Gender-specific differences in Adamantiades-Behçet's disease manifestations: An analysis of the german registry and meta-analysis of data from the literature

Rheumatology (United Kingdom)

Volumn 54, Issue 1, 2014, Pages 121-133

  Bonitsis, Nikolaos G ^a,b   Luong Nguyen, Liem B ^c   Lavalley, Michael P ^d   Papoutsis, Nestor ^b   Altenburg, Andreas ^a,b   Kötter, Ina ^b   Micheli, Christiana ^a   Maldini, Carla ^c   Mahr, Alfred ^c,e   Zouboulis, Christos C ^a,b  

^a DESSAU MEDICAL CENTER   (Germany)

^b German Registry of Adamantiades Behçet's Disease   (Germany)

^c SAINT LOUIS HOSPITAL   (France)

^d BOSTON UNIVERSITY   (United States)

^e PARIS DESCARTES UNIVERSITY   (France)

Author keywords

Adamantiades Beh et's disease; Beh et's disease; Beh et's syndrome; Gender; Meta analysis; Sex factors

Indexed keywords

HLA B ANTIGEN; HLA B5 ANTIGEN; UNCLASSIFIED DRUG;

ADAMANTIADES BEHCET DISEASE; ARTHROPATHY; ARTICLE; BEHCET DISEASE; DEEP VEIN THROMBOSIS; DISEASE ASSOCIATION; ERYTHEMA NODOSUM; ETHNICITY; EYE DISEASE; FOLLICULITIS; GENITAL ULCER; HEART DISEASE; HUMAN; MULTICENTER STUDY (TOPIC); PAPULE; PATIENT SATISFACTION; PHENOTYPE; PRIORITY JOURNAL; PUSTULE; REGISTER; RISK FACTOR; SEX DIFFERENCE; SYSTEMATIC REVIEW; VASCULAR DISEASE;

EID: 84928747412     PISSN: 14620324     EISSN: 14620332     Source Type: Journal    
DOI: 10.1093/rheumatology/keu247     Document Type: Article

References (75)

