Correlations between brain structure and symptom dimensions of psychosis in schizophrenia, schizoaffective, and psychotic bipolar i disorders

Schizophrenia Bulletin

Volumn 41, Issue 1, 2015, Pages 154-162

  Padmanabhan, Jaya L ^a,b   Tandon, Neeraj ^a,b   Haller, Chiara S ^a,b,c,d   Mathew, Ian T ^a,b   Eack, Shaun M ^e,f   Clementz, Brett A ^g   Pearlson, Godfrey D ^h,i   Sweeney, John A ^j,k   Tamminga, Carol A ^k   Keshavan, Matcheri S ^a,b,d  

^a BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^b MASSACHUSETTS MENTAL HEALTH CENTER   (United States)

^c HARVARD UNIVERSITY   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

^e UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^f UNIVERSITY OF PITTSBURGH   (United States)

^g UNIVERSITY OF GEORGIA   (United States)

^h YALE UNIVERSITY   (United States)

ⁱ INSTITUTE OF LIVING   (United States)

^j UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^k UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

more..

Author keywords

cortical thickness; gray matter; negative; positive; psychopathology; surface area

Indexed keywords

CHLORPROMAZINE;

ADULT; ANTHROPOMETRIC PARAMETERS; ARTICLE; BIPOLAR I DISORDER; BRAIN SIZE; BRAIN STRUCTURE; CORTICAL THICKNESS (BRAIN); DISEASE SEVERITY; FEMALE; GRAY MATTER; HUMAN; IMAGING SOFTWARE; INSULA; MAJOR CLINICAL STUDY; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; POSITIVE AND NEGATIVE SYNDROME SCALE; PRECUNEUS; PRIORITY JOURNAL; SCHIZOAFFECTIVE PSYCHOSIS; SCHIZOPHRENIA; SURFACE AREA; TEMPORAL LOBE; BIPOLAR DISORDER; BRAIN; FACTORIAL ANALYSIS; FRONTAL LOBE; MIDDLE AGED; ORGAN SIZE; PATHOLOGY; PSYCHOLOGY; PSYCHOSIS; YOUNG ADULT;

ADULT; BIPOLAR DISORDER; BRAIN; FACTOR ANALYSIS, STATISTICAL; FEMALE; FRONTAL LOBE; GRAY MATTER; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; ORGAN SIZE; PSYCHOTIC DISORDERS; SCHIZOPHRENIA; SCHIZOPHRENIC PSYCHOLOGY; TEMPORAL LOBE; YOUNG ADULT;

EID: 84928804179     PISSN: 05867614     EISSN: 17451701     Source Type: Journal    
DOI: 10.1093/schbul/sbu075     Document Type: Article

References (64)

