메뉴 건너뛰기




Volumn 409, Issue , 2015, Pages 41-50

Activin-βC modulates gonadal, but not adrenal tumorigenesis in the inhibin deficient mice

Author keywords

Adrenal; Gonadectomy; Inhibin; Ovaries; Testis; Tumor

Indexed keywords

ACTIVIN; ACTIVIN A; ACTIVIN BETA SUBUNIT C; ACTIVIN RECEPTOR 2; ACTIVIN RECEPTOR 2B; FOLLISTATIN; INHIBIN; SMAD2 PROTEIN; UNCLASSIFIED DRUG; INHBC PROTEIN, MOUSE; INHIBIN BETA A SUBUNIT;

EID: 84928121807     PISSN: 03037207     EISSN: 18728057     Source Type: Journal    
DOI: 10.1016/j.mce.2015.04.004     Document Type: Article
Times cited : (9)

References (37)
  • 1
    • 0034039316 scopus 로고    scopus 로고
    • Expression of inhibin alpha in adrenocortical tumours reflects the hormonal status of the neoplasm
    • Arola J., Liu J., Heikkila P., Ilvesmaki V., Salmenkivi K., Voutilainen R., et al. Expression of inhibin alpha in adrenocortical tumours reflects the hormonal status of the neoplasm. J. Endocrinol 2000, 165:223-229.
    • (2000) J. Endocrinol , vol.165 , pp. 223-229
    • Arola, J.1    Liu, J.2    Heikkila, P.3    Ilvesmaki, V.4    Salmenkivi, K.5    Voutilainen, R.6
  • 2
    • 0037907682 scopus 로고    scopus 로고
    • Activin induces x-zone apoptosis that inhibits luteinizing hormone-dependent adrenocortical tumor formation in inhibin-deficient mice
    • Beuschlein F., Looyenga B.D., Bleasdale S.E., Mutch C., Bavers D.L., Parlow A.F., et al. Activin induces x-zone apoptosis that inhibits luteinizing hormone-dependent adrenocortical tumor formation in inhibin-deficient mice. Mol. Cell. Biol 2003, 23:3951-3964.
    • (2003) Mol. Cell. Biol , vol.23 , pp. 3951-3964
    • Beuschlein, F.1    Looyenga, B.D.2    Bleasdale, S.E.3    Mutch, C.4    Bavers, D.L.5    Parlow, A.F.6
  • 3
    • 3142670448 scopus 로고    scopus 로고
    • Role of the inhibin/activin system and luteinizing hormone in adrenocortical tumorigenesis
    • Beuschlein F., Looyenga B., Reincke M., Hammer G. Role of the inhibin/activin system and luteinizing hormone in adrenocortical tumorigenesis. Horm. Metab. Res 2004, 36:392-396.
    • (2004) Horm. Metab. Res , vol.36 , pp. 392-396
    • Beuschlein, F.1    Looyenga, B.2    Reincke, M.3    Hammer, G.4
  • 4
    • 0027465121 scopus 로고
    • Phase II trial of mitotane and cisplatin in patients with adrenal carcinoma: a Southwest Oncology Group study
    • Bukowski R.M., Wolfe M., Levine H.S., Crawford D.E., Stephens R.L., Gaynor E., et al. Phase II trial of mitotane and cisplatin in patients with adrenal carcinoma: a Southwest Oncology Group study. J. Clin. Oncol 1993, 11:161-165.
    • (1993) J. Clin. Oncol , vol.11 , pp. 161-165
    • Bukowski, R.M.1    Wolfe, M.2    Levine, H.S.3    Crawford, D.E.4    Stephens, R.L.5    Gaynor, E.6
  • 5
    • 0034035714 scopus 로고    scopus 로고
    • Immunoexpression of Inhibin α Subunit, Inhibin/Activin βA Subunit and CD99 in Ovarian Tumors
    • Choi Y.-L., Kim H.-S., Ahn G. Immunoexpression of Inhibin α Subunit, Inhibin/Activin βA Subunit and CD99 in Ovarian Tumors. Arch. Pathol. Lab. Med 2000, 124:563-569.
    • (2000) Arch. Pathol. Lab. Med , vol.124 , pp. 563-569
    • Choi, Y.-L.1    Kim, H.-S.2    Ahn, G.3
  • 6
    • 80055073369 scopus 로고    scopus 로고
    • Trafficking of hepatitis C virus core protein during virus particle assembly
    • Counihan N.A., Rawlinson S.M., Lindenbach B.D. Trafficking of hepatitis C virus core protein during virus particle assembly. PLoS Pathog 2011, 7:e1002302.
    • (2011) PLoS Pathog , vol.7 , pp. e1002302
    • Counihan, N.A.1    Rawlinson, S.M.2    Lindenbach, B.D.3
  • 8
    • 15744372725 scopus 로고    scopus 로고
    • Role of transforming growth factor beta in human cancer
