메뉴 건너뛰기




Volumn 21, Issue 4, 2014, Pages 181-191

Phase II study of bevacizumab, capecitabine, and oxaliplatin followed by bevacizumab plus erlotinib as first-line therapy in metastatic colorectal cancer

Author keywords

Bevacizumab; Capecitabine; Metastatic colorectal cancer pyrighl; Oxaliplatin

Indexed keywords

BEVACIZUMAB; CAPECITABINE; ERLOTINIB; K RAS PROTEIN; OXALIPLATIN;

EID: 84928629659     PISSN: 09650407     EISSN: 15553906     Source Type: Journal    
DOI: 10.3727/096504014X13887748696743     Document Type: Article
Times cited : (9)

References (30)
  • 2
    • 1842569206 scopus 로고    scopus 로고
    • A randomized controlled trial of fluorouracil plus leucovorin, irinotecan, and oxaliplatin combinations in patients with previously untreated metastatic colorectal cancer
    • Goldberg, R. M; Sargent, D. J.; Morion, R. F.; Fuchs, C. S.; Ramanalhan, R. K.; Williamson, S. K.; Findlay, B. P.; Piloi, H. C; Alberts, S. R. A randomized controlled trial of fluorouracil plus leucovorin, irinotecan, and oxaliplatin combinations in patients with previously untreated metastatic colorectal cancer. J. Clin. Oncol. 22:23-30; 2004.
    • (2004) J. Clin. Oncol. , vol.22 , pp. 23-30
    • Goldberg, R.M.1    Sargent, D.J.2    Morion, R.F.3    Fuchs, C.S.4    Ramanalhan, R.K.5    Williamson, S.K.6    Findlay, B.P.7    Piloi, H.C.8    Alberts, S.R.9
  • 4
    • 33746805967 scopus 로고    scopus 로고
    • Randomized controlled trial of reduceddose bolus fluorouracil plus leucovorin and irinotecan or infused fluorouracil plus leucovorin and oxaliplatin in patients with previously untreated metastatic colorectal cancer: A North American Intergroup Trial
    • Goldberg, R. M.; Sargent, D. J.; Morion, R. F.; Fuchs, C. S.; Ramanalhan, R. K.; Williamson, S. K.; Findlay, B. P.; Pilot, H. C; Alberts, S. Randomized controlled trial of reduceddose bolus fluorouracil plus leucovorin and irinotecan or infused fluorouracil plus leucovorin and oxaliplatin in patients with previously untreated metastatic colorectal cancer: A North American Intergroup Trial. J. Clin. Oncol. 24:3347-3353;2006.
    • (2006) J. Clin. Oncol. , vol.24 , pp. 3347-3353
    • Goldberg, R.M.1    Sargent, D.J.2    Morion, R.F.3    Fuchs, C.S.4    Ramanalhan, R.K.5    Williamson, S.K.6    Findlay, B.P.7    Pilot, H.C.8    Alberts, S.9
  • 11
    • 36048982143 scopus 로고    scopus 로고
    • Phase II study of efficacy and safety of bevacizumab in combination with chemotherapy or erlolinib compared with chemotherapy alone for treatment of recurrent or refractory non-small cell lung cancer
    • Herbst, R. S.; O'Neill, V. J.; Fehrenbacher, L.; Belani, C. P.; Bonomi, P. D.; Hart, L.; Melnyk, O.; Ramies, D.; Lin, M.; Sandler, A. Phase II study of efficacy and safety of bevacizumab in combination with chemotherapy or erlolinib compared with chemotherapy alone for treatment of recurrent or refractory non-small cell lung cancer. J. Clin. Oncol. 25:4743-4750;2007.
    • (2007) J. Clin. Oncol. , vol.25 , pp. 4743-4750
    • Herbst, R.S.1    O'Neill, V.J.2    Fehrenbacher, L.3    Belani, C.P.4    Bonomi, P.D.5    Hart, L.6    Melnyk, O.7    Ramies, D.8    Lin, M.9    Sandler, A.10