1. Shepherd AM, Laurens KR, Matheson SL, Carr VJ, Green MJ. Systematic meta-review and quality assessment of the structural brain alterations in schizophrenia. Neurosci Biobehav Rev. 2012;36:1342-1356.
2. Selvaraj S, Arnone D, Job D, et al. Grey matter differences in bipolar disorder: a meta-analysis of voxel-based morphometry studies. Bipolar Disord. 2012;14:135-145.
3. Ellison-Wright I, Glahn DC, Laird AR, Thelen SM, Bullmore E. The anatomy of first-episode and chronic schizophrenia: an anatomical likelihood estimation meta-analysis. Am J Psychiatry. 2008;165:1015-1023.
4. Barta PE, Pearlson GD, Powers RE, Richards SS, Tune LE. Auditory hallucinations and smaller superior temporal gyral volume in schizophrenia. Am J Psychiatry. 1990;147:1457-1462.
5. Flaum M, O'Leary DS, Swayze VW, II, Miller DD, Arndt S, Andreasen NC. Symptom dimensions and brain morphology in schizophrenia and related psychotic disorders. J Psychiatr Res. 1995;29:261-276.
6. Lui S, Deng W, Huang X, et al. Association of cerebral deficits with clinical symptoms in antipsychotic-naive firstepisode schizophrenia: an optimized voxel-based morphometry and resting state functional connectivity study. Am J Psychiatry. 2009;166:196-205.
7. Nestor PG, Onitsuka T, Gurrera RJ, et al. Dissociable contributions of MRI volume reductions of superior temporal and fusiform gyri to symptoms and neuropsychology in schizophrenia. Schizophr Res. 2007;91:103-106.
8. Onitsuka T, Shenton ME, Salisbury DF, et al. Middle and inferior temporal gyrus gray matter volume abnormalities in chronic schizophrenia: an MRI study. Am J Psychiatry. 2004;161:1603-1611.
9. Turetsky B, Cowell PE, Gur RC, Grossman RI, Shtasel DL, Gur RE. Frontal and temporal lobe brain volumes in schizophrenia. Relationship to symptoms and clinical subtype. Arch Gen Psychiatry. 1995;52:1061-1070.
10. Fannon D, Chitnis X, Doku V, et al. Features of structural brain abnormality detected in first-episode psychosis. Am J Psychiatry. 2000;157:1829-1834.
11. Molina V, Reig S, Pascau J, et al. Anatomical and functional cerebral variables associated with basal symptoms but not risperidone response in minimally treated schizophrenia. Psychiatry Res. 2003;124:163-175.
12. Benoit A, Bodnar M, Malla AK, Joober R, Lepage M. The structural neural substrates of persistent negative symptoms in first-episode of non-affective psychosis: a voxel-based morphometry study. Front Psychiatry. 2012;3:42.
13. Baare WF, Hulshoff Pol HE, Hijman R, Mali WP, Viergever MA, Kahn RS. Volumetric analysis of frontal lobe regions in schizophrenia: relation to cognitive function and symptomatology. Biol Psychiatry. 1999;45:1597-1605.
14. Bora E, Fornito A, Radua J, et al. Neuroanatomical abnormalities in schizophrenia: a multimodal voxelwise meta-analysis and meta-regression analysis. Schizophr Res. 2011;127:46-57.
15. Lacerda AL, Hardan AY, Yorbik O, Vemulapalli M, Prasad KM, Keshavan MS. Morphology of the orbitofrontal cortex in first-episode schizophrenia: relationship with negative symptomatology. Prog Neuropsychopharmacol Biol Psychiatry. 2007;31:510-516.
16. Volpe U, Mucci A, Quarantelli M, Galderisi S, Maj M. Dorsolateral prefrontal cortex volume in patients with deficit or nondeficit schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry. 2012;37:264-269.
17. Nesvag R, Saetre P, Lawyer G, Jonsson EG, Agartz I. The relationship between symptom severity and regional cortical and grey matter volumes in schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry. 2009;33:482-490.
18. Kuperberg GR, Broome MR, McGuire PK, et al. Regionally localized thinning of the cerebral cortex in schizophrenia. Arch Gen Psychiatry. 2003;60:878-888.
19. Oertel-Knöchel V, Knöchel C, Rotarska-Jagiela A, et al. Association between psychotic symptoms and cortical thickness reduction across the schizophrenia spectrum. Cereb Cortex. 2013;23:61-70.
20. Rimol LM, Nesvag R, Hagler DJ, et al. Cortical volume, surface area, and thickness in schizophrenia and bipolar disorder. Biol Psychiatry. 2012;71:552-560.
