Influence of sensitization on the discriminative stimulus effects of methylphenidate in mice

Behavioural Pharmacology

Volumn 25, Issue 8, 2014, Pages 766-774

  McGovern, Robin ^a   Luderman, Lauryn ^a   Knecht, Kelly ^a   Griffin, William C ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

Drug discrimination; Methylphenidate; Mouse; Sensitization

Indexed keywords

METHYLPHENIDATE; CENTRAL STIMULANT AGENT;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DISCRIMINATIVE STIMULUS; DRUG DISCRIMINATION; DRUG EXPOSURE; DRUG SENSITIZATION; LOCOMOTION; MOUSE; NEUROTRANSMISSION; NONHUMAN; REINFORCEMENT; ANALYSIS OF VARIANCE; ANIMAL; C57BL MOUSE; DOSE RESPONSE; DRUG EFFECTS; FOOD PREFERENCE; INSTRUMENTAL CONDITIONING; MOTOR ACTIVITY; PERCEPTIVE DISCRIMINATION;

ANALYSIS OF VARIANCE; ANIMALS; CENTRAL NERVOUS SYSTEM STIMULANTS; CONDITIONING, OPERANT; DISCRIMINATION (PSYCHOLOGY); DOSE-RESPONSE RELATIONSHIP, DRUG; FOOD PREFERENCES; METHYLPHENIDATE; MICE; MICE, INBRED C57BL; MOTOR ACTIVITY;

EID: 84928170385     PISSN: 09558810     EISSN: 14735849     Source Type: Journal    
DOI: 10.1097/FBP.0000000000000095     Document Type: Article

References (68)

