Reduction of inappropriate exit prescriptions for proton pump inhibitors: A before-after study using education paired with a web-based quality-improvement tool

Journal of Hospital Medicine

Volumn 10, Issue 5, 2015, Pages 281-286

  Mcdonald, Emily G ^a,b   Jones, Janelle ^a   Green, Laurence ^a,b   Jayaraman, Dev ^a,b   Lee, Todd C ^a,b  

^a MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

^b MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANTITHROMBOCYTIC AGENT; BISPHOSPHONIC ACID DERIVATIVE; CORTICOSTEROID; NONSTEROID ANTIINFLAMMATORY AGENT; PROTON PUMP INHIBITOR;

ADULT; AGED; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG INDICATION; EVIDENCE BASED PRACTICE; FEMALE; HOSPITAL ADMISSION; HOSPITAL DISCHARGE; HOSPITALIZATION; HUMAN; INAPPROPRIATE PRESCRIBING; INTERNET; MAJOR CLINICAL STUDY; MALE; PATIENT EDUCATION; PRIORITY JOURNAL; TOTAL QUALITY MANAGEMENT; VERY ELDERLY; EPIDEMIOLOGY; IN SERVICE TRAINING; MIDDLE AGED; PREVENTION AND CONTROL; PROCEDURES; STATISTICS AND NUMERICAL DATA; UNIVERSITY HOSPITAL;

AGED; AGED, 80 AND OVER; CONTROLLED BEFORE-AFTER STUDIES; FEMALE; HOSPITALIZATION; HOSPITALS, UNIVERSITY; HUMANS; INAPPROPRIATE PRESCRIBING; INSERVICE TRAINING; INTERNET; MALE; MIDDLE AGED; PROTON PUMP INHIBITORS;

EID: 84928280246     PISSN: 15535592     EISSN: 15535606     Source Type: Journal    
DOI: 10.1002/jhm.2330     Document Type: Article

References (32)

