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Volumn 90, Issue 4, 2013, Pages 345-348

Rapid loss of response after withdrawal of treatment with azacitidine: A case series in patients with higher-risk myelodysplastic syndromes or chronic myelomonocytic leukemia

Author keywords

Azacitidine; Chronic myelomonocytic leukemia; Hypomethylating agents; Myelodysplastic syndromes

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; AZACITIDINE;

EID: 84875261536     PISSN: 09024441     EISSN: 16000609     Source Type: Journal    
DOI: 10.1111/ejh.12079     Document Type: Article
Times cited : (36)

References (16)
  • 1
    • 62849104641 scopus 로고    scopus 로고
    • Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes: a randomised, open-label, phase III study
    • Fenaux P, Mufti GJ, Hellstrom-Lindberg E, et al. Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes: a randomised, open-label, phase III study. Lancet Oncol 2009;10:223-32.
    • (2009) Lancet Oncol , vol.10 , pp. 223-232
    • Fenaux, P.1    Mufti, G.J.2    Hellstrom-Lindberg, E.3
  • 2
    • 77957021267 scopus 로고    scopus 로고
    • Effects of azacitidine compared with conventional care regimens in elderly (≥ 75 years) patients with higher-risk myelodysplastic syndromes
    • Seymour JF, Fenaux P, Silverman LR, et al. Effects of azacitidine compared with conventional care regimens in elderly (≥ 75 years) patients with higher-risk myelodysplastic syndromes. Crit Rev Oncol Hematol 2010;76:218-27.
    • (2010) Crit Rev Oncol Hematol , vol.76 , pp. 218-227
    • Seymour, J.F.1    Fenaux, P.2    Silverman, L.R.3
  • 4
    • 84875266954 scopus 로고    scopus 로고
    • Vidaza Summary of Product Characteristics. Available at: (Accessed 4 October 2012)
    • Vidaza Summary of Product Characteristics. Available at: http://www.medicines.org.uk/EMC/medicine/21508/SPC/Vidaza%2025%20mg%20ml%20powder%20for%20suspension%20for%20injection/. (Accessed 4 October 2012)
  • 6
    • 33745968917 scopus 로고    scopus 로고
    • Clinical application and proposal for modification of the International Working Group (IWG) response criteria in myelodysplasia
    • Cheson BD, Greenberg PL, Bennett JM, et al. Clinical application and proposal for modification of the International Working Group (IWG) response criteria in myelodysplasia. Blood 2006;108(2):419-25.
    • (2006) Blood , vol.108 , Issue.2 , pp. 419-425
    • Cheson, B.D.1    Greenberg, P.L.2    Bennett, J.M.3
  • 7
    • 79952346792 scopus 로고    scopus 로고
    • Risk stratification based on both disease status and extra-hematologic comorbidities in patients with myelodysplastic syndrome
    • Della PM, Malcovati L, Strupp C, et al. Risk stratification based on both disease status and extra-hematologic comorbidities in patients with myelodysplastic syndrome. Haematologica 2011;96:441-9.
    • (2011) Haematologica , vol.96 , pp. 441-449
    • Della, P.M.1    Malcovati, L.2    Strupp, C.3
  • 8
    • 79956294708 scopus 로고    scopus 로고
    • de WT, Wijermans PW. Low-dose decitabine versus best supportive care in elderly patients with intermediate- or high-risk myelodysplastic syndrome (MDS) ineligible for intensive chemotherapy: final results of the randomized phase III study of the European Organisation for Research and Treatment of Cancer Leukemia Group and the German MDS Study Group
    • Lubbert M, Suciu S, Baila L, et al. de WT, Wijermans PW. Low-dose decitabine versus best supportive care in elderly patients with intermediate- or high-risk myelodysplastic syndrome (MDS) ineligible for intensive chemotherapy: final results of the randomized phase III study of the European Organisation for Research and Treatment of Cancer Leukemia Group and the German MDS Study Group. J Clin Oncol 2011;29:1987-96.
