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Volumn 16, Issue 1, 2015, Pages

Sexually dimorphic gene expression emerges with embryonic genome activation and is dynamic throughout development

Author keywords

Chromatin; Development; Epigenetics; Gene expression; Mammalian; Mouse; Pre implantation embryo; Sex specific; Sexual dimorphism

Indexed keywords

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DEVELOPMENTAL STAGE; EMBRYO; EPIGENETICS; FEMALE; FETUS; GENE ACTIVATION; GENE EXPRESSION; GENETIC ANALYSIS; GENETIC CONSERVATION; GENETIC TRANSCRIPTION; GESTATIONAL AGE; HISTONE MODIFICATION; LIVER; MALE; MOUSE; NONHUMAN; PLURIPOTENT STEM CELL; PREIMPLANTATION EMBRYO; RNA SEQUENCE; SEX DIFFERENCE; X CHROMOSOME LINKAGE; ANIMAL; EMBRYO DEVELOPMENT; GENE EXPRESSION REGULATION; GENETICS; GENOME; MAMMALIAN EMBRYO; PREGNANCY; SEX CHROMOSOME; SEXUAL DEVELOPMENT;

EID: 84928250444     PISSN: None     EISSN: 14712164     Source Type: Journal    
DOI: 10.1186/s12864-015-1506-4     Document Type: Article
Times cited : (77)

References (52)
  • 1
    • 70350046265 scopus 로고    scopus 로고
    • Genetic and molecular insights into the development and evolution of sexual dimorphism
    • Williams TM, Carroll SB. Genetic and molecular insights into the development and evolution of sexual dimorphism. Nat Rev Genet. 2009;10(11):797-804.
    • (2009) Nat Rev Genet , vol.10 , Issue.11 , pp. 797-804
    • Williams, T.M.1    Carroll, S.B.2
  • 2
    • 77951794067 scopus 로고    scopus 로고
    • Global survey of escape from X inactivation by RNA-sequencing in mouse
    • Yang F, Babak T, Shendure J, Disteche CM. Global survey of escape from X inactivation by RNA-sequencing in mouse. Genome Res. 2010;20(5):614-22.
    • (2010) Genome Res , vol.20 , Issue.5 , pp. 614-622
    • Yang, F.1    Babak, T.2    Shendure, J.3    Disteche, C.M.4
  • 3
    • 56549099067 scopus 로고    scopus 로고
    • Sex-specific genetic architecture of human disease
    • Ober C, Loisel DA, Gilad Y. Sex-specific genetic architecture of human disease. Nat Rev Genet. 2008;9(12):911-22.
    • (2008) Nat Rev Genet , vol.9 , Issue.12 , pp. 911-922
    • Ober, C.1    Loisel, D.A.2    Gilad, Y.3
  • 5
    • 84859504942 scopus 로고    scopus 로고
    • Sex differences in disease risk from reported genome-wide association study findings
    • Liu LY, Schaub MA, Sirota M, Butte AJ. Sex differences in disease risk from reported genome-wide association study findings. Hum Genet. 2012;131(3):353-64.
    • (2012) Hum Genet , vol.131 , Issue.3 , pp. 353-364
    • Liu, L.Y.1    Schaub, M.A.2    Sirota, M.3    Butte, A.J.4
  • 6
    • 0037109668 scopus 로고    scopus 로고
    • A model system for study of sex chromosome effects on sexually dimorphic neural and behavioral traits
    • De Vries GJ, Rissman EF, Simerly RB, Yang LY, Scordalakes EM, Auger CJ, et al. A model system for study of sex chromosome effects on sexually dimorphic neural and behavioral traits. J Neurosci. 2002;22(20):9005-14.
    • (2002) J Neurosci , vol.22 , Issue.20 , pp. 9005-9014
    • Vries, G.J.1    Rissman, E.F.2    Simerly, R.B.3    Yang, L.Y.4    Scordalakes, E.M.5    Auger, C.J.6
  • 7
    • 84874618686 scopus 로고    scopus 로고
    • X and Y chromosome complement influence adiposity and metabolism in mice
    • Chen X, McClusky R, Itoh Y, Reue K, Arnold AP. X and Y chromosome complement influence adiposity and metabolism in mice. Endocrinology. 2013;154(3):1092-104.
