메뉴 건너뛰기




Volumn 48, Issue 3, 2015, Pages 139-146

Local protein synthesis in neuronal axons: Why and how we study

Author keywords

Axon; Axon TRAP; BONCAT; Boyden chamber; Campenot chamber; Compartmentalized culture; Laser capture microdissection; Local mRNA translation; Microfluidic device; Neuron; Protein synthesis; Puromycin tagging; Ribosome; SILAC

Indexed keywords

NERVE PROTEIN;

EID: 84928239596     PISSN: 19766696     EISSN: 1976670X     Source Type: Journal    
DOI: 10.5483/BMBRep.2015.48.3.010     Document Type: Review
Times cited : (33)

References (40)
  • 2
    • 0020063563 scopus 로고
    • Preferential localization of polyribosomes under the base of dendritic spines in granule cells of the dentate gyrus
    • Steward O and Levy WB (1982) Preferential localization of polyribosomes under the base of dendritic spines in granule cells of the dentate gyrus. J Neurosci 2, 284-291
    • (1982) J Neurosci , vol.2 , pp. 284-291
    • Steward, O.1    Levy, W.B.2
  • 3
    • 33749077101 scopus 로고    scopus 로고
    • Dendritic protein synthesis, synaptic plasticity, and memory
    • Sutton MA and Schuman EM (2006) Dendritic protein synthesis, synaptic plasticity, and memory. Cell 127, 49-58
    • (2006) Cell , vol.127 , pp. 49-58
    • Sutton, M.A.1    Schuman, E.M.2
  • 4
    • 0022475064 scopus 로고
    • Polyribosomes associated with synaptic specializations on axon initial segments: localization of protein-synthetic machinery at inhibitory synapses
    • Steward O and Ribak CE (1986) Polyribosomes associated with synaptic specializations on axon initial segments: localization of protein-synthetic machinery at inhibitory synapses. J Neurosci 6, 3079-3085
    • (1986) J Neurosci , vol.6 , pp. 3079-3085
    • Steward, O.1    Ribak, C.E.2
  • 5
    • 0015078708 scopus 로고
    • Ultrastructure and function of growth cones and axons of cultured nerve cells
    • Yamada KM, Spooner BS and Wessells NK (1971) Ultrastructure and function of growth cones and axons of cultured nerve cells. J Cell Biol 49, 614-635
    • (1971) J Cell Biol , vol.49 , pp. 614-635
    • Yamada, K.M.1    Spooner, B.S.2    Wessells, N.K.3
  • 6
    • 0014700366 scopus 로고
    • The fine structure of the axon and growth cone of the dorsal root neuroblast of the rabbit embryo
    • Tennyson VM (1970) The fine structure of the axon and growth cone of the dorsal root neuroblast of the rabbit embryo. J Cell Biol 44, 62-79
    • (1970) J Cell Biol , vol.44 , pp. 62-79
    • Tennyson, V.M.1
  • 7
    • 0014896328 scopus 로고
    • Ribosome-like particles in myelinated axons of the rat
    • Zelena J (1970) Ribosome-like particles in myelinated axons of the rat. Brain Res 24, 359-363
    • (1970) Brain Res , vol.24 , pp. 359-363
    • Zelena, J.1
  • 8
    • 0035924590 scopus 로고    scopus 로고
    • Chemotropic responses of retinal growth cones mediated by rapid local protein synthesis and degradation
    • Campbell DS and Holt CE (2001) Chemotropic responses of retinal growth cones mediated by rapid local protein synthesis and degradation. Neuron 32, 1013-1026
    • (2001) Neuron , vol.32 , pp. 1013-1026
    • Campbell, D.S.1    Holt, C.E.2
  • 9
    • 0037079094 scopus 로고    scopus 로고
    • Localized synaptic potentiation by BDNF requires local protein synthesis in the developing axon
    • Zhang X and Poo MM (2002) Localized synaptic potentiation by BDNF requires local protein synthesis in the developing axon. Neuron 36, 675-688
    • (2002) Neuron , vol.36 , pp. 675-688
    • Zhang, X.1    Poo, M.M.2
  • 10
