메뉴 건너뛰기




Volumn 47, Issue 6, 2014, Pages 383-393

Preclinical modeling of primal emotional affects (SEEKING, PANIC and PLAY): Gateways to the development of new treatments for depression

Author keywords

Affective neuroscience; Brain; Deep brain stimulation; Depression; GLYX 13; PANIC system; PLAY system; Preclinical models; SEEKING system

Indexed keywords

ANTIDEPRESSANT AGENT; BUPRENORPHINE; GLYX-13 PEPTIDE; NARCOTIC ANALGESIC AGENT; OLIGOPEPTIDE;

EID: 84927959943     PISSN: 02544962     EISSN: 1423033X     Source Type: Journal    
DOI: 10.1159/000366208     Document Type: Article
Times cited : (37)

References (80)
  • 3
    • 84858043246 scopus 로고    scopus 로고
    • Rethinking the emotional brain
    • LeDoux J: rethinking the emotional brain Neuron 2012; 73: 653-676.
    • (2012) Neuron , vol.73 , pp. 653-676
    • Ledoux, J.1
  • 4
    • 84927970741 scopus 로고    scopus 로고
    • Emotion
    • Oxford Oxford University Press
    • Rolls E: emotion and Decision Making Explained Oxford, Oxford University Press, 2014.
    • (2014) Decision Making Explained
    • Rolls, E.1
  • 5
    • 0008896977 scopus 로고
    • Hypothalamic integration of behavior, rewards punishments and related psychobiological process
    • in Morgane PJ, Panksepp J (eds New York, Dekker part A: behavioral studies of the hypothalamus
    • Panksepp J Hypothalamic integration of behavior, rewards punishments and related psychobiological process; in Morgane PJ, Panksepp J (eds): Handbook of the Hypothalamus New York, Dekker, 1981, vol 3, part A: behavioral studies of the hypothalamus, pp 289-487.
    • (1981) Handbook of the Hypothalamus , vol.3 , pp. 289-487
    • Panksepp, J.1
  • 6
    • 0020446120 scopus 로고
    • Toward a general psychobiological theory of emotions
    • Panksepp J: toward a general psychobiological theory of emotions: behav Brain Res 1982; 5: 407-422.
    • (1982) Behav Brain Res , vol.5 , pp. 407-422
    • Panksepp, J.1
  • 7
    • 80052543500 scopus 로고    scopus 로고
    • Cross-species affective neuroscience decoding of the primal affective experiences of humans and related animals
    • Panksepp J Cross-species affective neuroscience decoding of the primal affective experiences of humans and related animals PLoS One 2011; 6: e21236.
    • (2011) PLoS One , vol.6 , pp. e21236
    • Panksepp, J.1
  • 8
    • 80053102925 scopus 로고    scopus 로고
    • The basic emotional circuits of mammalian brains Do animals have affective lives?
    • Panksepp J the basic emotional circuits of mammalian brains: do animals have affective lives? Neurosci Biobehav Rev 2011; 35: 1791-1804.
    • (2011) Neurosci Biobehav Rev , vol.35 , pp. 1791-1804
    • Panksepp, J.1
  • 9
    • 79952675671 scopus 로고    scopus 로고
    • The neurobiology of social loss in animals some keys to the puzzle of psychic pain in humans
    • in MacDonald G Jensen-Campbell LA (eds Washington American Psychological Association
    • Panksepp J the neurobiology of social loss in animals some keys to the puzzle of psychic pain in humans; in MacDonald G, Jensen-Campbell LA (eds): Social Pain Neuropsychological and Health Implications of Loss and Exclusion Washington, American Psychological Association, 2011, pp 11-51.
    • (2011) Social Pain Neuropsychological and Health Implications of Loss and Exclusion , pp. 11-51
    • Panksepp, J.1
  • 10
    • 14844286442 scopus 로고    scopus 로고
    • Affective consciousness: Core emotional feelings in animals and humans: Consc
    • Panksepp J Affective consciousness: Core emotional feelings in animals and humans: consc Cogn 2005; 14: 30-80.
    • (2005) Cogn , vol.14 , pp. 30-80
    • Panksepp, J.1
  • 11
    • 33646929072 scopus 로고    scopus 로고
    • Emotional endophenotypes in evolutionary psychiatry
    • Panksepp J: emotional endophenotypes in evolutionary psychiatry: prog Neuropsychopharmacol Biol Psychiatry 2006; 30: 774-784.