    • (2013) Endocrinology , vol.154 , Issue.3 , pp. 1092-1104
    • Chen, X.1    McClusky, R.2    Itoh, Y.3    Reue, K.4    Arnold, A.P.5
  • 8
    • 84875819026 scopus 로고    scopus 로고
    • Gonadal- and sex-chromosome-dependent sex differences in the circadian system
    • Kuljis DA, Loh DH, Truong D, Vosko AM, Ong ML, McClusky R, et al. Gonadal- and sex-chromosome-dependent sex differences in the circadian system. Endocrinology. 2013;154(4):1501-12.
    • (2013) Endocrinology , vol.154 , Issue.4 , pp. 1501-1512
    • Kuljis, D.A.1    Loh, D.H.2    Truong, D.3    Vosko, A.M.4    Ong, M.L.5    McClusky, R.6
  • 9
    • 84873036238 scopus 로고    scopus 로고
    • Sex differences in developmental programming models
    • Aiken CE, Ozanne SE. Sex differences in developmental programming models. Reproduction. 2013;145(1):R1-13.
    • (2013) Reproduction , vol.145 , Issue.1 , pp. R1-13
    • Aiken, C.E.1    Ozanne, S.E.2
  • 10
    • 30944440423 scopus 로고    scopus 로고
    • Comparison of gene expression in male and female mouse blastocysts revealed imprinting of the X-linked gene, Rhox5/Pem, at preimplantation stages
    • Kobayashi S, Isotani A, Mise N, Yamamoto M, Fujihara Y, Kaseda K, et al. Comparison of gene expression in male and female mouse blastocysts revealed imprinting of the X-linked gene, Rhox5/Pem, at preimplantation stages. Curr Biol. 2006;16(2):166-72.
    • (2006) Curr Biol , vol.16 , Issue.2 , pp. 166-172
    • Kobayashi, S.1    Isotani, A.2    Mise, N.3    Yamamoto, M.4    Fujihara, Y.5    Kaseda, K.6
  • 11
    • 77649268853 scopus 로고    scopus 로고
    • Sex determines the expression level of one third of the actively expressed genes in bovine blastocysts
    • Bermejo-Alvarez P, Rizos D, Rath D, Lonergan P, Gutierrez-Adan A. Sex determines the expression level of one third of the actively expressed genes in bovine blastocysts. Proc Natl Acad Sci U S A. 2010;107(8):3394-9.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , Issue.8 , pp. 3394-3399
    • Bermejo-Alvarez, P.1    Rizos, D.2    Rath, D.3    Lonergan, P.4    Gutierrez-Adan, A.5
  • 12
    • 84903751477 scopus 로고    scopus 로고
    • In Vitro Fertilization Affects Growth and Glucose Metabolism in a Sex-Specific Manner in an Outbred Mouse Model
    • Donjacour A, Liu X, Lin W, Simbulan R, Rinaudo P. In Vitro Fertilization Affects Growth and Glucose Metabolism in a Sex-Specific Manner in an Outbred Mouse Model. Biol Reprod. 2014;90(4):80-90.
    • (2014) Biol Reprod , vol.90 , Issue.4 , pp. 80-90
    • Donjacour, A.1    Liu, X.2    Lin, W.3    Simbulan, R.4    Rinaudo, P.5
  • 13
    • 33644848689 scopus 로고    scopus 로고
    • Roadmap to embryo implantation: clues from mouse models
    • Wang H, Dey SK. Roadmap to embryo implantation: clues from mouse models. Nat Rev Genet. 2006;7(3):185-99.
    • (2006) Nat Rev Genet , vol.7 , Issue.3 , pp. 185-199
    • Wang, H.1    Dey, S.K.2
  • 14
    • 84892179132 scopus 로고    scopus 로고
    • Single-cell RNA-seq reveals dynamic, random monoallelic gene expression in mammalian cells
    • Deng Q, Ramskold D, Reinius B, Sandberg R. Single-cell RNA-seq reveals dynamic, random monoallelic gene expression in mammalian cells. Science. 2014;343(6167):193-6.
