-
1
-
-
38649124003
-
Epigenetic targets of HDAC inhibition in neurodegenerative and psychiatric disorders
-
Abel T., Zukin R.S. Epigenetic targets of HDAC inhibition in neurodegenerative and psychiatric disorders. Curr Opin Pharmacol 2008, 8:57-64.
-
(2008)
Curr Opin Pharmacol
, vol.8
, pp. 57-64
-
-
Abel, T.1
Zukin, R.S.2
-
2
-
-
84911394488
-
Epigenetic signaling in psychiatric disorders: stress and depression
-
Bagot R.C., Labonte B., Peña C.J., Nestler E.J. Epigenetic signaling in psychiatric disorders: stress and depression. Dialogues Clin Neurosci 2014, 16:281-295.
-
(2014)
Dialogues Clin Neurosci
, vol.16
, pp. 281-295
-
-
Bagot, R.C.1
Labonte, B.2
Peña, C.J.3
Nestler, E.J.4
-
3
-
-
32444451651
-
Essential role of BDNF in the mesolimbic dopamine pathway in social defeat stress
-
Berton O., McClung C.A., DiLeone R.J., Krishnan V., Russo S., Graham D., Tsankova N.M., Bolanos C.A., Rios M., Monteggia L.M., Self D.W., Nestler E.J. Essential role of BDNF in the mesolimbic dopamine pathway in social defeat stress. Science 2006, 311:864-868.
-
(2006)
Science
, vol.311
, pp. 864-868
-
-
Berton, O.1
McClung, C.A.2
DiLeone, R.J.3
Krishnan, V.4
Russo, S.5
Graham, D.6
Tsankova, N.M.7
Bolanos, C.A.8
Rios, M.9
Monteggia, L.M.10
Self, D.W.11
Nestler, E.J.12
-
4
-
-
57649239938
-
Decoding the epigenetic language of neuronal plasticity
-
Borrelli E., Nestler E.J., Allis C.D., Sassone-Corsi P. Decoding the epigenetic language of neuronal plasticity. Neuron 2008, 60:961-974.
-
(2008)
Neuron
, vol.60
, pp. 961-974
-
-
Borrelli, E.1
Nestler, E.J.2
Allis, C.D.3
Sassone-Corsi, P.4
-
6
-
-
70349085803
-
Antidepressant actions of HDAC inhibitors
-
Covington H.E., Maze I., LaPlant Q.C., Vialou V.F., Yoshinori O.N., Berton O., Fass D.M., Renthal W., Rush A.J., Wu E.Y., Ghose S., Krishnan V., Russo S.J., Tamminga C., Haggarty S.J., Nestler E.J. Antidepressant actions of HDAC inhibitors. J Neurosci 2009, 29:11451-11460.
-
(2009)
J Neurosci
, vol.29
, pp. 11451-11460
-
-
Covington, H.E.1
Maze, I.2
LaPlant, Q.C.3
Vialou, V.F.4
Yoshinori, O.N.5
Berton, O.6
Fass, D.M.7
Renthal, W.8
Rush, A.J.9
Wu, E.Y.10
Ghose, S.11
Krishnan, V.12
Russo, S.J.13
Tamminga, C.14
Haggarty, S.J.15
Nestler, E.J.16
-
7
-
-
79952902253
-
Hippocampal-dependent antidepressant-like activity of histone deacetylase inhibition
-
Covington H.E., Vialou V.F., Laplant Q., Ohnishi Y.N., Nestler E.J. Hippocampal-dependent antidepressant-like activity of histone deacetylase inhibition. Neurosci Lett 2011, 493:122-126.
-
(2011)
Neurosci Lett
, vol.493
, pp. 122-126
-
-
Covington, H.E.1
Vialou, V.F.2
Laplant, Q.3
Ohnishi, Y.N.4
Nestler, E.J.5
-
8
-
-
84898867072
-
Pathophysiology of depression and innovative treatments: remodeling glutamatergic synaptic connections
-
Duman R.S. Pathophysiology of depression and innovative treatments: remodeling glutamatergic synaptic connections. Dialogues Clin Neurosci 2014, 16:11-27.
-
(2014)
Dialogues Clin Neurosci
, vol.16
, pp. 11-27
-
-
Duman, R.S.1
-
9
-
-
33745208951
-
A neurotrophic model for stress-related mood disorders
-
Duman R.S., Monteggia L.M. A neurotrophic model for stress-related mood disorders. Biol Psychiatry 2006, 59:1116-1127.
-
(2006)
Biol Psychiatry
, vol.59
, pp. 1116-1127
-
-
Duman, R.S.1
Monteggia, L.M.2
-
10
-
-
84875168737
-
Toxicological and metabolic considerations for histone deacetylase inhibitors
-
Fraczek J., Vanhaecke T., Rogiers V. Toxicological and metabolic considerations for histone deacetylase inhibitors. Expert Opin Drug Metab Toxicol 2013, 9:441-457.
