Brazilin isolated from caesalpinia sappan L. inhibits rheumatoid arthritis activity in a type-II collagen induced arthritis mouse model

BMC Complementary and Alternative Medicine

Volumn 15, Issue 1, 2015, Pages

  Jung, Eui Gil ^a   Han, Kook Il ^a   Hwang, Seon Gu ^a   Kwon, Hyun Jung ^b   Patnaik, Bharat Bhusan ^c,d   Kim, Yong Hyun ^a   Han, Man Deuk ^a  

^a Soonchunhyang University   (South Korea)

^b Gimcheon University   (South Korea)

^c Chonnam National University   (South Korea)

^d Trident School of Biotech Sciences   (India)

Author keywords

Brazilin; Caesalpinia sappan; Collagen induced arthritis; Pro inflammatory cytokine; Rheumatoid arthritis

Indexed keywords

ANTIRHEUMATIC AGENT; BRAZILIN; CAESALPINIA SAPPAN EXTRACT; INTERLEUKIN 1BETA; INTERLEUKIN 6; METHOTREXATE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ANTIINFLAMMATORY AGENT; BENZOPYRAN DERIVATIVE; COLLAGEN TYPE 2; CYTOKINE; FREUND ADJUVANT; INCOMPLETE FREUND'S ADJUVANT; LIPID; PLANT EXTRACT; TNF PROTEIN, HUMAN; TUMOR NECROSIS FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BODY WEIGHT; BONE DENSITY; BONE MASS; CAESALPINIA; CAESALPINIA SAPPAN; CARBON NUCLEAR MAGNETIC RESONANCE; COLUMN CHROMATOGRAPHY; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG PURIFICATION; DRUG STRUCTURE; EROSION; FEMUR METAPHYSIS; GEL CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMMUNOASSAY; JOINT DESTRUCTION; MALE; MASS SPECTROMETRY; METAPHYSIS; MICRO-COMPUTED TOMOGRAPHY; MORPHOMETRICS; MOUSE; NONHUMAN; ORGAN WEIGHT; OSSIFICATION; PAW EDEMA; PROTEIN BLOOD LEVEL; PROTON NUCLEAR MAGNETIC RESONANCE; PURIFICATION; RHEUMATOID ARTHRITIS; WEIGHT REDUCTION; ANIMAL; ARTHRITIS, EXPERIMENTAL; ARTHRITIS, RHEUMATOID; BLOOD; BONE; BOVINE; CHEMISTRY; DBA MOUSE; DISEASE MODEL; DRUG EFFECTS; PHYTOTHERAPY;

ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTIRHEUMATIC AGENTS; ARTHRITIS, EXPERIMENTAL; ARTHRITIS, RHEUMATOID; BENZOPYRANS; BONE AND BONES; CAESALPINIA; CATTLE; COLLAGEN TYPE II; CYTOKINES; DISEASE MODELS, ANIMAL; FREUND'S ADJUVANT; INTERLEUKIN-1BETA; INTERLEUKIN-6; LIPIDS; MICE; MICE, INBRED DBA; PHYTOTHERAPY; PLANT EXTRACTS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84928523413     PISSN: None     EISSN: 14726882     Source Type: Journal    
DOI: 10.1186/s12906-015-0648-x     Document Type: Article

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