메뉴 건너뛰기




Volumn 20, Issue 1, 2015, Pages 11-19

The effect of intravenous peramivir, compared with oral oseltamivir, on the outcome of post-influenza pneumococcal pneumonia in mice

Author keywords

[No Author keywords available]

Indexed keywords

CXCL1 CHEMOKINE; CXCL3 CHEMOKINE; GAMMA INTERFERON; INTERLEUKIN 6; OSELTAMIVIR; PERAMIVIR; TUMOR NECROSIS FACTOR ALPHA; ANTIVIRUS AGENT; CHEMOKINE; CXCL2 CHEMOKINE; CXCL2 PROTEIN, MOUSE; CYCLOPENTANE DERIVATIVE; GUANIDINE DERIVATIVE; KERATINOCYTE DERIVED CHEMOKINE;

EID: 84927712976     PISSN: 13596535     EISSN: 20402058     Source Type: Journal    
DOI: 10.3851/IMP2744     Document Type: Article
Times cited : (13)

References (47)
  • 1
    • 84871511126 scopus 로고    scopus 로고
    • Deaths: Preliminary data for 2011
    • Hoyert DL, Xu J. Deaths: preliminary data for 2011. Natl Vital Stat Rep 2012; 61:1-51.
    • (2012) Natl Vital Stat Rep , vol.61 , pp. 1-51
    • Hoyert, D.L.1    Xu, J.2
  • 2
    • 84859350846 scopus 로고    scopus 로고
    • Antivirals for treatment of influenza: A systematic review and meta-analysis of observational studies
    • Hsu J, Santesso N, Mustafa R, et al. Antivirals for treatment of influenza: a systematic review and meta-analysis of observational studies. Ann Intern Med 2012; 156:512-524.
    • (2012) Ann Intern Med , vol.156 , pp. 512-524
    • Hsu, J.1    Santesso, N.2    Mustafa, R.3
  • 3
    • 33947398779 scopus 로고    scopus 로고
    • Neuraminidase inhibitors improve outcome of patients with leukemia and influenza: An observational study
    • Chemaly RF, Torres HA, Aguilera EA, et al. Neuraminidase inhibitors improve outcome of patients with leukemia and influenza: an observational study. Clin Infect Dis 2007; 44:964-967.
    • (2007) Clin Infect Dis , vol.44 , pp. 964-967
    • Chemaly, R.F.1    Torres, H.A.2    Aguilera, E.A.3
  • 4
    • 79960757788 scopus 로고    scopus 로고
    • Oseltamivir and risk of lower respiratory tract complications in patients with flu symptoms: A meta-analysis of eleven randomized clinical trials
    • Hernán MA, Lipsitch M. Oseltamivir and risk of lower respiratory tract complications in patients with flu symptoms: a meta-analysis of eleven randomized clinical trials. Clin Infect Dis 2011; 53:277-279.
    • (2011) Clin Infect Dis , vol.53 , pp. 277-279
    • Hernán, M.A.1    Lipsitch, M.2
  • 5
    • 84873697558 scopus 로고    scopus 로고
    • Impact of neuraminidase inhibitor treatment on outcomes of public health importance during the 2009-2010 influenza A(H1N1) pandemic; a systematic review and meta-analysis in hospitalized patients
    • Muthuri SG, Myles PR, Venkatesan S, Leonardi-Bee J, Nguyen-Van-Tam JS. Impact of neuraminidase inhibitor treatment on outcomes of public health importance during the 2009-2010 influenza A(H1N1) pandemic; a systematic review and meta-analysis in hospitalized patients. J Infect Dis 2013; 207:553-563.
    • (2013) J Infect Dis , vol.207 , pp. 553-563
    • Muthuri, S.G.1    Myles, P.R.2    Venkatesan, S.3    Leonardi-Bee, J.4    Nguyen-Van-Tam, J.S.5
  • 6
    • 84856112765 scopus 로고    scopus 로고
    • Antiviral therapy and outcomes of patients with pneumonia caused by influenza A pandemic (H1N1) virus
    • Yang SG, Cao B, Liang LR, et al. Antiviral therapy and outcomes of patients with pneumonia caused by influenza A pandemic (H1N1) virus. PLoS ONE 2012; 7:e29652.