    • Elliott R.L., Blobe G.C. Role of transforming growth factor beta in human cancer. J. Clin. Oncol 2005, 23:2078-2093.
    • (2005) J. Clin. Oncol , vol.23 , pp. 2078-2093
    • Elliott, R.L.1    Blobe, G.C.2
  • 9
    • 0026648674 scopus 로고
    • Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
    • Gavrieli Y., Sherman Y., Ben-Sasson S.A. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J. Cell Biol 1992, 119:493-501.
    • (1992) J. Cell Biol , vol.119 , pp. 493-501
    • Gavrieli, Y.1    Sherman, Y.2    Ben-Sasson, S.A.3
  • 10
    • 58249110402 scopus 로고    scopus 로고
    • Activin C antagonizes activin A in vitro and overexpression leads to pathologies in vivo
    • Gold E., Jetly N., O'Bryan M.K., Meachem S., Srinivasan D., Behuria S., et al. Activin C antagonizes activin A in vitro and overexpression leads to pathologies in vivo. Am. J. Pathol 2009, 174:184-195.
    • (2009) Am. J. Pathol , vol.174 , pp. 184-195
    • Gold, E.1    Jetly, N.2    O'Bryan, M.K.3    Meachem, S.4    Srinivasan, D.5    Behuria, S.6
  • 11
    • 84874107500 scopus 로고    scopus 로고
    • Activin-βc reduces reproductive tumour progression and abolishes cancer-associated cachexia in inhibin-deficient mice
    • Gold E., Marino F.E., Harrison C., Makanji Y., Risbridger G. Activin-βc reduces reproductive tumour progression and abolishes cancer-associated cachexia in inhibin-deficient mice. J. Pathol 2013, 229:599-607.
    • (2013) J. Pathol , vol.229 , pp. 599-607
    • Gold, E.1    Marino, F.E.2    Harrison, C.3    Makanji, Y.4    Risbridger, G.5
  • 12
    • 17844409870 scopus 로고    scopus 로고
    • BetaA- and betaC-activin, follistatin, activin receptor mRNA and betaC-activin peptide expression during rat liver regeneration
    • Gold E.J., Zhang X., Wheatley A.M., Mellor S.L., Cranfield M., Risbridger G.P., et al. betaA- and betaC-activin, follistatin, activin receptor mRNA and betaC-activin peptide expression during rat liver regeneration. J. Mol. Endocrinol 2005, 34:505-515.
    • (2005) J. Mol. Endocrinol , vol.34 , pp. 505-515
    • Gold, E.J.1    Zhang, X.2    Wheatley, A.M.3    Mellor, S.L.4    Cranfield, M.5    Risbridger, G.P.6
  • 14
    • 84860715070 scopus 로고    scopus 로고
    • Inhibins and activins: their roles in the adrenal gland and the development of adrenocortical tumors
    • Hofland J., de Jong F.H. Inhibins and activins: their roles in the adrenal gland and the development of adrenocortical tumors. Mol. Cell. Endocrinol 2012, 359:92-100.
    • (2012) Mol. Cell. Endocrinol , vol.359 , pp. 92-100
    • Hofland, J.1    de Jong, F.H.2
  • 16
    • 0033624022 scopus 로고    scopus 로고
    • Activin βC and βE genes are not essential for mouse liver growth, differentiation, and regeneration
    • Lau A.L., Kumar T.R., Nishimori K., Bonadio J., Matzuk M.M. Activin βC and βE genes are not essential for mouse liver growth, differentiation, and regeneration. Mol. Cell. Biol 2000, 20:6127-6137.
    • (2000) Mol. Cell. Biol , vol.20 , pp. 6127-6137
    • Lau, A.L.1    Kumar, T.R.2    Nishimori, K.3    Bonadio, J.4    Matzuk, M.M.5
  • 17
    • 0006000627 scopus 로고
    • Isolation and partial characterization of a Mr 32,000 protein with inhibin activity from porcine follicular fluid
    • Ling N., Ying S.Y., Ueno N., Esch F., Denoroy L., Guillemin R. Isolation and partial characterization of a Mr 32,000 protein with inhibin activity from porcine follicular fluid. PNAS 1985, 82:7217-7221.
    • (1985) PNAS , vol.82 , pp. 7217-7221
    • Ling, N.1    Ying, S.Y.2    Ueno, N.3    Esch, F.4    Denoroy, L.5    Guillemin, R.6
  • 18
    • 0001531986 scopus 로고
    • Clinical and pathophysiologic aspects of adrenocortical carcinoma