1. Yurdakul S, Yazici H. Behcet's syndrome. Best Pract Res Clin Rheumatol 2008;22:793-809.
2. Kapsimali VD, Kanakis MA, Vaiopoulos GA, Kaklamanis PG. Etiopathogenesis of Behcet's disease with emphasis on the role of immunological aberrations. Clin Rheumatol 2010;29:1211-6.
3. de Menthon M, Lavalley MP, Maldini C, Guillevin L, Mahr A. HLA-B51/B5 and the risk of Behcet's disease: a systematic review and meta-analysis of case-control genetic association studies. Arthritis Rheum 2009;61: 1287-96.
4. Maldini C, Lavalley MP, Cheminant M, de Menthon M, Mahr A. Relationships of HLA-B51 or B5 genotype with Behcet's disease clinical characteristics: systematic review and meta-analyses of observational studies. Rheumatology 2012;51:887-900.
5. Bang DS, Oh SH, Lee KH, Lee ES, Lee SN. Influence of sex on patients with Behcet's disease in Korea. J Korean Med Sci 2003;18:231-5.
6. Davatchi F, Shahram F, Chams H et al. The influence of gender on the severity and the outcome of ocular lesions in Behcet's disease. Adv Exp Med Biol 2003;528:67-71.
7. Davatchi F, Shahram F, Chams-Davatchi C et al. Behcet's disease: is there a gender influence on clinical manifestations? Int J Rheum Dis 2012;15:306-14.
8. Tursen U, Gurler A, Boyvat A. Evaluation of clinical findings according to sex in 2313 Turkish patients with Behcet's disease. Int J Dermatol 2003;42:346-51.
9. Altenburg A, Mahr A, Maldini C et al. Epidemiology and clinical aspects of Adamantiades-Behcet disease in Germany. Current data [in German]. Ophthalmologe 2012; 109:531-41.
10. Davatchi F, Assaad-Khalil S, Calamia KT et al. The International Criteria for Behcet's Disease (ICBD): a collaborative study of 27 countries on the sensitivity and specificity of the new criteria. J Eur Acad Dermatol Venereol 2014;28:338-47.
11. DerSimonian R, Laird N. Meta-analysis in clinical trials. Control Clin Trials 1986;7:177-88.
12. Higgins JP, Thompson SG. Quantifying heterogeneity in a meta-analysis. Stat Med 2002;21:1539-58.
13. Egger M, Davey Smith G, Schneider M, Minder C. Bias in meta-analysis detected by a simple, graphical test. BMJ 1997;315:629-34.
14. Begg CB, Mazumdar M. Operating characteristics of a rank correlation test for publication bias. Biometrics 1994; 50:1088-101.
15. Moher D, Liberati A, Tetzlaff J, Altman DG. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Ann Intern Med 2009;151:264-9, W64.
16. Geri G, Wechsler B, Thi Huong DL et al. Spectrum of cardiac lesions in Behcet disease: a series of 52 patients and review of the literature. Medicine 2012;91: 25-34.
17. al-Dalaan AN, Al Balaa SR, El Ramahi K et al. Behcet's disease in Saudi Arabia. J Rheumatol 1994;21:658-61.
18. B'Chir Hamzaoui S, Harmel A, Bouslama K et al. Behcet's disease in Tunisia. Clinical study of 519 cases [in French]. Rev Med Interne 2006;27:742-50.
19. Alli N, Gur G, Yalcin B, Hayran M. Patient characteristics in Behcet disease: a retrospective analysis of 213 Turkish patients during 2001-4. Am J Clin Dermatol 2009;10: 411-8.
20. Alpsoy E, Donmez L, Onder M et al. Clinical features and natural course of Behcet's disease in 661 cases: a multicentre study. Br J Dermatol 2007;157:901-6.
21. Ames PR, Steuer A, Pap A, Denman AM. Thrombosis in Behcet's disease: a retrospective survey from a single UK centre. Rheumatology 2001;40:652-5.
22. Arida A, Vaiopoulos G, Markomichelakis N, Kaklamanis P, Sfikakis PP. Are clusters of patients with distinct clinical expression present in Behcet's disease? Clin Exp Rheumatol 2009;27:S48-51.
23. Calka O, Akdeniz N, Metin A, Sayarlioglu H. Profile of Behcet's disease at Van and vicinity. Eur J Gen Med 2005; 2:43-6.
