Tumor-environment biomimetics delay peritoneal metastasis formation by deceiving and redirecting disseminated cancer cells

Biomaterials

Volumn 54, Issue , 2015, Pages 148-157

  De Vlieghere, Elly ^a   Gremonprez, Félix ^b   Verset, Laurine ^c   Mariën, Lore ^a   Jones, Christopher J ^d   De Craene, Bram ^a,e   Berx, Geert ^a,e   Descamps, Benedicte ^a   Vanhove, Christian ^a   Remon, Jean Paul ^a   Ceelen, Wim ^b   Demetter, Pieter ^c   Bracke, Marc ^a   De Geest, Bruno G ^a   De Wever, Olivier ^a  

^a GHENT UNIVERSITY   (Belgium)

^b GHENT UNIVERSITY HOSPITAL   (Belgium)

^c ERASME HOSPITAL   (Belgium)

^d CARDIFF UNIVERSITY   (United Kingdom)

^e DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

Author keywords

Biomimetic trap; Cancer associated fibroblasts; Cell adhesion; Microencapsulation; Peritoneal metastasis; Tumor environment

Indexed keywords

BIOMIMETICS; CELL ADHESION; CELL CULTURE; COATINGS; FIBROBLASTS; MICROENCAPSULATION; PATHOLOGY; POLYELECTROLYTES; PROTEINS; ROOM AND PILLAR MINING; TUMORS;

ABDOMINAL CAVITY; BIODEGRADABLE COATINGS; EXTRACELLULAR MATRIX PROTEIN; INFLAMMATORY REACTION; MESOTHELIAL CELLS; PERITONEAL CAVITY; PERITONEAL METASTASIS; POLYELECTROLYTE COATINGS;

DISEASES;

ALGINIC ACID; BIOMATERIAL; GELATIN; POLY(ALLYLAMINE HYDROCHLORIDE); POLY(STYRENE SULFONATE); POLYELECTROLYTE; POLYMER; SCLEROPROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOMIMETICS; CANCER ASSOCIATED FIBROBLAST; CANCER CELL; CANCER PREVENTION; CELL ADHESION; CELL ENCAPSULATION; CELL SURFACE; CELL VIABILITY; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DISSEMINATED CANCER; EXTRACELLULAR MATRIX; EXTRACELLULAR TRAP; FEMALE; FIBROBLAST; HUMAN; HUMAN CELL; HUMAN TISSUE; MEMBRANE MICROPARTICLE; METASTASIS INHIBITION; MOUSE; NONHUMAN; PARTICLE SIZE; PERITONEAL CAVITY; PERITONEUM METASTASIS; PRIORITY JOURNAL; SURGICAL WOUND; SURVIVAL RATE; TUMOR MICROENVIRONMENT; ANIMAL; CELL COMMUNICATION; EXPERIMENTAL NEOPLASM; NUDE MOUSE; PATHOLOGY; PERITONEAL NEOPLASMS; PROCEDURES; SECONDARY; TUMOR CELL LINE; TUMOR EMBOLISM;

ANIMALIA;

ANIMALS; BIOMIMETICS; CELL COMMUNICATION; CELL LINE, TUMOR; FEMALE; MICE; MICE, NUDE; NEOPLASMS, EXPERIMENTAL; NEOPLASTIC CELLS, CIRCULATING; PERITONEAL NEOPLASMS; TUMOR MICROENVIRONMENT;

EID: 84928015634     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2015.03.012     Document Type: Article

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