    • Lipsett M.B., Hertz R., Ross G.T. Clinical and pathophysiologic aspects of adrenocortical carcinoma. Am. J. Med 1963, 35:374-383.
    • (1963) Am. J. Med , vol.35 , pp. 374-383
    • Lipsett, M.B.1    Hertz, R.2    Ross, G.T.3
  • 19
    • 33751503705 scopus 로고    scopus 로고
    • Origin and identity of adrenocortical tumors in inhibin knockout mice: implications for cellular plasticity in the adrenal cortex
    • Looyenga B.D., Hammer G.D. Origin and identity of adrenocortical tumors in inhibin knockout mice: implications for cellular plasticity in the adrenal cortex. Mol. Endocrinol 2006, 20:2848-2863.
    • (2006) Mol. Endocrinol , vol.20 , pp. 2848-2863
    • Looyenga, B.D.1    Hammer, G.D.2
  • 20
    • 77249134230 scopus 로고    scopus 로고
    • Inhibin-A antagonizes TGFβ2 signaling by down-regulating cell surface expression of the TGFβ coreceptor betaglycan
    • Looyenga B.D., Wiater E., Vale W., Hammer G.D. Inhibin-A antagonizes TGFβ2 signaling by down-regulating cell surface expression of the TGFβ coreceptor betaglycan. Mol. Endocrinol 2010, 24:608-620.
    • (2010) Mol. Endocrinol , vol.24 , pp. 608-620
    • Looyenga, B.D.1    Wiater, E.2    Vale, W.3    Hammer, G.D.4
  • 21
    • 84899670282 scopus 로고    scopus 로고
    • Islet1 and its co-factor Ldb1 are expressed in quiescent cells of mouse intestinal epithelium
    • Makarev E., Gorivodsky M. Islet1 and its co-factor Ldb1 are expressed in quiescent cells of mouse intestinal epithelium. PLoS ONE 2014, 9:e95256.
    • (2014) PLoS ONE , vol.9 , pp. e95256
    • Makarev, E.1    Gorivodsky, M.2
  • 23
    • 84928110139 scopus 로고    scopus 로고
    • The inhibin/activin signalling pathway in human gonadal and adrenal cancers
    • Marino F.E., Risbridger G., Gold E. The inhibin/activin signalling pathway in human gonadal and adrenal cancers. Mol. Hum. Reprod 2014, 20:1223-1237.
    • (2014) Mol. Hum. Reprod , vol.20 , pp. 1223-1237
    • Marino, F.E.1    Risbridger, G.2    Gold, E.3
  • 24
    • 0031685620 scopus 로고    scopus 로고
    • TGF-β signal transduction
    • Massagué J. TGF-β signal transduction. Annu. Rev. Biochem 1998, 67:753-791.
    • (1998) Annu. Rev. Biochem , vol.67 , pp. 753-791
    • Massagué, J.1
  • 25
    • 0034574298 scopus 로고    scopus 로고
    • How cells read TGF-[beta] signals
    • Massague J. How cells read TGF-[beta] signals. Nat. Rev. Mol. Cell Biol 2000, 1:169-178.
    • (2000) Nat. Rev. Mol. Cell Biol , vol.1 , pp. 169-178
    • Massague, J.1
  • 26
    • 0028557211 scopus 로고
    • Development of cancer cachexia-like syndrome and adrenal tumors in inhibin-deficient mice
    • Matzuk M., Finegold M., Mather J., Krummen L., Lu H., Bradley A. Development of cancer cachexia-like syndrome and adrenal tumors in inhibin-deficient mice. PNAS 1994, 91:8817-8821.
    • (1994) PNAS , vol.91 , pp. 8817-8821
    • Matzuk, M.1    Finegold, M.2    Mather, J.3    Krummen, L.4    Lu, H.5    Bradley, A.6
  • 27
    • 0026621796 scopus 로고
    • Alpha-Inhibin is a tumour-suppressor gene with gonadal specificity in mice
    • Matzuk M.M., Finegold M.J., Su J.-G.J., Hsueh A.J.W., Bradley A. alpha-Inhibin is a tumour-suppressor gene with gonadal specificity in mice. Nature 1992, 360:313-319.
    • (1992) Nature , vol.360 , pp. 313-319
    • Matzuk, M.M.1    Finegold, M.J.2    Su, J.-G.J.3    Hsueh, A.J.W.4    Bradley, A.5
  • 28
    • 77649253043 scopus 로고    scopus 로고
    • Estrogen receptor-β activated apoptosis in benign hyperplasia and cancer of the prostate is androgen independent and TNFα mediated
    • McPherson S.J., Hussain S., Balanathan P., Hedwards S.L., Niranjan B., Grant M., et al. Estrogen receptor-β activated apoptosis in benign hyperplasia and cancer of the prostate is androgen independent and TNFα mediated. PNAS 2010, 107:3123-3128.
