A randomized trial comparing the diagnostic accuracy of visual inspection with acetic acid to visual inspection with Lugol's iodine for cervical cancer screening in HIV infected women

PLoS ONE

Volumn 10, Issue 4, 2015, Pages

  Huchko, Megan J ^a   Sneden, Jennifer ^a   Zakaras, Jennifer M ^a   Smith McCune, Karen ^a   Sawaya, George ^a   Maloba, May ^b   Bukusi, Elizabeth Ann ^b,c   Cohen, Craig R ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b KENYA MEDICAL RESEARCH INSTITUTE   (Kenya)

^c UNIVERSITY OF NAIROBI   (Kenya)

Author keywords

[No Author keywords available]

Indexed keywords

ABACAVIR PLUS LAMIVUDINE PLUS RITONAVIR; ACETIC ACID; ANTIRETROVIRUS AGENT; EFAVIRENZ PLUS LAMIVUDINE PLUS STAVUDINE; EFAVIRENZ PLUS LAMIVUDINE PLUS TENOFIVIR; EFAVIRENZ PLUS LAMIVUDINE PLUS TENOFOVIR DISOPROXIL; LAMIVUDINE PLUS LOPINAVIR PLUS RITONAVIR; LAMIVUDINE PLUS NEVIRAPINE PLUS STAVUDINE; LAMIVUDINE PLUS NEVIRAPINE PLUS TENOFOVIR DISOPROXIL; LOPINAVIR PLUS RITONAVIR; LUGOL; UNCLASSIFIED DRUG; ZIDOVUDINE; COLORING AGENT; IODIDE; LUGOL'S SOLUTION;

ADULT; AGE; AGED; ARTICLE; CANCER SCREENING; CD4 LYMPHOCYTE COUNT; COHORT ANALYSIS; COLPOSCOPY; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST ACCURACY STUDY; FEMALE; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INTERMETHOD COMPARISON; KENYA; MAJOR CLINICAL STUDY; PREDICTIVE VALUE; RANDOMIZED CONTROLLED TRIAL; SENSITIVITY AND SPECIFICITY; TUMOR BIOPSY; UTERINE CERVIX CARCINOMA IN SITU; VISUAL INSPECTION WITH ACETIC ACID; VISUAL INSPECTION WITH LUGOL IODINE; CERVICAL INTRAEPITHELIAL NEOPLASIA; COMPARATIVE STUDY; COMPLICATION; EARLY CANCER DIAGNOSIS; HUMAN IMMUNODEFICIENCY VIRUS; MASS SCREENING; METABOLISM; PATHOGENICITY; PROCEDURES; UTERINE CERVICAL DYSPLASIA; UTERINE CERVICAL NEOPLASMS; VAGINA SMEAR; VIROLOGY;

ACETIC ACID; ADULT; CERVICAL INTRAEPITHELIAL NEOPLASIA; COLORING AGENTS; COLPOSCOPY; EARLY DETECTION OF CANCER; FEMALE; HIV; HIV INFECTIONS; HUMANS; IODIDES; MASS SCREENING; UTERINE CERVICAL DYSPLASIA; UTERINE CERVICAL NEOPLASMS; VAGINAL SMEARS;

EID: 84928781101     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0118568     Document Type: Article

References (35)