    • (2006) Prog Neuropsychopharmacol Biol Psychiatry , vol.30 , pp. 774-784
    • Panksepp, J.1
  • 12
    • 84925448260 scopus 로고    scopus 로고
    • Affective neuroscience strategies for understanding and treating depressions: From preclinical models to novel therapeutics
    • Panksepp J, Wright JS, Dobrossy MD, Schlaepfer TE, Coenen VA Affective neuroscience strategies for understanding and treating depressions: from preclinical models to novel therapeutics J Clin Psychol 2014; 2: 472-494.
    • (2014) J Clin Psychol , vol.2 , pp. 472-494
    • Panksepp, J.1    Wright, J.S.2    Dobrossy, M.D.3    Schlaepfer, T.E.4    Coenen, V.A.5
  • 13
    • 0000119551 scopus 로고
    • Mood changes
    • in Vinken P, Bruyn G, Klawans H (eds Amsterdam Elsevier
    • Panksepp J Mood changes; in Vinken P, Bruyn G, Klawans H (eds): Handbook of Clinical Neurology Amsterdam, Elsevier, 1985, vol 45, pp 271-285.
    • (1985) Handbook of Clinical Neurology , vol.45 , pp. 271-285
    • Panksepp, J.1
  • 14
    • 0014440086 scopus 로고
    • Sensations evoked by stimulation in the midbrain of man
    • Nashold BS, Wilson WP, Slaughter DG: sensations evoked by stimulation in the midbrain of man J Neurosurg 1969; 30: 14-24.
    • (1969) J Neurosurg , vol.30 , pp. 14-24
    • Nashold, B.S.1    Wilson, W.P.2    Slaughter, D.G.3
  • 15
    • 84865140555 scopus 로고    scopus 로고
    • Human medial forebrain bundle mfb and anterior thalamic radiation atr, imaging of two major subcortical pathways and the dynamic balance of opposite affects in understanding depression
    • Coenen VA, Panksepp J, Hurwitz TA, Urbach H, Madler B Human medial forebrain bundle MFB and anterior thalamic radiation ATR, imaging of two major subcortical pathways and the dynamic balance of opposite affects in understanding depression J Neuropsychiatr Clin Neurosci 2012; 24: 223-236.
    • (2012) J Neuropsychiatr Clin Neurosci , vol.24 , pp. 223-236
    • Coenen, V.A.1    Panksepp, J.2    Hurwitz, T.A.3    Urbach, H.4    Madler, B.5
  • 16
    • 80052527923 scopus 로고    scopus 로고
    • Cross-species affective functions of the medial forebrain bundle - Implications for the treatment of affective pain and depression in humans
    • Coenen VA, Schlaepfer TE, Maedler B, Panksepp J Cross-species affective functions of the medial forebrain bundle - implications for the treatment of affective pain and depression in humans Neurosci Biobehav Rev 2011; 35: 1971-1981.
    • (2011) Neurosci Biobehav Rev , vol.35 , pp. 1971-1981
    • Coenen, V.A.1    Schlaepfer, T.E.2    Maedler, B.3    Panksepp, J.4
  • 18
    • 84858176303 scopus 로고    scopus 로고
    • The vicissitudes of preclinical psychiatric research, justified abandonment by big pharma?
    • Panksepp J the vicissitudes of preclinical psychiatric research, justified abandonment by big pharma? Future Neurol 2012; 7: 1-3.
    • (2012) Future Neurol , vol.7 , pp. 1-3
    • Panksepp, J.1
  • 19
    • 78650678814 scopus 로고    scopus 로고
    • Depression, an evolutionarily conserved mechanism to terminate separation-distress? A review of aminergic, peptidergic and neural network perspectives
    • Watt DF, Panksepp J Depression, an evolutionarily conserved mechanism to terminate separation-distress? A review of aminergic, peptidergic and neural network perspectives Neuropsychoanalysis 2009; 11: 7-51.