21. Lyoo IK, Sung YH, Dager SR, et al. Regional cerebral cortical thinning in bipolar disorder. Bipolar Disord. 2006;8:65-74.
22. Rimol LM, Hartberg CB, Nesvag R, et al. Cortical thickness and subcortical volumes in schizophrenia and bipolar disorder. Biol Psychiatry. 2010;68:41-50.
23. Hartberg CB, Sundet K, Rimol LM, et al. Brain cortical thickness and surface area correlates of neurocognitive performance in patients with schizophrenia, bipolar disorder, and healthy adults. J Int Neuropsychol Soc. 2011;17:1080-1093.
24. Mountcastle VB. Modality and topographic properties of single neurons of cat's somatic sensory cortex. J Neurophysiol. 1957;20:408-434.
25. Rakic P. Specification of cerebral cortical areas. Science. 1988;241:170-176.
26. Rakic P. A small step for the cell, a giant leap for mankind: a hypothesis of neocortical expansion during evolution. Trends Neurosci. 1995;18:383-388.
27. Wierenga LM, Langen M, Oranje B, Durston S. Unique developmental trajectories of cortical thickness and surface area. Neuroimage. 2014;87:120-126.
28. Panizzon MS, Fennema-Notestine C, Eyler LT, et al. Distinct genetic influences on cortical surface area and cortical thickness. Cereb Cortex. 2009;19:2728-2735.
29. Xiao Y, Lui S, Deng W, et al. Altered cortical thickness related to clinical severity but not the untreated disease duration in schizophrenia [published online ahead of print December 18, 2013]. Schizophr Bull. doi: 10.1093/schbul/sbt177.
30. Padmanabhan J, Hooker CI, Keshavan MS. Brain evolution, language and psychopathology in schizophrenia. In: Brambilla P, Marini A, eds. Brain Evolution, Language and Psychopathology in Schizophrenia. New York: Routledge; 2013.
31. Tamminga CA, Ivleva EI, Keshavan MS, et al. Clinical phenotypes of psychosis in the Bipolar and Schizophrenia Network on Intermediate Phenotypes (B-SNIP). Am J Psychiatry. 2013;170:1263-1274.
32. Ivleva EI, Bidesi AS, Keshavan MS, et al. Gray matter volume as an intermediate phenotype for psychosis: Bipolar-Schizophrenia Network on Intermediate Phenotypes (B-SNIP). Am J Psychiatry. 2013;170:1285-1296.
33. First M, Spitzer R, Gibbon M, et al. The structured clinical interview for DSM-III-r personality disorders (SCID-II). Part II. Multi-site test-retest reliability study. J Pers Disord. 1995;9:92-104.
34. Kay SR, Fiszbein A, Opler LA. The positive and negative syndrome scale (PANSS) for schizophrenia. Schizophr Bull. 1987;13:261-276.
35. Fischl B. FreeSurfer. Neuroimage. 2012;62:774-781.
36. Hochberg Y. A sharper Bonferroni procedure for multiple tests of significance. Biometrika. 1988;75:800-802.
37. Yeh PH, Zhu H, Nicoletti MA, Hatch JP, Brambilla P, Soares JC. Structural equation modeling and principal component analysis of gray matter volumes in major depressive and bipolar disorders: differences in latent volumetric structure. Psychiatry Res. 2010;184:177-185.
38. Colibazzi T, Zhu H, Bansal R, Schultz RT, Wang Z, Peterson BS. Latent volumetric structure of the human brain: exploratory factor analysis and structural equation modeling of gray matter volumes in healthy children and adults. Hum Brain Mapp. 2008;29:1302-1312.
39. Fabrigar L, Wegener D, MacCallum R, Strahan E. Evaluating the use of exploratory factor analysis in psychological research. Psychol Methods. 1999;4:272-299.
40. Cattell R. The scree test for number of factors. Multivariate Behav Res. 1966;1:245-276.
41. Stevens J. Applied Multivariate Statistics for the Social Sciences. New York, NY: Routledge, Taylor & Francis Group, LLC; 2009.
42. Costello A, Osborne J. Best practices in exploratory factor analysis: four recommendations for getting the most out of your analysis. Pract Assess Res Eval. 2005;10:1-9.
43. Thurstone L. The Vectors of Mind. Chicago: University of Chicago Press; 1935.
44. Jardri R, Pouchet A, Pins D, Thomas P. Cortical activations during auditory verbal hallucinations in schizophrenia: a coordinate-based meta-analysis. Am J Psychiatry. 2011;168:73-81.
