Disability and co-morbidity in relation to frailty: How much do they overlap?

Archives of Gerontology and Geriatrics

Volumn 55, Issue 2, 2012, Pages e1-

  Theou, Olga ^a   Rockwood, Michael R H ^a   Mitnitski, Arnold ^a   Rockwood, Kenneth ^a  

^a DALHOUSIE UNIVERSITY   (Canada)

Author keywords

Aging; Co morbidity; Disability; Frail

Indexed keywords

ADL DISABILITY; AGED; ARTICLE; COHORT ANALYSIS; COMORBIDITY; CONTROLLED STUDY; DAILY LIFE ACTIVITY; DISABILITY; FEMALE; FRAIL ELDERLY; FUNCTIONAL ASSESSMENT; HAZARD RATIO; HUMAN; MAJOR CLINICAL STUDY; MALE; MORBIDITY; MORTALITY; POPULATION RESEARCH; PREDICTION; PRIORITY JOURNAL; RISK FACTOR; SCORING SYSTEM;

EID: 84864939826     PISSN: 01674943     EISSN: 18726976     Source Type: Journal    
DOI: 10.1016/j.archger.2012.03.001     Document Type: Article

References (58)

1. Abellan van Kan G., Rolland Y., Bergman H., Morley J.E., Kritchevsky S.B., Vellas B. The I.A.N.A. Task Force on frailty assessment of older people in clinical practice. J. Nutr. Health Aging 2008, 12:29-37.
2. Abellan van Kan G., Rolland Y., Houles M., Gillette-Guyonnet S., Soto M., Vellas B. The assessment of frailty in older adults. Clin. Geriatr. Med. 2010, 26:275-286.
3. Al Snih S., Graham J.E., Ray L.A., Samper-Ternent R., Markides K.S., Ottenbacher K.J. Frailty and incidence of activities of daily living disability among older Mexican Americans. J. Rehabil. Med. 2009, 41:892-897.
4. Bandeen-Roche K., Xue Q.L., Ferrucci L., Walston J., Guralnik J.M., Chaves P., Zeger S.L., Fried L.P. Phenotype of frailty: characterization in the women's health and aging studies. J. Gerontol. A. Biol. Sci. Med. Sci. 2006, 61:262-266.
5. Bergman H., Béland F., Karunanathan S., Hummel S., Hogan D., Wolfson C. Developing a working framework for understanding frailty. Gérontol. Soc. 2004, 109:15-29.
6. Clegg A., Young J. The frailty syndrome. Clin. Med. 2011, 11:72-75.
7. Crews D.E., Zavotka S. Aging, disability, and frailty: implications for universal design. J. Physiol. Anthropol. 2006, 25:113-118.
8. Canadian Study of Health Aging Working Group Disability and frailty among elderly Canadians: a comparison of six surveys. Int. Psychogeriatr. 2001, 13(Suppl. 1):159-167.
9. Canadian Study of Health Aging Working Group Canadian study of health and aging: study methods and prevalence of dementia. Can. Med. Assoc. J. 1994, 150:899-913.
10. Davis D.H., Rockwood M.R., Mitnitski A.B., Rockwood K. Impairments in mobility and balance in relation to frailty. Arch. Gerontol. Geriatr. 2011, 53:79-83.
11. Eckel S.P., Bandeen-Roche K., Chaves P.H., Fried L.P., Louis T.A. Surrogate screening models for the low physical activity criterion of frailty. Aging Clin. Exp. Res. 2011, 23:209-216.
12. Ensrud K.E., Ewing S.K., Cawthon P.M., Fink H.A., Taylor B.C., Cauley J.A., Dam T.T., Marshall L.M., Orwoll E.S., Cummings S.R. A comparison of frailty indexes for the prediction of falls, disability, fractures, and mortality in older men. J. Am. Geriatr. Soc. 2009, 57:492-498. Osteoporotic Fractures in Men Research Group.
13. Fieo R.A., Austin E.J., Starr J.M., Deary I.J. Calibrating ADL-IADL scales to improve measurement accuracy and to extend the disability construct into the preclinical range: a systematic review. BMC Geriatr. 2011, 11:42.
14. Fried L.P., Tangen C.M., Walston J., Newman A.B., Hirsch C., Gottdiener J., Seeman T., Tracy R., Kop W.J., Burke G., McBurnie M.A. Frailty in older adults: evidence for a phenotype. J. Gerontol. A. Biol. Sci. Med. Sci. 2001, 56:M146-M156. Cardiovascular Health Study Collaborative Research Group.
15. Fried L.P., Ferrucci L., Darer J., Williamson J.D., Anderson G. Untangling the concepts of disability, frailty, and comorbidity: Implications for improved targeting and care. J. Gerontol. A. Biol. Sci. Med. Sci. 2004, 59:255-263.