    • (2009) Neuropsychoanalysis , vol.11 , pp. 7-51
    • Watt, D.F.1    Panksepp, J.2
  • 20
    • 0004233756 scopus 로고
    • Loss New York Basic Books Loss, sadness and depression
    • Bowlby J Attachment and Loss New York, Basic Books, 1980, vol 3: Loss, sadness and depression
    • (1980) Attachment , vol.3
    • Bowlby, J.1
  • 21
    • 0002565093 scopus 로고
    • Brain opioids, a neurochemical substrate for narcotic and social dependence
    • in Cooper S (ed London Academic Press
    • Panksepp J Brain opioids, a neurochemical substrate for narcotic and social dependence; in Cooper S (ed): Progress in Theory in Psychopharmacology London, Academic Press, 1981, pp 149-175.
    • (1981) Progress in Theory in Psychopharmacology , pp. 149-175
    • Panksepp, J.1
  • 22
    • 84884591828 scopus 로고    scopus 로고
    • Pain and suicidality: Insights from reward and addiction neuroscience
    • Elman I, Borsook D, Volkow ND Pain and suicidality: insights from reward and addiction neuroscience: prog Neurobiol 2013; 109: 1-27.
    • (2013) Prog Neurobiol , vol.109 , pp. 1-27
    • Elman, I.1    Borsook, D.2    Volkow, N.D.3
  • 23
    • 84880047087 scopus 로고    scopus 로고
    • Buprenorphine - Clinically useful but often misunderstood
    • Butler S Buprenorphine - clinically useful but often misunderstood Scand J Pain 2013; 4: 148-152.
    • (2013) Scand J Pain , vol.4 , pp. 148-152
    • Butler, S.1
  • 26
    • 0020331584 scopus 로고
    • Possible antidepressive effects of opioids: Action of buprenorphine
    • Emrich HM, Vogt P, Herz A Possible antidepressive effects of opioids: action of buprenorphine Ann NY Acad Sci 1982; 398: 108-112.
    • (1982) Ann NY Acad Sci , vol.398 , pp. 108-112
    • Emrich, H.M.1    Vogt, P.2    Herz, A.3
  • 27
    • 33645367848 scopus 로고
    • Positive reinforcement produced by electrical stimulation of the septal area and other regions of rat brain
    • Olds J, Milner P Positive reinforcement produced by electrical stimulation of the septal area and other regions of rat brain J Comp Physiol Psychol 1954; 47: 419-427.
    • (1954) J Comp Physiol Psychol , vol.47 , pp. 419-427
    • Olds, J.1    Milner, P.2
  • 28
    • 84973986000 scopus 로고
    • Neuroleptics and operant behavior the anhedonia hypothesis
    • Wise RA Neuroleptics and operant behavior the anhedonia hypothesis: behav Brain Sci 1982; 5: 39-53.
    • (1982) Behav Brain Sci , vol.5 , pp. 39-53
    • Wise, R.A.1
  • 29
    • 80053116694 scopus 로고    scopus 로고
    • Toward affective circuit-based preclinical models of depression: Sensitizing dorsal pag arousal leads to sustained suppression of positive affect in rats
    • Wright JS, Panksepp J: toward affective circuit-based preclinical models of depression: sensitizing dorsal PAG arousal leads to sustained suppression of positive affect in rats Neurosci Biobehav Rev 2011; 35: 1902-1915.
    • (2011) Neurosci Biobehav Rev , vol.35 , pp. 1902-1915
    • Wright, J.S.1    Panksepp, J.2
  • 30
    • 0025970096 scopus 로고
    • What psychological process mediates feeding evoked by electrical stimulation of the lateral hypothalamus?: Behave
    • Berridge KC, Valenstein ES: what psychological process mediates feeding evoked by electrical stimulation of the lateral hypothalamus?: behav Neurosci 1991; 105: 2-14.
    • (1991) Neurosci , vol.105 , pp. 2-14
    • Berridge, K.C.1    Valenstein, E.S.2
  • 31
    • 85145854713 scopus 로고    scopus 로고
    • Dopamine and seeking: Subcortical reward systems and appetitive urges
    • in Elliot A (ed New York Taylor & Francis
    • Panksepp J, Moskal J: dopamine and SEEKING: subcortical reward systems and appetitive urges; in Elliot A (ed): Handbook of Approach and Avoidance Motivation New York, Taylor & Francis, 2008, pp 67-87.