24. Chung YM, Liu JH, Tsi ST. Behcet's disease in Taiwan-a review of 53 cases. Jpn J Ophthalmol 1986;30:318-23.
25. Georgiades G, Sinakos Z, Frangoulis C et al. Adamantiades-Behcet syndrome. Current concepts [in French]. Bull Mem Soc Fr Ophtalmol 1976;88: 285-98.
26. Ideguchi H, Suda A, Takeno M et al. Behcet disease: evolution of clinical manifestations. Medicine 2011;90: 125-32.
27. Kotulska A, Kucharz EJ, Kopec M. Behcet's disease in Poland. Clin Rheumatol 2005;24:667-8.
28. Krause I, Yankevich A, Fraser A et al. Prevalence and clinical aspects of Behcet's disease in the north of Israel. Clin Rheumatol 2007;26:555-60.
29. Kural-Seyahi E, Fresko I, Seyahi N et al. The long-term mortality and morbidity of Behcet syndrome: a 2-decade outcome survey of 387 patients followed at a dedicated center. Medicine 2003;82:60-76.
30. Masuda K, Inaba G, Mizushima H, Yaoita H. A nationwide survey of Behcet's disease in Japan. II. Clinical survey. Jpn J Ophthalmol 1975;19:278-85.
31. Mousa AM, Marafie AA, Rifai KM. Behcet's disease in Kuwait, Arabia. A report of 29 cases and a review. Scand J Rheumatol 1986;15:310-32.
32. Nakamura S. Studies of Behcet's disease: a report of the Collaborative Study Group [in Japanese]. Jpn J Natl Med Serv 1973;27:824-30.
33. Ricart JM, Todoli J, Vilata JJ et al. Behcet disease: study of 74 patients [in Spanish]. Med Clin 2006;127:496-9.
34. Sarica R, Azizlerli G, Kose A et al. Juvenile Behcet's disease among 1784 Turkish Behcet's patients. Int J Dermatol 1996;35:109-11.
35. Shang Y, Han S, Li J et al. The clinical feature of Behcet's disease in Northeastern China. Yonsei Med J 2009;50: 630-6.
36. Sharquie KE, Al-Rawi Z, Hatem A, Al-Araji A. The influence of age of onset and patient's sex on the prevalence of clinical manifestations of Behcet's disease in Iraqi patients. Ann Saudi Med 2002;22:239-41.
37. Taniguchi Y, Harada K, Fujita S. Behcet's disease in the Kagoshima district [in Japanese]. Folia Ophthal Jap 1973; 24:990-4.
38. Tunc R, Keyman E, Melikoglu M, Fresko I, Yazici H. Target organ associations in Turkish patients with Behcet's disease: a cross sectional study by exploratory factor analysis. J Rheumatol 2002;29:2393-6.
39. Vaiopoulos G, Konstantopoulou P, Evangelatos N, Kaklamanis P. The spectrum of mucocutaneous manifestations in Adamantiades-Behcet's disease in Greece. J Eur Acad Dermatol Venereol 2011;24:434-8.
40. Wechsler B, Thi Huong DL, Massin I et al. Behcet's disease in France. Apropos of 60 autochtonous subjects [in French]. Ann Med Interne 1988;139:315-9.
41. Wurmann P, Diaz G, Sabugo F et al. [Retrospective review of 44 Chilean patients with Behcet disease]. Rev Med Chil 2009;137:1333-40.
42. Yazici H, Tuzun Y, Pazarli H et al. Influence of age of onset and patient's sex on the prevalence and severity of manifestations of Behcet's syndrome. Ann Rheum Dis 1984;43:783-9.
43. Yurdakul S, Mat C, Tuzun Y et al. A double-blind trial of colchicine in Behcet's syndrome. Arthritis Rheum 2001;44: 2686-92.
44. al-Aboosi MM, Al Salem M, Saadeh A et al. Behcet's disease: clinical study of Jordanian patients. Int J Dermatol 1996;35:623-5.
45. Azizlerli G, Kose AA, Sarica R et al. Prevalence of Behcet's disease in Istanbul, Turkey. Int J Dermatol 2003;42:803-6.
46. Barra C, Belfort R Jr, Abreu MT et al. Behcet's disease in Brazil-a review of 49 cases with emphasis on ophthalmic manifestations. Jpn J Ophthalmol 1991;35: 339-46.
47. Chamberlain MA. Behcet's syndrome in 32 patients in Yorkshire. Ann Rheum Dis 1977;36:491-99.
48. Dilsen N, Konice M, Aral O et al. Risk factors for vital organ involvement in Behcet's disease. In: Godeau P, Wechsler B, eds. Behcet's Disease. Amsterdam: Elsevier Science, 1993:165-169.
