Tight junction disruption by cadmium in an in vitro human airway tissue model

Respiratory Research

Volumn 16, Issue 1, 2015, Pages

  Cao, Xuefei ^a   Lin, Haixia ^a   Muskhelishvili, Levan ^b   Latendresse, John ^b   Richter, Patricia ^c   Heflich, Robert H ^d  

^a NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

^b Toxicologic Pathology Associates   (United States)

^c CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

^d Division of Genetic and Reproductive Toxicology   (United States)

Author keywords

Airway air liquid interface (ALI) culture; Cadmium; Intracellular junctional interacting proteins; Occludin phosphorylation; Tight junction

Indexed keywords

CADMIUM CHLORIDE; OCCLUDIN; PROTEIN KINASE C; PROTEIN ZO1; OCLN PROTEIN, HUMAN; PROTEIN KINASE INHIBITOR; PROTEIN TYROSINE KINASE; TJP1 PROTEIN, HUMAN;

ARTICLE; CONTROLLED STUDY; CYTOSKELETON; CYTOTOXICITY; DOWN REGULATION; GENE EXPRESSION; HISTOPATHOLOGY; HOMEOSTASIS; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; ONCOGENE SRC; PROTEIN PHOSPHORYLATION; RESPIRATORY EPITHELIUM; SIGNAL TRANSDUCTION; TIGHT JUNCTION; ANTAGONISTS AND INHIBITORS; BRONCHUS; CELL CULTURE; DOSE RESPONSE; DRUG EFFECTS; EPITHELIUM CELL; GENE EXPRESSION REGULATION; GENETICS; IMPEDANCE; LUNG GAS EXCHANGE; METABOLISM; PATHOLOGY; PHOSPHORYLATION; TIME FACTOR;

BLOOD-AIR BARRIER; BRONCHI; CADMIUM CHLORIDE; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRIC IMPEDANCE; EPITHELIAL CELLS; GENE EXPRESSION REGULATION; HUMANS; OCCLUDIN; PHOSPHORYLATION; PROTEIN KINASE C; PROTEIN KINASE INHIBITORS; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES; TIGHT JUNCTIONS; TIME FACTORS; ZONULA OCCLUDENS-1 PROTEIN;

EID: 84927740982     PISSN: 14659921     EISSN: 1465993X     Source Type: Journal    
DOI: 10.1186/s12931-015-0191-9     Document Type: Article

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