메뉴 건너뛰기




Volumn 10, Issue 4, 2015, Pages

Maternal obesity in sheep increases fatty acid synthesis, upregulates nutrient transporters, and increases adiposity in adult male offspring after a feeding challenge

Author keywords

[No Author keywords available]

Indexed keywords

ACETIC ACID; CARBON 14; MESSENGER RNA; FATTY ACID;

EID: 84928803891     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0122152     Document Type: Article
Times cited : (44)

References (49)
  • 1
    • 23944462904 scopus 로고    scopus 로고
    • Obesity in pregnancy
    • ACOG committee opinion number 315 PMID: 16135613
    • ACOG committee opinion number 315. Obesity in pregnancy. Obstet Gynecol 2005; 106: 671-675. PMID: 16135613
    • (2005) Obstet Gynecol , vol.106 , pp. 671-675
  • 2
    • 31744449109 scopus 로고    scopus 로고
    • The prevalence and impact of overweight and obesity in an Australian obstetric population
    • PMID: 16411868
    • Callaway LK, Prins JB, Chang AM, Mclntyre HD. The prevalence and impact of overweight and obesity in an Australian obstetric population. Med J Aust 2006; 184: 56-59. PMID: 16411868
    • (2006) Med J Aust , vol.184 , pp. 56-59
    • Callaway, L.K.1    Prins, J.B.2    Chang, A.M.3    Mclntyre, H.D.4
  • 3
    • 33645523067 scopus 로고    scopus 로고
    • Prevalence of overweight and obesity in the United States, 1999-2004
    • PMID: 16595758
    • Ogden CL, Carroll MD, Curtin LR, McDowell MA, Tabak CJ, Flegal KM. Prevalence of overweight and obesity in the United States, 1999-2004. JAMA 2006; 295: 1549-1555. PMID: 16595758
    • (2006) JAMA , vol.295 , pp. 1549-1555
    • Ogden, C.L.1    Carroll, M.D.2    Curtin, L.R.3    McDowell, M.A.4    Tabak, C.J.5    Flegal, K.M.6
  • 4
    • 33748957030 scopus 로고    scopus 로고
    • Interpregnancy. Weight change and risk of adverse pregnancy outcomes: A population-based study
    • PMID: 17011943
    • Villamor E, Cnattingius S. Interpregnancy. Weight change and risk of adverse pregnancy outcomes: A population-based study. Lancet 2006; 368: 1164-1170. PMID: 17011943
    • (2006) Lancet , vol.368 , pp. 1164-1170
    • Villamor, E.1    Cnattingius, S.2
  • 5
    • 0345257102 scopus 로고    scopus 로고
    • Prevalence of overweight among children in Europe
    • PMID: 14649370
    • Lobstein T, Frelut ML. Prevalence of overweight among children in Europe. Obes. Rev. 2003; 4: 195-200. PMID: 14649370
    • (2003) Obes. Rev. , vol.4 , pp. 195-200
    • Lobstein, T.1    Frelut, M.L.2
  • 6
    • 0037048695 scopus 로고    scopus 로고
    • Prevalence and trends in overweight among us children and adolescents, 1999-2000
    • PMID: 12365956
    • Ogden CL, Flegal KM, Carroll MD, Johnson CL. Prevalence and trends in overweight among us children and adolescents, 1999-2000. JAMA 2002; 288: 1728-1732. PMID: 12365956
    • (2002) JAMA , vol.288 , pp. 1728-1732
    • Ogden, C.L.1    Flegal, K.M.2    Carroll, M.D.3    Johnson, C.L.4
  • 7
    • 4644310528 scopus 로고    scopus 로고
    • Predicting preschooler obesity at birth: The role of maternal obesity in early pregancy
    • PMID: 15231970
    • Whitaker RC. Predicting preschooler obesity at birth: the role of maternal obesity in early pregancy. Pediatrics 2004; 114: e29-e36. PMID: 15231970
    • (2004) Pediatrics , vol.114 , pp. e29-e36
    • Whitaker, R.C.1
  • 8
    • 20344382306 scopus 로고    scopus 로고
    • Metabolic syndrome in childhood: Association with birth weight, maternal obesity and gestation diabetes mellitus
