Principles of rehabilitation and reactivation: Pulmonary hypertension

Respiration

Volumn 89, Issue 4, 2015, Pages 265-273

  Marra, Alberto M ^a,b   Egenlauf, Benjamin ^a   Bossone, Eduardo ^c,d   Eichstaedt, Christina ^a   Grünig, Ekkehard ^a   Ehlken, Nicola ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^c UNIVERSITY OF SALERNO   (Italy)

^d IRCCS POLICLINICO SAN DONATO   (Italy)

Author keywords

Exercise training; Pulmonary arterial hypertension; Pulmonary hypertension; Rehabilitation; Right heart failure

Indexed keywords

ARTICLE; CYCLING; DISEASE EXACERBATION; DISEASE SEVERITY; EXERCISE; FUNCTIONAL STATUS; HEART RIGHT VENTRICLE FAILURE; HUMAN; LUNG HEMODYNAMICS; NONHUMAN; PATIENT CARE; PATIENT SAFETY; PRIORITY JOURNAL; PULMONARY HYPERTENSION; PULMONARY REHABILITATION; QUALITY OF LIFE; RANDOMIZED CONTROLLED TRIAL (TOPIC); RESISTANCE TRAINING; SELF CARE; SURVIVAL RATE; TREADMILL EXERCISE; ANIMAL; ANIMAL EXPERIMENT; HYPERTENSION, PULMONARY; PHYSIOLOGY;

ANIMALS; HUMANS; HYPERTENSION, PULMONARY; PHYSICAL CONDITIONING, ANIMAL; PHYSICAL CONDITIONING, HUMAN;

EID: 84928212916     PISSN: 00257931     EISSN: 14230356     Source Type: Journal    
DOI: 10.1159/000371855     Document Type: Article

References (39)

