ADP-ribose/TRPM2-mediated Ca 2+ signaling is essential for cytolytic degranulation and antitumor activity of natural killer cells

Scientific Reports

Volumn 5, Issue , 2015, Pages

  Rah, So Young ^a   Kwak, Jae Yong ^a   Chung, Yun Jo ^a   Kim, Uh Hyun ^a  

^a Chonbuk National University Medical School   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DIPHOSPHATE RIBOSE; CALCIUM; CD38 ANTIGEN; CYCLIC AMP DEPENDENT PROTEIN KINASE; GRANZYME; ION; TRANSIENT RECEPTOR POTENTIAL CHANNEL M; TRPM2 PROTEIN, MOUSE;

ANIMAL; C57BL MOUSE; CALCIUM SIGNALING; CELL CULTURE; CELL POLARITY; CHEMISTRY; DEFICIENCY; DEGRANULATION; EXOCYTOSIS; GENETICS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMMUNOLOGY; KNOCKOUT MOUSE; METABOLISM; MOUSE; NATURAL KILLER CELL; PHYSIOLOGY; TANDEM MASS SPECTROMETRY;

ADENOSINE DIPHOSPHATE RIBOSE; ANIMALS; ANTIGENS, CD38; CALCIUM; CALCIUM SIGNALING; CELL DEGRANULATION; CELL POLARITY; CELLS, CULTURED; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYCLIC AMP-DEPENDENT PROTEIN KINASES; EXOCYTOSIS; GRANZYMES; IONS; KILLER CELLS, NATURAL; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; TANDEM MASS SPECTROMETRY; TRPM CATION CHANNELS;

EID: 84928015223     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep09482     Document Type: Article

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