The gametocytocidal efficacy of primaquine in malaria asymptomatic carriers treated with dihydroartemisinin-piperaquine in The Gambia (PRINOGAM): Study protocol for a randomised controlled trial

Trials

Volumn 16, Issue 1, 2015, Pages

  Okebe, Joseph ^a   Bousema, Teun ^b   Affara, Muna ^a   DiTanna, GianLuca ^b   Eziefula, Alice C ^b   Jawara, Musa ^a   Nwakanma, Davis ^a   Amambua Ngwa, Alfred ^a   geertruyden, Jean Pierre ^c   Drakeley, Chris ^b   D'Alessandro, Umberto ^a,b,d  

^a Medical Research Council Unit The Gambia   (Gambia)

^b LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^c UNIVERSITY OF ANTWERP   (Belgium)

^d INSTITUTE OF TROPICAL MEDICINE   (Belgium)

Author keywords

Asymptomatic infection; Efficacy; Elimination; Gametocyte; Malaria; Plasmodium falciparum; Primaquine; Safety

Indexed keywords

DIHYDROARTEMISININ PLUS PIPERAQUINE; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; PRIMAQUINE; ANTIMALARIAL AGENT; ARTEMISININ DERIVATIVE; DIHYDROARTEMISININ; DRUG COMBINATION; PIPERAQUINE; QUINOLINE DERIVATIVE;

ARTICLE; ASYMPTOMATIC INFECTION; CHILD; CLINICAL EFFECTIVENESS; CLINICAL PROTOCOL; COMPARATIVE EFFECTIVENESS; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG EFFICACY; FEMALE; FOLLOW UP; GAMBIA; GAMETOCYTE; HEMOLYSIS; HUMAN; MAJOR CLINICAL STUDY; MALARIA; MALE; MOSQUITO; NUCLEIC ACID SEQUENCE BASED AMPLIFICATION; OUTCOME ASSESSMENT; PARASITE PREVALENCE; PARASITE TRANSMISSION; PLASMODIUM FALCIPARUM; RANDOMIZED CONTROLLED TRIAL; SCREENING TEST; DRUG COMBINATION; DRUG EFFECTS; SAMPLE SIZE; STATISTICAL ANALYSIS;

ANTIMALARIALS; ARTEMISININS; CLINICAL PROTOCOLS; DATA INTERPRETATION, STATISTICAL; DRUG COMBINATIONS; HUMANS; PLASMODIUM FALCIPARUM; PRIMAQUINE; QUINOLINES; SAMPLE SIZE;

EID: 84928726495     PISSN: None     EISSN: 17456215     Source Type: Journal    
DOI: 10.1186/s13063-015-0597-1     Document Type: Article

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