    • (2008) Handbook of Approach and Avoidance Motivation , pp. 67-87
    • Panksepp, J.1    Moskal, J.2
  • 32
    • 36949041038 scopus 로고    scopus 로고
    • Deep brain stimulation to reward circuitry alleviates anhedonia in refractory major depression
    • Schlaepfer TE, et al Deep brain stimulation to reward circuitry alleviates anhedonia in refractory major depression Neuropsychopharmacology 2008; 33: 368-377.
    • (2008) Neuropsychopharmacology , vol.33 , pp. 368-377
    • Schlaepfer, T.E.1
  • 33
    • 0141924584 scopus 로고    scopus 로고
    • Feeling the pain of social loss
    • Panksepp J Feeling the pain of social loss Science 2003; 302: 237-239.
    • (2003) Science , vol.302 , pp. 237-239
    • Panksepp, J.1
  • 34
    • 0019072005 scopus 로고
    • Social deprivation and play in rats
    • Panksepp J, Beatty WW Social deprivation and play in rats: behav Neurosci 1980; 30: 197-206.
    • (1980) Behav Neurosci , vol.30 , pp. 197-206
    • Panksepp, J.1    Beatty, W.W.2
  • 35
    • 0042383410 scopus 로고    scopus 로고
    • Laughing rats and the evolutionary antecedents of human joy?
    • Panksepp J, Burgdorf J: Laughing rats and the evolutionary antecedents of human joy?: physiol Behav 2003; 79: 533-547.
    • (2003) Physiol Behav , vol.79 , pp. 533-547
    • Panksepp, J.1    Burgdorf, J.2
  • 36
    • 75649094887 scopus 로고    scopus 로고
    • Communication of adult rats by ultrasonic vocalization, biological, sociobiological and neuroscience approaches
    • Brudzynski SM: communication of adult rats by ultrasonic vocalization, biological, sociobiological and neuroscience approaches ILAR J 2009; 50: 43-50.
    • (2009) ILAR J , vol.50 , pp. 43-50
    • Brudzynski, S.M.1
  • 37
    • 34347206487 scopus 로고    scopus 로고
    • Neuroevolutionary sources of laughter and social joy: Modeling primal human laughter in laboratory rats
    • Panksepp J Neuroevolutionary sources of laughter and social joy: modeling primal human laughter in laboratory rats: behav Brain Res 2007; 182: 231-244.
    • (2007) Behav Brain Res , vol.182 , pp. 231-244
    • Panksepp, J.1
  • 38
    • 0033914542 scopus 로고    scopus 로고
    • Anticipation of rewarding electrical brain stimulation evokes ultrasonic vocalizations in rats
    • Burgdorf J, Knutson B, Panksepp J Anticipation of rewarding electrical brain stimulation evokes ultrasonic vocalizations in rats: behav Neurosci 2000; 114: 320-327.
    • (2000) Behav Neurosci , vol.114 , pp. 320-327
    • Burgdorf, J.1    Knutson, B.2    Panksepp, J.3
  • 39
  • 40
    • 0032013123 scopus 로고    scopus 로고
    • Anticipation of play elicits high-frequency ultrasonic vocalizations in young rats
    • Knutson B, Burgdorf J, Panksepp J Anticipation of play elicits high-frequency ultrasonic vocalizations in young rats J Comp Psychol 1998; 112: 65-73.
    • (1998) J Comp Psychol , vol.112 , pp. 65-73
    • Knutson, B.1    Burgdorf, J.2    Panksepp, J.3
  • 41
    • 0022855712 scopus 로고
    • The role of ultrasonic vocalizations in the regulation of reproduction in rats
    • Barfield RJ, Thomas DA the role of ultrasonic vocalizations in the regulation of reproduction in rats Ann NY Acad Sci 1986; 474: 33-43.
    • (1986) Ann NY Acad Sci , vol.474 , pp. 33-43
    • Barfield, R.J.1    Thomas, D.A.2
  • 42
    • 0034899168 scopus 로고    scopus 로고
    • Nucleus accumbens amphetamine microinjections unconditionally elicit 50-khz ultrasonic vocalizations in rats
    • Burgdorf J, Knutson B, Panksepp J, Ikemoto S Nucleus accumbens amphetamine microinjections unconditionally elicit 50-kHz ultrasonic vocalizations in rats: behav Neurosci 2001; 115: 40-944.
