Do postliver transplant patients need thromboprophylactic anticoagulation?

Clinical and Applied Thrombosis/Hemostasis

Volumn 20, Issue 7, 2014, Pages 673-677

  Mukerji, Amar Nath ^a   Karachristos, Andreas ^a   Maloo, Manoj ^a   Johnson, David ^a   Jain, Ashokkumar ^a  

^a TEMPLE UNIVERSITY HOSPITAL   (United States)

Author keywords

Anticoagulants; Deep venous thrombosis; Thrombosis prophylaxis; Venous thromboembolism

Indexed keywords

ANTICOAGULANT AGENT;

ANTICOAGULATION; ARTICLE; BLEEDING; BLOOD TRANSFUSION; BUDD CHIARI SYNDROME; DEEP VEIN THROMBOSIS; HEPATIC ARTERY THROMBOSIS; HUMAN; INTERNATIONAL NORMALIZED RATIO; LIVER TRANSPLANTATION; LUNG EMBOLISM; OPERATING ROOM; PORTAL VEIN THROMBOSIS; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; THROMBOCYTOPENIA; ADVERSE EFFECTS; BUDD-CHIARI SYNDROME; POSTOPERATIVE COMPLICATIONS; PULMONARY EMBOLISM;

ANTICOAGULANTS; BUDD-CHIARI SYNDROME; HUMANS; INTERNATIONAL NORMALIZED RATIO; LIVER TRANSPLANTATION; POSTOPERATIVE COMPLICATIONS; PULMONARY EMBOLISM;

EID: 84927700901     PISSN: 10760296     EISSN: 19382723     Source Type: Journal    
DOI: 10.1177/1076029614538490     Document Type: Article

References (38)