1. Bruni L, Barrionuevo-Rosas L, Serrano B, Brotons M, Cosano R, et al. (2014) Human Papillomavirus and Related Diseases in Kenya. Summary Report 2014-03- 17.
2. Ferlay J, Shin H, Bray F, Forman D, Mathers C, et al. (2010) GLOBOCAN 2008 v2.0, Cancer Incidence and Mortality Worldwide: IARC CancerBase No. 10. Lyon, France: International Agency for Research on Cancer, 2010. Available: http://globocan.iarc.fr. Accessed 2013 December 21.
3. Adefuye PO, Broutet NJ, de Sanjose S, Denny LA (2013) Trials and projects on cervical cancer and human papillomavirus prevention in sub-Saharan Africa. Vaccine 31 Suppl 5: F53-59. doi: 10.1016/j. vaccine.2012.06.070 PMID: 24331748
4. Ezechi OC, Ostergren PO, Nwaokorie FO, Ujah IA, Odberg Pettersson K (2014) The burden, distribution and risk factors for cervical oncogenic human papilloma virus infection in HIV positive Nigerian women. Virology journal 11: 5. doi: 10.1186/1743-422X-11-5 PMID: 24433568
5. Franceschi S, Jaffe H (2007) Cervical cancer screening of women living with HIV infection: a must in the era of antiretroviral therapy. Clinical infectious diseases: an official publication of the Infectious Diseases Society of America 45: 510-513.
6. Sherris J. , WittetS., KleineA., SellorsJ., LucianiS., et al. (2009) Evidence-based, alternative cervical cancer screening approaches in low-resource settings. International Perspectives on Sexual and Reproductive Health 35: 147-154. doi: 10.1363/ifpp.35.147.09 PMID: 19805020
7. - (2013) WHO guidelines for screening and treatment of precancerous lesions for cervical cancer prevention. Geneva: World Health Organization.
8. Sankaranarayanan R, Nene BM, Shastri SS, Jayant K, Muwonge R, et al. (2009) HPV screening for cervical cancer in rural India. The New England journal of medicine 360: 1385-1394. doi: 10.1056/ NEJMoa0808516 PMID: 19339719
9. Belinson JL, Pretorius RG, Zhang WH, Wu LY, Qiao YL, et al. (2001) Cervical cancer screening by simple visual inspection after acetic acid. Obstetrics and Gynecology 98: 441-444. PMID: 11530126
10. Goldie SJ, Gaffikin L, Goldhaber-Fiebert JD, Gordillo-Tobar A, Levin C, et al. (2005) Cost-effectiveness of cervical-cancer screening in five developing countries. N Eng J Med 353: 2158-2168. PMID: 16291985
11. Wright TC, Jr., Denny L, Kuhn L, Goldie S (2002) Use of visual screening methods for cervical cancer screening. Obstetrics and gynecology clinics of North America 29: 701-734. PMID: 12509093
12. Ghosh P, Gandhi G, Kochhar PK, Zutshi V, Batra S (2012) Visual inspection of cervix with Lugol's iodine for early detection of premalignant & malignant lesions of cervix. The Indian journal of medical research 136: 265-271. PMID: 22960894
13. Sankaranarayanan R, Basu P, Wesley RS, Mahe C, Keita N, et al. (2004) Accuracy of visual screening for cervical neoplasia: Results from an IARC multicentre study in India and Africa. International journal of cancer Journal international du cancer 110: 907-913. PMID: 15170675
14. Consul S, Agrawal A, Sharma H, Bansal A, Gutch M, et al. (2012) Comparative study of effectiveness of Pap smear versus visual inspection with acetic acid and visual inspection with Lugol's iodine for mass screening of premalignant and malignant lesion of cervix. Indian journal of medical and paediatric oncology: official journal of Indian Society of Medical & Paediatric Oncology 33: 161-165.
15. Lewis KC, Tsu VD, Dawa A, Kidula NA, Chami IN, et al. (2011) A comparison of triage methods for Kenyan women who screen positive for cervical intraepithelial neoplasia by visual inspection of the cervix with acetic acid. African health sciences 11: 362-369. PMID: 22275925
16. Bradford L, Goodman A (2013) Cervical cancer screening and prevention in low-resource settings. Clinical Obstetrics and Gynecology 56: 76-87. doi: 10.1097/GRF.0b013e31828237ac PMID: 23337844
17. Sankaranarayanan R, Wesley R, Thara S, Dhakad N, Chandralekha B, et al. (2003) Test characteristics of visual inspection with 4% acetic acid (VIA) and Lugol's iodine (VILI) in cervical cancer screening in Kerala, India. International journal of cancer Journal international du cancer 106: 404-408. PMID: 12845681