    • 84859954603 scopus 로고    scopus 로고
    • Axonal mRNA localization and local protein synthesis in nervous system assembly, maintenance and repair
    • Jung H, Yoon BC and Holt CE (2012) Axonal mRNA localization and local protein synthesis in nervous system assembly, maintenance and repair. Nat Rev Neurosci 13, 308-324
    • (2012) Nat Rev Neurosci , vol.13 , pp. 308-324
    • Jung, H.1    Yoon, B.C.2    Holt, C.E.3
  • 11
    • 84893776968 scopus 로고    scopus 로고
    • Subcellular transcriptomics-dissection of the mRNA composition in the axonal compartment of sensory neurons
    • Minis A, Dahary D, Manor O, Leshkowitz D, Pilpel Y and Yaron A (2014) Subcellular transcriptomics-dissection of the mRNA composition in the axonal compartment of sensory neurons. Dev Neurobiol 74, 365-381
    • (2014) Dev Neurobiol , vol.74 , pp. 365-381
    • Minis, A.1    Dahary, D.2    Manor, O.3    Leshkowitz, D.4    Pilpel, Y.5    Yaron, A.6
  • 12
    • 77649097483 scopus 로고    scopus 로고
    • An NGF-responsive element targets myo-inositol monophosphatase-1 mRNA to sympathetic neuron axons
    • Andreassi C, Zimmermann C, Mitter R et al (2010) An NGF-responsive element targets myo-inositol monophosphatase-1 mRNA to sympathetic neuron axons. Nat Neurosci 13, 291-301
    • (2010) Nat Neurosci , vol.13 , pp. 291-301
    • Andreassi, C.1    Zimmermann, C.2    Mitter, R.3
  • 13
    • 78650474986 scopus 로고    scopus 로고
    • Transcriptome analysis of embryonic and adult sensory axons reveals changes in mRNA repertoire localization
    • Gumy LF, Yeo GS, Tung YC et al (2011) Transcriptome analysis of embryonic and adult sensory axons reveals changes in mRNA repertoire localization. RNA 17, 85-98
    • (2011) RNA , vol.17 , pp. 85-98
    • Gumy, L.F.1    Yeo, G.S.2    Tung, Y.C.3
  • 15
    • 78449243094 scopus 로고    scopus 로고
    • Subcellular profiling reveals distinct and developmentally regulated repertoire of growth cone mRNAs
    • Zivraj KH, Tung YC, Piper M et al (2010) Subcellular profiling reveals distinct and developmentally regulated repertoire of growth cone mRNAs. J Neurosci 30, 15464-15478
    • (2010) J Neurosci , vol.30 , pp. 15464-15478
    • Zivraj, K.H.1    Tung, Y.C.2    Piper, M.3
  • 16
    • 19944432196 scopus 로고    scopus 로고
    • Differential transport and local translation of cytoskeletal, injury-response, and neurodegeneration protein mRNAs in axons
    • Willis D, Li KW, Zheng JQ et al (2005) Differential transport and local translation of cytoskeletal, injury-response, and neurodegeneration protein mRNAs in axons. J Neurosci 25, 778-791
    • (2005) J Neurosci , vol.25 , pp. 778-791
    • Willis, D.1    Li, K.W.2    Zheng, J.Q.3
  • 17
  • 18
    • 1842313862 scopus 로고
    • Local control of neurite development by nerve growth factor
    • Campenot RB (1977) Local control of neurite development by nerve growth factor. Proc Natl Acad Sci U S A 74, 4516-4519
    • (1977) Proc Natl Acad Sci U S A , vol.74 , pp. 4516-4519
    • Campenot, R.B.1
  • 19
    • 80055119852 scopus 로고    scopus 로고
    • Preparation and maintenance of dorsal root ganglia neurons in compartmented cultures
    • Pazyra-Murphy MF and Segal RA (2008) Preparation and maintenance of dorsal root ganglia neurons in compartmented cultures. J Vis Exp 20, 951
    • (2008) J Vis Exp , vol.20 , pp. 951
    • Pazyra-Murphy, M.F.1    Segal, R.A.2
  • 20
    • 0343841187 scopus 로고
    • The chemotactic effect of mixtures of antibody and antigen on polymorphonuclear leucocytes
