메뉴 건너뛰기




Volumn 13, Issue 1, 2015, Pages

A general review of major global coagulation assays: Thrombelastography, thrombin generation test and clot waveform analysis

Author keywords

Global coagulation assays; Hemophilia; Hemorrhage; Thrombosis

Indexed keywords

BLEEDING TENDENCY; BLOOD CLOT LYSIS; BLOOD CLOTTING TEST; CLOT WAVEFORM ANALYSIS; DISSEMINATED INTRAVASCULAR CLOTTING; FIBRIN CLOT; HEMATOLOGICAL PROCEDURE; HUMAN; PARTIAL THROMBOPLASTIN TIME; REVIEW; THROMBIN TIME; THROMBOCYTE DYSFUNCTION; THROMBOCYTE POOR PLASMA; THROMBOCYTE RICH PLASMA; THROMBOELASTOGRAPH; THROMBOELASTOGRAPHY; THROMBOELASTOMETRY; THROMBOPHILIA; VISCOELASTICITY;

EID: 84928725356     PISSN: None     EISSN: 14779560     Source Type: Journal    
DOI: 10.1186/1477-9560-13-1     Document Type: Review
Times cited : (158)

References (56)
  • 1
    • 49349107361 scopus 로고    scopus 로고
    • The top 10 causes of death
    • Assesed 2015 from
    • WHO: The top 10 causes of death. 2012. Assesed 2015 from [ http://www.who.int.mediacentre/factsheets/fs310/en/ ]
    • (2012)
  • 2
    • 29244431984 scopus 로고    scopus 로고
    • To bleed or not to bleed? Is that the question for the PTT?
    • Kitchens CS: To bleed or not to bleed? Is that the question for the PTT? J Thromb Haemost 2005, 3:2607-2611. 10.1111/j.1538-7836.2005.01552.x.
    • (2005) J Thromb Haemost , vol.3 , pp. 2607-2611
    • Kitchens, C.S.1
  • 3
    • 26944494224 scopus 로고    scopus 로고
    • Paucity of studies to support that abnormal coagulation test results predict bleeding in the setting of invasive procedures: an evidence-based review
    • Segal JB, Dzik WH: Paucity of studies to support that abnormal coagulation test results predict bleeding in the setting of invasive procedures: an evidence-based review. Transfusion 2005, 45:1413-1425. 10.1111/j.1537-2995.2005.00546.x.
    • (2005) Transfusion , vol.45 , pp. 1413-1425
    • Segal, J.B.1    Dzik, W.H.2
  • 6
    • 0001495969 scopus 로고
    • Blutgerinnungsstudien mit der Thromboelastographie: einem neuen Untersuchungsverfahren
    • Hartert H: Blutgerinnungsstudien mit der Thromboelastographie: einem neuen Untersuchungsverfahren. Klin Wochenschr 1948, 26:577-583. 10.1007/BF01697545.
    • (1948) Klin Wochenschr , vol.26 , pp. 577-583
    • Hartert, H.1
  • 7
    • 0009549643 scopus 로고
    • A thrombin generation test; the application in haemophilia and thrombocytopenia
    • Macfarlane RG, Biggs R: A thrombin generation test; the application in haemophilia and thrombocytopenia. J Clin Pathol 1953, 6:3-8. 10.1136/jcp.6.1.3.
    • (1953) J Clin Pathol , vol.6 , pp. 3-8
    • Macfarlane, R.G.1    Biggs, R.2
  • 8
    • 84928795850 scopus 로고
    • Die Auswertungen des Thromboelastogramms.
    • Basel-New York: Karger, S.;
    • Holzknecht F: Die Auswertungen des Thromboelastogramms. Basel-New York: Karger, S.; 1962.
    • (1962)
    • Holzknecht, F.1
  • 9
    • 84928812746 scopus 로고    scopus 로고
    • Die Entwicklung der Thromboelastographie ans Messverfahren
    • Book Die Entwicklung der Thromboelastographie ans Messverfahren
    • Strassner H: Die Entwicklung der Thromboelastographie ans Messverfahren. Book Die Entwicklung der Thromboelastographie ans Messverfahren 2002.