    • (2001) Behav Neurosci , vol.115 , pp. 40-944
    • Burgdorf, J.1    Knutson, B.2    Panksepp, J.3    Ikemoto, S.4
  • 43
    • 79957831271 scopus 로고    scopus 로고
    • Positive affective vocalizations during cocaine and sucrose self-Administration, a model for spontaneous drug desire in rats
    • Browning JR, Browning DA, Maxwell AO, Dong Y, Jansen HT, Panksepp J, Sorg BA Positive affective vocalizations during cocaine and sucrose self-Administration, a model for spontaneous drug desire in rats Neuropharmacology 2011; 61: 268-275.
    • (2011) Neuropharmacology , vol.61 , pp. 268-275
    • Browning, J.R.1    Browning, D.A.2    Maxwell, A.O.3    Dong, Y.4    Jansen, H.T.5    Panksepp, J.6    Sorg, B.A.7
  • 44
    • 34548611424 scopus 로고    scopus 로고
    • Neurobiology of 50-khz ultrasonic vocalizations in rats, electrode mapping lesion and pharmacology studies
    • Burgdorf J, Wood PL, Kroes RA, Moskal JR, Panksepp J Neurobiology of 50-kHz ultrasonic vocalizations in rats, electrode mapping lesion and pharmacology studies: behav Brain Res 2007; 182: 274-283.
    • (2007) Behav Brain Res , vol.182 , pp. 274-283
    • Burgdorf, J.1    Wood, P.L.2    Kroes, R.A.3    Moskal, J.R.4    Panksepp, J.5
  • 45
    • 33746900423 scopus 로고    scopus 로고
    • The mesolimbic dopamine reward circuit in depression
    • Nestler EJ, Carlezon WA Jr the mesolimbic dopamine reward circuit in depression: biol Psychiatry 2006; 59: 1151-1159.
    • (2006) Biol Psychiatry , vol.59 , pp. 1151-1159
    • Nestler, E.J.1    Carlezon, W.A.2
  • 46
    • 77955838052 scopus 로고    scopus 로고
    • Identification of multiple call categories within the rich repertoire of adult rat 50-khz ultrasonic vocalizations: Effects of amphetamine and social context
    • Wright JM, Gourdon JC, Clarke PBS Identification of multiple call categories within the rich repertoire of adult rat 50-kHz ultrasonic vocalizations: effects of amphetamine and social context Psychopharmacology 2010; 21: 1-13.
    • (2010) Psychopharmacology , vol.21 , pp. 1-13
    • Wright, J.M.1    Gourdon, J.C.2    Clarke, P.B.S.3
  • 47
    • 56749150859 scopus 로고    scopus 로고
    • Ultrasonic vocalizations of rats rattus norvegicus during mating play and aggression: Behavioral concomitants relationship to reward and self-Administration of playback
    • Burgdorf J, Kroes RA, Moskal JR, Pfaus JG, Brudzynski SM, Panksepp J Ultrasonic vocalizations of rats Rattus norvegicus during mating play and aggression: behavioral concomitants relationship to reward and self-Administration of playback J Comp Psychol 2008; 122: 357-367.
    • (2008) J Comp Psychol , vol.122 , pp. 357-367
    • Burgdorf, J.1    Kroes, R.A.2    Moskal, J.R.3    Pfaus, J.G.4    Brudzynski, S.M.5    Panksepp, J.6
  • 48
    • 72049129407 scopus 로고    scopus 로고
    • Ultrasonic communication in rats: Effects of morphine and naloxone on vocal and behavioral responses to playback of 50-khz vocalizations
    • Wohr M, Schwarting RKW Ultrasonic communication in rats: effects of morphine and naloxone on vocal and behavioral responses to playback of 50-kHz vocalizations: pharmacol Biochem Behav 2009; 94: 285-295.
    • (2009) Pharmacol Biochem Behav , vol.94 , pp. 285-295
    • Wohr, M.1    Schwarting, R.K.W.2
  • 49
    • 76249116316 scopus 로고    scopus 로고
    • New insights into the relationship of neurogenesis and affect: Tickling induces hippocampal cell proliferation in rats emitting appetitive 50-khz ultrasonic vocalizations
    • Wohr M, Kehl M, Borta A, Schanzer A, Schwarting RK, Hoglinger GU New insights into the relationship of neurogenesis and affect: Tickling induces hippocampal cell proliferation in rats emitting appetitive 50-kHz ultrasonic vocalizations Neuroscience 2009; 163: 1024-1030.
