Concise review: Are stimulated somatic cells truly reprogrammed into an ES/iPS-like pluripotent state? better understanding by ischemia-induced multipotent stem cells in a mouse model of cerebral infarction

Stem Cells International

Volumn 2015, Issue , 2015, Pages

  Nakagomi, Takayuki ^a   Nakano Doi, Akiko ^a   Narita, Aya ^a   Matsuyama, Tomohiro ^a  

^a HYOGO COLLEGE OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; FIBROBLAST GROWTH FACTOR 2; KRUPPEL LIKE FACTOR 4; LEUKEMIA INHIBITORY FACTOR; MEMBRANE PROTEIN; MYC PROTEIN; OCTAMER TRANSCRIPTION FACTOR 4; OCTAMER TRANSCRIPTION FACTOR 4A; OCTAMER TRANSCRIPTION FACTOR 4B; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; PROTEIN NG2; STAGE SPECIFIC EMBRYO ANTIGEN 1; STAGE SPECIFIC EMBRYO ANTIGEN 4; TRANSCRIPTION FACTOR NANOG; UNCLASSIFIED DRUG;

BRAIN INFARCTION; BRAIN ISCHEMIA; CELL LINEAGE; CELL RENEWAL; DENTATE GYRUS; EMBRYONIC STEM CELL; ENVIRONMENTAL FACTOR; HIPPOCAMPUS; HUMAN; IN VIVO STUDY; ISCHEMIA; NEURAL STEM CELL; NONHUMAN; NUCLEAR REPROGRAMMING; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVIEW; SOMATIC CELL THERAPY; VERY SMALL EMBRYONIC LIKE STEM CELL;

IPS;

EID: 84928554168     PISSN: None     EISSN: 16879678     Source Type: Journal    
DOI: 10.1155/2015/630693     Document Type: Review

References (58)