    • (2002)
    • Strassner, H.1
  • 12
    • 0023622521 scopus 로고
    • Effects of progressive blood loss on coagulation as measured by thrombelastography
    • Tuman KJ, Spiess BD, McCarthy RJ, Ivankovich AD: Effects of progressive blood loss on coagulation as measured by thrombelastography. Anesth Analg 1987, 66:856-863. 10.1097/00000542-198706000-00039.
    • (1987) Anesth Analg , vol.66 , pp. 856-863
    • Tuman, K.J.1    Spiess, B.D.2    McCarthy, R.J.3    Ivankovich, A.D.4
  • 13
    • 42449112966 scopus 로고    scopus 로고
    • Coagulation monitoring: current techniques and clinical use of viscoelastic point-of-care coagulation devices
    • Ganter MT, Hofer CK: Coagulation monitoring: current techniques and clinical use of viscoelastic point-of-care coagulation devices. Anesth Analg 2008, 106:1366-1375. 10.1213/ane.0b013e318168b367.
    • (2008) Anesth Analg , vol.106 , pp. 1366-1375
    • Ganter, M.T.1    Hofer, C.K.2
  • 14
    • 70749088102 scopus 로고    scopus 로고
    • Correction of coagulation in dilutional coagulopathy: use of kinetic and capacitive coagulation assays to improve hemostasis
    • Schols SE, Heemskerk JW, van Pampus EC: Correction of coagulation in dilutional coagulopathy: use of kinetic and capacitive coagulation assays to improve hemostasis. Transfus Med Rev 2010, 24:44-52. 10.1016/j.tmrv.2009.09.004.
    • (2010) Transfus Med Rev , vol.24 , pp. 44-52
    • Schols, S.E.1    Heemskerk, J.W.2    van Pampus, E.C.3
  • 15
    • 79953280012 scopus 로고    scopus 로고
    • Thrombelastography (TEG) or thromboelastometry (ROTEM) to monitor haemotherapy versus usual care in patients with massive transfusion
    • Afshari A, Wikkelso A, Brok J, Moller AM, Wetterslev J: Thrombelastography (TEG) or thromboelastometry (ROTEM) to monitor haemotherapy versus usual care in patients with massive transfusion. Cochrane Database Syst Rev 2011, 16:CD007871.
    • (2011) Cochrane Database Syst Rev , vol.16 , pp. CD007871
    • Afshari, A.1    Wikkelso, A.2    Brok, J.3    Moller, A.M.4    Wetterslev, J.5
  • 16
    • 58449096376 scopus 로고    scopus 로고
    • Effect of Haemostatic Control Resuscitation on mortality in massively bleeding patients: a before and after study
    • Johansson PI, Stensballe J: Effect of Haemostatic Control Resuscitation on mortality in massively bleeding patients: a before and after study. Vox Sang 2009, 96:111-118. 10.1111/j.1423-0410.2008.01130.x.
    • (2009) Vox Sang , vol.96 , pp. 111-118
    • Johansson, P.I.1    Stensballe, J.2
  • 17
    • 77950681467 scopus 로고    scopus 로고
    • Goal-directed coagulation management of major trauma patients using thromboelastometry (ROTEM)-guided administration of fibrinogen concentrate and prothrombin complex concentrate
    • Schochl H, Nienaber U, Hofer G, Voelckel W, Jambor C, Scharbert G, Kozek-Langenecker S, Solomon C: Goal-directed coagulation management of major trauma patients using thromboelastometry (ROTEM)-guided administration of fibrinogen concentrate and prothrombin complex concentrate. Crit Care 2010, 14:R55. 10.1186/cc8948.
