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Volumn 39, Issue 5, 2015, Pages 520-524

Discontinuation of hypomethylating agent therapy in patients with myelodysplastic syndromes or acute myelogenous leukemia in complete remission or partial response: Retrospective analysis of survival after long-term follow-up

Author keywords

Hypomethylating agents; Myelodysplastic syndromes; Treatment discontinuation

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; AZACITIDINE; HYPOMETHYLATING AGENT; UNCLASSIFIED DRUG; ANTINEOPLASTIC ANTIMETABOLITE; DECITABINE;

EID: 84928052699     PISSN: 01452126     EISSN: 18735835     Source Type: Journal    
DOI: 10.1016/j.leukres.2015.03.006     Document Type: Article
Times cited : (46)

References (17)
  • 1
    • 33646071894 scopus 로고    scopus 로고
    • Decitabine improves patient outcomes in myelodysplastic syndromes: results of a phase III randomized study
    • Kantarjian H., Issa J.P., Rosenfeld C.S., Bennett J.M., Albitar M., DiPersio J., et al. Decitabine improves patient outcomes in myelodysplastic syndromes: results of a phase III randomized study. Cancer 2006, 106:1794-1803.
    • (2006) Cancer , vol.106 , pp. 1794-1803
    • Kantarjian, H.1    Issa, J.P.2    Rosenfeld, C.S.3    Bennett, J.M.4    Albitar, M.5    DiPersio, J.6
  • 2
    • 10744233452 scopus 로고    scopus 로고
    • Phase 1 study of low-dose prolonged exposure schedules of the hypomethylating agent 5-aza-2'-deoxycytidine (decitabine) in hematopoietic malignancies
    • Issa J.P., Garcia-Manero G., Giles F.J., Mannari R., Thomas D., Faderl S., et al. Phase 1 study of low-dose prolonged exposure schedules of the hypomethylating agent 5-aza-2'-deoxycytidine (decitabine) in hematopoietic malignancies. Blood 2004, 103:1635-1640.
    • (2004) Blood , vol.103 , pp. 1635-1640
    • Issa, J.P.1    Garcia-Manero, G.2    Giles, F.J.3    Mannari, R.4    Thomas, D.5    Faderl, S.6
  • 3
    • 62849104641 scopus 로고    scopus 로고
    • Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes: a randomised, open-label, phase III study
    • Fenaux P., Mufti G.J., Hellstrom-Lindberg E., Santini V., Finelli C., Giagounidis A., et al. Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes: a randomised, open-label, phase III study. Lancet Oncol 2009, 10:223-232.
    • (2009) Lancet Oncol , vol.10 , pp. 223-232
    • Fenaux, P.1    Mufti, G.J.2    Hellstrom-Lindberg, E.3    Santini, V.4    Finelli, C.5    Giagounidis, A.6
  • 4
    • 84864063679 scopus 로고    scopus 로고
    • Multicenter, randomized, open-label, phase III trial of decitabine versus patient choice, with physician advice, of either supportive care or low-dose cytarabine for the treatment of older patients with newly diagnosed acute myeloid leukemia
    • Kantarjian H.M., Thomas X.G., Dmoszynska A., Wierzbowska A., Mazur G., Mayer J., et al. Multicenter, randomized, open-label, phase III trial of decitabine versus patient choice, with physician advice, of either supportive care or low-dose cytarabine for the treatment of older patients with newly diagnosed acute myeloid leukemia. J Clin Oncol 2012, 30:2670-2677.
    • (2012) J Clin Oncol , vol.30 , pp. 2670-2677
    • Kantarjian, H.M.1    Thomas, X.G.2    Dmoszynska, A.3    Wierzbowska, A.4    Mazur, G.5    Mayer, J.6
  • 5
    • 79952092841 scopus 로고    scopus 로고
    • Hypomethylating agents and other novel strategies in myelodysplastic syndromes
    • Garcia-Manero G., Fenaux P. Hypomethylating agents and other novel strategies in myelodysplastic syndromes. J Clin Oncol 2011, 29:516-523.
    • (2011) J Clin Oncol , vol.29 , pp. 516-523
    • Garcia-Manero, G.1    Fenaux, P.2
  • 6
    • 84892888839 scopus 로고    scopus 로고
    • Myelodysplastic syndromes: 2014 update on diagnosis, risk-stratification, and management
    • Garcia-Manero G. Myelodysplastic syndromes: 2014 update on diagnosis, risk-stratification, and management. Am J Hematol 2014, 89:97-108.
    • (2014) Am J Hematol , vol.89 , pp. 97-108
    • Garcia-Manero, G.1
  • 7
    • 0027941369 scopus 로고
    • Intensive postremission chemotherapy in adults with acute myeloid leukemia. Cancer and leukemia group B
    • Mayer R.J., Davis R.B., Schiffer C.A., Berg D.T., Powell B.L., Schulman P., et al. Intensive postremission chemotherapy in adults with acute myeloid leukemia. Cancer and leukemia group B. N Engl J Med 1994, 331:896-903.
    • (1994) N Engl J Med , vol.331 , pp. 896-903
    • Mayer, R.J.1    Davis, R.B.2    Schiffer, C.A.3    Berg, D.T.4    Powell, B.L.5    Schulman, P.6
  • 8
    • 84894030620 scopus 로고    scopus 로고
    • How we treat higher-risk myelodysplastic syndromes
