Prior pneumococcal and influenza vaccinations and in-hospital outcomes for community-acquired pneumonia in elderly veterans

Journal of Hospital Medicine

Volumn 10, Issue 5, 2015, Pages 287-293

  Li, Chenghui ^a,b   Gubbins, Paul O ^c   Chen, Guoqing J ^d  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^b CENTRAL ARKANSAS VETERANS HEALTHCARE SYSTEM   (United States)

^c UNIVERSITY OF MISSOURI KANSAS CITY   (United States)

^d UNIVERSITY OF KANSAS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGED; ARTICLE; BACTEREMIA; COMMUNITY ACQUIRED PNEUMONIA; FEMALE; HUMAN; INFLUENZA VACCINATION; LENGTH OF STAY; MAJOR CLINICAL STUDY; MALE; MORTALITY; PNEUMOCOCCAL VACCINATION; PRIORITY JOURNAL; RETROSPECTIVE STUDY; VACCINATION; VERY ELDERLY; COMMUNITY-ACQUIRED INFECTIONS; ODDS RATIO; PNEUMONIA, PNEUMOCOCCAL; PUBLIC HOSPITAL; SEVERITY OF ILLNESS INDEX; SOCIOECONOMICS;

INFLUENZA VACCINE; PNEUMOCOCCUS VACCINE;

AGED; AGED, 80 AND OVER; COMMUNITY-ACQUIRED INFECTIONS; FEMALE; HOSPITAL MORTALITY; HOSPITALS, VETERANS; HUMANS; INFLUENZA VACCINES; LENGTH OF STAY; MALE; ODDS RATIO; PNEUMOCOCCAL VACCINES; PNEUMONIA, PNEUMOCOCCAL; RETROSPECTIVE STUDIES; SEVERITY OF ILLNESS INDEX; SOCIOECONOMIC FACTORS;

EID: 84928276514     PISSN: 15535592     EISSN: 15535606     Source Type: Journal    
DOI: 10.1002/jhm.2328     Document Type: Article

References (45)