    • (2012) PLoS ONE , vol.7
    • Yang, S.G.1    Cao, B.2    Liang, L.R.3
  • 7
    • 84867554833 scopus 로고    scopus 로고
    • Treatment with neuraminidase inhibitors for critically ill patients with influenza A(H1N1)pdm09
    • Louie JK, Yang S, Acosta M, et al. Treatment with neuraminidase inhibitors for critically ill patients with influenza A(H1N1)pdm09. Clin Infect Dis 2012; 55:1198-1204.
    • (2012) Clin Infect Dis , vol.55 , pp. 1198-1204
    • Louie, J.K.1    Yang, S.2    Acosta, M.3
  • 8
    • 77957330450 scopus 로고    scopus 로고
    • Effectiveness of oseltamivir on disease progression and viral RNA shedding in patients with mild pandemic 2009 influenza A H1N1: Opportunistic retrospective study of medical charts in China
    • Yu H, Liao Q, Yuan Y, et al. Effectiveness of oseltamivir on disease progression and viral RNA shedding in patients with mild pandemic 2009 influenza A H1N1: opportunistic retrospective study of medical charts in China. BMJ 2010; 341:c4779.
    • (2010) BMJ , vol.341
    • Yu, H.1    Liao, Q.2    Yuan, Y.3
  • 9
    • 63649087759 scopus 로고    scopus 로고
    • Seasonal influenza in adults and children-diagnosis, treatment, chemoprophylaxis, and institutional outbreak management: Clinical practice guidelines of the infectious diseases society of America
    • Harper SA, Bradley JS, Englund JA, et al. Seasonal influenza in adults and children-diagnosis, treatment, chemoprophylaxis, and institutional outbreak management: clinical practice guidelines of the Infectious Diseases Society of America. Clin Infect Dis 2009; 48:1003-1032.
    • (2009) Clin Infect Dis , vol.48 , pp. 1003-1032
    • Harper, S.A.1    Bradley, J.S.2    Englund, J.A.3
  • 10
    • 79953723442 scopus 로고    scopus 로고
    • A single intramuscular injection of neuraminidase inhibitor peramivir demonstrates antiviral activity against novel pandemic A/California/04/2009 (H1N1) influenza virus infection in mice
    • Bantia S, Kellogg D, Parker C, Upshaw R, Ilyushina NA, Babu YS. A single intramuscular injection of neuraminidase inhibitor peramivir demonstrates antiviral activity against novel pandemic A/California/04/2009 (H1N1) influenza virus infection in mice. Antiviral Res 2011; 90:17-21.
    • (2011) Antiviral Res , vol.90 , pp. 17-21
    • Bantia, S.1    Kellogg, D.2    Parker, C.3    Upshaw, R.4    Ilyushina, N.A.5    Babu, Y.S.6
  • 11
    • 41649105849 scopus 로고    scopus 로고
    • Injectable peramivir mitigates disease and promotes survival in ferrets and mice infected with the highly virulent influenza virus, A/ vietnam/1203/04 (H5N1)
    • Yun NE, Linde NS, Zacks MA, et al. Injectable peramivir mitigates disease and promotes survival in ferrets and mice infected with the highly virulent influenza virus, A/ Vietnam/1203/04 (H5N1). Virology 2008; 374:198-209.
    • (2008) Virology , vol.374 , pp. 198-209
    • Yun, N.E.1    Linde, N.S.2    Zacks, M.A.3
  • 12
    • 65349186033 scopus 로고    scopus 로고
    • Update: Drug susceptibility of swine-origin influenza A (H1N1) viruses, april 2009
    • Centers for Disease Control and Prevention. Update: drug susceptibility of swine-origin influenza A (H1N1) viruses, April 2009. MMWR Morb Mortal Wkly Rep 2009; 58:433-435.