1. Askenasy EP, Taber KH, Yang PB, Dafny N (2007). Methylphenidate (Ritalin): behavioral studies in the rat. Int J Neurosci 117:757-794.
2. Balcioglu A, Ren JQ, McCarthy D, Spencer TJ, Biederman J, Bhide PG (2009). Plasma and brain concentrations of oral therapeutic doses of methylphenidate and their impact on brain monoamine content in mice. Neuropharmacology 57:687-693.
3. Becker HC, Crissman AM, Studders S, Kelley BM, Middaugh LD (2004). Differential neurosensitivity to the discriminative stimulus properties of ethanol in C57BL/6J and C3H/He mice. Alcohol Clin Exp Res 28:712-719.
4. Becker H, Griffin W, Lopez M (2013). Neuroadaptive changes that result from chronic drug exposure. In: Miller P, editor. Biological research on addiction: comprehensive addictive behaviors and disorders, edn. 2: Elsevier, Oxford, UK. pp. 169-179.
5. Bell GH, Griffin WC III, Patrick KS (2011). Oral and transdermal DLmethylphenidate- ethanol interactions in C57BL/6J mice: potentiation of locomotor activity with oral delivery. Pharmacol Biochem Behav 100:264-270.
6. Berridge CW, Devilbiss DM, Andrzejewski ME, Arnsten AF, Kelley AE, Schmeichel B, et al. (2006). Methylphenidate preferentially increases catecholamine neurotransmission within the prefrontal cortex at low doses that enhance cognitive function. Biol Psychiatry 60:1111-1120.
7. Besheer J, Cox AA, Hodge CW (2003). Coregulation of ethanol discrimination by the nucleus accumbens and amygdala. Alcohol Clin Exp Res 27:450-456.
8. Besheer J, Palmatier MI, Metschke DM, Bevins RA (2004). Nicotine as a signal for the presence or absence of sucrose reward: a Pavlovian drug appetitive conditioning preparation in rats. Psychopharmacology (Berl) 172:108-117.
9. Besheer J, Fisher KR, Durant B (2012). Assessment of the interoceptive effects of alcohol in rats using short-term training procedures. Alcohol 46:747-755.
10. Biederman J, Spencer T (2002). Methylphenidate in treatment of adults with attention-deficit/hyperactivity disorder. J Atten Disord 6 (Suppl 1): S101-S107.
11. Biederman J, Faraone SV (2005). Attention-deficit hyperactivity disorder. Lancet 366:237-248.
12. Bondareva TS, Young R, Glennon RA (2002). Central stimulants as discriminative stimuli. Asymmetric generalization between (-)ephedrine and S(+ )methamphetamine. Pharmacol Biochem Behav 74:157-162.
13. Brookshire BR, Jones SR (2012). Chronic methylphenidate administration in mice produces depressive-like behaviors and altered responses to fluoxetine. Synapse 66:844-847.
14. Calipari ES, Ferris MJ, Melchior JR, Bermejo K, Salahpour A, Roberts DC, et al. (2014). Methylphenidate and cocaine self-administration produce distinct dopamine terminal alterations. Addict Biol 19:145-155.
15. Crissman AM, Studders SL, Becker HC (2004). Tolerance to the discriminative stimulus effects of ethanol following chronic inhalation exposure to ethanol in C57BL/6J mice. Behav Pharmacol 15:569-575.
16. Czoty PW, Makriyannis A, Bergman J (2004). Methamphetamine discrimination and in vivo microdialysis in squirrel monkeys. Psychopharmacology (Berl) 175:170-178.
17. Darredeau C, Barrett SP, Jardin B, Pihl RO (2007). Patterns and predictors of medication compliance, diversion, and misuse in adult prescribed methylphenidate users. Hum Psychopharmacol 22:529-536.
18. Desai RI, Paronis CA, Martin J, Desai R, Bergman J (2010). Monoaminergic psychomotor stimulants: discriminative stimulus effects and dopamine efflux. J Pharmacol Exp Ther 333:834-843.
19. Duke AN, Bigelow GE, Lanier RK, Strain EC (2011). Discriminative stimulus effects of tramadol in humans. J Pharmacol Exp Ther 338:255-262.
20. Ferris MJ, Calipari ES, Mateo Y, Melchior JR, Roberts DC, Jones SR (2012). Cocaine self-administration produces pharmacodynamic tolerance: differential effects on the potency of dopamine transporter blockers, releasers, and methylphenidate. Neuropsychopharmacology 37:1708-1716.
21. Godfrey J (2009). Safety of therapeutic methylphenidate in adults: a systematic review of the evidence. J Psychopharmacol 23:194-205.
22. Greenberg I, Kuhn DM, Appel JB (1975). Behaviorally induced sensitivity to the discriminable properties of LSD. Psychopharmacologia 43:229-232.
23. Griffin WC III, Middaugh LD (2006). The influence of sex on extracellular dopamine and locomotor activity in C57BL/6J mice before and after acute cocaine challenge. Synapse 59:74-81.
