Paeonolum protects against MPP+-induced neurotoxicity in zebrafish and PC12 cells

BMC Complementary and Alternative Medicine

Volumn 15, Issue 1, 2015, Pages

  Lu, Xi Lin ^a   Lin, Yue Hao ^b   Wu, Qi ^a   Su, Feng Juan ^a   Ye, Cheng Hui ^a   Shi, Lei ^a   He, Bai Xuan ^a   Huang, Fei Wen ^a   Pei, Zhong ^a   Yao, Xiao Li ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b SUN YAT SEN UNIVERSITY CANCER CENTER   (China)

Author keywords

Mitochondrial; MPP+; Paeonolum; ROS; Total GSH; Zebrafish

Indexed keywords

CASPASE 3; CYTOCHROME C; GLUTATHIONE; GREEN FLUORESCENT PROTEIN; PAEONIA SUFFRUTICOSA EXTRACT; REACTIVE OXYGEN METABOLITE; 1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; ANTIOXIDANT; DOPAMINE; NEUROPROTECTIVE AGENT; NEUROTOXIN; PLANT EXTRACT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIOXIDANT ACTIVITY; ARTICLE; CELL CULTURE; CELL DEATH; CELL STRUCTURE; CELL VIABILITY; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; ENZYME ACTIVITY; ENZYME RELEASE; IMMUNOBLOTTING; LOCOMOTION; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; MONOAMINE NERVE CELL; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PAEONIA SUFFRUTICOSA; PC12 CELL LINE; RAT; ZEBRA FISH; ANIMAL; CHEMISTRY; DRUG EFFECTS; HUMAN; METABOLISM; MPTP POISONING; PAEONIA; PARKINSON DISEASE; PHYTOTHERAPY;

1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE; ANIMALS; ANTIOXIDANTS; CASPASE 3; CELL DEATH; CYTOCHROMES C; DOPAMINE; DOPAMINERGIC NEURONS; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; MPTP POISONING; NEUROPROTECTIVE AGENTS; NEUROTOXINS; OXIDATIVE STRESS; PAEONIA; PARKINSON DISEASE; PC12 CELLS; PHYTOTHERAPY; PLANT EXTRACTS; RATS; REACTIVE OXYGEN SPECIES; ZEBRAFISH;

EID: 84928790644     PISSN: None     EISSN: 14726882     Source Type: Journal    
DOI: 10.1186/s12906-015-0661-0     Document Type: Article

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