    • (2009) Neuroscience , vol.163 , pp. 1024-1030
    • Wohr, M.1    Kehl, M.2    Borta, A.3    Schanzer, A.4    Schwarting, R.K.5    Hoglinger, G.U.6
  • 50
    • 0033826201 scopus 로고    scopus 로고
    • 50-khz chirping laughter? in response to conditioned and unconditioned tickle-induced reward in rats, effects of social housing and genetic variables
    • Panksepp J, Burgdorf J: 50-kHz chirping laughter? In response to conditioned and unconditioned tickle-induced reward in rats, effects of social housing and genetic variables: behav Brain Res 2000; 115: 25-38.
    • (2000) Behav Brain Res , vol.115 , pp. 25-38
    • Panksepp, J.1    Burgdorf, J.2
  • 51
    • 80053119292 scopus 로고    scopus 로고
    • Frequency-modulated 50 khz ultrasonic vocalizations a tool for uncovering the molecular substrates of positive affect
    • Burgdorf J, Panksepp J, Moskal JR Frequency-modulated 50 kHz ultrasonic vocalizations A tool for uncovering the molecular substrates of positive affect Neurosci Biobehav Rev 2011; 35: 1831-1836.
    • (2011) Neurosci Biobehav Rev , vol.35 , pp. 1831-1836
    • Burgdorf, J.1    Panksepp, J.2    Moskal, J.R.3
  • 52
    • 80053108650 scopus 로고    scopus 로고
    • A novel nmda receptor glycine-site partial agonist, glyx-13, has therapeutic potential for the treatment of autism
    • Moskal JR, Burgdorf J, Kroes RA, Brudzynski SM, Panksepp J A novel NMDA receptor glycine-site partial agonist, GLYX-13, has therapeutic potential for the treatment of autism Neurosci Biobehav Rev 2011; 35: 1982-1988.
    • (2011) Neurosci Biobehav Rev , vol.35 , pp. 1982-1988
    • Moskal, J.R.1    Burgdorf, J.2    Kroes, R.A.3    Brudzynski, S.M.4    Panksepp, J.5
  • 53
    • 77953122243 scopus 로고    scopus 로고
    • Uncovering the molecular basis of positive affect using rough-And-Tumble play in rats a role for insulin-like growth factor i
    • Burgdorf J, Kroes RA, Beinfeld MC, Panksepp J, Moskal JR Uncovering the molecular basis of positive affect using rough-And-Tumble play in rats A role for insulin-like growth factor I Neuroscience 2010; 168: 769-777.
    • (2010) Neuroscience , vol.168 , pp. 769-777
    • Burgdorf, J.1    Kroes, R.A.2    Beinfeld, M.C.3    Panksepp, J.4    Moskal, J.R.5
  • 54
    • 34548649507 scopus 로고    scopus 로고
    • Tickling-induced 50-khz ultrasonic vocalization is individually stable and predicts behaviour in tests of anxiety and depression in rats
    • Mallo T, Matrov D, Herm L, Koiv K, Eller M, Rinken A, Harro J: Tickling-induced 50-kHz ultrasonic vocalization is individually stable and predicts behaviour in tests of anxiety and depression in rats: behav Brain Res 2007; 184: 57-71.
    • (2007) Behav Brain Res , vol.184 , pp. 57-71
    • Mallo, T.1    Matrov, D.2    Herm, L.3    Koiv, K.4    Eller, M.5    Rinken, A.6    Harro, J.7
  • 56
    • 80053108650 scopus 로고    scopus 로고
    • A novel nmda receptor glycine-site partial agonist glyx-13 has therapeutic potential for the treatment of autism
    • Moskal JR, Burgdorf J, Kroes RA, Brudzynski SM, Panksepp J A novel NMDA receptor glycine-site partial agonist GLYX-13 has therapeutic potential for the treatment of autism Neurosci Biobehav Rev 2011; 35: 1982-1988.