    • (2014) Science , vol.343 , Issue.6167 , pp. 193-196
    • Deng, Q.1    Ramskold, D.2    Reinius, B.3    Sandberg, R.4
  • 15
    • 84890723656 scopus 로고    scopus 로고
    • Inferring the choreography of parental genomes during fertilization from ultralarge-scale whole-transcriptome analysis
    • Park SJ, Komata M, Inoue F, Yamada K, Nakai K, Ohsugi M, et al. Inferring the choreography of parental genomes during fertilization from ultralarge-scale whole-transcriptome analysis. Genes Dev. 2013;27(24):2736-48.
    • (2013) Genes Dev , vol.27 , Issue.24 , pp. 2736-2748
    • Park, S.J.1    Komata, M.2    Inoue, F.3    Yamada, K.4    Nakai, K.5    Ohsugi, M.6
  • 16
    • 78751698195 scopus 로고    scopus 로고
    • Ftx is a non-coding RNA which affects Xist expression and chromatin structure within the X-inactivation center region
    • Chureau C, Chantalat S, Romito A, Galvani A, Duret L, Avner P, et al. Ftx is a non-coding RNA which affects Xist expression and chromatin structure within the X-inactivation center region. Hum Mol Genet. 2011;20(4):705-18.
    • (2011) Hum Mol Genet , vol.20 , Issue.4 , pp. 705-718
    • Chureau, C.1    Chantalat, S.2    Romito, A.3    Galvani, A.4    Duret, L.5    Avner, P.6
  • 17
    • 0035152339 scopus 로고    scopus 로고
    • Genetic and developmental analysis of X-inactivation in interspecific hybrid mice suggests a role for the Y chromosome in placental dysplasia
    • Hemberger M, Kurz H, Orth A, Otto S, Luttges A, Elliott R, et al. Genetic and developmental analysis of X-inactivation in interspecific hybrid mice suggests a role for the Y chromosome in placental dysplasia. Genetics. 2001;157(1):341-8.
    • (2001) Genetics , vol.157 , Issue.1 , pp. 341-348
    • Hemberger, M.1    Kurz, H.2    Orth, A.3    Otto, S.4    Luttges, A.5    Elliott, R.6
  • 18
    • 84867119793 scopus 로고    scopus 로고
    • Gonadotropin stimulation contributes to an increased incidence of epimutations in ICSI-derived mice
    • de Waal E, Yamazaki Y, Ingale P, Bartolomei MS, Yanagimachi R, McCarrey JR. Gonadotropin stimulation contributes to an increased incidence of epimutations in ICSI-derived mice. Hum Mol Genet. 2012;21(20):4460-72.
    • (2012) Hum Mol Genet , vol.21 , Issue.20 , pp. 4460-4472
    • Waal, E.1    Yamazaki, Y.2    Ingale, P.3    Bartolomei, M.S.4    Yanagimachi, R.5    McCarrey, J.R.6
  • 20
    • 84860351082 scopus 로고    scopus 로고
    • The transcriptional and epigenomic foundations of ground state pluripotency
    • Marks H, Kalkan T, Menafra R, Denissov S, Jones K, Hofemeister H, et al. The transcriptional and epigenomic foundations of ground state pluripotency. Cell. 2012;149(3):590-604.
    • (2012) Cell , vol.149 , Issue.3 , pp. 590-604
    • Marks, H.1    Kalkan, T.2    Menafra, R.3    Denissov, S.4    Jones, K.5    Hofemeister, H.6
  • 22
    • 84884133672 scopus 로고    scopus 로고
    • Whole-genome bisulfite sequencing of two distinct interconvertible DNA methylomes of mouse embryonic stem cells
    • Habibi E, Brinkman AB, Arand J, Kroeze LI, Kerstens HH, Matarese F, et al. Whole-genome bisulfite sequencing of two distinct interconvertible DNA methylomes of mouse embryonic stem cells. Cell Stem Cell. 2013;13(3):360-9.