    • (2009) MMWR Morb Mortal Wkly Rep , vol.58 , pp. 433-435
  • 13
    • 73349121665 scopus 로고    scopus 로고
    • The emergency use authorization of peramivir for treatment of 2009 H1N1 influenza
    • Birnkrant D, Cox E. The Emergency Use Authorization of peramivir for treatment of 2009 H1N1 influenza. N Engl J Med 2009; 361:2204-2207.
    • (2009) N Engl J Med , vol.361 , pp. 2204-2207
    • Birnkrant, D.1    Cox, E.2
  • 14
    • 79953766801 scopus 로고    scopus 로고
    • Clinical experience in adults and children treated with intravenous peramivir for 2009 influenza A (H1N1) under an emergency IND program in the United States
    • Hernandez JE, Adiga R, Armstrong R, et al. Clinical experience in adults and children treated with intravenous peramivir for 2009 influenza A (H1N1) under an Emergency IND program in the United States. Clin Infect Dis 2011; 52:695-706.
    • (2011) Clin Infect Dis , vol.52 , pp. 695-706
    • Hernandez, J.E.1    Adiga, R.2    Armstrong, R.3
  • 15
    • 79956299861 scopus 로고    scopus 로고
    • Intravenous peramivir for treatment of influenza A and B virus infection in high-risk patients
    • Kohno S, Kida H, Mizuguchi M, et al. Intravenous peramivir for treatment of influenza A and B virus infection in high-risk patients. Antimicrob Agents Chemother 2011; 55:2803-2812.
    • (2011) Antimicrob Agents Chemother , vol.55 , pp. 2803-2812
    • Kohno, S.1    Kida, H.2    Mizuguchi, M.3
  • 16
    • 78049293276 scopus 로고    scopus 로고
    • Efficacy and safety of intravenous peramivir for treatment of seasonal influenza virus infection
    • Kohno S, Kida H, Mizuguchi M, Shimada J. Efficacy and safety of intravenous peramivir for treatment of seasonal influenza virus infection. Antimicrob Agents Chemother 2010; 54:4568-4574.
    • (2010) Antimicrob Agents Chemother , vol.54 , pp. 4568-4574
    • Kohno, S.1    Kida, H.2    Mizuguchi, M.3    Shimada, J.4
  • 17
    • 80054709041 scopus 로고    scopus 로고
    • Phase III randomized, double-blind study comparing single-dose intravenous peramivir with oral oseltamivir in patients with seasonal influenza virus infection
    • Kohno S, Yen MY, Cheong HJ, et al. Phase III randomized, double-blind study comparing single-dose intravenous peramivir with oral oseltamivir in patients with seasonal influenza virus infection. Antimicrob Agents Chemother 2011; 55:5267-5276.
    • (2011) Antimicrob Agents Chemother , vol.55 , pp. 5267-5276
    • Kohno, S.1    Yen, M.Y.2    Cheong, H.J.3
  • 18
    • 84862169991 scopus 로고    scopus 로고
    • Emergency use authorization for intravenous peramivir: Evaluation of safety in the treatment of hospitalized patients infected with 2009 H1N1 influenza A virus
    • Sorbello A, Jones SC, Carter W, et al. Emergency use authorization for intravenous peramivir: evaluation of safety in the treatment of hospitalized patients infected with 2009 H1N1 influenza A virus. Clin Infect Dis 2012; 55:1-7.
    • (2012) Clin Infect Dis , vol.55 , pp. 1-7
    • Sorbello, A.1    Jones, S.C.2    Carter, W.3
  • 19
    • 0035002429 scopus 로고    scopus 로고
    • Decreased pulmonary clearance of S. Pneumoniae following influenza A infection in mice
    • LeVine AM, Koeningsknecht V, Stark JM. Decreased pulmonary clearance of S. pneumoniae following influenza A infection in mice. J Virol Methods 2001; 94:173-186.
