Activation of autophagy in rats with plateau stress-induced intestinal failure

International Journal of Clinical and Experimental Pathology

Volumn 8, Issue 2, 2015, Pages 1816-1821

  Zhang, Fangxin ^a   Deng, Zhiyun ^a   Li, Wenxiang ^a   Zheng, Xiaofeng ^a   Zhang, Jiucong ^a   Deng, Shangxin ^a   Chen, Jiayu ^a   Ma, Qiang ^a   Wang, Yong ^a   Yu, Xiaohui ^a   Wang, Xiufeng ^a  

^a LANZHOU GENERAL HOSPITAL   (China)

Author keywords

Autophagy; Beclin1; High altitude; Hypoxia; Intestinal failure; LC3B

Indexed keywords

APOPTOSIS REGULATORY PROTEIN; BECLIN 1; BECN1 PROTEIN, RAT; LC3 PROTEIN, RAT; MICROTUBULE ASSOCIATED PROTEIN;

ALTITUDE; ALTITUDE DISEASE; ANIMAL; AUTOPHAGY; COMPLICATION; DISEASE MODEL; INTESTINE MUCOSA; MALE; METABOLISM; PATHOLOGY; TIME FACTOR; TRANSMISSION ELECTRON MICROSCOPY; ULTRASTRUCTURE; WISTAR RAT;

ALTITUDE; ALTITUDE SICKNESS; ANIMALS; APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; BECLIN-1; DISEASE MODELS, ANIMAL; INTESTINAL MUCOSA; MALE; MICROSCOPY, ELECTRON, TRANSMISSION; MICROTUBULE-ASSOCIATED PROTEINS; RATS, WISTAR; TIME FACTORS;

EID: 84928104175     PISSN: None     EISSN: 19362625     Source Type: Journal    
DOI: None     Document Type: Article

References (11)

1. Netzer N, Strohl K, Faulhaber M, Gatterer H, Burtscher M. Hypoxia-related altitude illnesses. J Travel Med 2013; 20: 247-255.
2. Wu TY, Ding SQ, Liu JL, Jia JH, Dai RC, Zhu DC, Liang BZ, Qi DT, Sun YF. High-altitude gastrointestinal bleeding: an observation in Qinghai-Tibetan railroad construction workers on Mountain Tanggula. World J Gastroenterol 2007; 13: 774-780.
3. Kroemer G, Marino G, Levine B. Autophagy and the integrated stress response. Mol Cell 2010; 40: 280-293.
4. Jiang P, Mizushima N. Autophagy and human diseases. Cell Res 2014; 24: 69-79.
5. Yang DZ, Zhou QQ, Li SZ, Liu FU. Intestial mucosal barrier dysfuction injury induced by altitude hypoxia in rats and the protective effect of glutamine. Med J Chin PLA 2011; 36: 301-306.
6. Zhou QQ, Yang DZ, Luo YJ, Li SZ, Liu FY, Wang GS. Over-starvation aggravates intestinal injury and promotes bacterial and endotoxin translocation under high-altitude hypoxic environment. World J Gastroenterol 2011; 17: 1584-1593.
7. Zhang FX, Deng ZY, Dong JZ, Duan Y, Deng SX, Chen JY, Ma Q, Shan TD. Effects of Prebiotics on the Expression of the Integral Membrane Protein Occludin and Cytokines in Rats after Acute High Altitude Exposure. Int J Pharmacol 2013; 9: 385-389.
8. Velasco N. [Gut barrier in the critically ill patient: facts and trends]. Rev Med Chil 2006; 134: 1033-1039.
9. Yoshizaki T, Kusunoki C, Kondo M, Yasuda M, Kume S, Morino K, Sekine O, Ugi S, Uzu T, Nishio Y, Kashiwagi A, Maegawa H. Autophagy regulates inflammation in adipocytes. Biochem Biophys Res Commun 2012; 417: 352-357.
10. Wirawan E, Lippens S, Vanden Berghe T, Romagnoli A, Fimia GM, Piacentini M, Vandenabeele P. Beclin1: a role in membrane dynamics and beyond. Autophagy 2012; 8: 6-17.
11. Ni HM, Bockus A, Wozniak AL, Jones K, Weinman S, Yin XM, Ding WX. Dissecting the dynamic turnover of GFP-LC3 in the autolysosome. Autophagy 2011; 7: 188-204.