    • (2013) Cell Stem Cell , vol.13 , Issue.3 , pp. 360-369
    • Habibi, E.1    Brinkman, A.B.2    Arand, J.3    Kroeze, L.I.4    Kerstens, H.H.5    Matarese, F.6
  • 23
    • 84928227321 scopus 로고    scopus 로고
    • Cell fate inclination within 2-cell and 4-cell mouse embryos revealed by single-cell RNA sequencing
    • Biase FH, Cao X, Zhong S. Cell fate inclination within 2-cell and 4-cell mouse embryos revealed by single-cell RNA sequencing. Genome Res. 2014;24(11):1787-96.
    • (2014) Genome Res , vol.24 , Issue.11 , pp. 1787-1796
    • Biase, F.H.1    Cao, X.2    Zhong, S.3
  • 24
    • 33746681910 scopus 로고    scopus 로고
    • Tissue-specific expression and regulation of sexually dimorphic genes in mice
    • Yang X, Schadt EE, Wang S, Wang H, Arnold AP, Ingram-Drake L, et al. Tissue-specific expression and regulation of sexually dimorphic genes in mice. Genome Res. 2006;16(8):995-1004.
    • (2006) Genome Res , vol.16 , Issue.8 , pp. 995-1004
    • Yang, X.1    Schadt, E.E.2    Wang, S.3    Wang, H.4    Arnold, A.P.5    Ingram-Drake, L.6
  • 25
    • 0942268864 scopus 로고    scopus 로고
    • Epigenetic dynamics of imprinted X inactivation during early mouse development
    • Okamoto I, Otte AP, Allis CD, Reinberg D, Heard E. Epigenetic dynamics of imprinted X inactivation during early mouse development. Science. 2004;303(5658):644-9.
    • (2004) Science , vol.303 , Issue.5658 , pp. 644-649
    • Okamoto, I.1    Otte, A.P.2    Allis, C.D.3    Reinberg, D.4    Heard, E.5
  • 26
    • 0347357614 scopus 로고    scopus 로고
    • Inheritance of a pre-inactivated paternal X chromosome in early mouse embryos
    • Huynh KD, Lee JT. Inheritance of a pre-inactivated paternal X chromosome in early mouse embryos. Nature. 2003;426(6968):857-62.
    • (2003) Nature , vol.426 , Issue.6968 , pp. 857-862
    • Huynh, K.D.1    Lee, J.T.2
  • 27
    • 65249115919 scopus 로고    scopus 로고
    • Dynamic changes in paternal X-chromosome activity during imprinted X-chromosome inactivation in mice
    • Patrat C, Okamoto I, Diabangouaya P, Vialon V, Le Baccon P, Chow J, et al. Dynamic changes in paternal X-chromosome activity during imprinted X-chromosome inactivation in mice. Proc Natl Acad Sci U S A. 2009;106(13):5198-203.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , Issue.13 , pp. 5198-5203
    • Patrat, C.1    Okamoto, I.2    Diabangouaya, P.3    Vialon, V.4    Baccon, P.5    Chow, J.6
  • 28
    • 84875936827 scopus 로고    scopus 로고
    • The genome-defence gene Tex19.1 suppresses LINE-1 retrotransposons in the placenta and prevents intra-uterine growth retardation in mice
    • Reichmann J, Reddington JP, Best D, Read D, Ollinger R, Meehan RR, et al. The genome-defence gene Tex19.1 suppresses LINE-1 retrotransposons in the placenta and prevents intra-uterine growth retardation in mice. Hum Mol Genet. 2013;22(9):1791-806.
    • (2013) Hum Mol Genet , vol.22 , Issue.9 , pp. 1791-1806
    • Reichmann, J.1    Reddington, J.P.2    Best, D.3    Read, D.4    Ollinger, R.5    Meehan, R.R.6
  • 29
    • 84878504294 scopus 로고    scopus 로고
    • Female bias in Rhox6 and 9 regulation by the histone demethylase KDM6A
    • Berletch JB, Deng X, Nguyen DK, Disteche CM. Female bias in Rhox6 and 9 regulation by the histone demethylase KDM6A. PLoS Genet. 2013;9(5):e1003489.
