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Volumn 26, Issue 6, 2015, Pages 675-680

Novel hybrids from N-hydroxyarylamide and indole ring through click chemistry as histone deacetylase inhibitors with potent antitumor activities

Author keywords

Anti tumor agents; Click chemistry; Histone deacetylase inhibitors; N Hydroxyarylamides; Synthesis

Indexed keywords


EID: 84927914516     PISSN: 10018417     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cclet.2015.03.015     Document Type: Article
Times cited : (29)

References (27)
  • 1
    • 84903581670 scopus 로고    scopus 로고
    • Targeting histone deacetylases for cancer therapy: from molecular mechanisms to clinical implications
    • Z. Li, and W.G. Zhu Targeting histone deacetylases for cancer therapy: from molecular mechanisms to clinical implications Int. J. Biol. Sci. 10 2014 757 770
    • (2014) Int. J. Biol. Sci. , vol.10 , pp. 757-770
    • Li, Z.1    Zhu, W.G.2
  • 2
    • 33644856123 scopus 로고    scopus 로고
    • Epigenetic therapy of cancer: past, present and future
    • C.B. Yoo, and P.A. Jones Epigenetic therapy of cancer: past, present and future Nat. Rev. Drug Discov. 5 2006 37 50
    • (2006) Nat. Rev. Drug Discov. , vol.5 , pp. 37-50
    • Yoo, C.B.1    Jones, P.A.2
  • 3
    • 84929166052 scopus 로고    scopus 로고
    • Targeting the histone orthography of cancer: drugs for writers, erasers and readers
    • L. Simó-Riudalbas, and M. Esteller Targeting the histone orthography of cancer: drugs for writers, erasers and readers, Br J. Pharmacol. 172 2015 2716 2732
    • (2015) Br, J. Pharmacol. , vol.172 , pp. 2716-2732
    • Simó-Riudalbas, L.1    Esteller, M.2
  • 4
    • 0036386359 scopus 로고    scopus 로고
    • Histone acetyltransferases and deacetylases in the control of cell proliferation and differentiation
    • H. Lehrmann, L.L. Pritchard, A. Harel-Bellan, and et al. Histone acetyltransferases and deacetylases in the control of cell proliferation and differentiation Adv. Cancer Res. 86 2002 41 65
    • (2002) Adv. Cancer Res. , vol.86 , pp. 41-65
    • Lehrmann, H.1    Pritchard, L.L.2    Harel-Bellan, A.3
  • 6
    • 61849144810 scopus 로고    scopus 로고
    • HDAC family: what are the cancer relevant targets
    • O. Witt, H.E. Deubzer, T. Milde, I. Oehme, and et al. HDAC family: what are the cancer relevant targets Cancer Lett. 277 2009 8 21
    • (2009) Cancer Lett. , vol.277 , pp. 8-21
    • Witt, O.1    Deubzer, H.E.2    Milde, T.3    Oehme, I.4
  • 7
    • 84905238187 scopus 로고    scopus 로고
    • Histone deacetylase inhibitor (HDACI) mechanisms of action: emerging insights
    • P. Bose, Y. Dai, and S. Grant Histone deacetylase inhibitor (HDACI) mechanisms of action: emerging insights Pharmacol. Ther. 143 2014 323 336
    • (2014) Pharmacol. Ther. , vol.143 , pp. 323-336
    • Bose, P.1    Dai, Y.2    Grant, S.3
  • 8
    • 84892942381 scopus 로고    scopus 로고
    • New and emerging HDAC inhibitors for cancer treatment
    • A.C. West, and R.W. Johnstone New and emerging HDAC inhibitors for cancer treatment J. Clin. Invest. 124 2014 30 39
    • (2014) J. Clin. Invest. , vol.124 , pp. 30-39
    • West, A.C.1    Johnstone, R.W.2
  • 9
    • 84891837817 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors: an overview of the clinical studies in solid tumors
    • M. Slingerland, H.J. Guchelaar, and H. Gelderblom Histone deacetylase inhibitors: an overview of the clinical studies in solid tumors Anticancer Drugs 25 2014 140 149
    • (2014) Anticancer Drugs , vol.25 , pp. 140-149
    • Slingerland, M.1    Guchelaar, H.J.2    Gelderblom, H.3
  • 10
    • 33847258674 scopus 로고    scopus 로고
    • Discovery and development of SAHA as an anticancer agent
    • P.A. Marks Discovery and development of SAHA as an anticancer agent Oncogene 26 2007 1351 1356
    • (2007) Oncogene , vol.26 , pp. 1351-1356