    • (2010) Crit Care , vol.14 , pp. R55
    • Schochl, H.1    Nienaber, U.2    Hofer, G.3    Voelckel, W.4    Jambor, C.5    Scharbert, G.6    Kozek-Langenecker, S.7    Solomon, C.8
  • 18
    • 81855194434 scopus 로고    scopus 로고
    • First-line therapy with coagulation factor concentrates combined with point-of-care coagulation testing is associated with decreased allogeneic blood transfusion in cardiovascular surgery: a retrospective, single-center cohort study
    • Gorlinger K, Dirkmann D, Hanke AA, Kamler M, Kottenberg E, Thielmann M, Jakob H, Peters J: First-line therapy with coagulation factor concentrates combined with point-of-care coagulation testing is associated with decreased allogeneic blood transfusion in cardiovascular surgery: a retrospective, single-center cohort study. Anesthesiology 2011, 115:1179-1191.
    • (2011) Anesthesiology , vol.115 , pp. 1179-1191
    • Gorlinger, K.1    Dirkmann, D.2    Hanke, A.A.3    Kamler, M.4    Kottenberg, E.5    Thielmann, M.6    Jakob, H.7    Peters, J.8
  • 20
    • 84902375752 scopus 로고    scopus 로고
    • Improvements in patient blood management for pediatric craniosynostosis surgery using a ROTEM -assisted strategy - feasibility and costs
    • Haas T, Goobie S, Spielmann N, Weiss M, Schmugge M: Improvements in patient blood management for pediatric craniosynostosis surgery using a ROTEM -assisted strategy - feasibility and costs. Paediatr Anaesth 2014, 24:774-80. 10.1111/pan.12341.
    • (2014) Paediatr Anaesth , vol.24 , pp. 774-780
    • Haas, T.1    Goobie, S.2    Spielmann, N.3    Weiss, M.4    Schmugge, M.5
  • 21
    • 33749048058 scopus 로고    scopus 로고
    • Possibilities and limitations of thrombelastometry/-graphy
    • Lang T, von Depka M: Possibilities and limitations of thrombelastometry/-graphy. Hamostaseologie 2006, 26:S20-S29.
    • (2006) Hamostaseologie , vol.26 , pp. S20-S29
    • Lang, T.1    von Depka, M.2
  • 22
    • 70349568133 scopus 로고    scopus 로고
    • In vitro inhibition of factor XIII retards clot formation, reduces clot firmness, and increases fibrinolytic effects in whole blood
    • Jambor C, Reul V, Schnider TW, Degiacomi P, Metzner H, Korte WC: In vitro inhibition of factor XIII retards clot formation, reduces clot firmness, and increases fibrinolytic effects in whole blood. Anesth Analg 2009, 109:1023-1028. 10.1213/ANE.0b013e3181b5a263.
    • (2009) Anesth Analg , vol.109 , pp. 1023-1028
    • Jambor, C.1    Reul, V.2    Schnider, T.W.3    Degiacomi, P.4    Metzner, H.5    Korte, W.C.6
  • 23
    • 78049281996 scopus 로고    scopus 로고
    • Quality assurance and quality control of thrombelastography and rotational Thromboelastometry: the UK NEQAS for blood coagulation experience
    • Kitchen DP, Kitchen S, Jennings I, Woods T, Walker I: Quality assurance and quality control of thrombelastography and rotational Thromboelastometry: the UK NEQAS for blood coagulation experience. Semin Thromb Hemost 2010, 36:757-763. 10.1055/s-0030-1265292.
    • (2010) Semin Thromb Hemost , vol.36 , pp. 757-763
    • Kitchen, D.P.1    Kitchen, S.2    Jennings, I.3    Woods, T.4    Walker, I.5
  • 27
    • 0005560821 scopus 로고
    • A simple method of studying the generation of thrombin in recalcified plasma; application in the investigation of haemophilia
    • Pitney WR, Dacie JV: A simple method of studying the generation of thrombin in recalcified plasma; application in the investigation of haemophilia. J Clin Pathol 1953, 6:9-14. 10.1136/jcp.6.1.9.
    • (1953) J Clin Pathol , vol.6 , pp. 9-14
    • Pitney, W.R.1    Dacie, J.V.2
  • 28
    • 33751210094 scopus 로고    scopus 로고
    • Thrombin generation, a function test of the haemostatic-thrombotic system
    • Hemker HC, Al Dieri R, De Smedt E, Beguin S: Thrombin generation, a function test of the haemostatic-thrombotic system. Thromb Haemost 2006, 96:553-561.
