메뉴 건너뛰기




Volumn 6, Issue 10, 2015, Pages 7408-7423

Deciphering the cellular source of tumor relapse identifies CD44 as a major therapeutic target in pancreatic adenocarcinoma

Author keywords

CD44; Pancreas cancer; Recurrence; Xenograft

Indexed keywords

DOCETAXEL; FIRTECAN; FLUOROURACIL; GEMCITABINE; HERMES ANTIGEN; MUCIN 1; OXALIPLATIN; TRANSCRIPTION FACTOR ZEB1; CD44 PROTEIN, HUMAN; DEOXYCYTIDINE;

EID: 84928383798     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.3510     Document Type: Article
Times cited : (26)

References (43)
  • 4
    • 84859580551 scopus 로고    scopus 로고
    • Overcoming nucleoside analog chemoresistance of pancreatic cancer: a therapeutic challenge
    • Hung SW, Mody HR and Govindarajan R. Overcoming nucleoside analog chemoresistance of pancreatic cancer: a therapeutic challenge. Cancer letters. 2012; 320(2):138-149.
    • (2012) Cancer letters , vol.320 , Issue.2 , pp. 138-149
    • Hung, S.W.1    Mody, H.R.2    Govindarajan, R.3
  • 8
    • 34548455927 scopus 로고    scopus 로고
    • Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer
    • Hermann PC, Huber SL, Herrler T, Aicher A, Ellwart JW, Guba M, Bruns CJ and Heeschen C. Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer. Cell stem cell. 2007; 1(3):313-323.
    • (2007) Cell stem cell , vol.1 , Issue.3 , pp. 313-323
    • Hermann, P.C.1    Huber, S.L.2    Herrler, T.3    Aicher, A.4    Ellwart, J.W.5    Guba, M.6    Bruns, C.J.7    Heeschen, C.8
  • 9
    • 0035499267 scopus 로고    scopus 로고
    • Stem cells, cancer, and cancer stem cells
    • Reya T, Morrison SJ, Clarke MF and Weissman IL. Stem cells, cancer, and cancer stem cells. Nature. 2001; 414(6859):105-111.
    • (2001) Nature , vol.414 , Issue.6859 , pp. 105-111
    • Reya, T.1    Morrison, S.J.2    Clarke, M.F.3    Weissman, I.L.4
  • 14
    • 28244472369 scopus 로고    scopus 로고
    • Prospective identification of tumorigenic prostate cancer stem cells
    • Collins AT, Berry PA, Hyde C, Stower MJ and Maitland NJ. Prospective identification of tumorigenic prostate cancer stem cells. Cancer Res. 2005; 65(23):10946-10951.
    • (2005) Cancer Res , vol.65 , Issue.23 , pp. 10946-10951
    • Collins, A.T.1    Berry, P.A.2    Hyde, C.3    Stower, M.J.4    Maitland, N.J.5
  • 16
    • 84903768676 scopus 로고    scopus 로고
    • Tackling the cancer stem cells-what challenges do they pose?
    • Pattabiraman DR and Weinberg RA. Tackling the cancer stem cells-what challenges do they pose? Nat Rev Drug Discov. 2014; 13(7):497-512.
    • (2014) Nat Rev Drug Discov , vol.13 , Issue.7 , pp. 497-512
    • Pattabiraman, D.R.1    Weinberg, R.A.2
  • 18
    • 22244433866 scopus 로고    scopus 로고
    • Side population is enriched in tumorigenic, stem-like cancer cells, whereas ABCG2+ and ABCG2-cancer cells are similarly tumorigenic
    • Patrawala L, Calhoun T, Schneider-Broussard R, Zhou J, Claypool K and Tang DG. Side population is enriched in tumorigenic, stem-like cancer cells, whereas ABCG2+ and ABCG2-cancer cells are similarly tumorigenic. Cancer Res. 2005; 65(14):6207-6219.
    • (2005) Cancer Res , vol.65 , Issue.14 , pp. 6207-6219
    • Patrawala, L.1    Calhoun, T.2    Schneider-Broussard, R.3    Zhou, J.4    Claypool, K.5    Tang, D.G.6
  • 19
    • 34250306257 scopus 로고    scopus 로고
    • Side population in human lung cancer cell lines and tumors is enriched with stem-like cancer cells
    • Ho MM, Ng AV, Lam S and Hung JY. Side population in human lung cancer cell lines and tumors is enriched with stem-like cancer cells. Cancer Res. 2007; 67(10):4827-4833.
    • (2007) Cancer Res , vol.67 , Issue.10 , pp. 4827-4833