1. K. Takahashi and S. Yamanaka, "Induction of of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors, " Cell, vol. 126, no. 4, pp. 663-676, 2006.
2. K. Takahashi, K. Tanabe, M. Ohnuki et al., "Induction of pluripotent stem cells from adult human fibroblasts by defined factors, " Cell, vol. 131, no. 5, pp. 861-872, 2007.
3. M. Thier, P. Wörsdörfer, Y. B. Lakes et al., "Direct conversion of fibroblasts into stably expandable neural stem cells, " Cell Stem Cell, vol. 10, no. 4, pp. 473-479, 2012.
4. K. Yanger, Y. Zong, L. R. Maggs et al., "Robust cellular reprogramming occurs spontaneously during liver regeneration, " Genes and Development, vol. 27, no. 7, pp. 719-724, 2013.
5. A. Luz-Madrigal, E. Grajales-Esquivel, A. McCorkle et al., "Reprogramming of the chick retinal pigmented epithelium after retinal injury, " BMC Biology, vol. 12, article 28, 2014.
6. I. S. Shimada, B. M. Peterson, and J. L. Spees, "Isolationof locally derived stem/progenitor cells from the peri-infarct area that do not migrate from the lateral ventricle after cortical stroke, " Stroke, vol. 41, no. 9, pp. e552-e560, 2010.
7. A. Mohyeldin, T. Garzón-Muvdi, and A. Quiñones-Hinojosa, "Oxygen in stem cell biology: a critical component of the stem cell niche, " Cell Stem Cell, vol. 7, no. 2, pp. 150-161, 2010.
8. Y. Yoshida, K. Takahashi, K. Okita, T. Ichisaka, and S. Yamanaka, "Hypoxia enhances the generation of induced pluripotent stem cells, " Cell Stem Cell, vol. 5, no. 3, pp. 237-241, 2009.
9. T. Nakagomi, Z. Molnár, A. Nakano-Doi et al., "Ischemiainduced neural stem/progenitor cells in the piamater following cortical infarction, " Stem Cells and Development, vol. 20, no. 12, pp. 2037-2051, 2011.
10. T. Nakagomi, Z. Molnár, A. Taguchi et al., "Leptomeningealderived doublecortin-expressing cells in poststroke brain, " Stem Cells and Development, vol. 21, no. 13, pp. 2350-2354, 2012.
11. T. Nakagomi, A. Nakano-Doi, and T. Matsuyama, "Leptomeninges: a novel stem cell niche harboring ischemia-induced neural progenitors, " Histology and Histopathology, vol. 30, pp. 391-399, 2015.
12. T. Nakagomi, S. Kubo, A. Nakano-Doi et al., "Brain vascular pericytes following ischemia have multipotential stem cell activity to differntiate into neural and vascular lineage cells, " Stem Cells, 2015.
13. A. Alvarez-Buylla and J. M. García-Verdugo, "Neurogenesis in adult subventricular zone, " The Journal of Neuroscience, vol. 22, no. 3, pp. 629-634, 2002.
14. H. G. Kuhn, H. Dickinson-Anson, and F. H. Gage, "Neurogenesis in the dentate gyrus of the adult rat: age-related decrease of neuronal progenitor proliferation, " Journal of Neuroscience, vol. 16, no. 6, pp. 2027-2033, 1996.
15. A. Kriegstein and A. Alvarez-Buylla, "The glial nature of embryonic and adult neural stem cells, " Annual Review of Neuroscience, vol. 32, pp. 149-184, 2009.
16. F. Doetsch, J. M. García-Verdugo, and A. Alvarez-Buylla, "Regeneration of a germinal layer in the adult mammalian brain, " Proceedings of the National Academy of Sciences of the United States of America, vol. 96, no. 20, pp. 11619-11624, 1999.
17. S. Belachew, R. Chittajallu, A. A. Aguirre et al., "PostnatalNG2 proteoglycan-expressing progenitor cells are intrinsicallymultipotent and generate functional neurons, " Journal of Cell Biology, vol. 161, no. 1, pp. 169-186, 2003.
18. W. D. Richardson, K. M. Young, R. B. Tripathi, and I. McKenzie, "NG2-glia as multipotent neural stem cells: fact or fantasy?" Neuron, vol. 70, no. 4, pp. 661-673, 2011.
19. T. Kondo and M. Raff, "Oligodendrocyte precursor cells reprogrammed to become multipotential CNS stem cells, " Science, vol. 289, no. 5485, pp. 1754-1757, 2000.
20. M. Ii, H. Nishimura, H. Sekiguchi et al., "Concurrent vasculogenesis and neurogenesis fromadult neural stemcells, " Circulation Research, vol. 105, no. 9, pp. 860-868, 2009.
21. K. Oishi and Y. Ito-Dufros, "Angiogenic potential of CD44+ CD90+ multipotent CNS stem cells in vitro, " Biochemical and Biophysical Research Communications, vol. 349, no. 3, pp. 1065-1072, 2006.
22. A. E. Wurmser, K. Nakashima, R. G. Summers et al., "Cell fusion-independent differentiation of neural stem cells to the endothelial lineage, " Nature, vol. 430, no. 6997, pp. 350-356, 2004.