  • 13
    • 0034594628 scopus 로고    scopus 로고
    • New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United Stales, National Cancer Institute of Canada
    • Therasse, P.; Arbuck, S. G.; Eisenhauer, E. A.; Wanders, J.; Kaplan, R. S.; Rubinstein, L.; Verweij, J.; Van Glabbeke, M.; Van Oosterom, A. T.; Christian, M. C; Gwylher, S. G. New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United Stales, National Cancer Institute of Canada. J. Natl. Cancer Inst. 92(3):205-2l6; 2000.
    • (2000) J. Natl. Cancer Inst. , vol.92 , Issue.3 , pp. 205-2l6
    • Therasse, P.1    Arbuck, S.G.2    Eisenhauer, E.A.3    Wanders, J.4    Kaplan, R.S.5    Rubinstein, L.6    Verweij, J.7    Van Glabbeke, M.8    Van Oosterom, A.T.9    Christian, M.C.10    Gwylher, S.G.11
  • 15
    • 77955164514 scopus 로고    scopus 로고
    • Phase III study of first-line XELOX plus bevacizumab (BEV) for 6 cycles followed by XELOX plus BEV or single-agent (s/a) BEV as maintenance therapy in patients (pts) wilh metastatic colorectal cancer (mCRC): The MACRO Trial (Spanish Cooperative Group for the Treatment of Digestive Tumors (TTD])
    • Tabernero, J. A. E.; Gomez, A.; Massuti, B.; Sastre, J.; Abad, A. Phase III study of first-line XELOX plus bevacizumab (BEV) for 6 cycles followed by XELOX plus BEV or single-agent (s/a) BEV as maintenance therapy in patients (pts) wilh metastatic colorectal cancer (mCRC): The MACRO Trial (Spanish Cooperative Group for the Treatment of Digestive Tumors (TTD]). J. Clin. Oncol. 28(Suppl; Abstr 3501):15s; 2010.
    • (2010) J. Clin. Oncol. , vol.28 , pp. 15s
    • Tabernero, J.A.E.1    Gomez, A.2    Massuti, B.3    Sastre, J.4    Abad, A.5
  • 17
    • 77949524888 scopus 로고    scopus 로고
    • MFOLFOX-bevacizumab or XELOX-bevacizumab then bevacizumab (B) alone or with erlolinib (E) in first-line treatment of patients with metastatic colorectal cancer (mCRC): Interim safely analysis of DREAM study
    • Tournigand. C. S. B.; Scheithauer, W.; Louvet, C; Andre, T; Lledo G.; et al. mFOLFOX-bevacizumab or XELOX-bevacizumab then bevacizumab (B) alone or with erlolinib (E) in first-line treatment of patients with metastatic colorectal cancer (mCRC): Interim safely analysis of DREAM study. J. Clin. Oncol. 27(Suppl; Abstr 4077):15s; 2009.
    • (2009) J. Clin. Oncol. , vol.27 , pp. 15s
    • Tournigand, C.S.B.1    Scheithauer, W.2    Louvet, C.3    Andre, T.4    Lledo, G.5
  • 22
    • 84862987061 scopus 로고    scopus 로고
    • Dual targeting of the epidermal growth factor receptor using the combination of celuximab and erlotinib: Preclinical evaluation and results of the phase II DUX study in chemotherapy-refractory, advanced colorectal cancer
    • Weickhardt, A. J.; Price, T. J.; Chong, G.; Gebski, V; Pavlakis, N.; Johns, T. G.; Azad, A.; Skrinos, E.; Fluck, K.; Dobrovic, A.; Salemi, R.; Scott, A. M.; Mariadason, J. M.; Tebbutt, N. C. Dual targeting of the epidermal growth factor receptor using the combination of celuximab and erlotinib: Preclinical evaluation and results of the phase II DUX study in chemotherapy-refractory, advanced colorectal cancer. J. Clin. Oncol. 30(13):1505-12; 2012.