-
(2013)
Expert Opin Drug Metab Toxicol
, vol.9
, pp. 441-457
-
-
Fraczek, J.1
Vanhaecke, T.2
Rogiers, V.3
-
11
-
-
84872601036
-
Histone acetylation: molecular mnemonics on the chromatin
-
Graff J., Tsai L.H. Histone acetylation: molecular mnemonics on the chromatin. Nat Rev Neurosci 2013, 14:97-111.
-
(2013)
Nat Rev Neurosci
, vol.14
, pp. 97-111
-
-
Graff, J.1
Tsai, L.H.2
-
12
-
-
57749170458
-
The many roles of histone deacetylases in development and physiology: implications for disease and therapy
-
Haberland M., Montgomery R.L., Olson E.N. The many roles of histone deacetylases in development and physiology: implications for disease and therapy. Nat Rev Genet 2009, 10:32-42.
-
(2009)
Nat Rev Genet
, vol.10
, pp. 32-42
-
-
Haberland, M.1
Montgomery, R.L.2
Olson, E.N.3
-
13
-
-
78651484732
-
Repeated social defeat selectively increases δFosB expression and histone H3 acetylation in the infralimbic medial prefrontal cortex
-
Hinwood M., Tynan R.J., Day T.A., Walker F.R. Repeated social defeat selectively increases δFosB expression and histone H3 acetylation in the infralimbic medial prefrontal cortex. Cereb Cortex 2011, 21:262-271.
-
(2011)
Cereb Cortex
, vol.21
, pp. 262-271
-
-
Hinwood, M.1
Tynan, R.J.2
Day, T.A.3
Walker, F.R.4
-
14
-
-
77955581894
-
The effects of repeated social defeat on long-term depressive-like behavior and short-term histone modifications in the hippocampus in male Sprague-Dawley rats
-
Hollis F., Wang H., Dietz D., Gunjan A., Kabbaj M. The effects of repeated social defeat on long-term depressive-like behavior and short-term histone modifications in the hippocampus in male Sprague-Dawley rats. Psychopharmacology 2010, 211:69-77.
-
(2010)
Psychopharmacology
, vol.211
, pp. 69-77
-
-
Hollis, F.1
Wang, H.2
Dietz, D.3
Gunjan, A.4
Kabbaj, M.5
-
15
-
-
79952697546
-
Individual differences in the effect of social defeat on anhedonia and histone acetylation in the rat hippocampus
-
Hollis F., Duclot F., Gunjan A., Kabbaj M. Individual differences in the effect of social defeat on anhedonia and histone acetylation in the rat hippocampus. Horm Behav 2011, 59:331-337.
-
(2011)
Horm Behav
, vol.59
, pp. 331-337
-
-
Hollis, F.1
Duclot, F.2
Gunjan, A.3
Kabbaj, M.4
-
16
-
-
77952170915
-
Histone deacetylase inhibitor, MS-275, exhibits poor brain penetration: PK studies of [C]MS-275 using Positron Emission Tomography
-
Hooker J.M., Kim S.W., Alexoff D., Xu Y., Shea C., Reid A., Volkow N., Fowler J.S. Histone deacetylase inhibitor, MS-275, exhibits poor brain penetration: PK studies of [C]MS-275 using Positron Emission Tomography. ACS Chem Neurosci 2010, 1:65-73.
-
(2010)
ACS Chem Neurosci
, vol.1
, pp. 65-73
-
-
Hooker, J.M.1
Kim, S.W.2
Alexoff, D.3
Xu, Y.4
Shea, C.5
Reid, A.6
Volkow, N.7
Fowler, J.S.8
-
17
-
-
84875669092
-
Class I HDAC inhibition blocks cocaine-induced plasticity by targeted changes in histone methylation
-
Kennedy P.J., Feng J., Robison A.J., Maze I., Badimon A., Mouzon E., Chaudhury D., Damez-Werno D.M., Haggarty S.J., Han M.H., Bassel-Duby R., Olson E.N., Nestler E.J. Class I HDAC inhibition blocks cocaine-induced plasticity by targeted changes in histone methylation. Nat Neurosci 2013, 16:434-440.
