High-speed intravascular photoacoustic imaging of lipid-laden atherosclerotic plaque enabled by a 2-kHz Barium Nitrite Raman Laser

Scientific Reports

Volumn 4, Issue , 2014, Pages

  Wang, Pu ^a   Ma, Teng ^a   Slipchenko, Mikhail N ^a,c   Liang, Shanshan ^d,e,f   Hui, Jie ^g   Shung, K Kirk ^b   Roy, Sukesh ^c   Sturek, Michael ^h   Zhou, Qifa ^b   Chen, Zhongping ^d   Cheng, Ji Xin ^a  

^a PURDUE UNIVERSITY   (United States)

^b University of Southern California ^*  (United States)

^c 5100 Springfield St Suite 301   (United States)

^d University of California at Irvine   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f UNIVERSITY OF CALIFORNIA   (United States)

^g PURDUE UNIVERSITY   (United States)

^h INDIANA UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LIPID;

ANIMAL; ATHEROSCLEROTIC PLAQUE; DEVICES; DIAGNOSTIC IMAGING; ILIAC ARTERY; IMAGE QUALITY; LASER; MINIPIG; PATHOLOGY; PHOTOACOUSTICS; PIG;

ANIMALS; DIAGNOSTIC IMAGING; ILIAC ARTERY; LASERS; LIPIDS; PHANTOMS, IMAGING; PHOTOACOUSTIC TECHNIQUES; PLAQUE, ATHEROSCLEROTIC; SWINE; SWINE, MINIATURE;

EID: 84928028689     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep06889     Document Type: Article

References (36)