    • PMID: 15741354
    • Boney CM, Verner A, Tucker R, Vohr BR. Metabolic syndrome in childhood: association with birth weight, maternal obesity and gestation diabetes mellitus. Pediatrics 2005; 115: E290-E296. PMID: 15741354
    • (2005) Pediatrics , vol.115 , pp. E290-E296
    • Boney, C.M.1    Verner, A.2    Tucker, R.3    Vohr, B.R.4
  • 9
    • 0028287629 scopus 로고
    • Perinatal hyperinsulinism as possible predisposing factor for diabetes mellitus, obesity and enhanced cardiovascular risk in later life
    • PMID: 8076902
    • Dorner G, Plagemann A. Perinatal hyperinsulinism as possible predisposing factor for diabetes mellitus, obesity and enhanced cardiovascular risk in later life. Horm Metab Res 1994; 26: 213-221. PMID: 8076902
    • (1994) Horm Metab Res , vol.26 , pp. 213-221
    • Dorner, G.1    Plagemann, A.2
  • 10
    • 21544444154 scopus 로고    scopus 로고
    • Birth weight and parental BMI predict overweight in children from mothers with gestational diabetes
    • PMID: 15983329
    • Schaefer-Graf UM, Pawliczak J, Passow D, Hartmann R, Rossi R, Buhrer C, et al. Birth weight and parental BMI predict overweight in children from mothers with gestational diabetes. Diabetes Care 2005; 28: 1745-1750. PMID: 15983329
    • (2005) Diabetes Care , vol.28 , pp. 1745-1750
    • Schaefer-Graf, U.M.1    Pawliczak, J.2    Passow, D.3    Hartmann, R.4    Rossi, R.5    Buhrer, C.6
  • 11
    • 43049127871 scopus 로고    scopus 로고
    • Developmental origins of obesity and the metabolic syndrome: The role of maternal obesity
    • PMID: 18230895
    • Armitage JA, Poston L, Taylor PD. Developmental origins of obesity and the metabolic syndrome: the role of maternal obesity. Front Horm Res 2008; 36: 73-84. doi: 10.1159/0000115355 PMID: 18230895
    • (2008) Front Horm Res , vol.36 , pp. 73-84
    • Armitage, J.A.1    Poston, L.2    Taylor, P.D.3
  • 12
    • 0037315781 scopus 로고    scopus 로고
    • Differential effects of fetal number and maternal nutrition in late gestation on prolactin receptor abundance and adipose tissue development in the neonatal lamb
    • PMID: 12538790
    • Budge HD, Mostyn J, Evens A, Watkins Y, Sullivan R, Ingleton C, et al. Differential effects of fetal number and maternal nutrition in late gestation on prolactin receptor abundance and adipose tissue development in the neonatal lamb. Pediatric Research 53: 2003;302-308. PMID: 12538790
    • (2003) Pediatric Research , vol.53 , pp. 302-308
    • Budge, H.D.1    Mostyn, J.2    Evens, A.3    Watkins, Y.4    Sullivan, R.5    Ingleton, C.6
  • 13
    • 34247884283 scopus 로고    scopus 로고
    • Maternal undernutrition during early to mid-gestation in the ewe results in altered growth, adiposity,and glucose tolerance in male offspring
    • PMID: 17224460
    • Ford SP, Hess BW, Schwope MM, Nijland MJ, Gilbert JS, Vonnahme KA, et al. Maternal undernutrition during early to mid-gestation in the ewe results in altered growth, adiposity,and glucose tolerance in male offspring. J Anim Sci 85: 2007;1285-1294. PMID: 17224460
    • (2007) J Anim Sci , vol.85 , pp. 1285-1294
    • Ford, S.P.1    Hess, B.W.2    Schwope, M.M.3    Nijland, M.J.4    Gilbert, J.S.5    Vonnahme, K.A.6
  • 14
    • 69249110098 scopus 로고    scopus 로고
    • Maternal obesity accelerates fetal pancreatic β-cell but not α-cell development in sheep: Prenatal consequences
    • PMID: 19605766