    • Ho, M.M.1    Ng, A.V.2    Lam, S.3    Hung, J.Y.4
  • 20
    • 84886743503 scopus 로고    scopus 로고
    • Lung cancer tumorigenicity and drug resistance are maintained through ALDH(hi)CD44(hi) tumor initiating cells
    • Liu J, Xiao Z, Wong SK, Tin VP, Ho KY, Wang J, Sham MH and Wong MP. Lung cancer tumorigenicity and drug resistance are maintained through ALDH(hi)CD44(hi) tumor initiating cells. Oncotarget. 2013; 4(10):1698-1711.
    • (2013) Oncotarget , vol.4 , Issue.10 , pp. 1698-1711
    • Liu, J.1    Xiao, Z.2    Wong, S.K.3    Tin, V.P.4    Ho, K.Y.5    Wang, J.6    Sham, M.H.7    Wong, M.P.8
  • 21
    • 84864536555 scopus 로고    scopus 로고
    • Metformin-induced preferential killing of breast cancer initiating CD44+CD24-/low cells is sufficient to overcome primary resistance to trastuzumab in HER2+ human breast cancer xenografts
    • Cufi S, Corominas-Faja B, Vazquez-Martin A, Oliveras-Ferraros C, Dorca J, Bosch-Barrera J, Martin-Castillo B and Menendez JA. Metformin-induced preferential killing of breast cancer initiating CD44+CD24-/low cells is sufficient to overcome primary resistance to trastuzumab in HER2+ human breast cancer xenografts. Oncotarget. 2012; 3(4):395-398.
    • (2012) Oncotarget , vol.3 , Issue.4 , pp. 395-398
    • Cufi, S.1    Corominas-Faja, B.2    Vazquez-Martin, A.3    Oliveras-Ferraros, C.4    Dorca, J.5    Bosch-Barrera, J.6    Martin-Castillo, B.7    Menendez, J.A.8
  • 22
    • 58149382597 scopus 로고    scopus 로고
    • CD44-specific antibody treatment and CD44 deficiency exert distinct effects on leukocyte recruitment in experimental arthritis
    • Hutas G, Bajnok E, Gal I, Finnegan A, Glant TT and Mikecz K. CD44-specific antibody treatment and CD44 deficiency exert distinct effects on leukocyte recruitment in experimental arthritis. Blood. 2008; 112(13):4999-5006.
    • (2008) Blood , vol.112 , Issue.13 , pp. 4999-5006
    • Hutas, G.1    Bajnok, E.2    Gal, I.3    Finnegan, A.4    Glant, T.T.5    Mikecz, K.6
  • 24
    • 0028487928 scopus 로고
    • Cytokeratins and mucins as molecular markers of cell differentiation and neoplastic transformation in the exocrine pancreas
    • Vila MR, Balague C and Real FX. Cytokeratins and mucins as molecular markers of cell differentiation and neoplastic transformation in the exocrine pancreas. Zentralblatt fur Pathologie. 1994; 140(3):225-235.
    • (1994) Zentralblatt fur Pathologie , vol.140 , Issue.3 , pp. 225-235
    • Vila, M.R.1    Balague, C.2    Real, F.X.3
  • 25
    • 84887516591 scopus 로고    scopus 로고
    • Inhibition of CXCL12/CXCR4 autocrine/paracrine loop reduces viability of human glioblastoma stem-like cells affecting self-renewal activity
    • Gatti M, Pattarozzi A, Bajetto A, Wurth R, Daga A, Fiaschi P, Zona G, Florio T and Barbieri F. Inhibition of CXCL12/CXCR4 autocrine/paracrine loop reduces viability of human glioblastoma stem-like cells affecting self-renewal activity. Toxicology. 2013; 314(2-3):209-220.
    • (2013) Toxicology , vol.314 , Issue.2-3 , pp. 209-220
    • Gatti, M.1    Pattarozzi, A.2    Bajetto, A.3    Wurth, R.4    Daga, A.5    Fiaschi, P.6    Zona, G.7    Florio, T.8    Barbieri, F.9
  • 29
    • 84865544325 scopus 로고    scopus 로고
    • EGF signalling pathway regulates colon cancer stem cell proliferation and apoptosis
    • Feng Y, Dai X, Li X, Wang H, Liu J, Zhang J, Du Y and Xia L. EGF signalling pathway regulates colon cancer stem cell proliferation and apoptosis. Cell proliferation. 2012; 45(5):413-419.
    • (2012) Cell proliferation , vol.45 , Issue.5 , pp. 413-419
    • Feng, Y.1    Dai, X.2    Li, X.3    Wang, H.4    Liu, J.5    Zhang, J.6    Du, Y.7    Xia, L.8
  • 30