    • Marks, P.A.1
  • 11
    • 84937481590 scopus 로고    scopus 로고
    • FK228
    • FK228: http://www.fda.gov/NewsEvents/Newsroom/Press Announcements/2009/ucm189629.htm.
  • 12
    • 84874094984 scopus 로고    scopus 로고
    • Effects of treatment with histone deacetylase inhibitors in solid tumors: a review based on 30 clinical trials
    • T. Qiu, L. Zhou, W. Zhu, and et al. Effects of treatment with histone deacetylase inhibitors in solid tumors: a review based on 30 clinical trials Future Oncol. 9 2013 255 269
    • (2013) Future Oncol. , vol.9 , pp. 255-269
    • Qiu, T.1    Zhou, L.2    Zhu, W.3
  • 13
    • 84894577774 scopus 로고    scopus 로고
    • Design, synthesis, and biological evaluation of N-hydroxycinnamamide/salicylic acid hybrids as histone deacetylase inhibitors
    • T. You, K. Chen, F.H. Wang, and et al. Design, synthesis, and biological evaluation of N-hydroxycinnamamide/salicylic acid hybrids as histone deacetylase inhibitors Chin. Chem. Lett. 25 2014 474 478
    • (2014) Chin. Chem. Lett. , vol.25 , pp. 474-478
    • You, T.1    Chen, K.2    Wang, F.H.3
  • 15
    • 77955643796 scopus 로고    scopus 로고
    • The clinical development of histone deacetylase inhibitors as targeted anticancer drugs
    • P.A. Marks The clinical development of histone deacetylase inhibitors as targeted anticancer drugs Expert Opin. Invest. Drugs 19 2010 1049 1066
    • (2010) Expert Opin. Invest. Drugs , vol.19 , pp. 1049-1066
    • Marks, P.A.1
  • 16
    • 84901706232 scopus 로고    scopus 로고
    • Belinostat for the treatment of peripheral T-cell lymphomas
    • J. McDermott, and A. Jimeno Belinostat for the treatment of peripheral T-cell lymphomas Drugs Today (Barc.) 50 2014 337 345
    • (2014) Drugs Today (Barc.) , vol.50 , pp. 337-345
    • McDermott, J.1    Jimeno, A.2
  • 17
    • 79960113305 scopus 로고    scopus 로고
    • Phase I and pharmacodynamic study of an orally administered novel inhibitor of histone deacetylases, SB939, in patients with refractory solid malignancies
    • W.P. Yong, B.C. Goh, R.A. Soo, and et al. Phase I and pharmacodynamic study of an orally administered novel inhibitor of histone deacetylases, SB939, in patients with refractory solid malignancies Ann. Oncol. 22 2011 2516 2522
    • (2011) Ann. Oncol. , vol.22 , pp. 2516-2522
    • Yong, W.P.1    Goh, B.C.2    Soo, R.A.3
  • 18
    • 58149183232 scopus 로고    scopus 로고
    • Phase I pharmacokinetic and pharmacodynamic study of LAQ824, a hydroxamate histone deacetylase inhibitor with a heat shock protein-90 inhibitory profile, in patients with advanced solid tumors
    • J.S. de Bono, R. Kristeleit, A. Tolcher, and et al. Phase I pharmacokinetic and pharmacodynamic study of LAQ824, a hydroxamate histone deacetylase inhibitor with a heat shock protein-90 inhibitory profile, in patients with advanced solid tumors Clin. Cancer Res. 14 2008 6663 6673
    • (2008) Clin. Cancer Res. , vol.14 , pp. 6663-6673
    • De Bono, J.S.1    Kristeleit, R.2    Tolcher, A.3
  • 19
    • 84881085302 scopus 로고    scopus 로고
    • Pharmacokinetic/pharmacodynamic modelling-based optimisation of administration schedule for the histone deacetylase inhibitor abexinostat (S78454/PCI-24781) in phase I
    • S. Fouliard, R. Robert, A. Jacquet-Bescond, and et al. Pharmacokinetic/pharmacodynamic modelling-based optimisation of administration schedule for the histone deacetylase inhibitor abexinostat (S78454/PCI-24781) in phase I Eur. J. Cancer 49 2013 2791 2797
    • (2013) Eur. J. Cancer , vol.49 , pp. 2791-2797
    • Fouliard, S.1    Robert, R.2    Jacquet-Bescond, A.3
  • 20
    • 79957933972 scopus 로고    scopus 로고
    • Pharmacokinetics, safety and inducible cytokine responses during a phase 1 trial of the oral histone deacetylase inhibitor ITF2357 (givinostat)