    • (2001) J Virol Methods , vol.94 , pp. 173-186
    • LeVine, A.M.1    Koeningsknecht, V.2    Stark, J.M.3
  • 20
    • 33746483285 scopus 로고    scopus 로고
    • Insights into the interaction between influenza virus and pneumococcus
    • McCullers JA. Insights into the interaction between influenza virus and pneumococcus. Clin Microbiol Rev 2006; 19:571-582.
    • (2006) Clin Microbiol Rev , vol.19 , pp. 571-582
    • McCullers, J.A.1
  • 21
    • 0031004806 scopus 로고    scopus 로고
    • Alveolar macrophages are required for protective pulmonary defenses in murine klebsiella pneumonia: Elimination of alveolar macrophages increases neutrophil recruitment but decreases bacterial clearance and survival
    • Broug-Holub E, Toews GB, van Iwaarden J F, et al. Alveolar macrophages are required for protective pulmonary defenses in murine Klebsiella pneumonia: elimination of alveolar macrophages increases neutrophil recruitment but decreases bacterial clearance and survival. Infect Immun 1997; 65:1139-1146.
    • (1997) Infect Immun , vol.65 , pp. 1139-1146
    • Broug-Holub, E.1    Toews, G.B.2    Van Iwaarden, J.F.3
  • 22
    • 51849103407 scopus 로고    scopus 로고
    • Predominant role of bacterial pneumonia as a cause of death in pandemic influenza: Implications for pandemic influenza preparedness
    • Morens DM, Taubenberger JK, Fauci AS. Predominant role of bacterial pneumonia as a cause of death in pandemic influenza: implications for pandemic influenza preparedness. J Infect Dis 2008; 198:962-970.
    • (2008) J Infect Dis , vol.198 , pp. 962-970
    • Morens, D.M.1    Taubenberger, J.K.2    Fauci, A.S.3
  • 23
    • 77950492924 scopus 로고    scopus 로고
    • Influenza virus infection decreases tracheal mucociliary velocity and clearance of streptococcus pneumoniae
    • Pittet LA, Hall-Stoodley L, Rutkowski MR, Harmsen AG. Influenza virus infection decreases tracheal mucociliary velocity and clearance of Streptococcus pneumoniae. Am J Respir Cell Mol Biol 2010; 42:450-460.
    • (2010) Am J Respir Cell Mol Biol , vol.42 , pp. 450-460
    • Pittet, L.A.1    Hall-Stoodley, L.2    Rutkowski, M.R.3    Harmsen, A.G.4
  • 24
    • 22244471025 scopus 로고    scopus 로고
    • Influenza virus neuraminidase contributes to secondary bacterial pneumonia
    • Peltola VT, Murti KG, McCullers JA. Influenza virus neuraminidase contributes to secondary bacterial pneumonia. J Infect Dis 2005; 192:249-257.
    • (2005) J Infect Dis , vol.192 , pp. 249-257
    • Peltola, V.T.1    Murti, K.G.2    McCullers, J.A.3
  • 25
    • 0033121181 scopus 로고    scopus 로고
    • Influenza A virus accelerates neutrophil apoptosis and markedly potentiates apoptotic effects of bacteria
    • Colamussi ML, White MR, Crouch E, Hartshorn KL. Influenza A virus accelerates neutrophil apoptosis and markedly potentiates apoptotic effects of bacteria. Blood 1999; 93:2395-2403.
    • (1999) Blood , vol.93 , pp. 2395-2403
    • Colamussi, M.L.1    White, M.R.2    Crouch, E.3    Hartshorn, K.L.4
  • 26
    • 68849124811 scopus 로고    scopus 로고
    • Type I IFNs mediate development of postinfluenza bacterial pneumonia in mice
    • Shahangian A, Chow EK, Tian X, et al. Type I IFNs mediate development of postinfluenza bacterial pneumonia in mice. J Clin Invest 2009; 119:1910-1920.