1. Stupka JE, Mortensen EM, Anzueto A, Restrep MI. Community-acquired pneumonia in elderly patients. Aging Health. 2009;5(6):763-774.
2. CDC/NCHS National Hospital Discharge Survey, 2010. Number of discharges from short-stay hospitals, by first-listed diagnosis and age: United States, 2010. National Center for Health Statistics. Available at: http://www.cdc.gov/nchs/data/nhds/3firstlisted/2010first3_numberage.pdf. Accessed July 14, 2014.
3. Fung HB, Monteagudo-Chu MO. Community-acquired pneumonia in the elderly. Am J Geriatr Pharmacother. 2010;8(1):47-62.
4. Jackson LA, Neuzil KM, Yu O, et al. Effectiveness of pneumococcal polysaccharide vaccine in older adults. N Engl J Med. 2003;348:1747-1754.
5. Jackson LA, Janoff EN. Pneumococcal vaccination of elderly adults: new paradigms for protection. Clin Infect Dis. 2008;47(10):1328-1338.
6. Melegaro A, Edmunds WJ. The 23-valent pneumococcal polysaccharide vaccine. Part 1. Efficacy of PPV in the elderly: a comparison of meta-analysis. Eur J Epidemiol. 2004;19:353-363.
7. Moberley S, Holden J, Tatham DP, Andrews RM. Vaccines for preventing pneumococcal infection in adults. Cochrane Database Syst Rev. 2008;(1):CD000422.
8. Huss A, Scott P, Stuck AE, Trotter C, Egger M. Efficacy of pneumococcal vaccination in adults: a meta-analysis. CMAJ. 2009;180(1):48-58.
9. Fisman DN, Abrutyn E, Spaude KA, Kim A, Kirchner C, Daley J. Prior pneumococcal vaccination is associated with reduced death, complications, and length of stay among hospitalized adults with community-acquired pneumonia. Clin Infect Dis. 2006;42:1093-1101.
10. Mykietiuk A, Carratalà J, Domínguez A, et al. Effect of prior pneumococcal vaccination on clinical outcome of hospitalized adults with community-acquired pneumococcal pneumonia. Eur J Clin Microbiol Infect Dis. 2006;25:257-462.
11. Johnstone J, Marrie T, Eurich D, Majumdar S. Effect of pneumococcal vaccination in hospitalized adults with community-acquired pneumonia. Arch Intern Med. 2007;167:1938-1943.
12. Spaude KA, Abrutyn E, Kirchner C, Kim A, Deley J, Fisman DN. Influenza vaccination and risk of mortality among adults hospitalized with community-acquired pneumonia. Arch Intern Med. 2007;167:53-59.
13. Jefferson T, Rivetti D, Rivetti A, Rudin M, DiPietrantanj C, Demicheli V. Efficacy and effectiveness of influenza vaccines in elderly people: a systematic review. Lancet. 2005;366:1165-1174.
14. Nichol KL, Nordin JD, Nelson DB, Mullooly JP, Hak E. Effectiveness of influenza vaccine in the community-dwelling elderly. N Engl J Med. 2007;357:1373-1381.
15. VIReC Research User Guide: FY2002 VHA Medical SAS Inpatient Datasets. Hines, IL: Veterans Affairs Information Resource Center; 2003.
16. Immunization Information Systems, Centers for Disease Control and Prevention. CPT codes mapped to CVX codes. Available at: http://www2a.cdc.gov/vaccines/iis/iisstandards/vaccines.asp?rpt=cpt. Accessed December 2, 2014.
17. Centers for Disease Control and Prevention. Pneumococcal polysaccharide vaccine information statement. Available at: http://www.cdc.gov/vaccines/hcp/vis/vis-statements/ppv.html. Accessed December 2, 2014.
18. Shapiro ED, Berg AT, Austrian R, et al. The protective efficacy of polyvalent pneumococcal polysaccharide vaccine. N Engl J Med. 1991;325:1453-1460.
19. Deyo RA, Cherkin DC, Ciol MA. Adapting a clinical comorbidity index for use with ICD-9-CM Administrative Databases. J Clin Epidemiol. 1992;45(6):613-619.
20. Long JA, Bamba MI, Ling B, Shea JA. Missing race/ethnicity data in Veterans Health Administration based disparities research: a systematic review. J Health Care Poor Underserved. 2006;17:128-140.
21. Escobar GJ, Fireman BH, Palen TE, et al. Risk adjusting community-acquired pneumonia hospital outcomes using automated databases. Am J Manag Care. 2008;14(3):158-166.
22. Fine MJ, Auble TE, Yealy DM, et al. A prediction rule to identify low-risk patients with community-acquired pneumonia. N Engl J Med. 1997;336:243-250.
23. Austin PC, Rothwell DM, Tu JV. A comparison of statistical modeling strategies for analyzing length of stay after CABG surgery. Health Serv Outcomes Res Methodol. 2002;3:107-133.
24. Kosanke J, Bergstralh E. GMATCH SAS macro. Available at: http://www.mayo.edu/research/documents/gmatchsas/DOC-10027248. Accessed December 2, 2014.