    • Ford SP, Zhang L, Zhu M, Miller MM, Smith DT, Hess BW, et al. Maternal obesity accelerates fetal pancreatic β-cell but not α-cell development in sheep: prenatal consequences. Am J Physiol Regul Integr Comp Physiol 2009; 297: R835-R843. doi: 10.1152/ajpregu.00072.2009 PMID: 19605766
    • (2009) Am J Physiol Regul Integr Comp Physiol , vol.297 , pp. R835-R843
    • Ford, S.P.1    Zhang, L.2    Zhu, M.3    Miller, M.M.4    Smith, D.T.5    Hess, B.W.6
  • 15
    • 78149485096 scopus 로고    scopus 로고
    • Maternal obesity markedly increases placental fatty acid transporter expression and fetal blood triglycerides at midgestation in the ewe
    • PMID: 20844260
    • Zhu MJ, Ma Y, Long NM, Du M, Ford SP. Maternal obesity markedly increases placental fatty acid transporter expression and fetal blood triglycerides at midgestation in the ewe. Am J Physiol Regul Integr Comp Physiol 2010; 229: R1224-R1231. doi: 10.1152/ajpregu.00309.2010 PMID: 20844260
    • (2010) Am J Physiol Regul Integr Comp Physiol , vol.229 , pp. R1224-R1231
    • Zhu, M.J.1    Ma, Y.2    Long, N.M.3    Du, M.4    Ford, S.P.5
  • 16
    • 84882595172 scopus 로고    scopus 로고
    • Maternal obesity upregulates fatty acid and glucose transporters and increases expression of enzymes mediating fatty acid biosynthesis in fetal adipose tissue depots
    • PMID: 22266999
    • Long NM, Rule DC, Zhu MJ, Nathanielsz PW, Ford SP. Maternal obesity upregulates fatty acid and glucose transporters and increases expression of enzymes mediating fatty acid biosynthesis in fetal adipose tissue depots. J Anim Sci 2012, 90: 2201-2210. doi: 10.2527/jas.2011-4343 PMID: 22266999
    • (2012) J Anim Sci , vol.90 , pp. 2201-2210
    • Long, N.M.1    Rule, D.C.2    Zhu, M.J.3    Nathanielsz, P.W.4    Ford, S.P.5
  • 17
    • 78049282026 scopus 로고    scopus 로고
    • Maternal obesity and increased nutrient intake before and during gestation in the ewe results in altered growth, adiposity, and glucose tolerance in adult offspring
    • PMID: 20622177
    • Long NM, George LA, Uthlaut AB, Smith DT, Nijland MJ, Nathanielsz PW, et al. Maternal obesity and increased nutrient intake before and during gestation in the ewe results in altered growth, adiposity, and glucose tolerance in adult offspring. J Anim Sci 2010; 88: 3546-3553. doi: 10.2527/jas.2010-3083 PMID: 20622177
    • (2010) J Anim Sci , vol.88 , pp. 3546-3553
    • Long, N.M.1    George, L.A.2    Uthlaut, A.B.3    Smith, D.T.4    Nijland, M.J.5    Nathanielsz, P.W.6
  • 19
    • 0027598195 scopus 로고
    • Relationship of body composition of mature ewes with condition score and body weight
    • PMID: 8505241
    • Sanson DW, West TR, Tatman WR, Riley ML, Judkins MB, Moss GE. Relationship of body composition of mature ewes with condition score and body weight. J Anim Sci 1993; 71: 1112-1116. PMID: 8505241
    • (1993) J Anim Sci , vol.71 , pp. 1112-1116
    • Sanson, D.W.1    West, T.R.2    Tatman, W.R.3    Riley, M.L.4    Judkins, M.B.5    Moss, G.E.6
  • 21
    • 84971946298 scopus 로고
    • A note on the effect of adipocyte size on in vitro lipogenesis from acetate and lactate in subcutaneous adipose tissue of large- and small-frame beef steers at 6 months of age
    • Rule DC, Beitz DC, Hood RL. A note on the effect of adipocyte size on in vitro lipogenesis from acetate and lactate in subcutaneous adipose tissue of large- and small-frame beef steers at 6 months of age. Anim Prod. 1987; 44: 454-456.