    • (2013) PLoS Genet , vol.9 , Issue.5
    • Berletch, J.B.1    Deng, X.2    Nguyen, D.K.3    Disteche, C.M.4
  • 30
    • 67650841094 scopus 로고    scopus 로고
    • Sex differences in the expression of hepatic drug metabolizing enzymes
    • Waxman DJ, Holloway MG. Sex differences in the expression of hepatic drug metabolizing enzymes. Mol Pharmacol. 2009;76(2):215-28.
    • (2009) Mol Pharmacol , vol.76 , Issue.2 , pp. 215-228
    • Waxman, D.J.1    Holloway, M.G.2
  • 31
    • 84868515935 scopus 로고    scopus 로고
    • Abundance of female-biased and paucity of male-biased somatically expressed genes on the mouse X-chromosome
    • Reinius B, Johansson MM, Radomska KJ, Morrow EH, Pandey GK, Kanduri C, et al. Abundance of female-biased and paucity of male-biased somatically expressed genes on the mouse X-chromosome. BMC Genomics. 2012;13:607.
    • (2012) BMC Genomics , vol.13 , pp. 607
    • Reinius, B.1    Johansson, M.M.2    Radomska, K.J.3    Morrow, E.H.4    Pandey, G.K.5    Kanduri, C.6
  • 32
    • 78649458548 scopus 로고    scopus 로고
    • RNA sequencing shows no dosage compensation of the active X-chromosome
    • Xiong Y, Chen X, Chen Z, Wang X, Shi S, Wang X, et al. RNA sequencing shows no dosage compensation of the active X-chromosome. Nat Genet. 2010;42(12):1043-7.
    • (2010) Nat Genet , vol.42 , Issue.12 , pp. 1043-1047
    • Xiong, Y.1    Chen, X.2    Chen, Z.3    Wang, X.4    Shi, S.5    Wang, X.6
  • 33
    • 67649644714 scopus 로고    scopus 로고
    • Elucidating the role of gonadal hormones in sexually dimorphic gene coexpression networks
    • van Nas A, Guhathakurta D, Wang SS, Yehya N, Horvath S, Zhang B, et al. Elucidating the role of gonadal hormones in sexually dimorphic gene coexpression networks. Endocrinology. 2009;150(3):1235-49.
    • (2009) Endocrinology , vol.150 , Issue.3 , pp. 1235-1249
    • Nas, A.1    Guhathakurta, D.2    Wang, S.S.3    Yehya, N.4    Horvath, S.5    Zhang, B.6
  • 34
    • 84863011066 scopus 로고    scopus 로고
    • Dynamic, sex-differential STAT5 and BCL6 binding to sex-biased, growth hormone-regulated genes in adult mouse liver
    • Zhang Y, Laz EV, Waxman DJ. Dynamic, sex-differential STAT5 and BCL6 binding to sex-biased, growth hormone-regulated genes in adult mouse liver. Mol Cell Biol. 2012;32(4):880-96.
    • (2012) Mol Cell Biol , vol.32 , Issue.4 , pp. 880-896
    • Zhang, Y.1    Laz, E.V.2    Waxman, D.J.3
  • 35
    • 77249095168 scopus 로고    scopus 로고
    • Intrinsic sex differences in the early growth hormone responsiveness of sex-specific genes in mouse liver
    • Wauthier V, Sugathan A, Meyer RD, Dombkowski AA, Waxman DJ. Intrinsic sex differences in the early growth hormone responsiveness of sex-specific genes in mouse liver. Mol Endocrinol. 2010;24(3):667-78.
    • (2010) Mol Endocrinol , vol.24 , Issue.3 , pp. 667-678
    • Wauthier, V.1    Sugathan, A.2    Meyer, R.D.3    Dombkowski, A.A.4    Waxman, D.J.5
  • 36
    • 77954370717 scopus 로고    scopus 로고
    • The X-linked imprinted gene family Fthl17 shows predominantly female expression following the two-cell stage in mouse embryos
    • Kobayashi S, Fujihara Y, Mise N, Kaseda K, Abe K, Ishino F, et al. The X-linked imprinted gene family Fthl17 shows predominantly female expression following the two-cell stage in mouse embryos. Nucleic Acids Res. 2010;38(11):3672-81.