49. Eldem B, Onur C, Ozen S. Clinical features of pediatric Behcet's disease. J Pediatr Ophthalmol Strabismus 1998; 35:159-61.
50. Filali-Ansary N, Tazi-Mezalek Z, Mohattane A et al. Behcet disease: 162 cases [in French]. Ann Med Interne 1999;150: 178-88.
51. Fujikawa S, Suemitsu T. Behcet disease in children: a nationwide retrospective survey in Japan. Acta Paediatr Jpn 1997;39:285-9.
52. Geng L, Ohno S, Wang YH, Higuchi M. Clinical observations on Behcet's disease in Tianjin, China. Jpn J Ophthalmol 1985;29:310-4.
53. Hamdan A, Mansour W, Uthman I et al. Behcet's disease in Lebanon: clinical profile, severity and two-decade comparison. Clin Rheumatol 2006;25:364-7.
54. Kang SJ, Kim HB. Behcet's disease in Korea [in Korean]. J Korean Ophthalmol Soc 1992;33:332-41.
55. Koc Y, Gullu I, Akpek G et al. Vascular involvement in Behcet's disease. J Rheumatol 1992;19:402-10.
56. Kone-Paut I, Yurdakul S, Bahabri SA et al. Clinical features of Behcet's disease in children: an international collaborative study of 86 cases. J Pediatr 1998;132: 721-5.
57. Lee J. Statistical study of Behcet's syndrome [in Korean]. J Korean Ophthalmol Soc 1979;20:164-74.
58. Liu XY, Li SG, Shi GY. Comparative study on male and female patients with Behcet's disease [in Chinese]. Chin J Rheumatol 2000;4:82-4.
59. Mangelsdorf HC, White WL, Jorizzo JL. Behcet's disease. Report of twenty-five patients from the United States with prominent mucocutaneous involvement. J Am Acad Dermatol 1996;34:745-50.
60. Mok CC, Cheung TC, Ho CT et al. Behcet's disease in southern Chinese patients. J Rheumatol 2002;29: 1689-93.
61. Oshima Y, Shimizu T, Yokohari R et al. Clinical studies on Behcet's syndrome. Ann Rheum Dis 1963;22: 36-45.
62. Prokaeva T, Madanat W, Yermakova N, Alekberova Z. Sex dimorphism of Behcet's disease. In: Godeau P, Wechsler., eds. Behcet's Disease. Amsterdam: Elsevier Science, 1993:219-21.
63. Seaman G, Pearce RA. Disease manifestation in a population drawn from the UK Behcet's syndrome society. In: Hamza M, ed. Behcet's Disease. Tunis, Tunisia: Pub Adhoua, 1997:196-9.
64. Uziel Y, Brik R, Padeh S et al. Juvenile Behcet's disease in Israel. The Pediatric Rheumatology Study Group of Israel. Clin Exp Rheumatol 1998;16:502-5.
65. Yu YX, Gong Y. Clinical characteristics of male patients with Behcet's disease [in Chinese. Chin J Mod Med 2004; 14:138-42.
66. Zierhut M, Saal J, Pleyer U et al. Behcet's disease: epidemiology and eye manifestations in German and Mediterranian patients. Ger J Ophthalmol 1995;4:246-51.
67. White RH. The epidemiology of venous thromboembolism. Circulation 2003;107:I4-8.
68. Gurgun C, Ercan E, Ceyhan C et al. Cardiovascular involvement in Behcet's disease. Jpn Heart J 2002;43:389-98.
69. Giacomoni PU, Mammone T, Teri M. Gender-linked differences in human skin. J Dermatol Sci 2009;55:144-9.
70. Yavuz S, Ozilhan G, Elbir Y et al. Activation of neutrophils by testosterone in Behcet's disease. Clin Exp Rheumatol 2007;25(Suppl 45):S46-51.
71. Garcia-Porrua C, Gonzalez-Gay MA, Vazquez-Caruncho M et al. Erythema nodosum: etiologic and predictive factors in a defined population. Arthritis Rheum 2000;43:584-92.
72. Mert A, Kumbasar H, Ozaras R et al. Erythema nodosum: an evaluation of 100 cases. Clin Exp Rheumatol 2007;25: 563-70.
73. Saadoun D, Wechsler B, Desseaux K et al. Mortality in Behcet's disease. Arthritis Rheum 2010;62:2806-12.
74. Kitaichi N, Miyazaki A, Iwata D et al. Ocular features of Behcet's disease: an international collaborative study. Br J Ophthalmol 2007;91:1579-82.
75. Zouboulis CC. Epidemiology of Adamantiades-Behcet's disease. Ann Med Interne 1999;150:488-98.