    • (1987) Anim Prod , vol.44 , pp. 454-456
    • Rule, D.C.1    Beitz, D.C.2    Hood, R.L.3
  • 22
    • 84855393676 scopus 로고    scopus 로고
    • Effects of early to mid gestational undernutrition with or without protein supplementation on offspring growth, carcass characteristics, and adipocyte size in beef cattle
    • PMID: 23365328
    • Long NM, Tousley CB, Underwood KR, Paisley SI, Means WJ, Hess BW, et al. Effects of early to mid gestational undernutrition with or without protein supplementation on offspring growth, carcass characteristics, and adipocyte size in beef cattle. J Anim Sci 2012; 90: 197-206. doi: 10.2527/jas.53907 PMID: 23365328
    • (2012) J Anim Sci , vol.90 , pp. 197-206
    • Long, N.M.1    Tousley, C.B.2    Underwood, K.R.3    Paisley, S.I.4    Means, W.J.5    Hess, B.W.6
  • 23
    • 77957240996 scopus 로고    scopus 로고
    • Effects of nutrient restriction of bovine dams during early gestation on postnatal growth, carcass and organ characteristics, and gene expression in adipose tissue and muscle
    • PMID: 20525929
    • Long NM, Prado-Cooper MJ, Krehbiel CR, Desilva, U, Wettemann RP. Effects of nutrient restriction of bovine dams during early gestation on postnatal growth, carcass and organ characteristics, and gene expression in adipose tissue and muscle. J Anim Sci 2010; 88: 3251-3261. doi: 10.2527/jas.2009-2512 PMID: 20525929
    • (2010) J Anim Sci , vol.88 , pp. 3251-3261
    • Long, N.M.1    Prado-Cooper, M.J.2    Krehbiel, C.R.3    Desilva, U.4    Wettemann, R.P.5
  • 24
    • 62149140183 scopus 로고    scopus 로고
    • Corn oil or corn grain supplementation to steers grazing endophyte-free tall fescue. II. Effects on subcutanous fatty acid content and lipogenic gene expression
    • PMID: 19028850
    • Ducket SK, Pratt SL, Pavan E. Corn oil or corn grain supplementation to steers grazing endophyte-free tall fescue. II. Effects on subcutanous fatty acid content and lipogenic gene expression. J Anim Sci 2009; 87: 1120-1128. doi: 10.2527/jas.2008-1420 PMID: 19028850
    • (2009) J Anim Sci , vol.87 , pp. 1120-1128
    • Ducket, S.K.1    Pratt, S.L.2    Pavan, E.3
  • 26
    • 0037566673 scopus 로고    scopus 로고
    • Comparison of acidic and alkaline catalysts for preparation of fatty acid methyl esters from ovine muscle with emphasis on conjugated linoleic acid
    • PMID: 22063245
    • Murrieta CM, Hess BW, Rule DC. Comparison of acidic and alkaline catalysts for preparation of fatty acid methyl esters from ovine muscle with emphasis on conjugated linoleic acid. Meat Sci 2003; 65: 523-529. doi: 10.1016/S0309-1740(02)00244-9 PMID: 22063245
    • (2003) Meat Sci , vol.65 , pp. 523-529
    • Murrieta, C.M.1    Hess, B.W.2    Rule, D.C.3
  • 27
    • 84886462809 scopus 로고    scopus 로고
    • Maternal obesity enhances white adipose tissue differentiation and alters genomic-scale DNA methylation in male rat offspring
    • PMID: 23959936
    • Borengasser SJ, Zhang Y, Kang P, Lindsey P, Ronis MJJ, Bader TM et al. Maternal obesity enhances white adipose tissue differentiation and alters genomic-scale DNA methylation in male rat offspring. Endocrinol 2013; 154: 4113-4125. doi: 10.1210/en.2012-2255 PMID: 23959936
    • (2013) Endocrinol , vol.154 , pp. 4113-4125
    • Borengasser, S.J.1    Zhang, Y.2    Kang, P.3    Lindsey, P.4    Ronis, M.J.J.5    Bader, T.M.6
  • 28
    • 78649451421 scopus 로고    scopus 로고
    • Maternal obesity in ewes results in reduced fetal pancreatic β-cell numbers in late gestation and decreased circulating insulin concentrations at term
    • Zhang L, Long NM, Hein SM, Ma Y, Nathanielsz PW, Ford SP. Maternal obesity in ewes results in reduced fetal pancreatic β-cell numbers in late gestation and decreased circulating insulin concentrations at term. Dom Anim Endo 2011; 40: 30-39.