    • (2011) Neurosci Biobehav Rev , vol.35 , pp. 1982-1988
    • Moskal, J.R.1    Burgdorf, J.2    Kroes, R.A.3    Brudzynski, S.M.4    Panksepp, J.5
  • 57
    • 80053119292 scopus 로고    scopus 로고
    • Frequency-modulated 50 khz ultrasonic vocalizations, a tool for uncovering the molecular substrates of positive affect
    • Burgdorf J, Panksepp J, Moskal JR Frequency-modulated 50 kHz ultrasonic vocalizations, a tool for uncovering the molecular substrates of positive affect Neurosci Biobehav Rev 2011; 35: 1831-1836.
    • (2011) Neurosci Biobehav Rev , vol.35 , pp. 1831-1836
    • Burgdorf, J.1    Panksepp, J.2    Moskal, J.R.3
  • 58
    • 41149085932 scopus 로고    scopus 로고
    • Playback of 22- and 50-khz ultrasonic vocalizations induces differential c-fos expression in rat brain
    • Sadananda M, Wohr M, Schwarting RKW Playback of 22- And 50-kHz ultrasonic vocalizations induces differential c-fos expression in rat brain Neurosci Lett 2008; 435: 17-23.
    • (2008) Neurosci Lett , vol.435 , pp. 17-23
    • Sadananda, M.1    Wohr, M.2    Schwarting, R.K.W.3
  • 59
    • 0028868414 scopus 로고
    • An air-puff stimulus method for elicitation of ultrasonic vocalizations in rats
    • Knapp DJ, Pohorecky LA an air-puff stimulus method for elicitation of ultrasonic vocalizations in rats J Neurosci Methods 1995; 62: 1-5.
    • (1995) J Neurosci Methods , vol.62 , pp. 1-5
    • Knapp, D.J.1    Pohorecky, L.A.2
  • 60
    • 84865128037 scopus 로고    scopus 로고
    • The effect of intermittent alcohol vapor or pulsatile heroin on somatic and negative affective indices during spontaneous withdrawal in wistar rats
    • Williams AM, Reis DJ, Powell AS, Neira LJ, Nealey KA, Ziegler CE, Walker BM the effect of intermittent alcohol vapor or pulsatile heroin on somatic and negative affective indices during spontaneous withdrawal in Wistar rats Psychopharmacology 2012; 223: 75-88.
    • (2012) Psychopharmacology , vol.223 , pp. 75-88
    • Williams, A.M.1    Reis, D.J.2    Powell, A.S.3    Neira, L.J.4    Nealey, K.A.5    Ziegler, C.E.6    Walker, B.M.7
  • 61
    • 31444435465 scopus 로고    scopus 로고
    • Animal models of depression and antidepressant activity
    • Markou A Animal models of depression and antidepressant activity Neurosci Biobehav Rev 2005; 29: issue 4-5.
    • (2005) Neurosci Biobehav Rev , vol.29 , Issue.4-5
    • Markou, A.1
  • 63
    • 84881313914 scopus 로고    scopus 로고
    • Glutamate modulators as potential therapeutic drugs in schizophrenia and affective disorders
    • Hashimoto K, Malchow B, Falkai P, Schmitt A Glutamate modulators as potential therapeutic drugs in schizophrenia and affective disorders Eur Arch Psychiatry Clin Neurosci 2013; 263: 367-377.
    • (2013) Eur Arch Psychiatry Clin Neurosci , vol.263 , pp. 367-377
    • Hashimoto, K.1    Malchow, B.2    Falkai, P.3    Schmitt, A.4
  • 65
    • 77449090704 scopus 로고    scopus 로고
    • Stress hormone regulation: Biological role and translation into therapy
    • Holsboer F, Ising M Stress hormone regulation: biological role and translation into therapy Annu Rev Psychol 2010; 61: 81-109.
    • (2010) Annu Rev Psychol , vol.61 , pp. 81-109
    • Holsboer, F.1    Ising, M.2
  • 66
    • 40849130056 scopus 로고    scopus 로고
    • Central crh system in depression and anxiety - Evidence from clinical studies with crh1 receptor antagonists
    • Holsboer F, Ising M Central CRH system in depression and anxiety - evidence from clinical studies with CRH1 receptor antagonists Eur J Pharmacol 2008; 583: 350-357.
    • (2008) Eur J Pharmacol , vol.583 , pp. 350-357
    • Holsboer, F.1    Ising, M.2
  • 67
    • 0023933648 scopus 로고
    • The drug treatment of anxiety and depression
    • Cole JO the drug treatment of anxiety and depression Med Clin North Am 1988; 72: 815-830.