-
(2013)
Nat Neurosci
, vol.16
, pp. 434-440
-
-
Kennedy, P.J.1
Feng, J.2
Robison, A.J.3
Maze, I.4
Badimon, A.5
Mouzon, E.6
Chaudhury, D.7
Damez-Werno, D.M.8
Haggarty, S.J.9
Han, M.H.10
Bassel-Duby, R.11
Olson, E.N.12
Nestler, E.J.13
-
18
-
-
84895863341
-
Social defeat induces changes in histone acetylation and expression of histone modifying enzymes in the ventral hippocampus, prefrontal cortex, and dorsal raphe nucleus
-
Kenworthy C.A., Sengupta A., Luz S.M., Ver Hoeve E.S., Meda K., Bhatnagar S., Abel T. Social defeat induces changes in histone acetylation and expression of histone modifying enzymes in the ventral hippocampus, prefrontal cortex, and dorsal raphe nucleus. Neuroscience 2013, 264:88-98.
-
(2013)
Neuroscience
, vol.264
, pp. 88-98
-
-
Kenworthy, C.A.1
Sengupta, A.2
Luz, S.M.3
Ver Hoeve, E.S.4
Meda, K.5
Bhatnagar, S.6
Abel, T.7
-
19
-
-
37849019672
-
Determination of the class and isoform selectivity of small-molecule histone deacetylase inhibitors
-
Khan N., Jeffers M., Kumar S., Hackett C., Boldog F., Khramtsov N., Qian X., Mills E., Berghs S.C., Carey N., Finn P.W., Collins L.S., Tumber A., Ritchie J.W., Jensen P.B., Lichenstein H.S., Sehested M. Determination of the class and isoform selectivity of small-molecule histone deacetylase inhibitors. Biochem J 2009, 409:581-589.
-
(2009)
Biochem J
, vol.409
, pp. 581-589
-
-
Khan, N.1
Jeffers, M.2
Kumar, S.3
Hackett, C.4
Boldog, F.5
Khramtsov, N.6
Qian, X.7
Mills, E.8
Berghs, S.C.9
Carey, N.10
Finn, P.W.11
Collins, L.S.12
Tumber, A.13
Ritchie, J.W.14
Jensen, P.B.15
Lichenstein, H.S.16
Sehested, M.17
-
20
-
-
35348832393
-
Molecular adaptations underlying susceptibility and resistance to social defeat in brain reward regions
-
Krishnan V., Han M.H., Graham D.L., Berton O., Renthal W., Russo S.J., Laplant Q., Graham A., Lutter M., Lagace D.C., Ghose S., Reister R., Tannous P., Green T.A., Neve R.L., Chakravarty S., Kumar A., Eisch A.J., Self D.W., Lee F.S., Tamminga C.A., Cooper D.C., Gershenfeld H.K., Nestler E.J. Molecular adaptations underlying susceptibility and resistance to social defeat in brain reward regions. Cell 2007, 131:391-404.
-
(2007)
Cell
, vol.131
, pp. 391-404
-
-
Krishnan, V.1
Han, M.H.2
Graham, D.L.3
Berton, O.4
Renthal, W.5
Russo, S.J.6
Laplant, Q.7
Graham, A.8
Lutter, M.9
Lagace, D.C.10
Ghose, S.11
Reister, R.12
Tannous, P.13
Green, T.A.14
Neve, R.L.15
Chakravarty, S.16
Kumar, A.17
Eisch, A.J.18
Self, D.W.19
Lee, F.S.20
Tamminga, C.A.21
Cooper, D.C.22
Gershenfeld, H.K.23
Nestler, E.J.24
more..
-
21
-
-
84883182497
-
The brain reward circuitry in mood disorders
-
Russo S.J., Nestler E.J. The brain reward circuitry in mood disorders. Nat Rev Neurosci 2013, 14:609-625.
-
(2013)
Nat Rev Neurosci
, vol.14
, pp. 609-625
-
-
Russo, S.J.1
Nestler, E.J.2
-
22
-
-
34250161829
-
Antidepressant-like effects of the histone deacetylase inhibitor, sodium butyrate, in the mouse
-
Schroeder F.A., Lin C.L., Crusio W.E., Akbarian S. Antidepressant-like effects of the histone deacetylase inhibitor, sodium butyrate, in the mouse. Biol Psychiatry 2007, 62:55-64.
-
(2007)
Biol Psychiatry
, vol.62
, pp. 55-64
-
-
Schroeder, F.A.1
Lin, C.L.2
Crusio, W.E.3
Akbarian, S.4
-
23
-
-
84928724800
-
Multimodal approaches to define network oscillations in depression
-
press, PMID:25681871
-
Smart O.L., Tiruvadi V.R., Mayberg H.S. multimodal approaches to define network oscillations in depression. Biol Psychiatry 2015, in press, PMID:25681871.
-
(2015)
Biol Psychiatry
-
-
Smart, O.L.1
Tiruvadi, V.R.2
Mayberg, H.S.3
-
24
-
-
0034610814
-
The language of covalent histone modifications
-
Strahl B.D., Allis C.D. The language of covalent histone modifications. Nature 2000, 403:41-45.