    • (2006) Thromb Haemost , vol.96 , pp. 553-561
    • Hemker, H.C.1    Al Dieri, R.2    De Smedt, E.3    Beguin, S.4
  • 30
    • 0034970007 scopus 로고    scopus 로고
    • The role of factor XI in thrombin generation induced by low concentrations of tissue factor
    • Keularts IM, Zivelin A, Seligsohn U, Hemker HC, Beguin S: The role of factor XI in thrombin generation induced by low concentrations of tissue factor. Thromb Haemost 2001, 85:1060-1065.
    • (2001) Thromb Haemost , vol.85 , pp. 1060-1065
    • Keularts, I.M.1    Zivelin, A.2    Seligsohn, U.3    Hemker, H.C.4    Beguin, S.5
  • 33
    • 84865172865 scopus 로고    scopus 로고
    • Thrombin generation: what have we learned?
    • Al Dieri R, de Laat B, Hemker HC: Thrombin generation: what have we learned? Blood Rev 2012, 26:197-203. 10.1016/j.blre.2012.06.001.
    • (2012) Blood Rev , vol.26 , pp. 197-203
    • Al Dieri, R.1    de Laat, B.2    Hemker, H.C.3
  • 34
    • 84870242904 scopus 로고    scopus 로고
    • Thrombin generation assay: a new tool to predict and optimize clinical outcome in cardiovascular patients?
    • Campo G, Pavasini R, Pollina A, Fileti L, Marchesini J, Tebaldi M, Ferrari R: Thrombin generation assay: a new tool to predict and optimize clinical outcome in cardiovascular patients? Blood Coagul Fibrinolysis 2012, 23:680-687. 10.1097/MBC.0b013e328355111f.
    • (2012) Blood Coagul Fibrinolysis , vol.23 , pp. 680-687
    • Campo, G.1    Pavasini, R.2    Pollina, A.3    Fileti, L.4    Marchesini, J.5    Tebaldi, M.6    Ferrari, R.7
  • 36
    • 22744445174 scopus 로고    scopus 로고
    • Thrombin generation and phenotypic correlation in haemophilia A
    • Beltran-Miranda CP, Khan A, Jaloma-Cruz AR, Laffan MA: Thrombin generation and phenotypic correlation in haemophilia A. Haemophilia 2005, 11:326-334. 10.1111/j.1365-2516.2005.01107.x.
    • (2005) Haemophilia , vol.11 , pp. 326-334
    • Beltran-Miranda, C.P.1    Khan, A.2    Jaloma-Cruz, A.R.3    Laffan, M.A.4
  • 37
    • 63049137583 scopus 로고    scopus 로고
    • Thrombin generation assay: a useful routine check-up tool in the management of patients with haemophilia?
    • Salvagno GL, Astermark J, Lippi G, Ekman M, Franchini M, Guidi GC, Berntorp E: Thrombin generation assay: a useful routine check-up tool in the management of patients with haemophilia? Haemophilia 2009, 15:290-296. 10.1111/j.1365-2516.2008.01877.x.
    • (2009) Haemophilia , vol.15 , pp. 290-296
    • Salvagno, G.L.1    Astermark, J.2    Lippi, G.3    Ekman, M.4    Franchini, M.5    Guidi, G.C.6    Berntorp, E.7
  • 38
    • 84877607719 scopus 로고    scopus 로고
    • Thrombin generation and whole blood viscoelastic assays in the management of hemophilia: current state of art and future perspectives
    • Young G, Sorensen B, Dargaud Y, Negrier C, Brummel-Ziedins K, Key NS: Thrombin generation and whole blood viscoelastic assays in the management of hemophilia: current state of art and future perspectives. Blood 2013, 121:1944-1950. 10.1182/blood-2012-08-378935.