    • (2009) J Clin Invest , vol.119 , pp. 1910-1920
    • Shahangian, A.1    Chow, E.K.2    Tian, X.3
  • 27
    • 80052383971 scopus 로고    scopus 로고
    • Synergistic stimulation of type I interferons during influenza virus coinfection promotes streptococcus pneumoniae colonization in mice
    • Nakamura S, Davis KM, Weiser JN. Synergistic stimulation of type I interferons during influenza virus coinfection promotes Streptococcus pneumoniae colonization in mice. J Clin Invest 2011; 121:3657-3665.
    • (2011) J Clin Invest , vol.121 , pp. 3657-3665
    • Nakamura, S.1    Davis, K.M.2    Weiser, J.N.3
  • 28
    • 33847330199 scopus 로고    scopus 로고
    • Induction of pro- and anti-inammatory molecules in a mouse model of pneumococcal pneumonia after influenza
    • Smith MW, Schmidt JE, Rehg JE, Orihuela CJ, McCullers JA. Induction of pro- and anti-inammatory molecules in a mouse model of pneumococcal pneumonia after influenza. Comp Med 2007; 57:82-89.
    • (2007) Comp Med , vol.57 , pp. 82-89
    • Smith, M.W.1    Schmidt, J.E.2    Rehg, J.E.3    Orihuela, C.J.4    McCullers, J.A.5
  • 29
    • 43249118968 scopus 로고    scopus 로고
    • Inhibition of pulmonary antibacterial defense by interferon-during recovery from influenza infection
    • Sun K, Metzger DW. Inhibition of pulmonary antibacterial defense by interferon-during recovery from influenza infection. Nat Med 2008; 14:558-564.
    • (2008) Nat Med , vol.14 , pp. 558-564
    • Sun, K.1    Metzger, D.W.2
  • 30
    • 3242812828 scopus 로고    scopus 로고
    • Effect of antiviral treatment on the outcome of secondary bacterial pneumonia after influenza
    • McCullers JA. Effect of antiviral treatment on the outcome of secondary bacterial pneumonia after influenza. J Infect Dis 2004; 190:519-526.
    • (2004) J Infect Dis , vol.190 , pp. 519-526
    • McCullers, J.A.1
  • 31
    • 0037443951 scopus 로고    scopus 로고
    • Role of neuraminidase in lethal synergism between influenza virus and streptococcus pneumoniae
    • McCullers JA, Bartmess KC. Role of neuraminidase in lethal synergism between influenza virus and Streptococcus pneumoniae. J Infect Dis 2003; 187:1000-1009.
    • (2003) J Infect Dis , vol.187 , pp. 1000-1009
    • McCullers, J.A.1    Bartmess, K.C.2
  • 32
    • 58849132964 scopus 로고    scopus 로고
    • Treatment with protein synthesis inhibitors improves outcomes of secondary bacterial pneumonia after influenza
    • Karlström A, Boyd KL, English BK, McCullers JA. Treatment with protein synthesis inhibitors improves outcomes of secondary bacterial pneumonia after influenza. J Infect Dis 2009; 199:311-319.
    • (2009) J Infect Dis , vol.199 , pp. 311-319
    • Karlström, A.1    Boyd, K.L.2    English, B.K.3    McCullers, J.A.4
  • 33
    • 77949741612 scopus 로고    scopus 로고
    • Clarithromycin inhibits type a seasonal influenza virus infection in human airway epithelial cells
    • Yamaya M, Shinya K, Hatachi Y, et al. Clarithromycin inhibits type a seasonal influenza virus infection in human airway epithelial cells. J Pharmacol Exp Ther 2010; 333:81-90.
    • (2010) J Pharmacol Exp Ther , vol.333 , pp. 81-90
    • Yamaya, M.1    Shinya, K.2    Hatachi, Y.3
  • 34
    • 0031954367 scopus 로고    scopus 로고
    • Therapeutic effect of erythromycin on influenza virus-induced lung injury in mice
    • Sato K, Suga M, Akaike T, et al. Therapeutic effect of erythromycin on influenza virus-induced lung injury in mice. Am J Respir Crit Care Med 1998; 157:853-857.