    • (2012) J. Clin. Oncol. , vol.30 , Issue.13 , pp. 1505-1512
    • Weickhardt, A.J.1    Price, T.J.2    Chong, G.3    Gebski, V.4    Pavlakis, N.5    Johns, T.G.6    Azad, A.7    Skrinos, E.8    Fluck, K.9    Dobrovic, A.10    Salemi, R.11    Scott, A.M.12    Mariadason, J.M.13    Tebbutt, N.C.14
  • 24
    • 84856271990 scopus 로고    scopus 로고
    • Are KRAS/BRAF mutations potent prognostic and/or predictive biomarkers in colorectal cancers?
    • Yokola, T. Are KRAS/BRAF mutations potent prognostic and/or predictive biomarkers in colorectal cancers? Anticancer Agents Med. Chem. 12:163-71; 2012.
    • (2012) Anticancer Agents Med. Chem. , vol.12 , pp. 163-171
    • Yokola, T.1
  • 26
    • 34249810645 scopus 로고    scopus 로고
    • KRAS mutation is an important predictor of resistance to therapy with epidermal growth factor receptor tyrosine kinase inhibitors in non-small-cell lung cancer
    • Massarelll, E.; Varella-Garcia, M.; Tang, X.; Xavier, A. C; Ozburn, N. C; Liu, D. D.; Bekele, B. N.; Herbst, R. S.; Wistuha, I. I. KRAS mutation is an important predictor of resistance to therapy with epidermal growth factor receptor tyrosine kinase inhibitors in non-small-cell lung cancer. Clin. Cancer Res 13:2890-2896;2007.
    • (2007) Clin. Cancer Res , vol.13 , pp. 2890-2896
    • Massarelll, E.1    Varella-Garcia, M.2    Tang, X.3    Xavier, A.C.4    Ozburn, N.C.5    Liu, D.D.6    Bekele, B.N.7    Herbst, R.S.8    Wistuha, I.I.9
  • 28
    • 77649114574 scopus 로고    scopus 로고
    • Genetic and proteomic features associated with survival after treatment with erlotinib in first-line therapy of non-small cell lung cancer in Eastern Cooperative Oncology Group 3503
    • Ainann, J. M.; Lee, J. W.; Roder, H.; Brahmcr, J.; Gonzalez, A.; Schiller, J. H.; Carbonc, D. P. Genetic and proteomic features associated with survival after treatment with erlotinib in first-line therapy of non-small cell lung cancer in Eastern Cooperative Oncology Group 3503. J. Thoraic Oncol. 5:169-178; 2010.
    • (2010) J. Thoraic Oncol. , vol.5 , pp. 169-178
    • Ainann, J.M.1    Lee, J.W.2    Roder, H.3    Brahmcr, J.4    Gonzalez, A.5    Schiller, J.H.6    Carbonc, D.P.7
  • 29
    • 56849092722 scopus 로고    scopus 로고
    • Activity of the combination of bevaeizumab (Bev) with capecitahine/irhiolecan (Caplri/Bev) or capecitabine/oxaliplalin (CapOx/Bev) in advanced colorectal cancer (ACRC): A randomized phase II study of the AIO Colorectal Study Group (AIO trial 0604)
    • Reinacher-Schick, A. K. S.; Freier, W; Arnold, D; Dietrich, G; Geisslcr, M; et al. Activity of the combination of bevaeizumab (Bev) with capecitahine/irhiolecan (Caplri/Bev) or capecitabine/oxaliplalin (CapOx/Bev) in advanced colorectal cancer (ACRC): A randomized phase II study of the AIO Colorectal Study Group (AIO trial 0604). J. Clin. Oncol 26(Suppl; Abslr 4030); 2008.
    • (2008) J. Clin. Oncol , vol.26
    • Reinacher-Schick, A.K.S.1    Freier, W.2    Arnold, D.3    Dietrich, G.4    Geisslcr, M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.