    • (2011) Dom Anim Endo , vol.40 , pp. 30-39
    • Zhang, L.1    Long, N.M.2    Hein, S.M.3    Ma, Y.4    Nathanielsz, P.W.5    Ford, S.P.6
  • 29
    • 79960137207 scopus 로고    scopus 로고
    • Maternal obesity-impaired insulin signaling in sheep and induced lipid accumulation and fibrosis in skeletal muscle of offspring
    • PMID: 21349823
    • Yan X, Huang Y, Zhao JX, Long NM, Uthlaut AB, Zhu MJ et al. Maternal obesity-impaired insulin signaling in sheep and induced lipid accumulation and fibrosis in skeletal muscle of offspring. Biol Reprod 2011; 85: 172-178. doi: 10.1095/biolreprod.110.089649 PMID: 21349823
    • (2011) Biol Reprod , vol.85 , pp. 172-178
    • Yan, X.1    Huang, Y.2    Zhao, J.X.3    Long, N.M.4    Uthlaut, A.B.5    Zhu, M.J.6
  • 30
    • 33845609117 scopus 로고    scopus 로고
    • Increased maternal nutrition alters development of the appetite-regulating network in the brain
    • PMID: 16684802
    • Muhlhausler BS, Adam CL, Findlay PA, Duffield JA, McMillen IC. Increased maternal nutrition alters development of the appetite-regulating network in the brain. FASEB J 2006; 20: 1257-1259. PMID: 16684802
    • (2006) FASEB J , vol.20 , pp. 1257-1259
    • Muhlhausler, B.S.1    Adam, C.L.2    Findlay, P.A.3    Duffield, J.A.4    McMillen, I.C.5
  • 31
    • 67349223615 scopus 로고    scopus 로고
    • Established diet-induced obesity in female rats leads to offspring hyperphagia, adiposity and insulin resistance
    • PMID: 19288075
    • Nivoit P, Morens C, Van Assche FA, Jansen E, Poston L, Remacle C, et al. Established diet-induced obesity in female rats leads to offspring hyperphagia, adiposity and insulin resistance. Diabetologia 2009; 52: 1133-1142. doi: 10.1007/s00125-009-1316-9 PMID: 19288075
    • (2009) Diabetologia , vol.52 , pp. 1133-1142
    • Nivoit, P.1    Morens, C.2    Van Assche, F.A.3    Jansen, E.4    Poston, L.5    Remacle, C.6
  • 32
    • 38549152262 scopus 로고    scopus 로고
    • Diet-induced obesity in female mice leads to offspring hyperphagia, adiposity, hypertension, and insulin resistance
    • PMID: 18086952
    • Samuelsson A, Matthews PA, Argenton M, Christie MR, McConnell JM, Jansen EH, et al. Diet-induced obesity in female mice leads to offspring hyperphagia, adiposity, hypertension, and insulin resistance. Hypertension 2008; 51: 383-392. PMID: 18086952
    • (2008) Hypertension , vol.51 , pp. 383-392
    • Samuelsson, A.1    Matthews, P.A.2    Argenton, M.3    Christie, M.R.4    McConnell, J.M.5    Jansen, E.H.6
  • 35
    • 17844401180 scopus 로고    scopus 로고
    • Molecular and anatomic determinations of central leptin resistance
    • PMID: 15856064
    • Munzberg H, Myers MG. Molecular and anatomic determinations of central leptin resistance. Nat Neurosci 2005; 8: 566-570. PMID: 15856064
    • (2005) Nat Neurosci , vol.8 , pp. 566-570
    • Munzberg, H.1    Myers, M.G.2
  • 36
    • 0033931981 scopus 로고    scopus 로고
    • Two defects contribute to hypothalamic leptin resistance in mice with diet-induced obesity
    • PMID: 10862798
    • El-Haschimi K, Pierroz DD, Hileman SM, Bjørbaek C, Flier JS. Two defects contribute to hypothalamic leptin resistance in mice with diet-induced obesity. J Clin Invest 2000; 105: 1827-1832. PMID: 10862798