16. Gill T.M., Guo Z., Allore H.G. The epidemiology of bathing disability in older persons. J. Am. Geriatr. Soc. 2006, 54:1524-1530.
17. Graf C. The Lawton instrumental activities of daily living scale. Am. J. Nurs. 2008, 108:52-62.
18. Guralnik J.M., Ferrucci L., Simonsick E.M., Salive M.E., Wallace R.B. Lower-extremity function in persons over the age of 70 years as a predictor of subsequent disability. N. Engl. J. Med. 1995, 339:556-561.
19. Hubbard R.E., O'Mahony M.S., Woodhouse K.W. Characterising frailty in the clinical setting - a comparison of different approaches. Age Ageing 2009, 38:115-119.
20. Hubbard R.E., O'Mahony M.S., Savva G.M., Calver B.L., Woodhouse K.W. Inflammation and frailty measures in older people. J. Cell. Mol. Med. 2009, 13:3103-3109.
21. Hybels C.F., Pieper C.F., Blazer D.G., Fillenbaum G.G., Steffens D.C. Trajectories of mobility and IADL function in older patients diagnosed with major depression. Int. J. Geriatr. Psychiatry 2010, 25:74-81.
22. Imuta H., Yasumura S., Abe H., Fukao A. The prevalence and psychosocial characteristics of the frail elderly in Japan: a community-based study. Aging (Milano) 2001, 13:443-453.
23. Inouye S.K., Studenski S., Tinetti M.E., Kuchel G.A. Geriatric syndromes: clinical, research, and policy implications of a core geriatric concept. J. Am. Geriatr. Soc. 2007, 55:780-791.
24. Jones D., Song X., Mitnitski A., Rockwood K. Evaluation of a frailty index based on a comprehensive geriatric assessment in a population based study of elderly Canadians. Aging Clin. Exp. Res. 2005, 17:465-471.
25. Katz S., Down T.D., Cash H.R., Grotz R. Progress in the development of the index of ADL. Gerontologist 1970, 10:20-30.
26. Kulminski A.M., Yashin A.I., Ukraintseva S.V., Akushevich I., Arbeev K.G., Land K., Manton K. Accumulation of health disorders as a systemic measure of aging: findings from the NLTCS data. Mech. Ageing Dev. 2006, 127:840-848.
27. Kulminski A.M., Ukraintseva S.V., Kulminskaya I.V., Arbeev K.G., Land K., Yashin A.I. Cumulative deficits better characterize susceptibility to death in elderly people than phenotypic frailty: lessons from the Cardiovascular Health Study. J. Am. Geriatr. Soc. 2008, 56:898-903.
28. Lawton M.P., Brody E.M. Assessment of older people self-maintaining and instrumental activities of daily living. Gerontologist 1969, 9:179-186.
29. Levers M.-J., Estabrooks C.A., Ross Kerr J.C. Factors contributing to frailty: literature review. J. Adv. Nurs. 2006, 56:282-291.
30. Markle-Reid M., Browne G. Conceptualization of frailty in relation to older adults. J. Adv. Nurs. 2003, 44:58-68.
31. Martin F.C., Brighton P. Frailty: different tools for different purposes?. Age Ageing 2008, 37:129-131.
32. Mitnitski A., Mogilner A., Rockwood K. Accumulation of deficits as a proxy measure of aging. ScientificWorldJournal 2001, 1:323-336.
33. Mitnitski A., Song X., Skoog I., Broe G.A., Cox J.L., Grunfeld E., Rockwood K. Relative fitness and frailty of elderly men and women in developed countries and their relationship with mortality. J. Am. Geriatr. Soc. 2005, 53:2184-2189.
34. Mitnitski A., Fallah N., Rockwood M.R.H., Rockwood K. Transitions in cognitive status in relation to frailty in older adults: a comparison of three frailty measures. J. Nutr. Health Aging 2011, 15:863-867.
35. Nourhashémi F., Andrieu S., Gillette-Guyonnet S., Vellas B., Albarède J.L., Grandjean H. Instrumental activities of daily living as a potential marker of frailty: a study of 7364 community-dwelling elderly women (the EPIDOS study). J. Gerontol. A. Biol. Sci. Med. Sci. 2001, 56:M448-M453.
36. Public Health Agency of Canada National Advisory Council on Aging: Seniors in Canada 2006 Report Card (Catalogue No. HP30-1/2006E). Ottawa, Ontario 2006.