1. Gould MK, Garcia DA, Wren SM, et al; American College of Chest Physicians. Prevention of VTE in nonorthopedic surgical patients: antithrombotic therapy and prevention of thrombosis, 9th ed: American College of Chest Physicians evidence-based clinical practice guidelines. Chest. 2012;141:e227S-277S.
2. Northup PG, McMahon MM, Ruhl AP, et al. Coagulopathy does not fully protect hospitalized cirrhosis patients from peripheral venous thromboembolism. Am J Gastroenterol. 2006;101(7): 1524-1528; quiz 1680.
3. Cherian TP, Chiu K, Gunson B, et al. Pulmonary thromboembolism in liver transplantation: a retrospective review of the first 25 years. Transpl Int. 2010;23(11):1113-1119.
4. Ishitani M, Angle J, Bickston S, Caldwell S, Isaacs R, Pruett T. Liver transplantation: incidence and management of deep venous thrombosis and pulmonary emboli. Transplant Proc. 1997;29(7): 2861-2863.
5. Clagett GP, Anderson FA Jr, Geerts W, et al. Prevention of venous thromboembolism. Chest. 1998;114(5 suppl):531S-560S.
6. Donaldson GA, Williams C, Scannell JG, Shaw RS. A reappraisal of the application of the trendelenburg operation to massive fatal embolism. Report of a successful pulmonary-artery thrombectomy using a cardiopulmonary bypass. N Engl J Med. 1963;268: 171-174.
7. Collins R, Scrimgeour A, Yusuf S, Peto R. Reduction in fatal pulmonary embolism and venous thrombosis by perioperative administration of subcutaneous heparin. Overview of results of randomized trials in general, orthopedic, and urologic surgery. N Engl J Med. 1988;318(18):1162-1173.
8. Kakkar VV, Cohen AT, Edmonson RA, et al. Low molecular weight versus standard heparin for prevention of venous thromboembolism after major abdominal surgery. The thromboprophylaxis collaborative group. Lancet. 1993;341(8840):259-265.
9. Warkentin TE, Levine MN, Hirsh J, et al. Heparin-induced thrombocytopenia in patients treated with low-molecular-weight heparin or unfractionated heparin. N Engl J Med. 1995;332(20): 1330-1335.
10. Risk of and prophylaxis for venous thromboembolism in hospital patients. Thromboembolic risk factors (thrift) consensus group. BMJ. 1992;305(6853):567-574.
11. Oster G, Tuden RL, Colditz GA. Prevention of venous thromboembolism after general surgery. Cost-effectiveness analysis of alternative approaches to prophylaxis. Am J Med. 1987; 82(5):889-899.
12. Stahl RL, Duncan A, Hooks MA, Henderson JM, Millikan WJ, Warren WD. A hypercoagulable state follows orthotopic liver transplantation. Hepatology. 1990;12(3 pt 1):553-558.
13. Velasco F, Villalba R, Fernandez M, et al. Diminished anticoagulant and fibrinolytic activity following liver transplantation. Transplantation. 1992;53(6):1256-1261.
14. Liang TB, Bai XL, Li DL, Li JJ, Zheng SS. Early postoperative hemorrhage requiring urgent surgical reintervention after orthotopic liver transplantation. Transpl Proc. 2007;39(5):1549-1553.
15. Hendriks HG, van der Meer J, de Wolf JT, et al. Intraoperative blood transfusion requirement is the main determinant of early surgical re-intervention after orthotopic liver transplantation. Transpl Int. 2005;17(11):673-679.
16. Kaneko J, Sugawara Y, Tamura S, et al. Coagulation and fibrinolytic profiles and appropriate use of heparin after living-donor liver transplantation. Clin Transplant. 2005;19(6):804-809.
17. Gologorsky E, Andrews DM, Gologorsky A, et al. Devastating intracardiac and aortic thrombosis: a case report of apparent catastrophic antiphospholipid syndrome during liver transplantation. J Clin Anesth. 2011;23(5):398-402.
18. Warnaar N, Molenaar IQ, Colquhoun SD, et al. Intraoperative pulmonary embolism and intracardiac thrombosis complicating liver transplantation: a systematic review. J Thromb Haemost. 2008;6(2):297-302.
19. Ellenberger C, Mentha G, Giostra E, Licker M. Cardiovascular collapse due to massive pulmonary thromboembolism during orthotopic liver transplantation. J Clin Anesth. 2006;18(5): 367-371.
20. Gologorsky E, De Wolf AM, Scott V, Aggarwal S, Dishart M, Kang Y. Intracardiac thrombus formation and pulmonary thromboembolism immediately after graft reperfusion in 7 patients undergoing liver transplantation. Liver Transpl. 2001;7(9): 783-789.
21. Jain A, Costa G, Marsh W, et al. Thrombotic and nonthrombotic hepatic artery complications in adults and children following primary liver transplantation with long-term follow-up in 1000 consecutive patients. Transpl Int. 2006;19(1):27-37.
22. Bekker J, Ploem S, de Jong KP. Early hepatic artery thrombosis after liver transplantation: a systematic review of the incidence, outcome and risk factors. Am J Transpl. 2009;9(4):746-757.
23. Nikeghbalian S, Kazemi K, Davari HR, et al. Early hepatic artery thrombosis after liver transplantation: diagnosis and treatment. Transpl Proc. 2007;39(4):1195-1196.
24. Hibi T, Nishida S, Levi DM, et al. Long-term deleterious effects of aortohepatic conduits in primary liver transplantation: proceed with caution. Liver Transpl. 2013;19(8):916-925.
25. Warner P, Fusai G, Glantzounis GK, et al. Risk factors associated with early hepatic artery thrombosis after orthotopic liver transplantation-univariable and multivariable analysis. Transpl Int. 2011;24(4):401-408.
26. You S, He XS, Hu AB, et al. The analysis of portal vein thrombosis following orthotopic liver transplantation [in Chinese]. Zhonghua wai ke za zhi [Chin J Surg]. 2008;46(3):176-178.
27. Singhal A, Karachristos A, Bromberg M, Daly E, Maloo M, Jain AK. Hypercoagulability in end-stage liver disease: prevalence and its correlation with severity of liver disease and portal vein thrombosis. Clin Appl Thromb Hemost. 2012;18(6):594-598.
28. Khalaf H. Vascular complications after deceased and living donor liver transplantation: a single-center experience. Transpl Proc. 2010;42(3):865-870.
29. Sharma R, Kashyap R, Jain A, et al. Surgical complications following liver transplantation in patients with portal vein thrombosis-a single-center perspective. J Gastrointest Surg. 2010;14(3): 520-527.
30. Yerdel MA, Gunson B, Mirza D, et al. Portal vein thrombosis in adults undergoing liver transplantation: risk factors, screening, management, and outcome. Transplantation. 2000;69(9):1873-1881.
31. Ooi CY, Brandao LR, Zolpys L, et al. Thrombotic events after pediatric liver transplantation. Pediatr Transpl. 2010;14(4): 476-482.
32. Varela-Fascinetto G, Hernandez-Plata JA, Nieto-Zermeno J, et al. Pediatric liver transplant program at hospital infantil de mexico federico Gomez [in Spanish]. Rev Invest Clin. 2011;63(suppl 1): 57-61.
33. Shirouzu Y, Kasahara M, Morioka D, et al. Vascular reconstruction and complications in living donor liver transplantation in infants weighing less than 6 kilograms: the Kyoto experience. Liver Transpl. 2006;12(8):1224-1232.
34. Broniszczak D, Szymczak M, Kaminski A, et al. Vascular complications after pediatric liver transplantation from the living donors. Transpl Proc. 2006;38(5):1456-1458.
35. McLin VA, Rimensberger P, Belli DC, Wildhaber BE. Anticoagulation following pediatric liver transplantation reduces early thrombotic events. Pediatr Transpl. 2011;15(1):117-118.
36. Sanchez SE, Javid PJ, Lao OB, et al. Hepatic artery thrombosis and liver malignancy in pediatric liver transplantation. J Pediatr Surg. 2012;47(6):1255-1260.
37. Shay R, Taber D, Pilch N, et al. Early aspirin therapy may reduce hepatic artery thrombosis in liver transplantation. Transpl Proc. 2013;45(1):330-334.
38. Vivarelli M, La Barba G, Cucchetti A, et al. Can antiplatelet prophylaxis reduce the incidence of hepatic artery thrombosis after liver transplantation? Liver Transpl. 2007;13(5):651-654.