24. Griffin WC III, Novak AJ, Middaugh LD, Patrick KS (2010). The interactive effects of methylphenidate and ethanol on ethanol consumption and locomotor activity in mice. Pharmacol Biochem Behav 95:267-272.
25. Griffin WC III, Nguyen SA, Deleon CP, Middaugh LD (2012). Effects of vigabatrin, an irreversible GABA transaminase inhibitor, on ethanol reinforcement and ethanol discriminative stimuli in mice. Behav Pharmacol 23:178-190.
26. Griffin WC III, McGovern RW, Bell GH, Randall PK, Middaugh LD, Patrick KS (2013). Interactive effects of methylphenidate and alcohol on discrimination, conditioned place preference and motor coordination in C57BL/6J mice. Psychopharmacology (Berl) 225:613-625.
27. Hammerness P, Joshi G, Doyle R, Georgiopoulos A, Geller D, Spencer T, et al. (2013). Do stimulants reduce the risk for cigarette smoking in youth with attention-deficit hyperactivity disorder? A prospective, long-term, open-label study of extended-release methylphenidate. J Pediatr 162:22-27.
28. Heil SH, Holmes HW, Bickel WK, Higgins ST, Badger GJ, Laws HF, Faries DE (2002). Comparison of the subjective, physiological, and psychomotor effects of atomoxetine and methylphenidate in light drug users. Drug Alcohol Depend 67:149-156.
29. Hodge CW, Alken AS (1996). Discriminative stimulus function of ethanol: role of GABAA receptors in the nucleus accumbens. Alcohol Clin Exp Res 20:1221-1228.
30. Hodge CW, Cox AA (1998). The discriminative stimulus effects of ethanol are mediated by NMDA and GABA(A) receptors in specific limbic brain regions. Psychopharmacology (Berl) 139:95-107.
31. Jones Z, Dafny N (2013). Dose response effect of methylphenidate on ventral tegmental area neurons and animal behavior. Brain Res Bull 96:86-92.
32. Koda K, Ago Y, Cong Y, Kita Y, Takuma K, Matsuda T (2010). Effects of acute and chronic administration of atomoxetine and methylphenidate on extracellular levels of noradrenaline, dopamine and serotonin in the prefrontal cortex and striatum of mice. J Neurochem 114:259-270.
33. Kollins SH, MacDonald EK, Rush CR (2001). Assessing the abuse potential of methylphenidate in nonhuman and human subjects: a review. Pharmacol Biochem Behav 68:611-627.
34. Kollins SH, English J, Robinson R, Hallyburton M, Chrisman AK (2009). Reinforcing and subjective effects of methylphenidate in adults with and without attention deficit hyperactivity disorder (ADHD). Psychopharmacology (Berl) 204:73-83.
35. Kroutil LA, Van Brunt DL, Herman-Stahl MA, Heller DC, Bray RM, Penne MA (2006). Nonmedical use of prescription stimulants in the United States. Drug Alcohol Depend 84:135-143.
36. Kuczenski R, Segal DS (1997). Effects of methylphenidate on extracellular dopamine, serotonin, and norepinephrine: comparison with amphetamine. J Neurochem 68:2032-2037.
37. Kuczenski R, Segal DS (2001). Locomotor effects of acute and repeated threshold doses of amphetamine and methylphenidate: relative roles of dopamine and norepinephrine. J Pharmacol Exp Ther 296:876-883.
38. Kuczenski R, Segal DS (2005). Stimulant actions in rodents: implications for attention-deficit/hyperactivity disorder treatment and potential substance abuse. Biol Psychiatry 57:1391-1396.
39. Lee MJ, Swann AC, Dafny N (2008). Methylphenidate sensitization is prevented by prefrontal cortex lesion. Brain Res Bull 76:131-140.
40. Leyton M (2007). Conditioned and sensitized responses to stimulant drugs in humans. Prog Neuropsychopharmacol Biol Psychiatry 31:1601-1613.
41. Li SM, Campbell BL, Katz JL (2006). Interactions of cocaine with dopamine uptake inhibitors or dopamine releasers in rats discriminating cocaine. J Pharmacol Exp Ther 317:1088-1096.
42. Lile JA, Stoops WW, Durell TM, Glaser PE, Rush CR (2006). Discriminativestimulus, self-reported, performance, and cardiovascular effects of atomoxetine in methylphenidate-trained humans. Exp Clin Psychopharmacol 14:136-147.
43. McCabe SE, Teter CJ, Boyd CJ, Guthrie SK (2004). Prevalence and correlates of illicit methylphenidate use among 8th, 10th, and 12th grade students in the United States, 2001. J Adolesc Health 35:501-504.
44. McCabe SE, Cranford JA, Morales M, Young A (2006). Simultaneous and concurrent polydrug use of alcohol and prescription drugs: prevalence, correlates, and consequences. J Stud Alcohol 67:529-537.