1. Galie N, Hoeper MM, Humbert M, et al. Guidelines for the diagnosis and treatment of pulmonary hypertension: the Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS), endorsed by the International Society of Heart and Lung Transplantation (ISHLT). Eur Heart J. 2009; 30: 2493-2537
2. Grunig E, Barner A, Bell M, et al. Non-invasive diagnosis of pulmonary hypertension: ESC/ERS Guidelines with Updated Commentary of the Cologne Consensus Conference 2011. Int J Cardiol. 2011; 154(suppl 1): S3-S12
3. Galie N, Corris PA, Frost A, et al. Updated treatment algorithm of pulmonary arterial hypertension. J Am Coll Cardiol. 2013; 62: D60-D72
4. Ghofrani HA, D'Armini AM, Grimminger F, et al. Riociguat for the treatment of chronic thromboembolic pulmonary hypertension. N Engl J Med. 2013; 369: 319-329
5. Gomberg-Maitland M, Bull TM, Saggar R, et al. New trial designs and potential therapies for pulmonary artery hypertension. J Am Coll Cardiol. 2013; 62: D82-D91
6. Rubin LJ. Exercise training for pulmonary hypertension: another prescription to write? Eur Respir J. 2012; 40: 7-8
7. Grunig E, Lichtblau M, Ehlken N, et al. Safety and efficacy of exercise training in various forms of pulmonary hypertension. Eur Respir J. 2012; 40: 84-92
8. Mereles D, Ehlken N, Kreuscher S, et al. Exercise and respiratory training improve exercise capacity and quality of life in patients with severe chronic pulmonary hypertension. Circulation. 2006; 114: 1482-1489
9. de Man FS, Handoko ML, Groepenhoff H, et al. Effects of exercise training in patients with idiopathic pulmonary arterial hypertension. Eur Respir J. 2009; 34: 669-675
10. Grunig E, Ehlken N, Ghofrani A, et al. Effect of exercise and respiratory training on clinical progression and survival in patients with severe chronic pulmonary hypertension. Respiration. 2011; 81: 394-401
11. Grunig E, Maier F, Ehlken N, et al. Exercise training in pulmonary arterial hypertension associated with connective tissue diseases. Arthritis Res Ther. 2012; 14: R148
12. Becker-Grunig T, Klose H, Ehlken N, et al. Efficacy of exercise training in pulmonary arterial hypertension associated with congenital heart disease. Int J Cardiol. 2013; 168: 375-381
13. Weinstein AA, Chin LM, Keyser RE, et al. Effect of aerobic exercise training on fatigue and physical activity in patients with pulmonary arterial hypertension. Respir Med. 2013; 107: 778-784
14. Chan L, Chin LM, Kennedy M, et al. Benefits of intensive treadmill exercise training on cardiorespiratory function and quality of life in patients with pulmonary hypertension. Chest. 2013; 143: 333-343
15. Weissmann N, Peters DM, Klopping C, et al. Structural and functional prevention of hypoxia-induced pulmonary hypertension by individualized exercise training in mice. Am J Physiol Lung Cell Mol Physiol. 2014; 306: L986-L995
16. Colombo R, Siqueira R, Becker CU, et al. Effects of exercise on monocrotaline-induced changes in right heart function and pulmonary artery remodeling in rats. Can J Physiol Pharmacol. 2013; 91: 38-44
17. Favret F, Henderson KK, Allen J, Richalet JP, Gonzalez NC. Exercise training improves lung gas exchange and attenuates acute hypoxic pulmonary hypertension but does not prevent pulmonary hypertension of prolonged hypoxia. J Appl Physiol. 2006; 100: 20-25
18. Goret L, Reboul C, Tanguy S, Dauzat M, Obert P. Training does not affect the alteration in pulmonary artery vasoreactivity in pulmonary hypertensive rats. Eur J Pharmacol. 2005; 527: 121-128
19. Hassoun PM, Mouthon L, Barbera JA, et al. Inflammation, growth factors, and pulmonary vascular remodeling. J Am Coll Cardiol. 2009; 54: S10-S19
20. Soon E, Holmes AM, Treacy CM, et al. Elevated levels of inflammatory cytokines predict survival in idiopathic and familial pulmonary arterial hypertension. Circulation. 2010; 122: 920-927
21. Lavie CJ, Church TS, Milani RV, Earnest CP. Impact of physical activity, cardiorespiratory fitness, and exercise training on markers of inflammation. J Cardiopulm Rehabil Prev. 2011; 31: 137-145
22. Mann DL, Reid MB. Exercise training and skeletal muscle inflammation in chronic heart failure: feeling better about fatigue. J Am Coll Cardiol. 2003; 42: 869-872
23. Bauer R, Dehnert C, Schoene P, et al. Skeletal muscle dysfunction in patients with idiopathic pulmonary arterial hypertension. Respir Med. 2007; 101: 2366-2369
24. Mainguy V, Maltais F, Saey D, et al. Peripheral muscle dysfunction in idiopathic pulmonary arterial hypertension. Thorax. 2010; 65: 113-117
25. Batt J, Ahmed SS, Correa J, Bain A, Granton J. Skeletal muscle dysfunction in idiopathic pulmonary arterial hypertension. Am J Respir Cell Mol Biol. 2014; 50: 74-86
26. Mainguy V, Maltais F, Saey D, et al. Effects of a rehabilitation program on skeletal muscle function in idiopathic pulmonary arterial hypertension. J Cardiopulm Rehabil Prev. 2010; 30: 319-323
27. Favret F, Henderson KK, Richalet JP, Gonzalez NC. Effects of exercise training on acclimatization to hypoxia: systemic O 2 transport during maximal exercise. J Appl Physiol (1985) 2003; 95: 1531-1541
28. Handoko ML, de Man FS, Happe CM, et al. Opposite effects of training in rats with stable and progressive pulmonary hypertension. Circulation. 2009; 120: 42-49
29. Karvonen MJ, Kentala E, Mustala O. The effects of training on heart rate; a longitudinal study. Ann Med Exp Biol Fenn. 1957; 35: 307-315
30. Raskin J, Qua D, Marks T, Sulica R A retrospective study on the effects of pulmonary rehabilitation in patients with pulmonary hypertension. Chron Respir Dis. 2014; 11: 153-162
31. Ley S, Fink C, Risse F, et al. Magnetic resonance imaging to assess the effect of exercise training on pulmonary perfusion and blood flow in patients with pulmonary hypertension. Eur Radiol. 2013; 23: 324-331
32. Kabitz HJ, Bremer HC, Schwoerer A, et al. The combination of exercise and respiratory training improves respiratory muscle function in pulmonary hypertension. Lung. 2014; 192: 321-328
33. Ehlken N, Verduyn C, Tiede H, et al. Economic evaluation of exercise training in patients with pulmonary hypertension. Lung. 2014; 192: 359-366
34. Nagel C, Prange F, Guth S, et al. Exercise training improves exercise capacity and quality of life in patients with inoperable or residual chronic thromboembolic pulmonary hypertension. PLoS One. 2012; 7: e41603
35. Martinez-Quintana E, Miranda-Calderin G, Ugarte-Lopetegui A, Rodriguez-Gonzalez F. Rehabilitation program in adult congenital heart disease patients with pulmonary hypertension. Congenit Heart Dis. 2010; 5: 44-50
36. Yuan P XX, Sun XY, Pudasaini B, Liu JM, Hu QH. Exercise training for pulmonary hypertension: a systematic review and meta-Analysis. Int J Cardiol. 2015; 178: 142-146
37. Rich S, Dantzker DR, Ayres SM, et al. Primary pulmonary hypertension A national prospective study. Ann Intern Med. 1987; 107: 216-223
38. Fox BD, Kassirer M, Weiss I, et al. Ambulatory rehabilitation improves exercise capacity in patients with pulmonary hypertension. J Card Fail. 2011; 17: 196-200
39. Shoemaker MJ, Wilt JL, Dasgupta R, Oudiz RJ. Exercise training in patients with pulmonary arterial hypertension: a case report. Cardiopulm Phys Ther Journal. 2009; 20: 12-18