    • (2000) J Clin Invest , vol.105 , pp. 1827-1832
    • El-Haschimi, K.1    Pierroz, D.D.2    Hileman, S.M.3    Bjørbaek, C.4    Flier, J.S.5
  • 37
    • 72249092928 scopus 로고    scopus 로고
    • Recent advances in understanding leptin signaling and leptin resistance
    • PMID: 19724019
    • Morris DL, Rui L. Recent advances in understanding leptin signaling and leptin resistance. Am J Physiol Endocrinol Metab 2009; 297: E1247-E1259. doi: 10.1152/ajpendo.00274.2009 PMID: 19724019
    • (2009) Am J Physiol Endocrinol Metab , vol.297 , pp. E1247-E1259
    • Morris, D.L.1    Rui, L.2
  • 38
    • 66149118129 scopus 로고    scopus 로고
    • Hypothalamic proinflammatory lipid accumulation, inflammation, and insulin resistance in rats fed a high-fat diet
    • PMID: 19116375
    • Posey KA, Clegg DJ, Printz RL, Byun J, Morton GJ, Vivekanandan-Giri A, et al. Hypothalamic proinflammatory lipid accumulation, inflammation, and insulin resistance in rats fed a high-fat diet. Am J Physiol Endocrinol Metab 2009; 296: E1003-E1012. doi: 10.1152/ajpendo.90377.2008 PMID: 19116375
    • (2009) Am J Physiol Endocrinol Metab , vol.296 , pp. E1003-E1012
    • Posey, K.A.1    Clegg, D.J.2    Printz, R.L.3    Byun, J.4    Morton, G.J.5    Vivekanandan-Giri, A.6
  • 39
    • 0029881125 scopus 로고    scopus 로고
    • Cerebrospinal fluid leptin levels: Relationship to plasma levels and to adiposity in humans
    • PMID: 8616722
    • Schwartz MW, Peskind E, Raskind M, Boyko EJ, Porte D Jr. Cerebrospinal fluid leptin levels: relationship to plasma levels and to adiposity in humans. Nat Med 1996; 2: 589-593. PMID: 8616722
    • (1996) Nat Med , vol.2 , pp. 589-593
    • Schwartz, M.W.1    Peskind, E.2    Raskind, M.3    Boyko, E.J.4    Porte, D.5
  • 40
    • 52949096557 scopus 로고    scopus 로고
    • Hypothalamic IKKbeta/NF-kappa B and ER stress link overnutrition to energy imbalance and obesity
    • Zhang X, Zhang G, Zhang H, Karin M, Bai H, Cai D. Hypothalamic IKKbeta/NF-kappa B and ER stress link overnutrition to energy imbalance and obesity. Cell 2008; 135: 61-73.
    • (2008) Cell , vol.135 , pp. 61-73
    • Zhang, X.1    Zhang, G.2    Zhang, H.3    Karin, M.4    Bai, H.5    Cai, D.6
  • 41
    • 79952604150 scopus 로고    scopus 로고
    • Maternal obesity eliminates the neonatal lamb plasma leptin peak
    • PMID: 21262878
    • Long NM, Ford SP, Nathanielsz PW. Maternal obesity eliminates the neonatal lamb plasma leptin peak. J Physiology 2011; 589: 1455-1462. doi: 10.1113/jphysiol.2010.201681 PMID: 21262878
    • (2011) J Physiology , vol.589 , pp. 1455-1462
    • Long, N.M.1    Ford, S.P.2    Nathanielsz, P.W.3
  • 42
    • 38549134585 scopus 로고    scopus 로고
    • Maternal perinatal undernutrition drastically reduces postnatal leptin surge and affects the development of arcuate nucleus proopiomelanocortin neurons in neonatal male rat pups
    • Delahaye F, Breton C, Risold PY, Enache M, Dutriez-Casteloot I, Laborie C, et al. Maternal perinatal undernutrition drastically reduces postnatal leptin surge and affects the development of arcuate nucleus proopiomelanocortin neurons in neonatal male rat pups. Endocrinol 2008; 149: 470-475.