    • (1998) Am J Respir Crit Care Med , vol.157 , pp. 853-857
    • Sato, K.1    Suga, M.2    Akaike, T.3
  • 35
    • 84863651259 scopus 로고    scopus 로고
    • Macrolide therapy in respiratory viral infections
    • Min JY, Jang YJ. Macrolide therapy in respiratory viral infections. Mediators Inflamm 2012; 2012:649570.
    • (2012) Mediators Inflamm , vol.2012
    • Min, J.Y.1    Jang, Y.J.2
  • 36
    • 80054709261 scopus 로고    scopus 로고
    • Efficacy of single intravenous injection of peramivir against influenza B virus infection in ferrets and cynomolgus macaques
    • Kitano M, Itoh Y, Kodama M, et al. Efficacy of single intravenous injection of peramivir against influenza B virus infection in ferrets and cynomolgus macaques. Antimicrob Agents Chemother 2011; 55:4961-4970.
    • (2011) Antimicrob Agents Chemother , vol.55 , pp. 4961-4970
    • Kitano, M.1    Itoh, Y.2    Kodama, M.3
  • 37
    • 3543124246 scopus 로고    scopus 로고
    • Immunokinetics in severe pneumonia due to influenza virus and bacteria coinfection in mice
    • Seki M, Yanagihara K, Higashiyama Y, et al. Immunokinetics in severe pneumonia due to influenza virus and bacteria coinfection in mice. Eur Respir J 2004; 24:143-149.
    • (2004) Eur Respir J , vol.24 , pp. 143-149
    • Seki, M.1    Yanagihara, K.2    Higashiyama, Y.3
  • 38
    • 14744293108 scopus 로고    scopus 로고
    • Oseltamivir (Tamiflu) and its potential for use in the event of an influenza pandemic
    • Ward P, Small I, Smith J, Suter P, Dutkowski R. Oseltamivir (Tamiflu) and its potential for use in the event of an influenza pandemic. J Antimicrob Chemother 2005; 55:i5-i21.
    • (2005) J Antimicrob Chemother , vol.55 , pp. i5-i21
    • Ward, P.1    Small, I.2    Smith, J.3    Suter, P.4    Dutkowski, R.5
  • 39
    • 77954181158 scopus 로고    scopus 로고
    • Effectiveness and safety of neuraminidase inhibitors in reducing influenza complications: A meta-analysis of randomized controlled trials
    • Falagas ME, Koletsui PK, Vouloumanou EK, et al. Effectiveness and safety of neuraminidase inhibitors in reducing influenza complications: a meta-analysis of randomized controlled trials. J Antimicrob Chemother 2010; 65:1330-1346.
    • (2010) J Antimicrob Chemother , vol.65 , pp. 1330-1346
    • Falagas, M.E.1    Koletsui, P.K.2    Vouloumanou, E.K.3
  • 40
    • 29044434743 scopus 로고    scopus 로고
    • Anti-influenza virus activity of peramivir in mice with single intramuscular injection
    • Bantia S, Arnold CS, Parker CD, Upshaw R, Chand P. Anti-influenza virus activity of peramivir in mice with single intramuscular injection. Antiviral Res 2006; 69:39-45.
    • (2006) Antiviral Res , vol.69 , pp. 39-45
    • Bantia, S.1    Arnold, C.S.2    Parker, C.D.3    Upshaw, R.4    Chand, P.5
  • 41
    • 53249125778 scopus 로고    scopus 로고
    • Intramuscularly administered neuraminidase inhibitor peramivir is effective against lethal H5N1 influenza virus in mice
    • Boltz DA, Ilyushina NA, Arnold CS, Babu YS, Webster RG, Govorkova EA. Intramuscularly administered neuraminidase inhibitor peramivir is effective against lethal H5N1 influenza virus in mice. Antiviral Res 2008; 80:150-157.
