Interaction of W-substituted analogs of cyclo-RRRWFW with bacterial lipopolysaccharides: The role of the aromatic cluster in antimicrobial activity

Antimicrobial Agents and Chemotherapy

Volumn 55, Issue 2, 2011, Pages 788-797

  Bagheri, Mojtaba ^a   Keller, Sandro ^a,b   Dathe, Margitta ^a  

^a LEIBNIZ INSTITUT FÜR MOLEKULARE PHARMAKOLOGIE   (Germany)

^b France   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

1 METHYL LEVO TRYPTOPHAN; 1 PALMITOYL 2 OLEOYL SN GLYCERO 3 [PHOSPHO RAC (1 GLYCEROL)]; 1 PALMITOYL 2 OLEOYL SN GLYCERO 3 PHOSPHOCHOLINE; 5 FLUORO LEVO TRYPTOPHAN; 5 METHOXY LEVO TRYPTOPHAN; 5 METHYL DEXTRO LEVO TRYPTOPHAN; ALPHA (2 INDANYL)GLYCINE; BACTERIUM LIPOPOLYSACCHARIDE; BETA (BENZOTHIEN 3 YL) ALANINE; DIHYDROTRYPTOPHAN; LIPID A; POLYPEPTIDE ANTIBIOTIC AGENT; UNCLASSIFIED DRUG;

ANTIMICROBIAL ACTIVITY; ARTICLE; BACILLUS SUBTILIS; BACTERIAL MEMBRANE; CONTROLLED STUDY; DRUG PROTEIN BINDING; DRUG STRUCTURE; ENTHALPY; ENTROPY; ESCHERICHIA COLI; HEMOLYSIS; HYDROGEN BOND; HYDROPHOBICITY; ISOTHERMAL TITRATION CALORIMETRY; LIPID BILAYER; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANTI-BACTERIAL AGENTS; BACILLUS SUBTILIS; CALORIMETRY; CELL MEMBRANE; CELL MEMBRANE PERMEABILITY; ESCHERICHIA COLI; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; LIPOPOLYSACCHARIDES; MICROBIAL SENSITIVITY TESTS; PEPTIDES, CYCLIC; PROTEIN CONFORMATION; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 78751687696     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.01098-10     Document Type: Article

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