Epilepsy of infancy with migrating focal seizures: Six patients treated with bromide

Seizure

Volumn 23, Issue 10, 2014, Pages 899-902

  Caraballo, Roberto ^a   Pasteris, María Constanza ^a   Fortini, Pablo Sebastian ^a   Portuondo, Ernesto ^b  

^a Hospital de Pediatria SAMIC Prof Dr Juan P Garrahan   (Argentina)

^b Hospital Pediátrico Universitario de Centro Habana   (Cuba)

Author keywords

Epileptic encephalopathy; Focal seizures; Infants; Multifocal seizures; Potassium bromide; Refractory epilepsy

Indexed keywords

CARBAMAZEPINE; CLOBAZAM; CLONAZEPAM; CORTICOTROPIN; ETIRACETAM; LAMOTRIGINE; PHENOBARBITAL; PHENYTOIN; POTASSIUM BROMIDE; RUFINAMIDE; TOPIRAMATE; VALPROIC ACID; ZONISAMIDE; ANTICONVULSIVE AGENT; BROMIDE; POTASSIUM DERIVATIVE;

ACNE; ANTICONVULSANT THERAPY; ARTICLE; CHILD; CLINICAL ARTICLE; COGNITIVE DEFECT; COMPUTER ASSISTED TOMOGRAPHY; DELTA RHYTHM; DROWSINESS; DRUG BLOOD LEVEL; DRUG DOSE REDUCTION; DRUG MONITORING; EPILEPSY OF INFANCY WITH MIGRATING FOCAL SEIZURE; EVOKED SOMATOSENSORY RESPONSE; FEMALE; FOCAL EPILEPSY; FOLLOW UP; HUMAN; INFANT; INFANT DISEASE; KETOGENIC DIET; LANGUAGE DISABILITY; MALE; MUSCLE HYPOTONIA; NEUROLOGIC EXAMINATION; NEWBORN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRESCHOOL CHILD; PRIORITY JOURNAL; PSYCHOMOTOR RETARDATION; THETA RHYTHM; TREATMENT RESPONSE; VOMITING; BRAIN; ELECTROENCEPHALOGRAPHY; EPILEPSIES, PARTIAL; PATHOPHYSIOLOGY; PROCEDURES; TREATMENT OUTCOME;

ANTICONVULSANTS; BRAIN; BROMIDES; CHILD; CHILD, PRESCHOOL; ELECTROENCEPHALOGRAPHY; EPILEPSIES, PARTIAL; FEMALE; HUMANS; MALE; POTASSIUM COMPOUNDS; TREATMENT OUTCOME;

EID: 84927973159     PISSN: 10591311     EISSN: 15322688     Source Type: Journal    
DOI: 10.1016/j.seizure.2014.06.016     Document Type: Article

References (13)

1. Coppola G, Plouin P, Chiron C, Robain O, Dulac O. Migrating partial seizures in infancy: A malignant disorder with developmental arrest. Epilepsia 1995;36: 1017-24.
2. Caraballo R, Fontana E, Darra F, Cassar L, Negrini F, Fiorini E, et al. Bernardina migrating focal seizures in infancy: Analysis of the electroclinical pattern in 17 patients. J Child Neurol 2008;23(5):497-506.
3. Djuric M, Kravljanac R, Kovacevik G, Martic J. The efficacy of bromides, stir-ipentol and levetiracetam in two patients with malignant migrating partial seizures in infancy. Epileptic Disord 2011;13:22-6.
4. Vendrame M, Podori A, Loddenkemper T, Kluger G, Coppola G, Kothare V. Treatment of malignant migrating partial epilepsy of infancy with rufinamide: report of five cases. Epileptic Disord 2011;13:18-21.
5. Merdariu D, Delanoe C, Mahfoufi N, Bellavoine V, Auvin S. Malignant migrating partial seizures of infancy controlled by stiripentol and clonazepam. Brain Dev 2013;35:177-80.
6. Striano P, Coppola G, Zara F, Nabbout R. Genetic heterogeneity in malignant partial seizures of infancy. Ann Neurol 2014. http://dx.doi.org/10.1002/ana.24055.
7. Woody RC. Bromide therapy for pediatric seizure disorder intractable to other antiepileptic drugs. J Child Neurol 1990;5(1):65-7.
8. Browne T, Leduc B, Kosta Rokosz M, Bromfield E, Ramsay RE, Toledo J. Trimethadione, paraldehyde, phenacemide, bromides, sulthiame, acetazol- Amide, and methsuximide. In: Engel J, Pedley T, editors. Epilepsy: A compre- hensive textbook. 2nd ed. Philadelphia: Lippincott Williams & Wilkins; 2008 . p. 1703-19.
9. Okuda K, Yasuhara A, Kamei A, Araki A, Kitamura N, Kobayashi Y. Successful control with bromide of two patients with malignant migrating partial seizures in infancy. Brain Dev 2000;22:56-9.
10. Nabatame S, Saito Y, Sakuma H, Komaki H, Nakagawa E, Sugai K, et al. Bromoderma in a patient with migrating partial seizures in infancy. Epilepsy Res 2010;91:283-8.
11. Unver O, Incecik F, Dundar H, Komur M, Unver A, Okuyaz C. Potassium bromide for treatment of malignant migrating partial seizures in infancy. Pediatr Neurol 2013;49:355-7.
12. Oguni H, Hayashi K, Oguni M, Mukahira A, Uehara T, Fukuyama Y, et al. Treatment of severe myoclonic epilepsy in infancy and it's borderline variant with bromide. Epilepsia 1994;35:1140-5.
13. Korinthenberg R, Burkart P, Woelfle C, Moenting JS, Ernst JP. Pharmacology, efficacy, and tolerability of potassium bromide in childhood epilepsy. J Child Neurol 2007;22:414-8.