Beyond GWAS in COPD: Probing the landscape between gene-set associations, genome-wide associations and protein-protein interaction networks

Human Heredity

Volumn 78, Issue 3-4, 2014, Pages 131-139

  McDonald, Merry Lynn Noelle ^a   Mattheisen, Manuel ^a,e   Cho, Michael H ^a,b   Liu, Yang Yu ^a   Harshfield, Benjamin ^a   Hersh, Craig P ^a,b   Bakke, Per ^f   Gulsvik, Amund ^f   Lange, Christoph ^c   Beaty, Terri H ^d   Silverman, Edwin K ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^d JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^e AARHUS UNIVERSITY   (Denmark)

^f UNIVERSITY OF BERGEN   (Norway)

Author keywords

COPD; Disease module; Gene set association; Genome wide scan; Pathway association; Protein protein interaction network

Indexed keywords

INTERLEUKIN 7; UBIQUITIN PROTEIN LIGASE NEDD4;

ARTICLE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONSENSUS SEQUENCE; CONTROLLED STUDY; GENETIC ANALYSIS; GENETIC ASSOCIATION; HUMAN; MARKER GENE; PROTEIN PROTEIN INTERACTION; SYSTEMS BIOLOGY; AGED; GENETIC PREDISPOSITION; GENETICS; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; MIDDLE AGED; VERY ELDERLY;

AGED; AGED, 80 AND OVER; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HUMANS; MIDDLE AGED; PROTEIN INTERACTION MAPS; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE;

EID: 84928379383     PISSN: 00015652     EISSN: 14230062     Source Type: Journal    
DOI: 10.1159/000365589     Document Type: Article

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