    • A. Furlan, V. Monzani, L.L. Reznikov, and et al. Pharmacokinetics, safety and inducible cytokine responses during a phase 1 trial of the oral histone deacetylase inhibitor ITF2357 (givinostat) Mol. Med. 17 2011 353 362
    • (2011) Mol. Med. , vol.17 , pp. 353-362
    • Furlan, A.1    Monzani, V.2    Reznikov, L.L.3
  • 21
    • 37249071337 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors in cancer treatment: a review of the clinical toxicity and the modulation of gene expression in cancer cell
    • Ø. Bruserud, C. Stapnes, E. Ersvaer, and et al. Histone deacetylase inhibitors in cancer treatment: a review of the clinical toxicity and the modulation of gene expression in cancer cell Curr. Pharm. Biotechnol. 8 2007 388 400
    • (2007) Curr. Pharm. Biotechnol. , vol.8 , pp. 388-400
    • Bruserud, Ø.1    Stapnes, C.2    Ersvaer, E.3
  • 22
    • 84987660604 scopus 로고    scopus 로고
    • Bis-indole derivatives with antitumor activity turn out to be specific ligands of human telomeric G-quadruplex
    • J. Amato, N. Iaccarino, B. Pagano, and et al. Bis-indole derivatives with antitumor activity turn out to be specific ligands of human telomeric G-quadruplex Front. Chem. 2 2014 54
    • (2014) Front. Chem. , vol.2 , pp. 54
    • Amato, J.1    Iaccarino, N.2    Pagano, B.3
  • 23
    • 84885173028 scopus 로고    scopus 로고
    • Synthesis and biological evaluation of indole-based, anti-cancer agents inspired by the vascular disrupting agent 2-(3′-hydroxy-4′-methoxyphenyl)-3-(3″,4Prime;,5Prime;-trimethoxybenzoyl)-6-methoxyindole (OXi8006)
    • M.T. Macdonough, T.E. Strecker, E. Hamel, and et al. Synthesis and biological evaluation of indole-based, anti-cancer agents inspired by the vascular disrupting agent 2-(3′-hydroxy-4′-methoxyphenyl)-3-(3″,4Prime;,5Prime;-trimethoxybenzoyl)-6-methoxyindole (OXi8006) Bioorg. Med. Chem. 21 2013 6831 6843
    • (2013) Bioorg. Med. Chem. , vol.21 , pp. 6831-6843
    • Macdonough, M.T.1    Strecker, T.E.2    Hamel, E.3
  • 24
    • 77950582432 scopus 로고    scopus 로고
    • Conformational refinement of hydroxamate-based histone deacetylase inhibitors and exploration of 3-piperidin-3-ylindole analogues of dacinostat (LAQ824)
    • Y.S. Cho, L. Whitehead, J. Li, and et al. Conformational refinement of hydroxamate-based histone deacetylase inhibitors and exploration of 3-piperidin-3-ylindole analogues of dacinostat (LAQ824) J. Med. Chem. 53 2010 2952 2963
    • (2010) J. Med. Chem. , vol.53 , pp. 2952-2963
    • Cho, Y.S.1    Whitehead, L.2    Li, J.3
  • 25
    • 51649102031 scopus 로고    scopus 로고
    • Click chemistry, a powerful tool for pharmaceutical sciences
    • C.D. Hein, X.M. Liu, and D. Wang Click chemistry, a powerful tool for pharmaceutical sciences Pharm. Res. 25 2008 2216 2230
    • (2008) Pharm. Res. , vol.25 , pp. 2216-2230
    • Hein, C.D.1    Liu, X.M.2    Wang, D.3
  • 26
    • 39549111477 scopus 로고    scopus 로고
    • Click chemistry reactions in medicinal chemistry: applications of the 1,3-dipolar cycloaddition between azides and alkynes
    • G.C. Tron, T. Pirali, R.A. Billington, and et al. Click chemistry reactions in medicinal chemistry: applications of the 1,3-dipolar cycloaddition between azides and alkynes Med. Res. Rev. 28 2008 278 308
    • (2008) Med. Res. Rev. , vol.28 , pp. 278-308
    • Tron, G.C.1    Pirali, T.2    Billington, R.A.3
  • 27
    • 78651250721 scopus 로고    scopus 로고
    • Efficient access to new chemical space through flow-construction of druglike macrocycles through copper-surface-catalyzed azide-alkyne cycloaddition reactions
    • A.R. Bogdan, and K. James Efficient access to new chemical space through flow-construction of druglike macrocycles through copper-surface-catalyzed azide-alkyne cycloaddition reactions Chemistry 16 2010 14506 14512
    • (2010) Chemistry , vol.16 , pp. 14506-14512
    • Bogdan, A.R.1    James, K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.