-
(2000)
Nature
, vol.403
, pp. 41-45
-
-
Strahl, B.D.1
Allis, C.D.2
-
25
-
-
84869096094
-
Epigenetics of the depressed brain: role of histone acetylation and methylation
-
Sun H.S., Kennedy P.J., Nestler E.J. Epigenetics of the depressed brain: role of histone acetylation and methylation. Neuropsychopharmacol Rev 2013, 38:124-137.
-
(2013)
Neuropsychopharmacol Rev
, vol.38
, pp. 124-137
-
-
Sun, H.S.1
Kennedy, P.J.2
Nestler, E.J.3
-
26
-
-
33645357786
-
Sustained hippocampal chromatin regulation in hippocampus in a mouse model of depression and antidepressant action
-
Tsankova N.M., Berton O., Renthal W., Kumar A., Neve R.L., Nestler E.J. Sustained hippocampal chromatin regulation in hippocampus in a mouse model of depression and antidepressant action. Nat Neurosci 2006, 9:519-525.
-
(2006)
Nat Neurosci
, vol.9
, pp. 519-525
-
-
Tsankova, N.M.1
Berton, O.2
Renthal, W.3
Kumar, A.4
Neve, R.L.5
Nestler, E.J.6
-
27
-
-
77952888646
-
DeltaFosB in brain reward circuits mediates resilience to stress and antidepressant responses
-
Vialou V., Robison A.J., Laplant Q.C., Covington H.E., Dietz D.M., Ohnishi Y.N., Mouzon E., Rush A.J., Watts E.L., Wallace D.L., Iñiguez S.D., Ohnishi Y.H., Steiner M.A., Warren B.L., Krishnan V., Bolaños C.A., Neve R.L., Ghose S., Berton O., Tamminga C.A., Nestler E.J. DeltaFosB in brain reward circuits mediates resilience to stress and antidepressant responses. Nat Neurosci 2010, 13:745-752.
-
(2010)
Nat Neurosci
, vol.13
, pp. 745-752
-
-
Vialou, V.1
Robison, A.J.2
Laplant, Q.C.3
Covington, H.E.4
Dietz, D.M.5
Ohnishi, Y.N.6
Mouzon, E.7
Rush, A.J.8
Watts, E.L.9
Wallace, D.L.10
Iñiguez, S.D.11
Ohnishi, Y.H.12
Steiner, M.A.13
Warren, B.L.14
Krishnan, V.15
Bolaños, C.A.16
Neve, R.L.17
Ghose, S.18
Berton, O.19
Tamminga, C.A.20
Nestler, E.J.21
more..
-
28
-
-
84872241553
-
Epigenetic mechanisms of depression and antidepressant action
-
Vialou V., Feng J., Robison A.J., Nestler E.J. Epigenetic mechanisms of depression and antidepressant action. Annu Rev Pharmacol Toxicol 2013, 53:59-87.
-
(2013)
Annu Rev Pharmacol Toxicol
, vol.53
, pp. 59-87
-
-
Vialou, V.1
Feng, J.2
Robison, A.J.3
Nestler, E.J.4
-
29
-
-
84896754936
-
Prefrontal cortical circuit for depression- and anxiety-related behaviors mediated by cholecystokinin: role of δFosB
-
Vialou V., Bagot R.C., Cahill M.E., Ferguson D., Robison A.J., Dietz D.M., Fallon B., Mazei-Robison M., Ku S.M., Harrigan E., Winstanley C.A., Joshi T., Feng J., Berton O., Nestler E.J. Prefrontal cortical circuit for depression- and anxiety-related behaviors mediated by cholecystokinin: role of δFosB. J Neurosci 2014, 34:3878-3887.
-
(2014)
J Neurosci
, vol.34
, pp. 3878-3887
-
-
Vialou, V.1
Bagot, R.C.2
Cahill, M.E.3
Ferguson, D.4
Robison, A.J.5
Dietz, D.M.6
Fallon, B.7
Mazei-Robison, M.8
Ku, S.M.9
Harrigan, E.10
Winstanley, C.A.11
Joshi, T.12
Feng, J.13
Berton, O.14
Nestler, E.J.15
-
30
-
-
57549099873
-
Antidepressant-like effects of sodium butyrate in combination with estrogen in rat forced swimming test: involvement of 5-HT(1A) receptors
-
Zhu H., Huang Q., Xu H., Niu L., Zhou J.N. Antidepressant-like effects of sodium butyrate in combination with estrogen in rat forced swimming test: involvement of 5-HT(1A) receptors. Behav Brain Res 2009, 196:200-206.
-
(2009)
Behav Brain Res
, vol.196
, pp. 200-206
-
-
Zhu, H.1
Huang, Q.2
Xu, H.3
Niu, L.4
Zhou, J.N.5
|