Design and performance evaluation of a linear ion trap mass analyzer featuring half round rod electrodes

Journal of the American Society for Mass Spectrometry

Volumn 26, Issue 5, 2015, Pages 734-740

  Li, Xiaoxu ^a   Zhang, Xiaohua ^b   Yao, Rujiao ^a   He, Yang ^a   Zhu, Yongyong ^a   Qian, Jie ^a  

^a SOOCHOW UNIVERSITY   (China)

^b FUDAN UNIVERSITY   (China)

Author keywords

Linear ion trap; Mass analyzer; Mass resolution; Radial ejection; Round rod electrode

Indexed keywords

ELECTRODES; MASS SPECTROMETRY; STAINLESS STEEL;

LINEAR ION TRAP; MASS ANALYZERS; MASS RESOLUTION; RADIAL EJECTION; ROUND ROD;

IONS;

RESERPINE; STAINLESS STEEL;

ANALYTICAL EQUIPMENT; ARTICLE; COLLISIONALLY ACTIVATED DISSOCIATION; ELECTRIC FIELD; ELECTRODE; HALF ROUND ROD ELECTRODE; ION TRAP MASS SPECTROMETRY; MASS SPECTROMETER; MEASUREMENT ACCURACY; POWER SUPPLY; PUMP; TANDEM MASS SPECTROMETRY;

EID: 84928578907     PISSN: 10440305     EISSN: 18791123     Source Type: Journal    
DOI: 10.1007/s13361-015-1085-2     Document Type: Article

References (34)