    • 79953042645 scopus 로고    scopus 로고
    • CD44: can a cancer-initiating cell profit from an abundantly expressed molecule?
    • Zoller M. CD44: can a cancer-initiating cell profit from an abundantly expressed molecule? Nature reviews Cancer. 2011; 11(4):254-267.
    • (2011) Nature reviews Cancer , vol.11 , Issue.4 , pp. 254-267
    • Zoller, M.1
  • 31
    • 84859148851 scopus 로고    scopus 로고
    • CD44 Promotes Epithelial Mammary Gland Development and Exhibits Altered Localization during Cancer Progression
    • Louderbough JM, Brown JA, Nagle RB and Schroeder JA. CD44 Promotes Epithelial Mammary Gland Development and Exhibits Altered Localization during Cancer Progression. Genes & cancer. 2011; 2(8):771-781.
    • (2011) Genes & cancer , vol.2 , Issue.8 , pp. 771-781
    • Louderbough, J.M.1    Brown, J.A.2    Nagle, R.B.3    Schroeder, J.A.4
  • 33
    • 84903172149 scopus 로고    scopus 로고
    • Anti-CD44 mAb for the treatment of B-cell chronic lymphocytic leukemia and other hematological malignancies: evaluation of WO2013063498
    • D'Arena G, Calapai G and Deaglio S. Anti-CD44 mAb for the treatment of B-cell chronic lymphocytic leukemia and other hematological malignancies: evaluation of WO2013063498. Expert opinion on therapeutic patents. 2014; 24(7):821-828.
    • (2014) Expert opinion on therapeutic patents , vol.24 , Issue.7 , pp. 821-828
    • D'Arena, G.1    Calapai, G.2    Deaglio, S.3
  • 35
    • 52549087785 scopus 로고    scopus 로고
    • Cancer stem cells in solid tumours: accumulating evidence and unresolved questions
    • Visvader JE and Lindeman GJ. Cancer stem cells in solid tumours: accumulating evidence and unresolved questions. Nature reviews Cancer. 2008; 8(10):755-768.
    • (2008) Nature reviews Cancer , vol.8 , Issue.10 , pp. 755-768
    • Visvader, J.E.1    Lindeman, G.J.2
  • 36
    • 84862517728 scopus 로고    scopus 로고
    • Cancer stem cells: current status and evolving complexities
    • Visvader JE and Lindeman GJ. Cancer stem cells: current status and evolving complexities. Cell stem cell. 2012; 10(6):717-728.
    • (2012) Cell stem cell , vol.10 , Issue.6 , pp. 717-728
    • Visvader, J.E.1    Lindeman, G.J.2
  • 37
    • 84893637270 scopus 로고    scopus 로고
    • One mouse, one patient paradigm: New avatars of personalized cancer therapy
    • Malaney P, Nicosia SV and Dave V. One mouse, one patient paradigm: New avatars of personalized cancer therapy. Cancer letters. 2014; 344(1):1-12.
    • (2014) Cancer letters , vol.344 , Issue.1 , pp. 1-12
    • Malaney, P.1    Nicosia, S.V.2    Dave, V.3
  • 39
    • 84893860363 scopus 로고    scopus 로고
    • Tumor evolution in response to chemotherapy: phenotype versus genotype
    • Navin NE. Tumor evolution in response to chemotherapy: phenotype versus genotype. Cell reports. 2014; 6(3):417-419.
    • (2014) Cell reports , vol.6 , Issue.3 , pp. 417-419
    • Navin, N.E.1
  • 41
    • 0036513029 scopus 로고    scopus 로고
    • Oncogenic resistance to growth-limiting conditions
    • Blagosklonny MV. Oncogenic resistance to growth-limiting conditions. Nature reviews Cancer. 2002; 2(3):221-225.
    • (2002) Nature reviews Cancer , vol.2 , Issue.3 , pp. 221-225
    • Blagosklonny, M.V.1
  • 42
    • 29244479554 scopus 로고    scopus 로고
    • Why therapeutic response may not prolong the life of a cancer patient: selection for oncogenic resistance
    • Blagosklonny MV. Why therapeutic response may not prolong the life of a cancer patient: selection for oncogenic resistance. Cell cycle. 2005; 4(12):1693-1698.
    • (2005) Cell cycle , vol.4 , Issue.12 , pp. 1693-1698
    • Blagosklonny, M.V.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.