    • (1988) Med Clin North Am , vol.72 , pp. 815-830
    • Cole, J.O.1
  • 68
    • 29344431565 scopus 로고    scopus 로고
    • Comorbid anxiety and depression
    • Pollack MH Comorbid anxiety and depression J Clin Psychiatry 2005; 66(suppl 8): 22-29.
    • (2005) J Clin Psychiatry , vol.66 , pp. 22-29
    • Pollack, M.H.1
  • 70
    • 79955045808 scopus 로고    scopus 로고
    • Why does depression hurt? Ancestral primary-process separationdistress (PANIC) and diminished brain reward (SEEKING) processes in the genesis of depressive affect
    • Panksepp J, Watt J why does depression hurt? Ancestral primary-process separationdistress (PANIC) and diminished brain reward (SEEKING) processes in the genesis of depressive affect psychiatry 2011; 74: 5-14.
    • (2011) Psychiatry , vol.74 , pp. 5-14
    • Panksepp, J.1    Watt, J.2
  • 71
    • 0032423613 scopus 로고    scopus 로고
    • What is the role of dopamine in reward: Hedonic impact, reward learning, or incentive salience?
    • Berridge KC, Robinson TE: what is the role of dopamine in reward: hedonic impact, reward learning, or incentive salience? Brain Res Rev 1998; 28: 309-369.
    • (1998) Brain Res Rev , vol.28 , pp. 309-369
    • Berridge, K.C.1    Robinson, T.E.2
  • 73
    • 32444439058 scopus 로고    scopus 로고
    • Behavioral theories and the neurophysiology of reward
    • Schultz W: behavioral theories and the neurophysiology of reward Annu Rev Psychol 2005; 57: 87-115.
    • (2005) Annu Rev Psychol , vol.57 , pp. 87-115
    • Schultz, W.1
  • 74
    • 0033461157 scopus 로고    scopus 로고
    • The role of nucleus accumbens dopamine in motivated behavior a unifying interpretation with special reference to reward-seeking
    • Ikemoto S, Panksepp J the role of nucleus accumbens dopamine in motivated behavior A unifying interpretation with special reference to reward-seeking Brain Res Rev 1999; 31: 6-41.
    • (1999) Brain Res Rev , vol.31 , pp. 6-41
    • Ikemoto, S.1    Panksepp, J.2
  • 75
    • 84863527786 scopus 로고    scopus 로고
    • An evolutionary framework to understand foraging, wanting, and desire the neuropsychology of the seeking system
    • Wright JS, Panksepp J an evolutionary framework to understand foraging, wanting, and desire the neuropsychology of the SEEKING system Neuropsychoanalysis 2012; 14: 5-39.
    • (2012) Neuropsychoanalysis , vol.14 , pp. 5-39
    • Wright, J.S.1    Panksepp, J.2
  • 76
    • 84927964429 scopus 로고    scopus 로고
    • On seeking a foundational source of affective, behavioral and cognitive enthusiasm, volition, and will-power
    • Panksepp J, Wright JS On SEEKING A foundational source of affective, behavioral and cognitive enthusiasm, volition, and will-power Neuropsychoanalysis 2012; 1: 59-75.
    • (2012) Neuropsychoanalysis , vol.1 , pp. 59-75
    • Panksepp, J.1    Wright, J.S.2
  • 77
    • 79955465492 scopus 로고    scopus 로고
    • Panksepp j the resting-state hypo thesis of major depressive disorder - A translational subcortical-cortical framework for a system disorder
    • Northoff G, Wiebking C, Feinberg T, Panksepp J the resting-state hypothesis of major depressive disorder - A translational subcortical-cortical framework for a system disorder Neurosci Biobehav Rev 2011; 35: 1929-1945.
    • (2011) Neurosci Biobehav Rev , vol.35 , pp. 1929-1945
    • Northoff, G.1    Wiebking, C.2    Feinberg, T.3
  • 78
    • 72049086941 scopus 로고    scopus 로고
    • The reward circuit: Linking primate anatomy and human imaging
    • Haber SN, Knutson B the reward circuit: linking primate anatomy and human imaging Neuropsychopharmacology 2010; 35: 4-26.
    • (2010) Neuropsychopharmacology , vol.35 , pp. 4-26
    • Haber, S.N.1    Knutson, B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.