    • (2011) J Clin Oncol , vol.29 , pp. 1987-1996
    • Lubbert, M.1    Suciu, S.2    Baila, L.3
  • 9
    • 54049147814 scopus 로고    scopus 로고
    • Azacytidine causes complex DNA methylation responses in myeloid leukemia
    • Stresemann C, Bokelmann I, Mahlknecht U, Lyko F. Azacytidine causes complex DNA methylation responses in myeloid leukemia. Mol Cancer Ther 2008;7:2998-3005.
    • (2008) Mol Cancer Ther , vol.7 , pp. 2998-3005
    • Stresemann, C.1    Bokelmann, I.2    Mahlknecht, U.3    Lyko, F.4
  • 10
    • 33646051586 scopus 로고    scopus 로고
    • Superiority of prolonged low-dose azanucleoside administration? Results of 5-aza-2′-deoxycytidine retreatment in high-risk myelodysplasia patients
    • Ruter B, Wijermans PW, Lubbert M. Superiority of prolonged low-dose azanucleoside administration? Results of 5-aza-2′-deoxycytidine retreatment in high-risk myelodysplasia patients. Cancer 2006;106:1744-50.
    • (2006) Cancer , vol.106 , pp. 1744-1750
    • Ruter, B.1    Wijermans, P.W.2    Lubbert, M.3
  • 11
    • 80051992418 scopus 로고    scopus 로고
    • Outcome of high-risk myelodysplastic syndrome after azacitidine treatment failure
    • Prebet T, Gore SD, Esterni B, et al. Outcome of high-risk myelodysplastic syndrome after azacitidine treatment failure. J Clin Oncol 2011;29:3322-7.
    • (2011) J Clin Oncol , vol.29 , pp. 3322-3327
    • Prebet, T.1    Gore, S.D.2    Esterni, B.3
  • 14
    • 78650172030 scopus 로고    scopus 로고
    • de BS, Chelghoum Y, Taksin AL, Plantier I, Ame S, Boehrer S, Gardin C, Beach CL, Ades L, Fenaux P. Prognostic factors for response and overall survival in 282 patients with higher-risk myelodysplastic syndromes treated with azacitidine
    • Itzykson R, Thepot S, Quesnel B, et al. de BS, Chelghoum Y, Taksin AL, Plantier I, Ame S, Boehrer S, Gardin C, Beach CL, Ades L, Fenaux P. Prognostic factors for response and overall survival in 282 patients with higher-risk myelodysplastic syndromes treated with azacitidine. Blood 2011;117:403-11.
    • (2011) Blood , vol.117 , pp. 403-411
    • Itzykson, R.1    Thepot, S.2    Quesnel, B.3
  • 15
    • 77954753267 scopus 로고    scopus 로고
    • Gore S D, Seymour JF, Backstrom J, Beach CL. Management and supportive care measures for adverse events in patients with myelodysplastic syndromes treated with azacitidine
    • Santini V, Fenaux P, Mufti GJ, Hellstrom-Lindberg E, Silverman LR, List A. Gore S D, Seymour JF, Backstrom J, Beach CL. Management and supportive care measures for adverse events in patients with myelodysplastic syndromes treated with azacitidine. Eur J Haematol 2010;85:130-8.
    • (2010) Eur J Haematol , vol.85 , pp. 130-138
    • Santini, V.1    Fenaux, P.2    Mufti, G.J.3    Hellstrom-Lindberg, E.4    Silverman, L.R.5    List, A.6
  • 16
    • 79959586108 scopus 로고    scopus 로고
    • Perceptions of disease state, treatment outcomes, and prognosis among patients with myelodysplastic syndromes: results from an internet-based survey
    • Sekeres MA, Maciejewski JP, List AF, Steensma DP, Artz A, Swern AS, Scribner P, Huber J, Stone R. Perceptions of disease state, treatment outcomes, and prognosis among patients with myelodysplastic syndromes: results from an internet-based survey. Oncologist 2011;16:904-11.
    • (2011) Oncologist , vol.16 , pp. 904-911
    • Sekeres, M.A.1    Maciejewski, J.P.2    List, A.F.3    Steensma, D.P.4    Artz, A.5    Swern, A.S.6    Scribner, P.7    Huber, J.8    Stone, R.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.