    • (2010) Nucleic Acids Res , vol.38 , Issue.11 , pp. 3672-3681
    • Kobayashi, S.1    Fujihara, Y.2    Mise, N.3    Kaseda, K.4    Abe, K.5    Ishino, F.6
  • 37
    • 77956321991 scopus 로고    scopus 로고
    • Molecular basis of the first cell fate determination in mouse embryogenesis
    • Chen L, Wang D, Wu Z, Ma L, Daley GQ. Molecular basis of the first cell fate determination in mouse embryogenesis. Cell Res. 2010;20(9):982-93.
    • (2010) Cell Res , vol.20 , Issue.9 , pp. 982-993
    • Chen, L.1    Wang, D.2    Wu, Z.3    Ma, L.4    Daley, G.Q.5
  • 38
    • 17644408362 scopus 로고    scopus 로고
    • Sexual dimorphism in mammalian gene expression
    • Rinn JL, Snyder M. Sexual dimorphism in mammalian gene expression. Trends Genet. 2005;21(5):298-305.
    • (2005) Trends Genet , vol.21 , Issue.5 , pp. 298-305
    • Rinn, J.L.1    Snyder, M.2
  • 39
    • 84897575650 scopus 로고    scopus 로고
    • Maternal bias and escape from X chromosome imprinting in the midgestation mouse placenta
    • Finn EH, Smith CL, Rodriguez J, Sidow A, Baker JC. Maternal bias and escape from X chromosome imprinting in the midgestation mouse placenta. Dev Biol. 2014;390(1):80-92.
    • (2014) Dev Biol , vol.390 , Issue.1 , pp. 80-92
    • Finn, E.H.1    Smith, C.L.2    Rodriguez, J.3    Sidow, A.4    Baker, J.C.5
  • 40
    • 33646473832 scopus 로고    scopus 로고
    • Loss of Atrx affects trophoblast development and the pattern of X-inactivation in extraembryonic tissues
    • Garrick D, Sharpe JA, Arkell R, Dobbie L, Smith AJ, Wood WG, et al. Loss of Atrx affects trophoblast development and the pattern of X-inactivation in extraembryonic tissues. PLoS Genet. 2006;2(4):e58.
    • (2006) PLoS Genet , vol.2 , Issue.4
    • Garrick, D.1    Sharpe, J.A.2    Arkell, R.3    Dobbie, L.4    Smith, A.J.5    Wood, W.G.6
  • 41
    • 79955482843 scopus 로고    scopus 로고
    • Eutherian mammals use diverse strategies to initiate X-chromosome inactivation during development
    • Okamoto I, Patrat C, Thepot D, Peynot N, Fauque P, Daniel N, et al. Eutherian mammals use diverse strategies to initiate X-chromosome inactivation during development. Nature. 2011;472(7343):370-4.
    • (2011) Nature , vol.472 , Issue.7343 , pp. 370-374
    • Okamoto, I.1    Patrat, C.2    Thepot, D.3    Peynot, N.4    Fauque, P.5    Daniel, N.6
  • 42
    • 84883547823 scopus 로고    scopus 로고
    • Genome-wide analysis of chromatin states reveals distinct mechanisms of sex-dependent gene regulation in male and female mouse liver
    • Sugathan A, Waxman DJ. Genome-wide analysis of chromatin states reveals distinct mechanisms of sex-dependent gene regulation in male and female mouse liver. Mol Cell Biol. 2013;33(18):3594-610.
    • (2013) Mol Cell Biol , vol.33 , Issue.18 , pp. 3594-3610
    • Sugathan, A.1    Waxman, D.J.2
  • 43
    • 84866912634 scopus 로고    scopus 로고
    • UTX and UTY demonstrate histone demethylase-independent function in mouse embryonic development
    • Shpargel KB, Sengoku T, Yokoyama S, Magnuson T. UTX and UTY demonstrate histone demethylase-independent function in mouse embryonic development. PLoS Genet. 2012;8(9):e1002964.