    • (2008) Antiviral Res , vol.80 , pp. 150-157
    • Boltz, D.A.1    Ilyushina, N.A.2    Arnold, C.S.3    Babu, Y.S.4    Webster, R.G.5    Govorkova, E.A.6
  • 42
    • 84876226495 scopus 로고    scopus 로고
    • Efficacy of repeated intravenous injection of peramivir against influenza A (H1N1) 2009 virus infection in immunosuppressed mice
    • Kitano M, Kodama M, Itoh Y, et al. Efficacy of repeated intravenous injection of peramivir against influenza A (H1N1) 2009 virus infection in immunosuppressed mice. Antimicrob Agents Chemother 2013; 57:2286-2294.
    • (2013) Antimicrob Agents Chemother , vol.57 , pp. 2286-2294
    • Kitano, M.1    Kodama, M.2    Itoh, Y.3
  • 43
    • 84888193292 scopus 로고    scopus 로고
    • A clinical trial of intravenous peramivir compared with oral oseltamivir for the treatment of seasonal influenza in hospitalized adults
    • Ison MG, Hui DS, Clezy K, et al. A clinical trial of intravenous peramivir compared with oral oseltamivir for the treatment of seasonal influenza in hospitalized adults. Antivir Ther 2013; 18:651-661.
    • (2013) Antivir Ther , vol.18 , pp. 651-661
    • Ison, M.G.1    Hui, D.S.2    Clezy, K.3
  • 44
    • 0034720503 scopus 로고    scopus 로고
    • Efficacy and safety of oseltamivir in treatment of acute influenza: A randomized controlled trial
    • Neuraminidase Inhibitor Flu Treatment Investigator Group
    • Nicholson KG, Aoki F Y, Osterhaus AD, et al. Efficacy and safety of oseltamivir in treatment of acute influenza: a randomized controlled trial. Neuraminidase Inhibitor Flu Treatment Investigator Group. Lancet 2000; 355:1845-1850.
    • (2000) Lancet , vol.355 , pp. 1845-1850
    • Nicholson, K.G.1    Aoki, F.Y.2    Osterhaus, A.D.3
  • 45
    • 17744412173 scopus 로고    scopus 로고
    • Efficacy and safety of the oral neuraminidase inhibitor oseltamivir in treating acute influenza: A randomized controlled trial
    • US Oral Neuraminidase Study Group
    • Treanor JJ, Hayden FG, Vrooman PS, et al. Efficacy and safety of the oral neuraminidase inhibitor oseltamivir in treating acute influenza: a randomized controlled trial. US Oral Neuraminidase Study Group. JAMA 2000; 283:1016-1024.
    • (2000) JAMA , vol.283 , pp. 1016-1024
    • Treanor, J.J.1    Hayden, F.G.2    Vrooman, P.S.3
  • 46
    • 84878821350 scopus 로고    scopus 로고
    • Effect of double dose oseltamivir on clinical and virological outcomes in children and adults admitted to hospital with severe influenza: Double blind randomized controlled trial
    • South East Asia Infectious Disease Clinical Research Network. Effect of double dose oseltamivir on clinical and virological outcomes in children and adults admitted to hospital with severe influenza: double blind randomized controlled trial. BMJ 2013; 346:f3039.
    • (2013) BMJ , vol.346
  • 47
    • 84887863318 scopus 로고    scopus 로고
    • A prospective intervention study on higher-dose oseltamivir treatment in adults hospitalized with influenza A and B infections
    • Lee N, Hui DS, Zuo Z, et al. A prospective intervention study on higher-dose oseltamivir treatment in adults hospitalized with influenza A and B infections. Clin Infect Dis 2013; 57:1511-1519.
    • (2013) Clin Infect Dis , vol.57 , pp. 1511-1519
    • Lee, N.1    Hui, D.S.2    Zuo, Z.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.