsin and other proteinase inhibitors
    • Miravitlles M. Alpha-1-antitrypsin and other proteinase inhibitors. Curr Opin Pharmacol 2012, 12:309-314.
    • (2012) Curr Opin Pharmacol , vol.12 , pp. 309-314
    • Miravitlles, M.1
  • 99
    • 84861319134 scopus 로고    scopus 로고
    • A review of augmentation therapy for alpha-1 antitrypsin deficiency
    • Mohanka M., Khemasuwan D., Stoller J.K. A review of augmentation therapy for alpha-1 antitrypsin deficiency. Expert Opin Biol Ther 2012, 12:685-700.
    • (2012) Expert Opin Biol Ther , vol.12 , pp. 685-700
    • Mohanka, M.1    Khemasuwan, D.2    Stoller, J.K.3
  • 100
    • 84859787234 scopus 로고    scopus 로고
    • α1-Proteinase inhibitor (human) in the treatment of hereditary emphysema secondary to α1-antitrypsin deficiency: Number and costs of years of life gained
    • Sclar D.A., Evans M.A., Robison L.M., Skaer T.L. α1-Proteinase inhibitor (human) in the treatment of hereditary emphysema secondary to α1-antitrypsin deficiency: Number and costs of years of life gained. Clin Drug Investig 2012, 32:353-360.
    • (2012) Clin Drug Investig , vol.32 , pp. 353-360
    • Sclar, D.A.1    Evans, M.A.2    Robison, L.M.3    Skaer, T.L.4
  • 101
    • 84875675170 scopus 로고    scopus 로고
    • The challenge of detecting alpha-1 antitrypsin deficiency
    • Stoller J.K., Brantly M. The challenge of detecting alpha-1 antitrypsin deficiency. COPD 2013, 10:26-34.
    • (2013) COPD , vol.10 , pp. 26-34
    • Stoller, J.K.1    Brantly, M.2
  • 102
    • 84875670108 scopus 로고    scopus 로고
    • Alpha-1 antitrypsin deficiency: The European experience
    • Stockley R.A., Dirksen A., Stolk J. Alpha-1 antitrypsin deficiency: The European experience. COPD 2013, 10:50-53.
    • (2013) COPD , vol.10 , pp. 50-53
    • Stockley, R.A.1    Dirksen, A.2    Stolk, J.3
  • 103
    • 84875668547 scopus 로고    scopus 로고
    • Alpha-1 antitrypsin augmentation therapy
    • Wewers M.D., Crystal R.G. Alpha-1 antitrypsin augmentation therapy. COPD 2013, 10:64-67.
    • (2013) COPD , vol.10 , pp. 64-67
    • Wewers, M.D.1    Crystal, R.G.2
  • 104
    • 84875646576 scopus 로고    scopus 로고
    • Airway disease in alpha-1 antitrypsin deficiency
    • Strange C. Airway disease in alpha-1 antitrypsin deficiency. COPD 2013, 10:68-73.
    • (2013) COPD , vol.10 , pp. 68-73
    • Strange, C.1
  • 105
    • 84887955432 scopus 로고    scopus 로고
    • Safety and pharmacokinetics of 120mg/kg versus 60mg/kg weekly intravenous infusions of alpha-1 proteinase inhibitor in alpha-1 antitrypsin deficiency: A multicenter, randomized, double-blind, crossover Study (SPARK)
    • Campos M.A., Kueppers F., Stocks J.M., Strange C., Chen J., Griffin R., et al. Safety and pharmacokinetics of 120mg/kg versus 60mg/kg weekly intravenous infusions of alpha-1 proteinase inhibitor in alpha-1 antitrypsin deficiency: A multicenter, randomized, double-blind, crossover Study (SPARK). COPD 2013, 10:687-695.
    • (2013) COPD , vol.10 , pp. 687-695
    • Campos, M.A.1    Kueppers, F.2    Stocks, J.M.3    Strange, C.4    Chen, J.5    Griffin, R.6
  • 106
    • 84880752065 scopus 로고    scopus 로고
    • Inhaled alpha 1-antitrypsin: Gauging patient interest in a new treatment
    • Monk R., Graves M., Williams P., Strange C. Inhaled alpha 1-antitrypsin: Gauging patient interest in a new treatment. COPD 2013, 10:411-415.
    • (2013) COPD , vol.10 , pp. 411-415
    • Monk, R.1    Graves, M.2    Williams, P.3    Strange, C.4
  • 107
    • 84885015158 scopus 로고    scopus 로고
    • Augmentation therapy for alpha-1 antitrypsin deficiency: Towards a personalised approach
    • Stockley R.A., Miravitlles M., Vogelmeier C. Augmentation therapy for alpha-1 antitrypsin deficiency: Towards a personalised approach. Orphanet J Rare Dis 2013, 8:149.
    • (2013) Orphanet J Rare Dis , vol.8 , pp. 149
    • Stockley, R.A.1    Miravitlles, M.2    Vogelmeier, C.3
  • 108
    • 33748305617 scopus 로고    scopus 로고
    • An official ATS statement: Grading the quality of evidence and strength of recommendations in ATS guidelines and recommendations
    • ATS Documents Development and Implementation Committee
    • Schünemann H.J., Jaeschke R., Cook D.J., Bria W.F., El-Solh A.A., Ernst A., et al. An official ATS statement: Grading the quality of evidence and strength of recommendations in ATS guidelines and recommendations. Am J Respir Crit Care Med 2006, 174:605-614. ATS Documents Development and Implementation Committee.
    • (2006) Am J Respir Crit Care Med , vol.174 , pp. 605-614
    • Schünemann, H.J.1    Jaeschke, R.2    Cook, D.J.3    Bria, W.F.4    El-Solh, A.A.5    Ernst, A.6
  • 110
    • 33144490691 scopus 로고    scopus 로고
    • Grading strength of recommendations and quality of evidence in clinical guidelines: Report from an American Colleg Chest Physicians Task Force
    • Guyatt G., Gutterman D., Baumann M.H., Adrizzo-Harris D., Hylek E.M., Phillips B., et al. Grading strength of recommendations and quality of evidence in clinical guidelines: Report from an American Colleg Chest Physicians Task Force. Chest 2006, 129:178-181.
    • (2006) Chest , vol.129 , pp. 178-181
    • Guyatt, G.1    Gutterman, D.2    Baumann, M.H.3    Adrizzo-Harris, D.4    Hylek, E.M.5    Phillips, B.6


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