Recent trends in testosterone testing, low testosterone levels, and testosterone treatment among Veterans

Andrology

Volumn 3, Issue 2, 2015, Pages 287-292

  Walsh, T J ^a   Shores, M M ^b   Fox, A E ^b   Moore, K P ^b   Forsberg, C W ^b   Kinsey, C E ^b   Heckbert, S R ^a   Zeliadt, S ^b   Thompson, M L ^a,b   Smith, N L ^b   Matsumoto, A M ^b,c  

^a UNIVERSITY OF WASHINGTON   (United States)

^b VA PUGET SOUND HEALTH CARE SYSTEM   (United States)

^c UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

Testosterone; Trends; Veterans

Indexed keywords

TESTOSTERONE;

ADULT; AGED; ANDROGEN THERAPY; ARTICLE; BREAST CANCER; CANCER DIAGNOSIS; CONTROLLED STUDY; HUMAN; MAJOR CLINICAL STUDY; MALE; PRESCRIPTION; PREVALENCE; PRIORITY JOURNAL; PROSTATE CANCER; TESTOSTERONE BLOOD LEVEL; VERY ELDERLY; VETERAN; HORMONE SUBSTITUTION; MIDDLE AGED; UNITED STATES;

ADULT; AGED; AGED, 80 AND OVER; HORMONE REPLACEMENT THERAPY; HUMANS; MALE; MIDDLE AGED; TESTOSTERONE; UNITED STATES; VETERANS;

EID: 84928306023     PISSN: 20472919     EISSN: 20472927     Source Type: Journal    
DOI: 10.1111/andr.12014     Document Type: Article

References (26)