    • (2012) PLoS Genet , vol.8 , Issue.9
    • Shpargel, K.B.1    Sengoku, T.2    Yokoyama, S.3    Magnuson, T.4
  • 45
    • 77956595381 scopus 로고    scopus 로고
    • Sexual dimorphism in mammalian autosomal gene regulation is determined not only by Sry but by sex chromosome complement as well
    • Wijchers PJ, Yandim C, Panousopoulou E, Ahmad M, Harker N, Saveliev A, et al. Sexual dimorphism in mammalian autosomal gene regulation is determined not only by Sry but by sex chromosome complement as well. Dev Cell. 2010;19(3):477-84.
    • (2010) Dev Cell , vol.19 , Issue.3 , pp. 477-484
    • Wijchers, P.J.1    Yandim, C.2    Panousopoulou, E.3    Ahmad, M.4    Harker, N.5    Saveliev, A.6
  • 46
    • 84868693848 scopus 로고    scopus 로고
    • Sex-specific mouse liver gene expression: genome-wide analysis of developmental changes from pre-pubertal period to young adulthood
    • Conforto TL, Waxman DJ. Sex-specific mouse liver gene expression: genome-wide analysis of developmental changes from pre-pubertal period to young adulthood. Biol Sex Differ. 2012;3:9.
    • (2012) Biol Sex Differ , vol.3 , pp. 9
    • Conforto, T.L.1    Waxman, D.J.2
  • 47
    • 77958596171 scopus 로고    scopus 로고
    • Chronic high-fat diet in fathers programs beta-cell dysfunction in female rat offspring
    • Ng SF, Lin RC, Laybutt DR, Barres R, Owens JA, Morris MJ. Chronic high-fat diet in fathers programs beta-cell dysfunction in female rat offspring. Nature. 2010;467(7318):963-6.
    • (2010) Nature , vol.467 , Issue.7318 , pp. 963-966
    • Ng, S.F.1    Lin, R.C.2    Laybutt, D.R.3    Barres, R.4    Owens, J.A.5    Morris, M.J.6
  • 49
    • 84887321105 scopus 로고    scopus 로고
    • Epigenetic effects on the embryo as a result of periconceptional environment and assisted reproduction technology
    • Lucas E. Epigenetic effects on the embryo as a result of periconceptional environment and assisted reproduction technology. Reprod Biomed Online. 2013;27(5):477-85.
    • (2013) Reprod Biomed Online , vol.27 , Issue.5 , pp. 477-485
    • Lucas, E.1
  • 50
    • 77749323185 scopus 로고    scopus 로고
    • RNA-Seq analysis to capture the transcriptome landscape of a single cell
    • Tang F, Barbacioru C, Nordman E, Li B, Xu N, Bashkirov VI, et al. RNA-Seq analysis to capture the transcriptome landscape of a single cell. Nat Protoc. 2010;5(3):516-35.
    • (2010) Nat Protoc , vol.5 , Issue.3 , pp. 516-535
    • Tang, F.1    Barbacioru, C.2    Nordman, E.3    Li, B.4    Xu, N.5    Bashkirov, V.I.6
  • 51
    • 70349934958 scopus 로고    scopus 로고
    • Suppression of Erk signalling promotes ground state pluripotency in the mouse embryo
    • Nichols J, Silva J, Roode M, Smith A. Suppression of Erk signalling promotes ground state pluripotency in the mouse embryo. Development. 2009;136(19):3215-22.
    • (2009) Development , vol.136 , Issue.19 , pp. 3215-3222
    • Nichols, J.1    Silva, J.2    Roode, M.3    Smith, A.4
  • 52
    • 60149095014 scopus 로고    scopus 로고
    • Global analysis of the insulator binding protein CTCF in chromatin barrier regions reveals demarcation of active and repressive domains
    • Cuddapah S, Jothi R, Schones DE, Roh TY, Cui K, Zhao K. Global analysis of the insulator binding protein CTCF in chromatin barrier regions reveals demarcation of active and repressive domains. Genome Res. 2009;19(1):24-32.
    • (2009) Genome Res , vol.19 , Issue.1 , pp. 24-32
    • Cuddapah, S.1    Jothi, R.2    Schones, D.E.3    Roh, T.Y.4    Cui, K.5    Zhao, K.6


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