Nifedipine plus candesartan combination increases blood pressure control regardless of race and improves the side effect profile: DISTINCTrandomized trial results

Journal of Hypertension

Volumn 32, Issue 12, 2014, Pages 2488-2498

  Kjeldsen, Sverre E ^a   Sica, Domenic ^b   Haller, Hermann ^c   Cha, Gloria ^d   Gil Extremera, Blas ^e   Harvey, Peter ^f   Heyvaert, Frank ^g   Lewin, Andrew J ^h   Villa, Giuseppe ⁱ   Mancia, Giuseppe ^j  

^a ULLEVÅL UNIVERSITY HOSPITAL   (Norway)

^b VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^c HANNOVER MEDICAL SCHOOL   (Germany)

^d KRK Medical Research Institute   (United States)

^e HOSPITAL UNIVERSITARIO SAN CECILIO   (Spain)

^f Crouch Oak Family Practice   (United Kingdom)

^g Huisartsenpraktijk de Regenboog   (Belgium)

^h NATIONAL RESEARCH INSTITUTE   (United States)

ⁱ IRCCS   (Italy)

^j UNIVERSITY OF MILANO BICOCCA   (Italy)

more..

Author keywords

Candesartan cilexetil; Combination therapy; DISTINCT study; Essential hypertension; Nifedipine GITS; Vasodilatory side effects

Indexed keywords

CANDESARTAN HEXETIL; NIFEDIPINE; PLACEBO; ANTIHYPERTENSIVE AGENT; BENZIMIDAZOLE DERIVATIVE; BIPHENYL DERIVATIVE; CANDESARTAN; TETRAZOLE DERIVATIVE;

ADULT; AGED; ANTIHYPERTENSIVE THERAPY; ARTICLE; BLOOD PRESSURE REGULATION; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG SAFETY; DRUG WITHDRAWAL; FEMALE; HEADACHE; HOT FLUSH; HUMAN; HYPERTENSION; HYPOTENSION; LOW DRUG DOSE; MAJOR CLINICAL STUDY; MALE; MEAN ARTERIAL PRESSURE; MIDDLE AGED; MONOTHERAPY; MULTICENTER STUDY; OUTCOME ASSESSMENT; PERIPHERAL EDEMA; POLYPHARMACY; PRIORITY JOURNAL; RACE DIFFERENCE; RANDOMIZED CONTROLLED TRIAL; RESPONSE SURFACE METHOD; SYSTOLIC BLOOD PRESSURE; ADVERSE DRUG REACTION; BLOOD PRESSURE; CLINICAL TRIAL; DRUG COMBINATION; ETHNIC GROUP; ORAL DRUG ADMINISTRATION; TREATMENT OUTCOME;

ADMINISTRATION, ORAL; AGED; ANTIHYPERTENSIVE AGENTS; BENZIMIDAZOLES; BIPHENYL COMPOUNDS; BLOOD PRESSURE; DOUBLE-BLIND METHOD; DRUG THERAPY, COMBINATION; DRUG-RELATED SIDE EFFECTS AND ADVERSE REACTIONS; ETHNIC GROUPS; FEMALE; HUMANS; HYPERTENSION; MALE; MIDDLE AGED; NIFEDIPINE; TETRAZOLES; TREATMENT OUTCOME;

EID: 84927743127     PISSN: 02636352     EISSN: 14735598     Source Type: Journal    
DOI: 10.1097/HJH.0000000000000331     Document Type: Article

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