Prostacyclin decreases splanchnic vascular contractility in cirrhotic rats

Hepatobiliary and Pancreatic Diseases International

Volumn 13, Issue 4, 2014, Pages 416-422

  Liu, De Jun ^a   Chen, Wei ^a   Huo, Yan Miao ^a   Liu, Wei ^a   Zhang, Jun Feng ^a   Hua, Rong ^a   Sun, Yong Wei ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

indomethacin; portal hypertension; prostacyclin; protein kinase A; vascular hyporesponsiveness

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; KETONE; NORADRENALIN; PROSTACYCLIN; 6 OXOPROSTAGLANDIN F1 ALPHA; ALCOHOL; CARBON TETRACHLORIDE; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; MEMBRANE PROTEIN; PROSTAGLANDIN SYNTHASE INHIBITOR; PROTEIN KINASE INHIBITOR; PTGS1 PROTEIN, RAT; PTGS2 PROTEIN, RAT; VASOCONSTRICTOR AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERIOLE; ARTICLE; BLOOD PRESSURE; BLOOD VESSEL DIAMETER; BLOOD VESSEL REACTIVITY; CONCENTRATION RESPONSE; EC50; LIVER CIRRHOSIS; MALE; MESENTERIC ARTERY; NONHUMAN; PKA; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; SPLANCHNIC BLOOD FLOW; ANIMAL; ANTAGONISTS AND INHIBITORS; BLOOD; CHEMICALLY INDUCED; DOSE RESPONSE; DRUG EFFECTS; EXPERIMENTAL LIVER CIRRHOSIS; LIVER CIRRHOSIS, ALCOHOLIC; METABOLISM; PATHOPHYSIOLOGY; SPRAGUE DAWLEY RAT; UPREGULATION; VASOCONSTRICTION;

6-KETOPROSTAGLANDIN F1 ALPHA; ANIMALS; ARTERIOLES; CARBON TETRACHLORIDE; CYCLIC AMP-DEPENDENT PROTEIN KINASES; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; EPOPROSTENOL; ETHANOL; LIVER CIRRHOSIS, ALCOHOLIC; LIVER CIRRHOSIS, EXPERIMENTAL; MALE; MEMBRANE PROTEINS; PROTEIN KINASE INHIBITORS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; SPLANCHNIC CIRCULATION; UP-REGULATION; VASOCONSTRICTION; VASOCONSTRICTOR AGENTS;

EID: 84928392019     PISSN: 14993872     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1499-3872(14)60270-8     Document Type: Article

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