    • (2010) PNAS , vol.107 , pp. 3123-3128
    • McPherson, S.J.1    Hussain, S.2    Balanathan, P.3    Hedwards, S.L.4    Niranjan, B.5    Grant, M.6
  • 29
    • 0034487730 scopus 로고    scopus 로고
    • Localization of activin βA-,β B-, and β C-subunits in human prostate and evidence for formation of new activin heterodimers of β C-subunit
    • Mellor S.L., Cranfield M., Ries R., Pedersen J., Cancilla B., De Kretser D., et al. Localization of activin βA-,β B-, and β C-subunits in human prostate and evidence for formation of new activin heterodimers of β C-subunit. J. Clin. Endocrinol. Metab 2000, 85:4851-4858.
    • (2000) J. Clin. Endocrinol. Metab , vol.85 , pp. 4851-4858
    • Mellor, S.L.1    Cranfield, M.2    Ries, R.3    Pedersen, J.4    Cancilla, B.5    De Kretser, D.6
  • 33
    • 0026704725 scopus 로고
    • Activin and inhibin in the human adrenal gland. Regulation and differential effects in fetal and adult cells
    • Spencer S.J., Rabinovici J., Mesiano S., Goldsmith P.C., Jaffe R.B. Activin and inhibin in the human adrenal gland. Regulation and differential effects in fetal and adult cells. J. Clin. Invest 1992, 90:1420149.
    • (1992) J. Clin. Invest , vol.90 , pp. 1420149
    • Spencer, S.J.1    Rabinovici, J.2    Mesiano, S.3    Goldsmith, P.C.4    Jaffe, R.B.5
  • 34
    • 0033031741 scopus 로고    scopus 로고
    • Proliferation and apoptosis in the human adrenal cortex during the fetal and perinatal periods: implications for growth and remodeling 1
    • Spencer S.J., Mesiano S., Lee J.Y., Jaffe R.B. Proliferation and apoptosis in the human adrenal cortex during the fetal and perinatal periods: implications for growth and remodeling 1. The J. Clin. Endocrinol. Metab 1999, 84:1110-1115.
    • (1999) The J. Clin. Endocrinol. Metab , vol.84 , pp. 1110-1115
    • Spencer, S.J.1    Mesiano, S.2    Lee, J.Y.3    Jaffe, R.B.4
  • 35
    • 0141842605 scopus 로고    scopus 로고
    • Expression of activin/inhibin signaling components in the human adrenal gland and the effects of activins and inhibins on adrenocortical steroidogenesis and apoptosis
    • Vanttinen T., Liu J., Kuulasmaa T., Kivinen P., Voutilainen R. Expression of activin/inhibin signaling components in the human adrenal gland and the effects of activins and inhibins on adrenocortical steroidogenesis and apoptosis. J. Endocrinol 2003, 178:479-489.
    • (2003) J. Endocrinol , vol.178 , pp. 479-489
    • Vanttinen, T.1    Liu, J.2    Kuulasmaa, T.3    Kivinen, P.4    Voutilainen, R.5
  • 36
    • 0025837068 scopus 로고
    • Hormonally regulated inhibin gene expression in human fetal and adult adrenals
    • Voutilainen R., Erämaa M., Rivtos O. Hormonally regulated inhibin gene expression in human fetal and adult adrenals. J. Clin. Endocrinol. Metab 1991, 73:1026-1030.
    • (1991) J. Clin. Endocrinol. Metab , vol.73 , pp. 1026-1030
    • Voutilainen, R.1    Erämaa, M.2    Rivtos, O.3
  • 37
    • 0027510158 scopus 로고
    • Pharmacokinetic profile of recombinant human (rh) inhibin A and activin A in the immature rat. II. Tissue distribution of [125I] rh-inhibin A and [125I] rh-activin A in immature female and male rats
    • Woodruff T.K., Krummen L., Chen S.A., Lyon R., Hansen S.E., Deguzman G., et al. Pharmacokinetic profile of recombinant human (rh) inhibin A and activin A in the immature rat. II. Tissue distribution of [125I] rh-inhibin A and [125I] rh-activin A in immature female and male rats. Endocrinology 1993, 132:725-734.
    • (1993) Endocrinology , vol.132 , pp. 725-734
    • Woodruff, T.K.1    Krummen, L.2    Chen, S.A.3    Lyon, R.4    Hansen, S.E.5    Deguzman, G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.