18. Shastri SS, Dinshaw K, Amin G, Goswami S, Patil S, et al. (2005) Concurrent evaluation of visual, cytological and HPV testing as screening methods for the early detection of cervical neoplasia in Mumbai, India. Bulletin of the World Health Organization 83: 186-194. PMID: 15798842
19. Cervical Cancer Action. Progress in cervical cancer prevention: The CCA report card. 2012. Available: http://www.cervicalcanceraction.org/pubs/pubs.php. Accessed 2014 June.
20. Sankaranarayanan R, Nessa A, Esmy PO, Dangou JM (2012) Visual inspection methods for cervical cancer prevention. Best practice & research Clinical obstetrics & gynaecology 26: 221-232.
21. Ngoma T, Muwonge R, Mwaiselage J, Kawegere J, Bukori P, et al. (2010) Evaluation of cervical visual inspection screening in Dar es Salaam, Tanzania. International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 109: 100-104. doi: 10. 1016/j.ijgo.2009.11.025 PMID: 20152973
22. Muwonge R, Manuel Mda G, Filipe AP, Dumas JB, Frank MR, et al. (2010) Visual screening for early detection of cervical neoplasia in Angola. International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 111: 68-72. doi: 10.1016/j.ijgo. 2010.04.024 PMID: 20570259
23. Maiman M, Fruchter RG, Sedlis A, Feldman J, Chen P, et al. (1998) Prevalence, risk factors, and accuracy of cytologic screening for cervical intraepithelial neoplasia in women with the human immunodeficiency virus. Gynecologic Oncology 68: 233-239. PMID: 9570972
24. World Health Organization (2007) Training modules for the syndromic management of sexually transmitted infections. Geneva.
25. Kurman RJ, Carcangiu ML, Herrington CS, Young RH (2014) WHO Classification of Tumours of Female Reproductive Organs. Fourth Edition; IARC, editor. Geneva: IARC. 307 p. PMID: 25567588
26. Huchko MJ, Bukusi EA, Cohen CR (2011) Building capacity for cervical cancer screening in outpatient HIV clinics in the Nyanza province of western Kenya. International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 114: 106-110. doi: 10.1016/j.ijgo.2011.02.009 PMID: 21620403
27. De Vuyst H, Claeys P, Njiru S, Muchiri L, Steyaert S, et al. (2005) Comparison of pap smear, visual inspection with acetic acid, human papillomavirus DNA-PCR testing and cervicography. International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 89: 120-126. PMID: 15847874
28. Sahasrabuddhe VV, Bhosale RA, Kavatkar AN, Nagwanshi CA, Joshi SN, et al. (2012) Comparison of visual inspection with acetic acid and cervical cytology to detect high-grade cervical neoplasia among HIV-infected women in India. International journal of cancer Journal international du cancer 130: 234-240. doi: 10.1002/ijc.25971 PMID: 21387289
29. Joshi S, Sankaranarayanan R, Muwonge R, Kulkarni V, Somanathan T, et al. (2013) Screening of cervical neoplasia in HIV-infected women in India. AIDS 27: 607-615. doi: 10.1097/QAD. 0b013e32835b1041 PMID: 23079814
30. Firnhaber C, Mayisela N, Mao L, Williams S, Swarts A, et al. (2013) Validation of Cervical Cancer Screening Methods in HIV Positive Women from Johannesburg South Africa. PloS one 8: e53494. doi: 10.1371/journal.pone.0053494 PMID: 23326441
31. Chung M.H. , McKenzieK.P., De VuystH., RichardsonB.A., RanaF., et al. (2013) Comparing Pap Smear, Via, and Hpv Cervical Cancer Screening Methods among Hiv-positive Women by Immune Status and Antiretroviral Therapy. AIDS.
32. - (2012) Prevention of cervical cancer through screening using visual inspection with acetic acid (VIA) and treatment with cryotherapy. A demonstration project in six African countries: Malawi, Madagascar, Nigeria, Uganda, the United Republic of Tanzania and Zambia. Geneva: World Health Organization.
33. Kenya Ministry of Health and Sanitation and Ministry of Medical Services (2011) National Cervical Cancer Prevention Program Action Plan: 2011-2015. Nairobi.
34. Pretorius RG, Belinson JL, Azizi F, Peterson PC, Belinson S (2012) Utility of random cervical biopsy and endocervical curettage in a low-risk population. Journal of lower genital tract disease 16: 333-338. doi: 10.1097/LGT.0b013e3182480c18 PMID: 22622343
35. Pretorius RG, Zhang WH, Belinson JL, Huang MN, Wu LY, et al. (2004) Colposcopically directed biopsy, random cervical biopsy, and endocervical curettage in the diagnosis of cervical intraepithelial neoplasia II or worse. American Journal of Obstetrics and Gynecology 191: 430-434. PMID: 15343217