23. T. Nakagomi, A. Taguchi, Y. Fujimori et al., "Isolation and characterization of neural stem/progenitor cells from post-stroke cerebral cortex in mice, " European Journal of Neuroscience, vol. 29, no. 9, pp. 1842-1852, 2009.
24. P. Dore-Duffy, A. Katychev, X. Wang, and E. van Buren, "CNS microvascular pericytes exhibit multipotential stem cell activity, " Journal of Cerebral Blood Flow and Metabolism, vol. 26, no. 5, pp. 613-624, 2006.
25. A. Birbrair, T. Zhang, Z.-M. Wang et al., "Skeletal muscle pericyte subtypes differ in their differentiation potential, " Stem Cell Research, vol. 10, no. 1, pp. 67-84, 2013.
26. A. Birbrair, T. Zhang, Z. M. Wang, M. L. Messi, A. Mintz, and O. Delbono, "Pericytes:multitasking cells in the regeneration of injured, diseased, and aged skeletal muscle, " Frontiers in Aging Neuroscience, vol. 6, article 245, 2014.
27. A. Birbrair, T. Zhang, Z. M. Wang et al., "Type-2 pericytes participate in normal and tumoral angiogenesis, " The American Journal of Physiology-Cell Physiology, vol. 307, pp. C25-C38, 2014.
28. M. Karow, R. Sánchez, C. Schichor et al., "Reprogramming of pericyte-derived cells of the adult human brain into induced neuronal cells, " Cell Stem Cell, vol. 11, no. 4, pp. 471-476, 2012.
29. M. J. Doherty, B. A. Ashton, S. Walsh, J. N. Beresford, M. E. Grant, and A. E. Canfield, "Vascular pericytes express osteogenic potential in vitro and in vivo, " Journal of Bone andMineral Research, vol. 13, no. 5, pp. 828-838, 1998.
30. A. Dar, H. Domev, O. Ben-Yosef et al., "Multipotent vasculogenic pericytes from human pluripotent stem cells promote recovery of murine ischemic limb, " Circulation, vol. 125, no. 1, pp. 87-99, 2012.
31. C. Farrington-Rock, N. J. Crofts, M. J. Doherty, B. A. Ashton, C. Griffin-Jones, and A. E. Canfield, "Chondrogenic and adipogenic potential of microvascular pericytes, " Circulation, vol. 110, no. 15, pp. 2226-2232, 2004.
32. J. B. Kim, H. Zaehres, G. Wu et al., "Pluripotent stem cells induced from adult neural stem cells by reprogramming with two factors, " Nature, vol. 454, no. 7204, pp. 646-650, 2008.
33. D. Bhartiya, "Are mesenchymal cells indeed pluripotent stem cells or just stromal cells? OCT-4 and VSELs biology has led to better understanding, " Stem Cells International, vol. 2013, Article ID 547501, 6 pages, 2013.
34. N. Nakagomi, T. Nakagomi, S. Kubo et al., "Endothelial cells support survival, proliferation, and neuronal differentiation of transplanted adult ischemia-induced neural stem/progenitor cells after cerebral infarction, " StemCells, vol. 27, no. 9, pp. 2185-2195, 2009.
35. A. Nakano-Doi, T. Nakagomi, M. Fujikawa et al., "Bonemarrow mononuclear cells promote proliferation of endogenous neural stem cells through vascular niches after cerebral infarction, " Stem Cells, vol. 28, no. 7, pp. 1292-1302, 2010.
36. T. Nakagomi, A. Asai, H. Kanemitsu et al., "Up-regulation of cmyc gene expression following focal ischemia in the rat brain, " Neurological Research, vol. 18, no. 6, pp. 559-563, 1996.
37. O. Hurtado, M. A. Moro, A. Cárdenas et al., "Neuroprotection afforded by prior citicoline administration in experimental brain ischemia: effects on glutamate transport, " Neurobiology of Disease, vol. 18, no. 2, pp. 336-345, 2005.
38. Y. Kubota, M. Hirashima, K. Kishi, C. L. Stewart, and T. Suda, "Leukemia inhibitory factor regulates microvessel density by modulating oxygen-dependent VEGF expression in mice, " The Journal of Clinical Investigation, vol. 118, no. 7, pp. 2393-2403, 2008.
39. J. Luo, F. Qiao, and X. Yin, "Hypoxia induces FGF2 production by vascular endothelial cells and alters MMP9 and TIMP1 expression in extravillous trophoblasts and their invasiveness in a cocultured model, " Journal of Reproduction and Development, vol. 57, no. 1, pp. 84-91, 2011.
40. M. Z. Ratajczak, D.-M. Shin, R. Liu et al., "Very Small Embryonic/Epiblast-Like stem cells (VSELs) and their potential role in aging and organ rejuvenation-an update and comparison to other primitive small stem cells isolated from adult tissues, " Aging, vol. 4, no. 4, pp. 235-246, 2012.
