Targeted deletion of collagen V in tendons and ligaments results in a classic Ehlers-Danlos syndrome joint phenotype

American Journal of Pathology

Volumn 185, Issue 5, 2015, Pages 1436-1447

  Sun, Mei ^a   Connizzo, Brianne K ^b   Adams, Sheila M ^a   Freedman, Benjamin R ^b   Wenstrup, Richard J ^c   Soslowsky, Louis J ^b   Birk, David E ^a  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c Utah   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN TYPE 5;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTERIOR CRUCIATE LIGAMENT; ARTICLE; BODY SIZE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; EHLERS DANLOS SYNDROME; EXON; GAIT; GAIT DISORDER; GENE DELETION; GENE EXPRESSION; GENE TARGETING; GRIP STRENGTH; HAND GRIP; JOINT LAXITY; KNOCKOUT MOUSE; LIGAMENT; MALE; MOUSE; MOUSE MODEL; NONHUMAN; OSTEOARTHRITIS; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN STRUCTURE; RIGIDITY; TENDON; TISSUE SPECIFICITY; YOUNG MODULUS; ANIMAL; BIOMECHANICS; DEFICIENCY; DISEASE MODEL; HAND STRENGTH; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; JOINT; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; TRANSMISSION ELECTRON MICROSCOPY;

ANIMALS; BIOMECHANICAL PHENOMENA; COLLAGEN TYPE V; DISEASE MODELS, ANIMAL; EHLERS-DANLOS SYNDROME; GAIT; HAND STRENGTH; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; JOINTS; LIGAMENTS; MICE; MICE, KNOCKOUT; MICROSCOPY, ELECTRON, TRANSMISSION; PHENOTYPE; REAL-TIME POLYMERASE CHAIN REACTION; TENDONS;

EID: 84928041930     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2015.01.031     Document Type: Article

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