    • Sekeres M.A., Cutler C. How we treat higher-risk myelodysplastic syndromes. Blood 2014, 123:829-836.
    • (2014) Blood , vol.123 , pp. 829-836
    • Sekeres, M.A.1    Cutler, C.2
  • 9
    • 77956862198 scopus 로고    scopus 로고
    • Outcome of patients with myelodysplastic syndrome after failure of decitabine therapy
    • Jabbour E., Garcia-Manero G., Batty N., Shan J., O'Brien S., Cortes J., et al. Outcome of patients with myelodysplastic syndrome after failure of decitabine therapy. Cancer 2010, 116:3830-3834.
    • (2010) Cancer , vol.116 , pp. 3830-3834
    • Jabbour, E.1    Garcia-Manero, G.2    Batty, N.3    Shan, J.4    O'Brien, S.5    Cortes, J.6
  • 10
    • 33750530675 scopus 로고    scopus 로고
    • Phase 1/2 study of the combination of 5-aza-2'-deoxycytidine with valproic acid in patients with leukemia
    • Garcia-Manero G., Kantarjian H.M., Sanchez-Gonzalez B., Yang H., Rosner G., Verstovsek S., et al. Phase 1/2 study of the combination of 5-aza-2'-deoxycytidine with valproic acid in patients with leukemia. Blood 2006, 108:3271-3279.
    • (2006) Blood , vol.108 , pp. 3271-3279
    • Garcia-Manero, G.1    Kantarjian, H.M.2    Sanchez-Gonzalez, B.3    Yang, H.4    Rosner, G.5    Verstovsek, S.6
  • 11
    • 34948845116 scopus 로고    scopus 로고
    • Safety and clinical activity of the combination of 5-azacytidine, valproic acid, and all-trans retinoic acid in acute myeloid leukemia and myelodysplastic syndrome
    • Soriano A.O., Yang H., Faderl S., Estrov Z., Giles F., Ravandi F., et al. Safety and clinical activity of the combination of 5-azacytidine, valproic acid, and all-trans retinoic acid in acute myeloid leukemia and myelodysplastic syndrome. Blood 2007, 110:2302-2308.
    • (2007) Blood , vol.110 , pp. 2302-2308
    • Soriano, A.O.1    Yang, H.2    Faderl, S.3    Estrov, Z.4    Giles, F.5    Ravandi, F.6
  • 12
    • 33846011361 scopus 로고    scopus 로고
    • Results of a randomized study of 3 schedules of low-dose decitabine in higher-risk myelodysplastic syndrome and chronic myelomonocytic leukemia
    • Kantarjian H., Oki Y., Garcia-Manero G., Huang X., O'Brien S., Cortes J., et al. Results of a randomized study of 3 schedules of low-dose decitabine in higher-risk myelodysplastic syndrome and chronic myelomonocytic leukemia. Blood 2007, 109:52-57.
    • (2007) Blood , vol.109 , pp. 52-57
    • Kantarjian, H.1    Oki, Y.2    Garcia-Manero, G.3    Huang, X.4    O'Brien, S.5    Cortes, J.6
  • 13
    • 33745968917 scopus 로고    scopus 로고
    • Clinical application and proposal for modification of the International Working Group (IWG) response criteria in myelodysplasia
    • Cheson B.D., Greenberg P.L., Bennett J.M., Lowenberg B., Wijermans P.W., Nimer S.D., et al. Clinical application and proposal for modification of the International Working Group (IWG) response criteria in myelodysplasia. Blood 2006, 108:419-425.
    • (2006) Blood , vol.108 , pp. 419-425
    • Cheson, B.D.1    Greenberg, P.L.2    Bennett, J.M.3    Lowenberg, B.4    Wijermans, P.W.5    Nimer, S.D.6
  • 14
  • 15
    • 33646051586 scopus 로고    scopus 로고
    • Superiority of prolonged low-dose azanucleoside administration? Results of 5-aza-2'-deoxycytidine retreatment in high-risk myelodysplasia patients
    • Ruter B., Wijermans P.W., Lubbert M. Superiority of prolonged low-dose azanucleoside administration? Results of 5-aza-2'-deoxycytidine retreatment in high-risk myelodysplasia patients. Cancer 2006, 106:1744-1750.
    • (2006) Cancer , vol.106 , pp. 1744-1750
    • Ruter, B.1    Wijermans, P.W.2    Lubbert, M.3
  • 16
    • 54049147814 scopus 로고    scopus 로고
    • Azacytidine causes complex DNA methylation responses in myeloid leukemia
    • Stresemann C., Bokelmann I., Mahlknecht U., Lyko F. Azacytidine causes complex DNA methylation responses in myeloid leukemia. Mol Cancer Ther 2008, 7:2998-3005.
    • (2008) Mol Cancer Ther , vol.7 , pp. 2998-3005
    • Stresemann, C.1    Bokelmann, I.2    Mahlknecht, U.3    Lyko, F.4
  • 17
    • 84875261536 scopus 로고    scopus 로고
    • Rapid loss of response after withdrawal of treatment with azacitidine: a case series in patients with higher-risk myelodysplastic syndromes or chronic myelomonocytic leukemia
    • Voso M.T., Breccia M., Lunghi M., Poloni A., Niscola P., Finelli C., et al. Rapid loss of response after withdrawal of treatment with azacitidine: a case series in patients with higher-risk myelodysplastic syndromes or chronic myelomonocytic leukemia. Eur J Haematol 2013, 90:345-348.
    • (2013) Eur J Haematol , vol.90 , pp. 345-348
    • Voso, M.T.1    Breccia, M.2    Lunghi, M.3    Poloni, A.4    Niscola, P.5    Finelli, C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.