1. Writing group members et al. Heart disease and stroke statistics-2009 update: A report from the american heart association statistics committee and stroke statistics subcommittee. Circulation 119, e21-181; DOI:10.1161/circulationaha.108.191261 (2009).
2. Naghavi, M. et al. From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies: part I. Circulation 108, 1664-1672; DOI:10.1161/01.cir.0000087480.94275.97 (2003).
3. Libby, P. Inflammation in atherosclerosis. Nature 420, 868-874 (2002).
4. Buja, L. M. & Willerson, J. T. Role of inflammation in coronary plaque disruption. Circulation 89, 503-505; DOI:10.1161/01.cir.89.1.503 (1994).
5. Libby, P., DiCarli, M. & Weissleder, R. The Vascular Biology of Atherosclerosis and Imaging Targets. J. Nucl. Med. 51, 33S-37S; DOI:10.2967/jnumed.109.069633 (2010).
6. Puri, R., Tuzcu, E. M., Nissen, S. E. & Nicholls, S. J. Exploring coronary atherosclerosis with intravascular imaging. Int. J. Cardiol. 168, 670-679; DOI:10.1016/j.ijcard.2013.03.024 (2013).
7. Falk, E. & Wilensky, R. L. Prediction of Coronary Events by Intravascular Imaging. J Am Coll Cardiol Img. 5, S38-S41; DOI:10.1016/j.jcmg.2012.01.007 (2012).
8. Virmani, R., Burke, A. P., Farb, A. & Kolodgie, F. D. Pathology of the Vulnerable Plaque. J. Am. Coll. Cardiol. 47, C13-C18; DOI:10.1016/j.jacc.2005.10.065 (2006).
9. Choudhury, R. P., Fuster, V. & Fayad, Z. A. Molecular, cellular and functional imaging of atherothrombosis. Nat Rev Drug Discov 3, 913-925 (2004).
10. Thim, T. et al. Unreliable Assessment of Necrotic Core by Virtual Histology Intravascular Ultrasound in Porcine Coronary Artery Disease. Circ Cardiovasc Imaging 3, 384-391; DOI:10.1161/circimaging.109.919357 (2010).
11. Moreno, P. R. et al. Detection of lipid pool, thin fibrous cap, and Inflammatory cells in human aortic atherosclerotic plaques by near-infrared spectroscopy. Circulation 105, 923-927; DOI:10.1161/hc0802.104291 (2002).
12. Caplan, J. D., Waxman, S., Nesto, R. W. & Muller, J. E. Near-infrared spectroscopy for the detection of vulnerable coronary artery plaques. J. Am. Coll. Cardiol. 47, C92-C96 (2006).
13. Brugaletta, S. et al. NIRS and IVUS for characterization of atherosclerosis in patients undergoing coronary angiography. J Am Coll Cardiol Img. 4, 647-655; DOI:10.1016/j.jcmg.2011.03.013 (2011).
14. Liang, S. et al. Intravascular atherosclerotic imaging with combined fluorescence and optical coherence tomography probe based on a double-clad fiber combiner. J. Biomed. Opt. 17, 070501; DOI:10.1117/1.JBO.17.7.070501 (2012).
15. Yoo, H. et al. Intra-arterial catheter for simultaneous microstructural and molecular imaging in vivo. Nat. Methods 17, 1680-1684; DOI:10.1038/nm.2555 (2011).
16. Yin, J. et al. Novel combined miniature optical coherence tomography ultrasound probe for in vivo intravascular imaging. J. Biomed. Opt. 16, 060505; DOI:10.1117/1.3589097 (2011).
17. Li, J. et al. Miniature optical coherence tomography-ultrasound probe for automatically coregistered three-dimensional intracoronary imaging with realtime display. J. Biomed. Opt. 18, 100502; DOI:10.1117/1.JBO.18.10.100502 (2013).
18. Li, J. et al. Integrated IVUS-OCT for Real-Time Imaging of Coronary Atherosclerosis. J Am Coll Cardiol Img. 7, 101-103; DOI:10.1016/j.jcmg.2013.07.012 (2014).
19. Yang, J.-M. et al. Simultaneous functional photoacoustic and ultrasonic endoscopy of internal organs in vivo. Nat. Methods 18, 1297-1302; DOI:10.1038/nm.2823 (2012).
20. Li, X., Wei, W., Zhou, Q., Shung, K. K. & Chen, Z. Intravascular photoacoustic imaging at 35 and 80 MHz. J. Biomed. Opt. 17, 106005; DOI:10.1117/1.JBO.17.10.106005 (2012).
21. Wang, H.-W. et al. Label-free bond-selective imaging by listening to vibrationally excited molecules. Phys. Rev. Lett. 106, 238106 (2011).
22. Jansen, K., van der Steen, A. F. W., van Beusekom, H. M. M., Oosterhuis, J. W. & van Soest, G. Intravascular photoacoustic imaging of human coronary atherosclerosis. Opt. Lett. 36, 597-599 (2011).
23. Wang, B. et al. Intravascular photoacoustic imaging of lipid in atherosclerotic plaques in the presence of luminal blood. Opt. Lett. 37, 1244-1246 (2012).
24. Wang, P., Rajian, J. R. & Cheng, J.-X. Spectroscopic Imaging of Deep Tissue through Photoacoustic Detection of Molecular Vibration. J. Phys. Chem. Lett. 4, 2177-2185; DOI:10.1021/jz400559a (2013).
25. Wang, P., Wang, H.-W., Sturek, M. &Cheng, J.-X. Bond-selective imagingofdeep tissue through the optical window between 1600 and 1850 nm. J. Biophotonics 5, 25-32; DOI:10.1002/jbio.201100102 (2012).
26. Bai, X. et al. Intravascular Optical-Resolution Photoacoustic Tomography with a 1.1 mm Diameter Catheter. PLOS ONE 9, e92463; DOI:10.1371/journal.pone.0092463 (2014).
27. Li, R., Slipchenko, M. N., Wang, P. & Cheng, J. X. Compact high power barium nitrite crystal-based Raman laser at 1197 nm for photoacoustic imaging of fat. J. Biomed. Opt. 18, 040502; DOI:10.1117/1.JBO.18.4.040502 (2013).
28. Rajian, J. R., Li, R., Wang, P. & Cheng, J.-X. Vibrational Photoacoustic Tomography: Chemical Imaging beyond the Ballistic Regime. J. Phys. Chem. Lett. 4, 3211-3215; DOI:10.1021/jz401638e (2013).
29. Laser Institute of America, in American National Standard for Safe Use of Lasers in Research, Development, or Testing ANSI Z136.8-2012 (American National Standards Institute, Inc., 2012).
30. Mintz, G. S. et al. American College of Cardiology clinical expert consensus document on standards for acquisition, measurement and reporting of intravascular ultrasound studies (ivus)33A report of the american college of cardiology task force on clinical expert consensus documents developed in collaboration with the european society of cardiology endorsed by the society of cardiac angiography and interventions. J. Am. Coll. Cardiol. 37, 1478-1492; DOI:10.1016/S0735-1097(01)01175-5 (2001).
31. Jansen, K. et al. Spectroscopic intravascular photoacoustic imaging of lipids in atherosclerosis. J. Biomed. Opt. 19, 026006; DOI:10.1117/1.JBO.19.2.026006 (2014).
32. Wang, P., Wang, P., Wang, H. W. & Cheng, J. X. Mapping lipid and collagen by multispectral photoacoustic imaging of chemical bond vibration. J. Biomed. Opt. 17, 96010-96011; DOI:10.1117/1.JBO.17.9.096010 (2012).
33. Al-Masoodi, A. H.H. et al. Q-switched Yb-doped fiber laser operating at 1073 nm using a carbon nanotubes saturable absorber. Microw. Opt. Technol. Lett. 56, 1770-1773; DOI:10.1002/mop.28447 (2014).
34. Radu, M. D. & Falk, E. In search of vulnerable features of coronary plaques with optical coherence tomography: is it time to rethink the current methodological concepts? Eur. Heart J. 33, 9-12; DOI:10.1093/eurheartj/ehr290 (2012).
35. Ma, T. et al. Systematic study of high-frequency ultrasonic transducer design for laser-scanning photoacoustic ophthalmoscopy. J. Biomed. Opt. 19, 16015; DOI:10.1117/1.JBO.19.1.016015 (2014).
36. Sturek, M. et al. Swine in the Laboratory: Surgery, Anesthesia, Imaging, and Experimental Techniques [Swindle, M. Michael (ed.)] [398-399] (Boca Raton, FL, 2007).