45. McGovern RW, Middaugh LD, Patrick KS, Griffin WC III (2011). The discriminative stimulus properties of methylphenidate in C57BL/6J mice. Behav Pharmacol 22:14-22.
46. McKim WA (1976). The effects of pre-exposure to scopolamine on subsequent drug state discrimination. Psychopharmacologia 47:153-155.
47. Novak SP, Kroutil LA, Williams RL, Van Brunt DL (2007). The nonmedical use of prescription ADHD medications: results from a national Internet panel. Subst Abuse Treat Prev Policy 2:32.
48. Overton DA, Shen CF (1988). Comparison of four-drug discriminations in training compartments with four identical levers versus four different responses manipulanda. Pharmacol Biochem Behav 30:879-888.
49. Palmatier MI, Peterson JL, Wilkinson JL, Bevins RA (2004). Nicotine serves as a feature-positive modulator of Pavlovian appetitive conditioning in rats. Behav Pharmacol 15:183-194.
50. Patrick KS, Straughn AB, Minhinnett RR, Yeatts SD, Herrin AE, DeVane CL, et al. (2007). Influence of ethanol and gender on methylphenidate pharmacokinetics and pharmacodynamics. Clin Pharmacol Ther 81:346-353.
51. Perkins AN, Eckerman DA, MacPhail RC (1991). Discriminative stimulus properties of triadimefon: comparison with methylphenidate. Pharmacol Biochem Behav 40:757-761.
52. Robinson TE, Berridge KC (1993). The neural basis of drug craving: an incentivesensitization theory of addiction. Brain Res Brain Res Rev 18:247-291.
53. Robinson TE, Berridge KC (2001). Incentive-sensitization and addiction. Addiction 96:103-114.
54. Rush CR, Kelly TH, Hays LR, Wooten AF (2002). Discriminative-stimulus effects of modafinil in cocaine-trained humans. Drug Alcohol Depend 67:311-322.
55. Sannerud CA, Young AM (1987). Environmental modification of tolerance to morphine discriminative stimulus properties in rats. Psychopharmacology (Berl) 93:59-68.
56. Schweri MM, Deutsch HM, Massey AT, Holtzman SG (2002). Biochemical and behavioral characterization of novel methylphenidate analogs. J Pharmacol Exp Ther 301:527-535.
57. Sevak RJ, Stoops WW, Hays LR, Rush CR (2009). Discriminative stimulus and subject-rated effects of methamphetamine, D-amphetamine, methylphenidate, and triazolam in methamphetamine-trained humans. J Pharmacol Exp Ther 328:1007-1018.
58. Smith JW, Stolerman IP (2009). Recognising nicotine: the neurobiological basis of nicotine discrimination. Handb Exp Pharmacol295-333.
59. Stolerman IP, Childs E, Ford MM, Grant KA (2011). Role of training dose in drug discrimination: a review. Behav Pharmacol 22:415-429.
60. Stoops WW, Lile JA, Fillmore MT, Glaser PE, Rush CR (2005a). Reinforcing effects of methylphenidate: influence of dose and behavioral demands following drug administration. Psychopharmacology (Berl) 177:349-355.
61. Stoops WW, Lile JA, Glaser PE, Rush CR (2005b). Discriminative stimulus and self-reported effects of methylphenidate, d-amphetamine, and triazolam in methylphenidate-trained humans. Exp Clin Psychopharmacol 13:56-64.
62. Suzuki T, Fukuoka Y, Mori T, Miyatake M, Narita M (2004). Behavioral sensitization to the discriminative stimulus effects of methamphetamine in rats. Eur J Pharmacol 498:157-161.
63. Teter CJ, McCabe SE, Boyd CJ, Guthrie SK (2003). Illicit methylphenidate use in an undergraduate student sample: prevalence and risk factors. Pharmacotherapy 23:609-617.
64. Vezina P, Leyton M (2009). Conditioned cues and the expression of stimulant sensitization in animals and humans. Neuropharmacology 56 (Suppl 1):160-168.
65. Williard RL, Middaugh LD, Zhu HJ, Patrick KS (2007). Methylphenidate and its ethanol transesterification metabolite ethylphenidate: brain disposition, monoamine transporters and motor activity. Behav Pharmacol 18:39-51.
66. Yang PB, Swann AC, Dafny N (2007). Chronic administration of methylphenidate produces neurophysiological and behavioral sensitization. Brain Res 1145:66-80.
67. Yang PB, Atkins KD, Dafny N (2011). Behavioral sensitization and crosssensitization between methylphenidate amphetamine, and 3,4-methylenedioxymethamphetamine (MDMA) in female SD rats. Eur J Pharmacol 661:72-85.
68. Young AM, McMullen WJ, Makhay MM, Goushaw PJ (1996). Behavioral contingencies modulate tolerance to discriminative stimulus effects of morphine. Psychopharmacology (Berl) 125:220-230.