    • Boyden S (1962) The chemotactic effect of mixtures of antibody and antigen on polymorphonuclear leucocytes. J Exp Med 115, 453-466
    • (1962) J Exp Med , vol.115 , pp. 453-466
    • Boyden, S.1
  • 21
    • 79960034967 scopus 로고    scopus 로고
    • Profiling axonal mRNA transport
    • Willis DE and Twiss JL (2011) Profiling axonal mRNA transport. Methods Mol Biol 714, 335-352
    • (2011) Methods Mol Biol , vol.714 , pp. 335-352
    • Willis, D.E.1    Twiss, J.L.2
  • 24
    • 33745464039 scopus 로고    scopus 로고
    • Selective identification of newly synthesized proteins in mammalian cells using bioorthogonal noncanonical amino acid tagging (BONCAT)
    • Dieterich DC, Link AJ, Graumann J, Tirrell DA and Schuman EM (2006) Selective identification of newly synthesized proteins in mammalian cells using bioorthogonal noncanonical amino acid tagging (BONCAT). Proc Natl Acad Sci U S A 103, 9482-9487
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 9482-9487
    • Dieterich, D.C.1    Link, A.J.2    Graumann, J.3    Tirrell, D.A.4    Schuman, E.M.5
  • 25
    • 0036583926 scopus 로고    scopus 로고
    • Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomics
    • Ong SE, Blagoev B, Kratchmarova I et al (2002) Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomics. Mol Cell Proteomics 1, 376-386
    • (2002) Mol Cell Proteomics , vol.1 , pp. 376-386
    • Ong, S.E.1    Blagoev, B.2    Kratchmarova, I.3
  • 27
    • 84897133420 scopus 로고    scopus 로고
    • Genomewide identification and quantification of protein synthesis in cultured cells and whole tissues by puromycin-associated nascent chain proteomics (PUNCH-P)
    • Aviner R, Geiger T and Elroy-Stein O (2014) Genomewide identification and quantification of protein synthesis in cultured cells and whole tissues by puromycin-associated nascent chain proteomics (PUNCH-P). Nat Protoc 9, 751-760
    • (2014) Nat Protoc , vol.9 , pp. 751-760
    • Aviner, R.1    Geiger, T.2    Elroy-Stein, O.3
  • 28
    • 55449107738 scopus 로고    scopus 로고
    • A translational profiling approach for the molecular characterization of CNS cell types
    • Heiman M, Schaefer A, Gong S et al (2008) A translational profiling approach for the molecular characterization of CNS cell types. Cell 135, 738-748
    • (2008) Cell , vol.135 , pp. 738-748
    • Heiman, M.1    Schaefer, A.2    Gong, S.3
  • 29
    • 79960779323 scopus 로고    scopus 로고
    • FMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autism
    • Darnell JC, Van Driesche SJ, Zhang C et al (2011) FMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autism. Cell 146, 247-261
    • (2011) Cell , vol.146 , pp. 247-261
    • Darnell, J.C.1    Van Driesche, S.J.2    Zhang, C.3
  • 30
    • 62549134121 scopus 로고    scopus 로고
    • Genome-wide analysis in vivo of translation with nucleotide resolution using ribosome profiling
    • Ingolia NT, Ghaemmaghami S, Newman JR and Weissman JS (2009) Genome-wide analysis in vivo of translation with nucleotide resolution using ribosome profiling. Science 324, 218-223
    • (2009) Science , vol.324 , pp. 218-223
    • Ingolia, N.T.1    Ghaemmaghami, S.2    Newman, J.R.3    Weissman, J.S.4
  • 31
    • 0034990497 scopus 로고    scopus 로고
    • Dynamic visualization of local protein synthesis in hippocampal neurons
    • Aakalu G, Smith WB, Nguyen N, Jiang C and Schuman EM (2001) Dynamic visualization of local protein synthesis in hippocampal neurons. Neuron 30, 489-502
    • (2001) Neuron , vol.30 , pp. 489-502
    • Aakalu, G.1    Smith, W.B.2    Nguyen, N.3    Jiang, C.4    Schuman, E.M.5
  • 32