    • (2013) Blood , vol.121 , pp. 1944-1950
    • Young, G.1    Sorensen, B.2    Dargaud, Y.3    Negrier, C.4    Brummel-Ziedins, K.5    Key, N.S.6
  • 39
    • 84879892470 scopus 로고    scopus 로고
    • Feasibility of using thrombin generation assay (TGA) for monitoring bypassing agent therapy in patients with hemophilia having inhibitors
    • Ay Y, Balkan C, Karapinar DY, Akin M, Bilenoglu B, Kavakli K: Feasibility of using thrombin generation assay (TGA) for monitoring bypassing agent therapy in patients with hemophilia having inhibitors. Clin Appl Thromb Hemost 2013, 19:389-394. 10.1177/1076029612438611.
    • (2013) Clin Appl Thromb Hemost , vol.19 , pp. 389-394
    • Ay, Y.1    Balkan, C.2    Karapinar, D.Y.3    Akin, M.4    Bilenoglu, B.5    Kavakli, K.6
  • 42
    • 84864491871 scopus 로고    scopus 로고
    • Whole-blood thrombin generation monitored with a calibrated automated thrombogram-based assay
    • Ninivaggi M, Apitz-Castro R, Dargaud Y, de Laat B, Hemker HC, Lindhout T: Whole-blood thrombin generation monitored with a calibrated automated thrombogram-based assay. Clin Chem 2012, 58:1252-1259. 10.1373/clinchem.2012.184077.
    • (2012) Clin Chem , vol.58 , pp. 1252-1259
    • Ninivaggi, M.1    Apitz-Castro, R.2    Dargaud, Y.3    de Laat, B.4    Hemker, H.C.5    Lindhout, T.6
  • 44
    • 84870255216 scopus 로고    scopus 로고
    • Evaluation of a standardized protocol for thrombin generation measurement using the calibrated automated thrombogram: an international multicentre study
    • Dargaud Y, Wolberg AS, Luddington R, Regnault V, Spronk H, Baglin T, Lecompte T, Ten Cate H, Negrier C: Evaluation of a standardized protocol for thrombin generation measurement using the calibrated automated thrombogram: an international multicentre study. Thromb Res 2012, 130:929-934. 10.1016/j.thromres.2012.07.017.
    • (2012) Thromb Res , vol.130 , pp. 929-934
    • Dargaud, Y.1    Wolberg, A.S.2    Luddington, R.3    Regnault, V.4    Spronk, H.5    Baglin, T.6    Lecompte, T.7    Ten Cate, H.8    Negrier, C.9
  • 45
    • 48949102232 scopus 로고    scopus 로고
    • Assessment of thrombin generation II: Validation of the Calibrated Automated Thrombogram in platelet-poor plasma in a clinical laboratory
    • Spronk HM, Dielis AW, De Smedt E, van Oerle R, Fens D, Prins MH, Hamulyak K, ten Cate H: Assessment of thrombin generation II: Validation of the Calibrated Automated Thrombogram in platelet-poor plasma in a clinical laboratory. Thromb Haemost 2008, 100:362-364.
    • (2008) Thromb Haemost , vol.100 , pp. 362-364
    • Spronk, H.M.1    Dielis, A.W.2    De Smedt, E.3    van Oerle, R.4    Fens, D.5    Prins, M.H.6    Hamulyak, K.7    ten Cate, H.8
  • 47
    • 84893514460 scopus 로고    scopus 로고
    • Towards standardization of clot waveform analysis and recommendations for its clinical applications
    • Shima M, Thachil J, Nair SC, Srivastava A: Towards standardization of clot waveform analysis and recommendations for its clinical applications. J Thromb Haemost 2013, 11:1417-1420. 10.1111/jth.12287.
    • (2013) J Thromb Haemost , vol.11 , pp. 1417-1420
    • Shima, M.1    Thachil, J.2    Nair, S.C.3    Srivastava, A.4
  • 48
    • 0036886325 scopus 로고    scopus 로고
    • Waveform analysis of clotting test optical profiles in the diagnosis and management of disseminated intravascular coagulation (DIC)
    • Toh CH, Giles AR: Waveform analysis of clotting test optical profiles in the diagnosis and management of disseminated intravascular coagulation (DIC). Clin Lab Haematol 2002, 24:321-327. 10.1046/j.1365-2257.2002.00457.x.