41. S. Parte, D. Bhartiya, J. Telang et al., "Detection, characterization, and spontaneous differentiation in vitro of very small embryonic-like putative stem cells in adult mammalian ovary, " Stem Cells and Development, vol. 20, no. 8, pp. 1451-1464, 2011.
42. M. Kucia, R. Reca, F. R. Campbell et al., "A population of very small embryonic-like (VSEL) CXCR4+SSEA-1+Oct-4+ stem cells identified in adult bone marrow, " Leukemia, vol. 20, pp. 857-869, 2006.
43. K. Grymula, M. Tarnowski, K. Piotrowska et al., "Evidence that the population of quiescent bone marrow-residing very small embryonic/epiblast-like stem cells (VSELs) expands in response to neurotoxic treatment, " Journal of Cellular and Molecular Medicine, vol. 18, no. 9, pp. 1797-1806, 2014.
44. Y. Kuroda, S. Wakao, M. Kitada, T. Murakami, M. Nojima, and M. Dezawa, "Isolation, culture and evaluation of multilineagedifferentiating stress-enduring (Muse) cells, " Nature Protocols, vol. 8, no. 7, pp. 1391-1415, 2013.
45. Y. Kuroda, M. Kitada, S. Wakao et al., "Uniquemultipotent cells in adult human mesenchymal cell populations, " Proceedings of the National Academy of Sciences of the United States of America, vol. 107, no. 19, pp. 8639-8643, 2010.
46. M. Kucia, M. Halasa, M. Wysoczynski et al., "Morphological andmolecular characterization of novel population of CXCR4+ SSEA-4+ Oct-4+ very small embryonic-like cells purified from human cord blood-Preliminary report, " Leukemia, vol. 21, no. 2, pp. 297-303, 2007.
47. K. Szade, K. Bukowska-Strakova, W. N. Nowak, A. Jozkowicz, and J. Dulak, "Comment on: the proper criteria for identification and sorting of very small embryonic-like stem cells, and some nomenclature issues, " Stem Cells andDevelopment, vol. 23, no. 7, pp. 714-716, 2014.
48. K. Szade, K. Bukowska-Strakova, W. N. Nowak et al., "Murine bone marrow Lin-Sca-1+CD45-very small embryonic-like (VSEL) cells are heterogeneous population lacking Oct-4A expression, " PLoS ONE, vol. 8, no. 5, Article ID e63329, 2013.
49. M. Miyanishi, Y. Mori, J. Seita et al., "Do pluripotent stem cells exist in adult mice as very small embryonic stem cells?" Stem Cell Reports, vol. 1, no. 2, pp. 198-208, 2013.
50. A. Poloni, G. Maurizi, P. Leoni et al., "Human dedifferentiated adipocytes show similar properties to bone marrow-derived mesenchymal stem cells, " Stem Cells, vol. 30, no. 5, pp. 965-974, 2012.
51. S. Roche, M.-J. Richard, and M.-C. Favrot, "Oct-4, Rex-1, and Gata-4 expression in human MSC increase the differentiation efficiency but not hTERT expression, " Journal of Cellular Biochemistry, vol. 101, no. 2, pp. 271-280, 2007.
52. Q. Gao, L. Zhao, Z. Song, and G. Yang, "Expression pattern of embryonic stem cell markers inDFAT cells and ADSCs, " Molecular Biology Reports, vol. 39, no. 5, pp. 5791-5804, 2012.
53. S. Hauser, D. Widera, F. Qunneis et al., "Isolation of novel multipotent neural crest-derived stem cells from adult human inferior turbinate, " Stem Cells andDevelopment, vol. 21, no. 5, pp. 742-756, 2012.
54. D. Pelaez, C.-Y. C. Huang, and H. S. Cheung, "Isolation of pluripotent neural crest-derived stem cells from adult human tissues by connexin-43 enrichment, " Stem Cells and Development, vol. 22, no. 21, pp. 2906-2914, 2013.
55. D. Widera, C. Zander, M. Heidbreder et al., "Adult palatum as a novel source of neural crest-related stem cells, " Stem Cells, vol. 27, no. 8, pp. 1899-1910, 2009.
56. J. Takeda, S. Seino, and G. I. Bell, "Human Oct3 gene family: cDNA sequences, alternative splicing, gene organization, chromosomal location, and expression at low levels in adult tissues, " Nucleic Acids Research, vol. 20, no. 17, pp. 4613-4620, 1992.
57. R. Warthemann, K. Eildermann, K. Debowski, and R. Behr, "False-positive antibody signals for the pluripotency factor OCT4A (POU5F1) in testis-derived cellsmay lead to erroneous data and misinterpretations, " Molecular Human Reproduction, vol. 18, no. 12, pp. 605-612, 2012.
58. D. C. Hay, L. Sutherland, J. Clark, and T. Burdon, "Oct-4 knockdown induces similar patterns of endoderm and trophoblast differentiation markers in human and mouse embryonic stem cells, " Stem Cells, vol. 22, no. 2, pp. 225-235, 2004.