1. March, R.E.: An introduction to quadrupole ion trap mass spectrometry. J. Mass Spectrom. 32, 351-369 (1997)
2. March, R.E.: Quadrupole ion trap mass spectrometry: theory, simulation, recent developments, and applications. Rapid Commun. Mass Spectrom. 12, 1543-1554 (1998)
3. March, R.E.: Quadrupole ion traps. Mass Spectrom. Rev. 28, 961-989 (2009)
4. Harbourt, D.E., Fallon, J.K., Ito, S., Baba, T., Ritter, J.K., Glish, G.L., Smith, P.C.: Quantification of human uridine-diphosphate glucuronosyl transferase 1A isoforms in liver, intestine, and kidney using nanobore liquid chromatography-tandem mass spectrometry. Anal. Chem. 84, 98-105 (2012)
5. Harrison, S., Xue, H., Lane, G., Villas-Boas, S., Rasmussen, S.: Linear ion trap msn of enzymatically synthesized 13C-labeled fructans revealing differentiating fragmentation patterns of beta (1-2) and beta (1-6) fructans and providing a tool for oligosaccharide identification in complex mixtures. Anal. Chem. 84, 1540-1548 (2012)
6. Wang, D., Hincapie, M., Rejtar, T., Karger, B.L.: Ultrasensitive characterization of site-specific glycosylation of affinity-purified haptoglobin from lung cancer patient plasma using 10 mu m i.d. porous layer open tubular liquid chromatography-linear ion trap collision-induced dissociation/electron transfer dissociation mass spectrometry. Anal. Chem. 83, 2029-2037 (2011)
7. Bereman, M.S., Canterbury, J.D., Egertson, J.D., Horner, J., Remes, P.M., Schwartz, J., Zabrouskoy, V., MacCoss, M.J.: Evaluation of front-end higher energy collision-induced dissociation on a benchtop dual-pressure linear ion trap mass spectrometer for shotgun proteomics. Anal. Chem. 84, 1533-1539 (2012)
8. Schwartz, J.C., Senko, M.W., Syka, J.E.P.: A two-dimensional quadrupole ion trap mass spectrometer. J. Am. Soc. Mass Spectrom. 13, 659-669 (2002)
9. Hager, J.W.: A new linear ion trap mass spectrometer. Rapid Commun. Mass Spectrom. 16, 512-526 (2002)
10. Londry, F.A., Hager, J.W.: Mass selective axial ion ejection from a linear quadrupole ion trap. J. Am. Soc. Mass Spectrom. 14, 1130-1147 (2003)
11. Song, Q.Y., Kothari, S., Senko, M.A., Schwartz, J.C., Amy, J.W., Stafford, G.C., Cooks, R.G., Ouyang, Z.: Rectilinear ion trap mass spectrometer with atmospheric pressure interface and electrospray ionization source. Anal. Chem. 78, 718-725 (2006)
12. Ouyang, Z., Wu, G.X., Song, Y.S., Li, H.Y., Plass, W.R., Cooks, R.G.: Rectilinear ion trap: concepts, calculations, and analytical performance of a new mass analyzer. Anal. Chem. 76, 4595-4605 (2004)
13. Gao, L., Song, Q., Patterson, G.E., Cooks, R.G., Ouyang, Z.: Handheld rectilinear ion trap mass spectrometer. Anal. Chem. 78, 5994-6002 (2006)
14. Jiang, J., Fei, Q., Jin, W., Li, M., Pang, X.-D., Li, B., Fan, Z.-Y., Xu, X.-Y., Zhou, J.-G., Jin, Q.-H.: Miniature rectilinear ion trap mass spectrometry. Chin. J. Anal. Chem. 35, 1387-1390 (2007)
15. Fico, M., Yu, M., Ouyang, Z., Cooks, R.G., Chappell, W.J.: Miniaturization and geometry optimization of a polymer-based rectilinear ion trap. Anal. Chem. 79, 8076-8082 (2007)
16. Erickson, B.E.: Miniaturized rectilinear ion trap. Anal. Chem. 76, 305A (2004)
17. Graichen, A.M., Vachet, R.W.: Multiplexed MS/MS in a miniature rectilinear ion trap. J. Am. Soc. Mass Spectrom. 22, 683-688 (2011)
18. Chen, T.-C., Xu, W., Ouyang, Z.: Dual buffer gases for ion manipulation in a miniature ion trap mass spectrometer with a discontinuous atmospheric pressure interface. Rapid Commun. Mass Spectrom. 25, 3274-3280 (2011)
19. Ouyang, Z., Noll, R.J., Cooks, R.G.: Handheld miniature ion trap mass spectrometers. Anal. Chem. 81, 2421-2425 (2009)
20. Li, X., Jiang, G., Luo, C., Xu, F., Wang, Y., Ding, L., Ding, C.-F.: Ion trap array mass analyzer: structure and performance. Anal. Chem. 81, 4840-4846 (2009)
21. Chu, Y.-Q., Xiao, Y., Ling, X., Ding, C.-F.: Analytical performance of printed circuit board ion trap array mass analyzer with electrospray ionization. Chin. J. Anal. Chem. 41, 152-158 (2013)
22. Xiao, Y., Chu, Y., Ling, X., Ding, Z., Xu, C., Ding, L., Ding, C.-F.: Multiple mass analysis using an ion trap array (ITA) mass analyzer. J. Am. Soc. Mass Spectrom. 24, 1420-1427 (2013)
23. Luo, C., Ding, C.-F.: Optimization of ion trap array mass analyzer by computer simulation. Chin. J. Anal. Chem. 40, 989-995 (2012)
24. Xiao, Y., Ding, Z., Xu, C., Dai, X., Fang, X., Ding, C.-F.: Novel linear ion trap mass analyzer built with triangular electrodes. Anal. Chem. 86, 5733-5739 (2014)
25. Keil, A., Hernandez-Soto, H., Noll, R.J., Fico, M., Gao, L., Ouyang, Z., Cooks, R.G.: Monitoring of toxic compounds in air using a handheld rectilinear ion trap mass spectrometer. Anal. Chem. 80, 734-741 (2008)
26. Chen, T.-C., Ouyang, Z.: Synchronized discharge ionization for analysis of volatile organic compounds using a hand-held ion trap mass spectrometer. Anal. Chem. 85, 1767-1772 (2013)
27. Douglas, D.J., Konenkov, N.V.: Influence of the 6th and 10th spatial harmonics on the peak shape of a quadrupole mass filter with round rods. Rapid Commun. Mass Spectrom. 16, 1425-1431 (2002)
28. Schulte, J., Shevchenko, P.V., Radchik, A.V.: Nonlinear field effects in quadrupole mass filters. Rev. Sci. Instrum. 70, 3566-3571 (1999)
29. Gibson, J.R., Taylor, S.: Numerical investigation of the effect of electrode size on the behaviour of quadrupole mass filters. Rapid Commun. Mass Spectrom. 15, 1960-1964 (2001)
30. Xiao, Z., Zhao, X., Douglas, D.J.: Quadrupole mass filters with added hexapole fields. Rapid Commun. Mass Spectrom. 24, 1985-1992 (2010)
31. Ding, C.F., Konenkov, N.V., Douglas, D.J.: Quadrupole mass filters with octopole fields. Rapid Commun. Mass Spectrom. 17, 2495-2502 (2003)
32. Douglas, D.J., Konenkov, N.V.: Mass resolution of linear quadrupole ion traps with round rods. Rapid Commun. Mass Spectrom. 28, 2252-2258 (2014)
33. Schwartz, J.C., Syka, J.E.P., Jardine, I.: High-resolution on a quadrupole ion trap mass-spectrometer. J. Am. Soc. Mass Spectrom. 2, 198-204 (1991)
34. Williams, J.D., Cox, K.A., Cooks, R.G., Kaiser, R.E., Schwartz, J.C.: High mass-resolution using a quadrupole ion-trap mass-spectrometer. Rapid Commun. Mass Spectrom. 5, 327-329 (1991)