α-2,8-sialyltransferase is involved in the development of multidrug resistance via PI3K/Akt pathway in human chronic myeloid leukemia

IUBMB Life

Volumn 67, Issue 2, 2015, Pages 77-87

  Zhang, Xu ^a   Dong, Weijie ^a   Zhou, Huimin ^a   Li, Hongshuai ^a   Wang, Ning ^a   Miao, Xiaoyan ^a   Jia, Li ^a  

^a DALIAN MEDICAL UNIVERSITY   (China)

Author keywords

human leukemia cell line; multidrug resistance; PI3K Akt signal pathway; 2 8 sialyltransferases

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; ALPHA 2,8 SIALYLTRANSFERASE; DOXORUBICIN; MULTIDRUG RESISTANCE PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SIALYLTRANSFERASE; UNCLASSIFIED DRUG; ST8SIA4 PROTEIN, HUMAN; ST8SIA6 PROTEIN, HUMAN;

ADOLESCENT; ADULT; AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER RESISTANCE; CHEMOSENSITIVITY; CHRONIC MYELOID LEUKEMIA; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; FEMALE; GENE; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; MULTIDRUG RESISTANCE; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PHENOTYPE; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; ST8SIA1 GENE; ST8SIA2 GENE; ST8SIA3 GENE; ST8SIA4 GENE; ST8SIA5 GENE; ANIMAL; DRUG RESISTANCE; DRUG SCREENING; GENE EXPRESSION REGULATION; GENETICS; LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE; METABOLISM; MIDDLE AGED; NUDE MOUSE; TUMOR CELL LINE; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; ANIMALS; CELL LINE, TUMOR; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; FEMALE; GENE EXPRESSION REGULATION, LEUKEMIC; HUMANS; LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE; MALE; MICE, NUDE; MIDDLE AGED; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; SIALYLTRANSFERASES; XENOGRAFT MODEL ANTITUMOR ASSAYS; YOUNG ADULT;

EID: 84928109376     PISSN: 15216543     EISSN: 15216551     Source Type: Journal    
DOI: 10.1002/iub.1351     Document Type: Article

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