25. Faries D, Leon A, Haro J, Obenchain R. Analysis of Observational Health Care Data Using SAS. Cary, NC: SAS Institute; 2010.
26. Schenkein JG, Park S, Nahm MH. Pneumococcal vaccination in older adults induces antibodies with low opsonic capacity and reduced antibody potency. Vaccine. 2008;26:5521-5526.
27. Lee H, Nahm MH, Kim KH. The effect of age on the response to the pneumococcal polysaccharide vaccine. BMC Infect Dis. 2010;10:60.
28. Park S, Nahm MH. Older adults have a low capacity to opsonize pneumococci due to low IgM antibody response to pneumococcal vaccinations. Infect Immun. 2011;79(1):314-320.
29. Johnstone J, Eurich DT, Minhas JK, Marrie TJ, Majumda SR. Impact of the pneumococcal vaccine on long-term morbidity and mortality of adults at high risk for pneumonia. Clin Infect Dis. 2010;51(1):15-22.
30. Simonsen L, Taylor RJ, Schuck-Pain C, Lutig R, Haber M, Klugman KP. Effect of 13-valent pneumococcal conjugate vaccine on admissions to hospital 2 years after its introduction in the USA: a time series analysis. Lancet Respir Med. 2014;2(5):387-394.
31. American Academy of Family Physicians. ACIP recommends routine PCV13 immunization for adults 65 and older. Available at: http://www.aafp.org/news/health-of-the-public/20140827pcv13vote.html. Accessed December 2, 2012.
32. Jackson LA, Neuzil KM, Thompson WW, et al. The burden of community-acquired pneumonia in seniors: results of a population-based study. Clin Infect Dis. 2004;39:1642-1650.
33. Christensen JS, Jensen TG, Kolmos HJ, et al. Bacteremia with Streptococcus pneumoniae: sepsis and other risk factors for 30-day mortality-a hospital-based cohort study. Eur J Clin Microbiol Infect Dis. 2012;13(10):2719-2725.
34. Fry Am, Shay DK, Holman RC, Curns AT, Anderson LJ. Trends in hospitalizations for pneumonia among persons aged 65 years or older in the United States, 1988-2002. JAMA. 2005;294(21):2712-2719.
35. Wiemken TL, Carrico RM, Klein SL, et al. The effectiveness of the polysaccharide pneumococcal vaccine for the prevention of hospitalizations due to Streptococcus pneumoniae community-acquired pneumonia in the elderly differs between the sexes: results from the Community-Acquired Pneumonia Organization (CAPO) international cohort study. Vaccine. 2014;17:32(19):2198-2203.
36. Jha Ak, Wright SM, Perlin JB. Performance measures, vaccinations, and pneumonia rates among high-risk patients in Veterans Administration health care. Am J Public Health. 2007;97(12):2167-2172.
37. Chi RC, Reber GE, Neuzil KM. Influenza and pneumococcal vaccination in older veterans: results from the Behavioral Risk Factor Surveillance System. J Am Geriatr Soc. 2006;54:217-223.
38. Nichol KL, Margolis KL, Wuorenma J, Von Sternberg T. The efficacy and cost effectiveness of vaccination against influenza among elderly persons living in the community. N Engl J Med. 1994;331:778-784.
39. Nichol KL, Baken L, Wuorenma J, Nelson A. The health and economic benefits associated with pneumococcal vaccination of elderly persons with chronic lung disease. Arch Intern Med. 1999;159:2437-2442.
40. Wong-Beringer A, Brodetsky E, Quist R. Pneumococcal vaccination in hospitalized elderly patients: role of the pharmacist. Pharmacotherapy. 2003;2(23):199-208.
41. Aronsky D, Haug PJ, Lagor C, Dean NC. Accuracy of administrative data for identifying patients with pneumonia. Am J Med Qual. 2005;30:319-328.
42. van de Garde EM, Oosterheert JJ, Bonten M, Kaplan RC, Leufkens HG. International classification of diseases codes showed modest sensitivity for detecting community-acquired pneumonia. J Clin Epidemiol. 2007;60(8):834-838.
43. Ament A, Baltussen R, Duru G, et al. Cost-effectiveness of pneumococcal vaccination of older people: a study in 5 western European countries. Clin Infect Dis. 2000;31:444-450.
44. Evers SM, Ament AJ, Colombo GL, et al. Cost-effectiveness of pneumococcal vaccination for prevention of invasive pneumococcal disease in the elderly: an update for 10 Western European countries. Eur J Clin Microbiol Infect Dis. 2007;26(8):531-540.
45. Maruyama T, Taguchi O, Niederman MS, et al. Efficacy of 23-valent pneumococcal vaccine in preventing pneumonia and improving survival in nursing home residents: double blind, randomised and placebo controlled trial. BMJ. 2010;340:c1004.