1. IMS Institute for Healthcare Informatics. Medicine Use and Shifting Costs of Healthcare. 2014. Available at: http://www.imshealth.com/deployedfiles/imshealth/Global/Content/Corporate/IMS%20Health%20Institute/Reports/Secure/IIHI_US_Use_of_Meds_for_2013.pdf. Accessed September 26, 2014.
2. Johansen ME, Huerta TR, Richardson CR. National use of proton pump inhibitors from 2007 to 2011. JAMA Intern Med. 2014;174(11):1856-1858.
3. Health Canada. Proton Pump Inhibitors (antacids): Possible Risk of Clostridium difficile-Associated Diarrhea. 2012. Available at: http://www.healthycanadians.gc.ca/recall-alert-rappel-avis/hc-sc/2012/13651a-eng.php. Accessed February 16, 2015.
4. Health Canada. Proton Pump Inhibitors: Hypomagnesemia Accompanied by Hypocalcemia and Hypokalemia. 2011. Available at: http://www.hc-sc.gc.ca/dhp-mps/medeff/bulletin/carn-bcei_v21n3-eng.php#_Proton_pump_inhibitors. Accessed February 16, 2015.
5. US Food and Drug Administration. FDA Drug Safety Communication: Possible Increased Risk of Fractures of the Hip, Wrist, and Spine With the Use of Proton Pump Inhibitors. 2012. Available at: http://www.fda.gov/Drugs/DrugSafety/PostmarketDrugSafetyInformationforPatientsandProviders/ucm213206.htm. Accessed February 15, 2015.
6. US Food and Drug Administration. FDA Drug Safety Communication: Clostridium difficile-Associated Diarrhea Can Be Associated With Stomach Acid Drugs Known as Proton Pump Inhibitors (PPIs). 2012. Available at: http://www.fda.gov/drugs/drugsafety/ucm290510.htm. Accessed February 15, 2015.
7. Johnstone J, Nerenberg K, Loeb M. Meta-analysis: proton pump inhibitor use and the risk of community-acquired pneumonia. Aliment Pharmacol Ther. 2010;31(11):1165-1177.
8. Maggio M, Corsonello A, Ceda GP, et al. Proton pump inhibitors and risk of 1-year mortality and rehospitalization in older patients discharged from acute care hospitals. JAMA Intern Med. 2013;173(7):518-523.
9. Herzig SJ, Howell MD, Ngo LH, Marcantonio ER. Acid-suppressive medication use and the risk for hospital-acquired pneumonia. JAMA. 2009;301(20):2120-2128.
10. Corsonello A, Maggio M, Fusco S, et al. Proton pump inhibitors and functional decline in older adults discharged from acute care hospitals. J Am Geriatr Soc. 2014;62(6):1110-1115.
11. Albugeaey M, Alfaraj N, Garb J, Seiler A, Lagu T. Do hospitalists overuse proton pump inhibitors? Data from a contemporary cohort. J Hosp Med. 2014;9(11):731-733.
12. Reid M, Keniston A, Heller JC, Miller M, Medvedev S, Albert RK. Inappropriate prescribing of proton pump inhibitors in hospitalized patients. J Hosp Med. 2012;7(5):421-425.
13. Ladd AM, Panagopoulos G, Cohen J, Mar N, Graham R. Potential costs of inappropriate use of proton pump inhibitors. Am J Med Sci. 2014;347(6):446-451.
14. Zink DA, Pohlman M, Barnes M, Cannon ME. Long-term use of acid suppression started inappropriately during hospitalization. Aliment Pharmacol Ther. 2005;21(10):1203-1209.
15. Grant K, Al-Adhami N, Tordoff J, Livesey J, Barbezat G, Reith D. Continuation of proton pump inhibitors from hospital to community. Pharm World Sci. 2006;28(4):189-193.
16. Breu AC, Allen-Dicker J, Mueller S, Palamara K, Hinami K, Herzig SJ. Hospitalist and primary care physician perspectives on medication management of chronic conditions for hospitalized patients. J Hosp Med. 2014;9(5):303-309.
17. Sung JJ, Chung SC, Ling TK, et al. Antibacterial treatment of gastric ulcers associated with Helicobacter pylori. N Engl J Med. 1995;332(3):139-142.
18. Lau JY, Sung JJ, Lee KK, et al. Effect of intravenous omeprazole on recurrent bleeding after endoscopic treatment of bleeding peptic ulcers. N Engl J Med. 2000;343(5):310-316.
19. Lai KC, Lam SK, Chu KM, et al. Lansoprazole for the prevention of recurrences of ulcer complications from long-term low-dose aspirin use. N Engl J Med. 2002;346(26):2033-2038.
20. Chey WD, Wong BCY. American College of Gastroenterology guideline on the management of Helicobacter pylori infection. Am J Gastroenterol. 2007;102(8):1808-1825.
21. Lanza FL, Chan FKL, Quigley EMM. Guidelines for prevention of NSAID-related ulcer complications. Am J Gastroenterol. 2009;104(3):728-738.
22. Rostom A, Moayyedi P, Hunt R, Canadian consensus guidelines on long-term nonsteroidal anti-inflammatory drug therapy and the need for gastroprotection: benefits versus risks. Aliment Pharmacol Ther. 2009;29(5):481-496.
23. van Vliet EP, Steyerberg EW, Otten HJ, et al., The effects of guideline implementation for proton pump inhibitor prescription on two pulmonary medicine wards. Aliment Pharmacol Ther. 2009;29(2):213-221.
24. Wagner AK, Soumerai SB, Zhang F, Ross-Degnan D. Segmented regression analysis of interrupted time series studies in medication use research. J Clin Pharm Ther. 2002;27(4):299-309.
25. Nardino RJ, Vender RJ, Herbert PN. Overuse of acid-suppressive therapy in hospitalized patients. Am J Gastroenterol. 2000;95(11):3118-3122.
26. Mat Saad AZ, Collins N, Lobo MM, O'Connor HJ. Proton pump inhibitors: a survey of prescribing in an Irish general hospital. Int J Clin Pract. 2005;59(1):31-34.
27. Naunton M, Peterson GM, Bleasel MD. Overuse of proton pump inhibitors. J Clin Pharm Ther. 2000;25(5):333-340.
28. Pasina L, Nobili A, Tettamanti M, et al. Prevalence and appropriateness of drug prescriptions for peptic ulcer and gastro-esophageal reflux disease in a cohort of hospitalized elderly. Eur J Intern Med. 2011;22(2):205-210.
29. Batuwitage BT, Kingham JG, Morgan NE, Bartlett RL. Inappropriate prescribing of proton pump inhibitors in primary care. Postgrad Med J. 2007;83(975):66-68.
30. Hamzat H, Sun H, Ford JC, Macleod J, Soiza RL, Mangoni AA. Inappropriate prescribing of proton pump inhibitors in older patients: effects of an educational strategy. Drugs Aging. 2012;29(8):681-690.
31. Chui D, Young F, Tejani AM, Dillon EC. Impact of academic detailing on proton pump inhibitor prescribing behaviour in a community hospital. Can Pharm J (Ott). 2011;144(2):66-71.
32. Gupta R, Marshall J, Munoz JC, Kottoor R, Jamal MM, Vega KJ. Decreased acid suppression therapy overuse after education and medication reconciliation. Int J Clin Pract. 2013;67(1):60-65.