Biosynthetic versatility and coordinated action of 5′-deoxyadenosyl radicals in deazaflavin biosynthesis

Journal of the American Chemical Society

Volumn 137, Issue 16, 2015, Pages 5406-5413

  Philmus, Benjamin ^a,d   Decamps, Laure ^b,c   Berteau, Olivier ^b,c   Begley, Tadhg P ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

^b UMR1319 MICALIS   (France)

^c AGROPARISTECH   (France)

^d OREGON STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; ATOMS; BIOCHEMISTRY; ENZYMES;

ACTINOBACTERIA; CATALYTIC MOTIF; CATALYZED REACTIONS; COMPLEX ENZYMES; COORDINATED ACTIONS; DERIVED PRODUCTS; HYDROGEN ATOMS; MECHANISTIC STUDIES;

BIOSYNTHESIS;

5 DEAZAFLAVINE DERIVATIVE; CYSTEINE; DEOXYADENOSINE; DEUTERIUM; HYDROGEN; PROTEIN VARIANT; RADICAL; SYNTHETASE; TYROSINE; COENZYME F420; FREE RADICAL; RIBOFLAVIN; RIBOFLAVIN SYNTHASE;

ARTICLE; BIOSYNTHESIS; CARBOXY TERMINAL SEQUENCE; CHEMICAL REACTION; CONTROLLED STUDY; ENZYMOLOGY; HETERONUCLEAR SINGLE QUANTUM COHERENCE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; OXIDATION; PROTON NUCLEAR MAGNETIC RESONANCE; STEREOCHEMISTRY; TANDEM MASS SPECTROMETRY; ACTINOBACTERIA; ANALOGS AND DERIVATIVES; CHEMISTRY; METABOLISM;

ACTINOBACTERIA; BIOSYNTHETIC PATHWAYS; FREE RADICALS; RIBOFLAVIN; RIBOFLAVIN SYNTHASE; TYROSINE;

EID: 84928709535     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja513287k     Document Type: Article

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