    • (2002) Clin Lab Haematol , vol.24 , pp. 321-327
    • Toh, C.H.1    Giles, A.R.2
  • 49
    • 0031949847 scopus 로고    scopus 로고
    • Early identification and prognostic implications in disseminated intravascular coagulation through transmittance waveform analysis
    • Downey C, Kazmi R, Toh CH: Early identification and prognostic implications in disseminated intravascular coagulation through transmittance waveform analysis. Thromb Haemost 1998, 80:65-69.
    • (1998) Thromb Haemost , vol.80 , pp. 65-69
    • Downey, C.1    Kazmi, R.2    Toh, C.H.3
  • 50
    • 10644283860 scopus 로고    scopus 로고
    • Prospective validation of the International Society of Thrombosis and Haemostasis scoring system for disseminated intravascular coagulation
    • Bakhtiari K, Meijers JC, de Jonge E, Levi M: Prospective validation of the International Society of Thrombosis and Haemostasis scoring system for disseminated intravascular coagulation. Crit Care Med 2004, 32:2416-2421. 10.1097/01.CCM.0000147769.07699.E3.
    • (2004) Crit Care Med , vol.32 , pp. 2416-2421
    • Bakhtiari, K.1    Meijers, J.C.2    de Jonge, E.3    Levi, M.4
  • 51
    • 61849136778 scopus 로고    scopus 로고
    • Guidelines for the diagnosis and management of disseminated intravascular coagulation: British Committee for Standards in Haematology
    • Levi M, Toh CH, Thachil J, Watson HG: Guidelines for the diagnosis and management of disseminated intravascular coagulation: British Committee for Standards in Haematology. Br J Haematol 2009, 145:24-33. 10.1111/j.1365-2141.2009.07600.x.
    • (2009) Br J Haematol , vol.145 , pp. 24-33
    • Levi, M.1    Toh, C.H.2    Thachil, J.3    Watson, H.G.4
  • 52
    • 0842342599 scopus 로고    scopus 로고
    • Understanding the hemostatic effects of recombinant factor VIIa by clot wave form analysis
    • Shima M: Understanding the hemostatic effects of recombinant factor VIIa by clot wave form analysis. Semin Hematol 2004, 41:125-131.
    • (2004) Semin Hematol , vol.41 , pp. 125-131
    • Shima, M.1
  • 54
    • 1242342711 scopus 로고    scopus 로고
    • Utility of activated partial thromboplastin time waveform analysis for identification of sepsis and overt disseminated intravascular coagulation in patients admitted to a surgical intensive care unit
    • Dempfle CE, Lorenz S, Smolinski M, Wurst M, West S, Houdijk WP, Quintel M, Borggrefe M: Utility of activated partial thromboplastin time waveform analysis for identification of sepsis and overt disseminated intravascular coagulation in patients admitted to a surgical intensive care unit. Crit Care Med 2004, 32:520-524. 10.1097/01.CCM.0000110678.52863.F3.
    • (2004) Crit Care Med , vol.32 , pp. 520-524
    • Dempfle, C.E.1    Lorenz, S.2    Smolinski, M.3    Wurst, M.4    West, S.5    Houdijk, W.P.6    Quintel, M.7    Borggrefe, M.8
  • 55
    • 33847701677 scopus 로고    scopus 로고
    • [The abnormal activated partial thromboplastin time biphasic waveform: a red flag in the sepsis? Technique and interest as marker of the sepsis]
    • Vuilliez A, Floccard B, Sobas F, Chopin N, Allaouchiche B: [The abnormal activated partial thromboplastin time biphasic waveform: a red flag in the sepsis? Technique and interest as marker of the sepsis]. Ann Fr Anesth Reanim 2007, 26:259-262. 10.1016/j.annfar.2006.11.013.
    • (2007) Ann Fr Anesth Reanim , vol.26 , pp. 259-262
    • Vuilliez, A.1    Floccard, B.2    Sobas, F.3    Chopin, N.4    Allaouchiche, B.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.