    • (2008) Endocrinol , vol.149 , pp. 470-475
    • Delahaye, F.1    Breton, C.2    Risold, P.Y.3    Enache, M.4    Dutriez-Casteloot, I.5    Laborie, C.6
  • 43
    • 0032436307 scopus 로고    scopus 로고
    • Leptin activates hypothalamic CART neurons projecting to the spinal cord
    • PMID: 9883730
    • Elias CF, Lee C, Kelly J, Aschkenasi C, Ahima RS, Couceyro PR, et al. Leptin activates hypothalamic CART neurons projecting to the spinal cord. Neuron 1998; 21: 1375-1385. PMID: 9883730
    • (1998) Neuron , vol.21 , pp. 1375-1385
    • Elias, C.F.1    Lee, C.2    Kelly, J.3    Aschkenasi, C.4    Ahima, R.S.5    Couceyro, P.R.6
  • 45
    • 67649958535 scopus 로고    scopus 로고
    • Maternal obesity induced by diet in rats permanently influences central processes regulating food intake in offspring
    • PMID: 19516909
    • Kirk SL, Samuelsson AM, Argenton M, Dhonye H, Kalamatiano T, Poston L. Maternal obesity induced by diet in rats permanently influences central processes regulating food intake in offspring. PLOS ONE 2009; 4: e5870. doi: 10.1371/journal.pone.0005870 PMID: 19516909
    • (2009) PLOS ONE , vol.4 , pp. e5870
    • Kirk, S.L.1    Samuelsson, A.M.2    Argenton, M.3    Dhonye, H.4    Kalamatiano, T.5    Poston, L.6
  • 46
    • 0034751333 scopus 로고    scopus 로고
    • High neonatal leptin exposure enhances brain GR expression and feedback efficacy on the adrenocortical axis of developing rats
    • PMID: 11606425
    • Proulx K, Clavel S, Nault G, Richard D, Walker CD. High neonatal leptin exposure enhances brain GR expression and feedback efficacy on the adrenocortical axis of developing rats. Endocrinol 2001; 142: 4607-4616. PMID: 11606425
    • (2001) Endocrinol , vol.142 , pp. 4607-4616
    • Proulx, K.1    Clavel, S.2    Nault, G.3    Richard, D.4    Walker, C.D.5
  • 47
    • 24144486246 scopus 로고    scopus 로고
    • Role of premature leptin surge in obesity resulting from intrauterine undernutrition
    • PMID: 16054086
    • Yura S, Itoh H, Sagawa N, Yamamoto H, Masuzaki H, Nakao K, et al. Role of premature leptin surge in obesity resulting from intrauterine undernutrition. Cell Metabolism 2005; 1: 371-378. PMID: 16054086
    • (2005) Cell Metabolism , vol.1 , pp. 371-378
    • Yura, S.1    Itoh, H.2    Sagawa, N.3    Yamamoto, H.4    Masuzaki, H.5    Nakao, K.6
  • 48
    • 33646460772 scopus 로고    scopus 로고
    • Neonatal leptin treatment programs leptin hypothalamic resistance and intermediary metabolic parameters in adult rat
    • PMID: 16571164
    • Toste FP, de Moura EG, Lisboa PC, Fagundes AT, de Oliveira E, Passos MCF. Neonatal leptin treatment programs leptin hypothalamic resistance and intermediary metabolic parameters in adult rat. Br J Nutr 2006; 95: 830-837. PMID: 16571164
    • (2006) Br J Nutr , vol.95 , pp. 830-837
    • Toste, F.P.1    De Moura, E.G.2    Lisboa, P.C.3    Fagundes, A.T.4    De Oliveira, E.5    Passos, M.C.F.6
  • 49
    • 79955584321 scopus 로고    scopus 로고
    • Leptin and central nervous system control of glucose metabolism
    • PMID: 21527729
    • Morton GJ, Schwartz MW. Leptin and central nervous system control of glucose metabolism. Physiol Rev 2011; 91: 389-411. doi: 10.1152/physrev.00007.2010 PMID: 21527729
    • (2011) Physiol Rev , vol.91 , pp. 389-411
    • Morton, G.J.1    Schwartz, M.W.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.