Comparative tissue proteomics analysis of thoracic aortic dissection with hypertension using the iTRAQ technique

European Journal of Cardio-thoracic Surgery

Volumn 47, Issue 3, 2015, Pages 431-438

  Zhang, Kefeng ^a   Pan, Xudong ^b   Zheng, Jun ^b   Xu, Dong ^a   Zhang, Jian ^a   Sun, Lizhong ^b  

^a CAPITAL MEDICAL UNIVERSITY   (China)

^b CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

ITRAQ; Proteomics; Thoracic aortic dissection

Indexed keywords

ALPHA 1 ANTITRYPSIN; ALTERNATIVE COMPLEMENT PATHWAY C3 C5 CONVERTASE; APOLIPOPROTEIN A1; APOLIPOPROTEIN B100; COLLAGEN TYPE 1; COLLAGEN TYPE 4; DECORIN; DJ 1 PROTEIN; ERYTHROCYTE BAND 3 PROTEIN; FIBRILLIN 1; FIBRINOGEN; HEMOGLOBIN BETA CHAIN; HISTONE H4; INTERLEUKIN 6; KERATIN TYPE II; LACTADHERIN; LAMININ GAMMA1; LIPOCORTIN 2; PROTEIN; PROTEOHEPARAN SULFATE; SEROTRANSFERRIN; SERUM ALBUMIN; SERUM AMYLOID P; SPECTRIN; SPECTRIN BETA 1; TENASCIN; TRANSFERRIN; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; UNINDEXED DRUG; VERSICAN; PROTEOME;

ADULT; AORTA DISSECTION; AORTA WALL; ARTICLE; CELL ADHESION; CONTROLLED STUDY; DATA ANALYSIS SOFTWARE; DOWN REGULATION; EXTRACELLULAR MATRIX; FEMALE; HUMAN; HUMAN TISSUE; HYPERTENSION; INFLAMMATION; ITRAQ TECHNIQUE; LIMIT OF QUANTITATION; MALE; MOLECULAR PATHOLOGY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DENATURATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEOMICS; QUANTITATIVE ANALYSIS; SIGNAL TRANSDUCTION; THORACIC AORTIC DISSECTION; UPREGULATION; WESTERN BLOTTING; CHEMISTRY; DISSECTING ANEURYSM; ISOTOPE LABELING; METABOLISM; PROCEDURES; PROTEIN PROTEIN INTERACTION; THORACIC AORTA; THORACIC AORTA ANEURYSM;

ANEURYSM, DISSECTING; AORTA, THORACIC; AORTIC ANEURYSM, THORACIC; HUMANS; ISOTOPE LABELING; PROTEIN INTERACTION MAPS; PROTEOME; PROTEOMICS; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA;

EID: 84928199525     PISSN: 10107940     EISSN: 1873734X     Source Type: Journal    
DOI: 10.1093/ejcts/ezu171     Document Type: Article

References (21)

1. Jones JA, Spinale FG, Ikonomidis JS. Transforming growth factor-beta signaling in thoracic aortic aneurysm development: a paradox in pathogenesis. J Vasc Res 2009;46:119-37.
2. Xiong W, Meisinger T, Knispel R, Worth JM, Baxter BT. MMP-2 regulates Erk1/2 phosphorylation and aortic dilatation in Marfan syndrome. Circ Res 2012;110:e92-e101.
3. Pilop C, Aregger F, Gorman RC, Brunisholz R, Gerrits B, Schaffner T et al. Proteomic analysis in aortic media of patients with Marfan syndrome reveals increased activity of calpain 2 in aortic aneurysms. Circulation 2009;120:983-91.
4. Liao M, Liu Z, Bao J, Zhao Z, Hu J, Feng X et al. A proteomic study of the aortic media in human thoracic aortic dissection: implication for oxidative stress. J Thorac Cardiovasc Surg 2008;136:65-72.
5. Glen A, Gan CS, Hamdy FC, Eaton CL, Cross SS, Catto JW et al. iTRAQ-facilitated proteomic analysis of human prostate cancer cells identifies proteins associated with progression. J Proteome Res 2008;7:897-907.
6. El-Hamamsy I, Yacoub MH. Cellular and molecular mechanisms of thoracic aortic aneurysms. Nat Rev Cardiol 2009;6:771-86.
7. Golledge J, Eagle KA. Acute aortic dissection. Lancet 2008;372:55-66.
8. Wang X, LeMaire SA, Chen L, Carter SA, Shen YH, Gan Y et al. Decreased expression of fibulin-5 correlates with reduced elastin in thoracic aortic dissection. Surgery 2005;138:352-59.
9. Judge DP, Dietz HC. Marfan's syndrome. Lancet 2005;366:1965-76.
10. Albornoz G, Coady MA, Roberts M, Davies RR, Tranquilli M, Rizzo JA et al. Familial thoracic aortic aneurysms and dissections: incidence, modes of inheritance, and phenotypic patterns. Ann Thorac Surg 2006;82:1400-05.
11. Hasham SN, Willing MC, Guo DC, Muilenburg A, He R, Tran VT et al. Mapping a locus for familiar thoracic aortic aneurysms and dissections (TAAD2) to 3p24-25. Circulation 2003;107:3184-90.
12. Mirza SP. Quantitative mass spectrometry-based approaches in cardiovascular research. Circ Cardiovasc Genet 2012;5:477-84.
13. Gu G, Cheng W, Yao C, Yin J, Tong C, Rao A et al. Quantitative proteomics analysis by isobaric tags for relative and absolute quantitation identified Lumican as a potential marker for acute aortic dissection. J Biomed Biotechnol 2011;2011:920763.
14. Zhang X, Guo Y, Song Y, Sun W, Yu C, Zhao X et al. Proteomic analysis of individual variation in normal livers of human beings using difference gel electrophoresis. Proteomics 2006;6:5260-8.
15. Chaudhry SS, Cain SA, Morgan A, Dallas SL, Shuttleworth CA, Kielty CM. Fibrillin-1 regulates the bioavailability of TGFβ1. J Cell Biol 2007;176:355-67.
16. Isogai Z, Ono RN, Ushiro S, Keene DR, Chen Y, Mazzieri R et al. Latent transforming growth factor β-binding protein 1 interacts with fibrillin and is a microfibril-associated protein. J Biol Chem 2003;278:2750-7.
17. Zacchigna L, Vecchione C, Notte A, Cordenonsi M, Dupont S, Maretto S et al. Emilin1 links TGF-β maturation to blood pressure homeostasis. Cell 2006;124:929-42.
18. Zanetti M, Braghetta P, Sabatelli P, Mura I, Doliana R, Colombatti A et al. EMILIN-1 deficiency induces elastogenesis and vascular cell defects. Mol Cell Biol 2004;24:638-50.
19. Ferdous Z, Wei VM, Iozzo R, Höök M, Grande-Allen KJ. Decorin-transforming growth factor-β interaction regulates matrix organization and mechanical characteristics of three-dimensional collagen matrices. J Biol Chem 2007;282:35887-98.
20. Matt P, Fu Z, Carrel T, Huso DL, Dirnhofer S, Lefkovits I et al. Proteomic alterations in heat shock protein 27 and identification of phosphoproteins in ascending aortic aneurysm associated with bicuspid and tricuspid aortic valve. J Mol Cell Cardiol 2007;43:792-801.
21. Jia Y, Ransom RF, Shibanuma M, Liu C, Welsh MJ, Smoyer WE. Identification and characterization of hic-5/ARA55 as an hsp27 binding protein. J Biol Chem 2001;276:39911-18.