    • 50349086011 scopus 로고    scopus 로고
    • Live visualization of protein synthesis in axonal growth cones by microinjection of photoconvertible Kaede into Xenopus embryos
    • Leung KM and Holt CE (2008) Live visualization of protein synthesis in axonal growth cones by microinjection of photoconvertible Kaede into Xenopus embryos. Nat Protoc 3, 1318-1327
    • (2008) Nat Protoc , vol.3 , pp. 1318-1327
    • Leung, K.M.1    Holt, C.E.2
  • 33
    • 79958041082 scopus 로고    scopus 로고
    • Local translation of mRNAs in neural development
    • Jung H and Holt CE (2011) Local translation of mRNAs in neural development. Wiley Interdiscip Rev RNA 2, 153-165
    • (2011) Wiley Interdiscip Rev RNA , vol.2 , pp. 153-165
    • Jung, H.1    Holt, C.E.2
  • 34
    • 0035930608 scopus 로고    scopus 로고
    • Reversible glutathionylation regulates actin polymerization in A431 cells
    • Wang J, Boja ES, Tan W et al (2001) Reversible glutathionylation regulates actin polymerization in A431 cells. J Biol Chem 276, 47763-47766
    • (2001) J Biol Chem , vol.276 , pp. 47763-47766
    • Wang, J.1    Boja, E.S.2    Tan, W.3
  • 35
    • 33745993606 scopus 로고    scopus 로고
    • Arginylation of beta-actin regulates actin cytoskeleton and cell motility
    • Karakozova M, Kozak M, Wong CC et al (2006) Arginylation of beta-actin regulates actin cytoskeleton and cell motility. Science 313, 192-196
    • (2006) Science , vol.313 , pp. 192-196
    • Karakozova, M.1    Kozak, M.2    Wong, C.C.3
  • 36
    • 84900339887 scopus 로고    scopus 로고
    • Proteome labeling and protein identification in specific tissues and at specific developmental stages in an animal
    • Elliott TS, Townsley FM, Bianco A et al (2014) Proteome labeling and protein identification in specific tissues and at specific developmental stages in an animal. Nat Biotechnol 32, 465-472
    • (2014) Nat Biotechnol , vol.32 , pp. 465-472
    • Elliott, T.S.1    Townsley, F.M.2    Bianco, A.3
  • 37
    • 78650947724 scopus 로고    scopus 로고
    • Presynaptic protein synthesis required for NT-3-induced long-term synaptic modulation
    • Je HS, Ji Y, Wang Y, Yang F, Wu W and Lu B (2011) Presynaptic protein synthesis required for NT-3-induced long-term synaptic modulation. Mol Brain 4, 1
    • (2011) Mol Brain , vol.4 , pp. 1
    • Je, H.S.1    Ji, Y.2    Wang, Y.3    Yang, F.4    Wu, W.5    Lu, B.6
  • 38
    • 66149168579 scopus 로고    scopus 로고
    • Chemically inducible inactivation of protein synthesis in genetically targeted neurons
    • Je HS, Lu Y, Yang F et al (2009) Chemically inducible inactivation of protein synthesis in genetically targeted neurons. J Neurosci 29, 6761-6766
    • (2009) J Neurosci , vol.29 , pp. 6761-6766
    • Je, H.S.1    Lu, Y.2    Yang, F.3
  • 39
    • 34547863548 scopus 로고    scopus 로고
    • Taking control of gene expression with light-activated oligonucleotid
    • 163+165 passim
    • Dmochowski IJ and Tang X (2007) Taking control of gene expression with light-activated oligonucleotid. Biotechniques 43, 161, 163, 165 passim
    • (2007) Biotechniques , vol.43 , pp. 161
    • Dmochowski, I.J.1    Tang, X.2
  • 40
    • 84864296464 scopus 로고    scopus 로고
    • Subcellular knockout of importin beta1 perturbs axonal retrograde signaling
    • Perry RB, Doron-Mandel E, Iavnilovitch E et al (2012) Subcellular knockout of importin beta1 perturbs axonal retrograde signaling. Neuron 75, 294-305
    • Neuron , vol.75 , pp. 294-305
    • Perry, R.B.1    Doron-Mandel, E.2    Iavnilovitch, E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.