Deregulation of sertoli and leydig cells function in patients with klinefelter syndrome as evidenced by testis transcriptome analysis

BMC Genomics

Volumn 16, Issue 1, 2015, Pages

  D'Aurora, Marco ^a,b   Ferlin, Alberto ^c   Di Nicola, Marta ^a   Garolla, Andrea ^c   De Toni, Luca ^c   Franchi, Sara ^a,b   Palka, Giandomenico ^a   Foresta, Carlo ^c   Stuppia, Liborio ^a,b   Gatta, Valentina ^a,b  

^a UNIVERSITY OF CHIETI   (Italy)

^b Functional Genetics Unit   (Italy)

^c UNIVERSITY OF PADOVA   (Italy)

Author keywords

Klinefelter Syndrome; Leydig cells; Male infertility; Microarray; Sertoli cells; Testis transcriptome

Indexed keywords

TRANSCRIPTOME;

ADULT; ARTICLE; BLOOD TESTIS BARRIER; CELL DAMAGE; CELL DEATH; CELL FUNCTION; CLINICAL ARTICLE; CONTROLLED STUDY; DNA MODIFICATION; DOWN REGULATION; FUNCTIONAL ASSESSMENT; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; HUMAN TISSUE; INFLAMMATION; KLINEFELTER SYNDROME; LEYDIG CELL; LIPID METABOLISM; MALE; RNA ANALYSIS; RNA TRANSCRIPTION; SERTOLI CELL; SPERMATOGENESIS; STEROIDOGENESIS; TESTIS BIOPSY; UPREGULATION; CLUSTER ANALYSIS; GENE REGULATORY NETWORK; GENETICS; INFERTILITY, MALE; KARYOTYPE; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; SEX CHROMOSOME; SIGNAL TRANSDUCTION; TESTIS;

ADULT; BLOOD-TESTIS BARRIER; CLUSTER ANALYSIS; DOWN-REGULATION; GENE REGULATORY NETWORKS; HUMANS; INFERTILITY, MALE; KARYOTYPE; KLINEFELTER SYNDROME; LEYDIG CELLS; LIPID METABOLISM; MALE; SERTOLI CELLS; SEX CHROMOSOMES; SIGNAL TRANSDUCTION; SPERMATOGENESIS; TESTIS; TRANSCRIPTOME; UP-REGULATION;

EID: 84928745678     PISSN: None     EISSN: 14712164     Source Type: Journal    
DOI: 10.1186/s12864-015-1356-0     Document Type: Article

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