37. Puts M.T., Lips P., Deeg D.J. Static and dynamic measures of frailty predicted decline in performance-based and self-reported physical functioning. J. Clin. Epidemiol. 2005, 58:1188-1198.
38. Rimmer J.H. Exercise and physical activity in persons aging with a physical disability. Phys. Med. Rehabil. Clin. N. Am. 2005, 16:41-56.
39. Robinson T.N., Eiseman B., Wallace J.I., Church S.D., McFann K.K., Pfister S.M., Sharp T.J., Moss M. Redefining geriatric preoperative assessment using frailty, disability and co-morbidity. Ann. Surg. 2009, 250:449-455.
40. Rockwood K., Mitnitski A. Limits to deficit accumulation in elderly people. Mech. Ageing Dev. 2006, 127:494-496.
41. Rockwood K., Mitnitski A. Frailty defined by deficit accumulation and geriatric medicine defined by frailty. Clin. Geriatr. Med. 2011, 27:17-26.
42. Rockwood K., Fox R.A., Stolee P., Robertson D., Beattie B.L. Frailty in elderly people: an evolving concept. Can. Med. Assoc. J. 1994, 150:489-495.
43. Rockwood K., Hogan D.B., MacKnight C. Conceptualisation and measurement of frailty in elderly people. Drugs Aging 2000, 17:295-302.
44. Rockwood K., Andrew M., Mitnitski A. A comparison of two approaches to measuring frailty in elderly people. J. Gerontol. A. Biol. Sci. Med. Sci. 2007, 62A:738-743.
45. Rockwood K., Rockwood M.R., Mitnitski A. Physiological redundancy in older adults in relation to the change with age in the slope of a frailty index. J. Am. Geriatr. Soc. 2010, 58:318-323.
46. Rockwood K., Song X., Mitnitski A. Changes in relative fitness and frailty across the adult lifespan: evidence from the Canadian National Population Health Survey. Can. Med. Assoc. J. 2011, 183:E487-E494.
47. Roth E.J., Lovell L. Community skill performance and its association with the ability to perform everyday tasks by stroke survivors one year following rehabilitation discharge. Top Stroke Rehabil. 2007, 14:48-56.
48. Searle S.D., Mitnitski A., Gahbauer E.A., Gill T.M., Rockwood K. A standard procedure for creating a frailty index in a cohort study. BMC Geriatr. 2008, 8:24.
49. Teng E.L., Chui H.C. The Modified Mini-Mental State (3MS) examination. J. Clin. Psychiatry 1987, 48:314-318.
50. Terry D.F., Sebastiani P., Andersen S.L., Perls T.T. Disentangling the roles of disability and morbidity in survival to exceptional old age. Arch. Intern. Med. 2008, 168:277-283.
51. Theou O., Kloseck M. Tools to identify community-dwelling older adults in different stages of frailty. Phys. Occup. Ther. Geriatr. 2007, 26:1-21.
52. Theou, O., Rockwood, K. Should frailty status always be considered when treating the elderly patient? Aging Health, in press.
53. Theou O., Stathokostas L., Roland K., Jakobi J., Patterson C., Vandervoort A., Jones G.R. The effectiveness of exercise interventions for the management of frailty: a systematic review. J. Aging Res. 2011, 2011:1-19.
54. Thomas V.S., Rockwood K., McDowell I. Multidimensionality in instrumental and basic activities of daily living. J. Clin. Epidemiol. 1998, 51:315-321.
55. Topinkova E. Aging disability and frailty. Ann. Nutr. Metab. 2008, 52(Suppl. 1):6-11.
56. Vermeulen J., Neyens J.C., van Rossum E., Spreeuwenberg M.D., de Witte L.P. Predicting ADL disability in community-dwelling elderly people using physical frailty indicators: a systematic review. BMC Geriatr. 2011, 11:33.
57. Wolff J.L., Starfield B., Anderson G. Prevalence, expenditures, and complications of multiple chronic conditions in the elderly. Arch. Intern. Med. 2002, 162:2269-2276.
58. Wong C.H., Weiss D., Sourial N., Karunananthan S., Quail J.M., Wolfson C., Bergman H. Frailty and its association with disability and comorbidity in a community-dwelling sample of seniors in Montreal: a cross-sectional study. Aging Clin. Exp. Res. 2010, 22:54-62.