Loss of FOXA1 drives sexually dimorphic changes in urothelial differentiation and is an independent predictor of poor prognosis in bladder cancer

American Journal of Pathology

Volumn 185, Issue 5, 2015, Pages 1385-1395

  Reddy, Opal L ^a   Cates, Justin M ^b   Gellert, Lan L ^b   Crist, Henry S ^c   Yang, Zhaohai ^c   Yamashita, Hironobu ^c   Taylor, John A ^d   Smith, Joseph A ^b   Chang, Sam S ^b   Cookson, Michael S ^e   You, Chaochen ^b   Barocas, Daniel A ^b   Grabowska, Magdalena M ^b   Ye, Fei ^f   Wu, Xue Ru ^g   Yi, Yajun ^f   Matusik, Robert J ^b   Kaestner, Klaus H ^h   Clark, Peter E ^b   Degraff, David J ^c,i  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^c PENN STATE COLLEGE OF MEDICINE   (United States)

^d UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

^e UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

^f VANDERBILT UNIVERSITY   (United States)

^g NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^h UNIVERSITY OF PENNSYLVANIA   (United States)

ⁱ PENN STATE MILTON S HERSHEY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKERATIN 14; HEPATOCYTE NUCLEAR FACTOR 3ALPHA; RNA; TAMOXIFEN; FOXA1 PROTEIN, HUMAN; TRANSCRIPTOME; TUMOR MARKER;

ADULT; AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLADDER CANCER; CANCER ADJUVANT THERAPY; CANCER PROGNOSIS; CANCER SURVIVAL; CELL DIFFERENTIATION; CONTROLLED STUDY; FEMALE; FOLLOW UP; GENE EXPRESSION; GENE LOSS; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; KERATINOCYTE; KNOCKOUT MOUSE; MAJOR CLINICAL STUDY; MALE; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; OVERALL SURVIVAL; PRIORITY JOURNAL; RNA EXTRACTION; SEX DIFFERENCE; TISSUE DIFFERENTIATION; UROTHELIUM; ANIMAL; BLADDER TUMOR; DISEASE MODEL; DNA MICROARRAY; KAPLAN MEIER METHOD; METABOLISM; MIDDLE AGED; MORTALITY; PATHOLOGY; PHYSIOLOGY; PROGNOSIS; PROPORTIONAL HAZARDS MODEL; SEXUAL DEVELOPMENT; TISSUE MICROARRAY; TRANSITIONAL CELL CARCINOMA;

AGED; ANIMALS; BIOMARKERS, TUMOR; CARCINOMA, TRANSITIONAL CELL; CELL DIFFERENTIATION; DISEASE MODELS, ANIMAL; FEMALE; HEPATOCYTE NUCLEAR FACTOR 3-ALPHA; HUMANS; IMMUNOHISTOCHEMISTRY; KAPLAN-MEIER ESTIMATE; KERATIN-14; MALE; MICE; MICE, KNOCKOUT; MIDDLE AGED; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; SEX CHARACTERISTICS; TISSUE ARRAY ANALYSIS; TRANSCRIPTOME; URINARY BLADDER NEOPLASMS; UROTHELIUM;

EID: 84928041218     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2015.01.014     Document Type: Article

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