1. Anawalt BD, Hotaling JM, Walsh TJ & Matsumoto AM. (2012) Performance of total testosterone measurement to predict free testosterone for the biochemical evaluation of male hypogonadism. J Urol 187, 1369-1373.
2. Araujo AB, O'Donnell AB, Brambilla DJ, Simpson WB, Longcope C, Matsumoto AM & McKinlay JB. (2004) Prevalence and incidence of androgen deficiency in middle-aged and older men: estimates from the Massachusetts Male Aging Study. J Clin Endocrinol Metab 89, 5920-5926.
3. Araujo AB, Esche GR, Kupelian V, O'Donnell AB, Travison TG, Williams RE, Clark RV & McKinlay JB. (2007) Prevalence of symptomatic androgen deficiency in men. J Clin Endocrinol Metab 92, 4241-4247.
4. Baillargeon J, Urban RJ, Ottenbacher KJ, Pierson KS & Goodwin JS. (2013) Trends in androgen prescribing in the United States, 2001 to 2011. JAMA Intern Med 173, 1465-1466.
5. Bhasin S, Cunningham GR, Hayes FJ, Matsumoto AM, Snyder PJ, Swerdloff RS & Montori VM & Endocrine Society Task Force. (2010) Testosterone therapy in men with androgen deficiency syndromes: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab 95, 2536-2559.
6. Corona G, Monami M, Boddi V, Cameron-Smith M, Fisher AD, de Vita G, Melani C, Balzi D, Sforza A, Forti G, Mannucci E & Maggi M. (2010) Low testosterone is associated with an increased risk of MACE lethality in subjects with erectile dysfunction. J Sex Med 7, 1557-1564.
7. Hall SA, Ranganathan G, Tinsley LJ, Lund JL, Kupelian V, Wittert GA, Kantoff PW, Morales A & Araujo AB. (2014) Population-based patterns of prescription androgen use, 1976-2008. Pharmacoepidemiol Drug Saf 23, 498-506.
8. Handelsman DJ. (2013) Global trends in testosterone prescribing, 2000-2011: expanding the spectrum of prescription drug misuse. Med J Aust 199, 548-551.
9. Haring R, Nauck M, Volzke H, Endlich K, Lendeckel U, Friedrich N, Dorr M, Rettig R, Kroemer HK & Wallaschofski H. (2011) Low serum testosterone is associated with increased mortality in men with stage 3 or greater nephropathy. Am J Nephrol 33, 209-217.
10. Haring R, John U, Volzke H, Nauck M, Dorr M, Felix SB & Wallaschofski H. (2012) Low testosterone concentrations in men contribute to the gender gap in cardiovascular morbidity and mortality. Gend Med 9, 557-568.
11. Harman SM, Metter EJ, Tobin JD, Pearson J & Blackman MR & Baltimore Longitudinal Study of Aging. (2001) Longitudinal effects of aging on serum total and free testosterone levels in healthy men. Baltimore Longitudinal Study of Aging. J Clin Endocrinol Metab 86, 724-731.
12. Hyde Z, Norman PE, Flicker L, Hankey GJ, Almeida OP, McCaul KA, Chubb SA & Yeap BB. (2012) Low free testosterone predicts mortality from cardiovascular disease but not other causes: the Health in Men Study. J Clin Endocrinol Metab 97, 179-189.
13. Khaw KT, Dowsett M, Folkerd E, Bingham S, Wareham N, Luben R, Welch A & Day N. (2007) Endogenous testosterone and mortality due to all causes, cardiovascular disease, and cancer in men: European prospective investigation into cancer in Norfolk (EPIC-Norfolk) Prospective Population Study. Circulation 116, 2694-2701.
14. Kramarow EA & Pastor PN. (2012) The health of male Veterans and nonVeterans aged 25-64: United States, 2007-2010. NCHS Data Brief 101, 1-7.
15. Kyriazis J, Tzanakis I, Stylianou K, Katsipi I, Moisiadis D, Papadaki A, Mavroeidi V, Kagia S, Karkavitsas N & Daphnis E. (2011) Low serum testosterone, arterial stiffness and mortality in male haemodialysis patients. Nephrol Dial Transplant 26, 2971-2977.
16. Layton JB, Li D, Meier CR, Sharpless J, Sturmer T, Jick SS & Brookhart MA. (2014) Testosterone lab testing and initiation in the United Kingdom and the United States, 2000-2011. J Clin Endocrinol Metab 99, 835-842.
17. Malkin CJ, Pugh PJ, Morris PD, Asif S, Jones TH & Channer KS. (2010) Low serum testosterone and increased mortality in men with coronary heart disease. Heart 96, 1821-1825.
18. Ponikowska B, Jankowska EA, Maj J, Wegrzynowska-Teodorczyk K, Biel B, Reczuch K, Borodulin-Nadzieja L, Banasiak W & Ponikowski P. (2010) Gonadal and adrenal androgen deficiencies as independent predictors of increased cardiovascular mortality in men with type II diabetes mellitus and stable coronary artery disease. Int J Cardiol 143, 343-348.
19. Schneider HJ, Wallaschofski H, Volzke H, Markus MR, Doerr M, Felix SB, Nauck M & Friedrich N. (2012) Incremental effects of endocrine and metabolic biomarkers and abdominal obesity on cardiovascular mortality prediction. PLoS ONE 7, e33084.
20. Shores MM, Sloan KL, Matsumoto AM, Moceri VM, Felker B & Kivlahan DR. (2004) Increased incidence of diagnosed depressive illness in hypogonadal older men. Arch Gen Psychiatry 61, 162-167.
21. Shores MM, Matsumoto AM, Sloan KL & Kivlahan DR. (2006) Low serum testosterone and mortality in male veterans. Arch Intern Med 166, 1660-1665.
22. Shores MM, Smith NL, Forsberg CW, Anawalt BD & Matsumoto AM. (2012) Testosterone treatment and mortality in men with low testosterone levels. J Clin Endocrinol Metab 97, 2050-2058.
23. Vermeulen A, Verdonck L & Kaufman JM. (1999) A critical evaluation of simple methods for the estimation of free testosterone in serum. J Clin Endocrinol Metab 84, 3666-3672.
24. Vikan T, Schirmer H, Njolstad I & Svartberg J. (2009) Endogenous sex hormones and the prospective association with cardiovascular disease and mortality in men: the Tromsø Study. Eur J Endocrinol 161, 435-442.
25. Wang C, Nieschlag E, Swerdloff R, Behre HM, Hellstrom WJ, Gooren LJ, Kaufman JM, Legros JJ, Lunenfeld B, Morales A, Morley JE, Schulman C, Thompson IM, Weidner W & Wu FCW. (2009) Investigation, treatment and monitoring of late-onset hypogonadism in males. J Androl 30, 1-9.
26. Wu FC, Tajar A, Beynon JM, Pye SR, Silman AJ, Finn JD, O'Neill TW, Bartfai G, Casanueva FF, Forti G, Giwercman A, Han TS, Kula K, Lean ME, Pendleton N, Punab M, Boonen S, Vanderschueren D, Labrie F & Huhtaniemi IT & EMAS Study Group. (2010) Identification of late-onset hypogonadism in middle-aged and elderly men. N Engl J Med 363, 123-135.