45. Palaniyappan L, Balain V, Radua J, Liddle PF. Structural correlates of auditory hallucinations in schizophrenia: a meta-analysis. Schizophr Res. 2012;137:169-173.
46. Shenton ME, Kikinis R, Jolesz FA, et al. Abnormalities of the left temporal lobe and thought disorder in schizophrenia. A quantitative magnetic resonance imaging study. N Engl J Med. 1992;327:604-612.
47. Andreasen NC, Nopoulos P, Magnotta V, Pierson R, Ziebell S, Ho BC. Progressive brain change in schizophrenia: a prospective longitudinal study of first-episode schizophrenia. Biol Psychiatry. 2011;70:672-679.
48. Iwashiro N, Suga M, Takano Y, et al. Localized gray matter volume reductions in the pars triangularis of the inferior frontal gyrus in individuals at clinical high-risk for psychosis and first episode for schizophrenia. Schizophr Res. 2012;137:124-131.
49. Suga M, Yamasue H, Abe O, et al. Reduced gray matter volume of Brodmann's Area 45 is associated with severe psychotic symptoms in patients with schizophrenia. Eur Arch Psychiatry Clin Neurosci. 2010;260:465-473.
50. Antonova E, Sharma T, Morris R, Kumari V. The relationship between brain structure and neurocognition in schizophrenia: a selective review. Schizophr Res. 2004;70:117-145.
51. Wible CG, Anderson J, Shenton ME, et al. Prefrontal cortex, negative symptoms, and schizophrenia: an MRI study. Psychiatry Res. 2001;108:65-78.
52. Berge D, Carmona S, Rovira M, Bulbena A, Salgado P, Vilarroya O. Gray matter volume deficits and correlation with insight and negative symptoms in first-psychotic-episode subjects. Acta Psychiatr Scand. 2011;123:431-439.
53. Chua SE, Wright IC, Poline JB, et al. Grey matter correlates of syndromes in schizophrenia. A semi-automated analysis of structural magnetic resonance images. Br J Psychiatry. 1997;170:406-410.
54. Lahti AC, Weiler MA, Holcomb HH, Tamminga CA, Carpenter WT, McMahon R. Correlations between rCBF and symptoms in two independent cohorts of drug-free patients with schizophrenia. Neuropsychopharmacology. 2006;31:221-230.
55. Rais M, van Haren NE, Cahn W, et al. Cannabis use and progressive cortical thickness loss in areas rich in CB1 receptors during the first five years of schizophrenia. Eur Neuropsychopharmacol. 2010;20:855-865.
56. Habets P, Marcelis M, Gronenschild E, Drukker M, van Os J, (G.R.O.U.P.) GRaOoP. Reduced cortical thickness as an outcome of differential sensitivity to environmental risks in schizophrenia. Biol Psychiatry. 2011;69:487-494.
57. Harrison PJ. The neuropathology of schizophrenia. A critical review of the data and their interpretation. Brain. 1999;122(Pt 4):593-624.
58. Glantz LA, Lewis DA. Decreased dendritic spine density on prefrontal cortical pyramidal neurons in schizophrenia. Arch Gen Psychiatry. 2000;57:65-73.
59. Pasternak O, Westin CF, Bouix S, et al. Excessive extracellular volume reveals a neurodegenerative pattern in schizophrenia onset. J Neurosci. 2012;32:17365-17372.
60. Lynall ME, Bassett DS, Kerwin R, et al. Functional connectivity and brain networks in schizophrenia. J Neurosci. 2010;30:9477-9487.
61. Lawrie SM, Buechel C, Whalley HC, Frith CD, Friston KJ, Johnstone EC. Reduced frontotemporal functional connectivity in schizophrenia associated with auditory hallucinations. Biol Psychiatry. 2002;51:1008-1011.
62. Ren W, Lui S, Deng W, et al. Anatomical and functional brain abnormalities in drug-naive first-episode schizophrenia. Am J Psychiatry. 2013;170:1308-1316.
63. Ho BC, Andreasen NC, Ziebell S, Pierson R, Magnotta V. Long-term antipsychotic treatment and brain volumes: a longitudinal study of first-episode schizophrenia. Arch Gen Psychiatry. 2011;68:128-137.
64. Hill SK, Reilly JL, Keefe RS, et al. Neuropsychological impairments in schizophrenia and psychotic bipolar disorder: findings from the Bipolar and Schizophrenia Network on Intermediate Phenotypes (B-SNIP) study. Am J Psychiatry. 2013;170:1275-1284.