Peri-strut low-intensity areas in optical coherence tomography correlate with peri-strut inflammation and neointimal proliferation: An in-vivo correlation study in the familial hypercholesterolemic coronary swine model of in-stent restenosis

Coronary Artery Disease

Volumn 25, Issue 7, 2014, Pages 595-601

  Tellez, Armando ^a   Afari, Maxwell E ^a,b   Buszman, Piotr P ^a   Seifert, Paul ^c   Cheng, Yanping ^a   Milewski, Krzysztof ^a   McGregor, Jennifer C ^a   Garza, Javier A ^a   Roberts, Mary B ^b   Yi, Geng Hua ^a   Kaluza, Greg L ^a   Granada, Juan F ^a  

^a CARDIOVASCULAR RESEARCH FOUNDATION   (United States)

^b BROWN UNIVERSITY   (United States)

^c BOSTON SCIENTIFIC CORPORATION   (United States)

Author keywords

Animal models of disease; Coronary neointimal formation; Familial hypercholesterolemic swine; Optical coherence tomography; Peri strut low intensity area

Indexed keywords

EVEROLIMUS; FIBRIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERY INTIMA PROLIFERATION; ARTICLE; BARE METAL STENT; CORONARY ARTERY OBSTRUCTION; CORONARY BLOOD VESSEL; CORRELATIONAL STUDY; DIAGNOSTIC TEST ACCURACY STUDY; DRUG ELUTING STENT; FAMILIAL HYPERCHOLESTEROLEMIA; FIBRIN DEPOSITION; IN VIVO STUDY; IN-STENT RESTENOSIS; NONHUMAN; OPTICAL COHERENCE TOMOGRAPHY; PERI STRUT LOW INTENSITY AREA; PRIORITY JOURNAL; RADIOLOGICAL PARAMETERS; SENSITIVITY AND SPECIFICITY; TISSUE SECTION; ANIMAL; CORONARY ARTERY DISEASE; DISEASE MODEL; GRAFT OCCLUSION; HYPERPLASIA; INFLAMMATION; MALE; METABOLISM; NEOINTIMA; PATHOLOGY; PIG; RESTENOSIS; STENT;

ANIMALS; CORONARY ARTERY DISEASE; CORONARY RESTENOSIS; CORONARY VESSELS; DISEASE MODELS, ANIMAL; DRUG-ELUTING STENTS; FIBRIN; GRAFT OCCLUSION, VASCULAR; HYPERLIPOPROTEINEMIA TYPE II; HYPERPLASIA; INFLAMMATION; MALE; NEOINTIMA; STENTS; SWINE; TOMOGRAPHY, OPTICAL COHERENCE;

EID: 84927697957     PISSN: 09546928     EISSN: 14735830     Source Type: Journal    
DOI: 10.1097/MCA.0000000000000134     Document Type: Article

References (17)

1. Coletta J, Suzuki N, Nascimento BR, Bezerra HG, Rosenthal N, Guagliumi G, et al. Use of optical coherence tomography for accurate characterization of atherosclerosis. Arq Bras Cardiol 2010;94:250-254.
2. Jang IK, Bouma BE, Kang DH, Park SJ, Park SW, Seung KB, et al. Visualization of coronary atherosclerotic plaques in patients using optical coherence tomography: comparison with intravascular ultrasound. J Am Coll Cardiol 2002;39:604-609.
3. Yamaguchi T, Terashima M, Akasaka T, Hayashi T, Mizuno K, Muramatsu T, et al. Safety and feasibility of an intravascular optical coherence tomography image wire system in the clinical setting. Am J Cardiol 2008;101:562-567.
4. Murata A, Wallace-Bradley D, Tellez A, Alviar C, Aboodi M, Sheehy A, et al. Accuracy of optical coherence tomography in the evaluation of neointimal coverage after stent implantation. JACC Cardiovasc Imaging 2010;3:76-84.
5. Kim JS, Afari ME, Ha J, Tellez A, Milewski K, Conditt G, et al. Neointimal patterns obtained by optical coherence tomography correlate with specific histological components and neointimal proliferation in a swine model of restenosis. Eur Heart J Cardiovasc Imaging 2014;15:292-298.
6. Teramoto T, Ikeno F, Otake H, Lyons JK, Van Beusekom HM, Fearon WF, Yeung AC. Intriguing peri-strut low-intensity area detected by optical coherence tomography after coronary stent deployment. Circ J 2010;74:1257-1259.
7. Hasler-Rapacz J, Ellegren H, Fridolfsson AK, Kirkpatrick B, Kirk S, Andersson L, Rapacz J. Identification of a mutation in the low density lipoprotein receptor gene associated with recessive familial hypercholesterolemia in swine. Am J Med Genet 1998;76:379-386.
8. Prescott MF, McBride CH, Hasler-Rapacz J, Von Linden J, Rapacz J. Development of complex atherosclerotic lesions in pigs with inherited hyper-LDL cholesterolemia bearing mutant alleles for apolipoprotein B. Am J Pathol 1991;139:139-147.
9. Tellez A, Krueger CG, Seifert P, Winsor-Hines D, Piedrahita C, Cheng Y, et al. Coronary bare metal stent implantation in homozygous LDL receptor deficient swine induces a neointimal formation pattern similar to humans. Atherosclerosis 2010;213:518-524.
10. Bezerra HG, Costa MA, Guagliumi G, Rollins AM, Simon DI. Intracoronary optical coherence tomography: a comprehensive review clinical and research applications. JACC Cardiovasc Interv 2009;2:1035-1046.
11. Otake H, Shite J, Ikeno F, Shinke T, Teramoto T, Miyoshi N, et al. Evaluation of the peri-strut low intensity area following sirolimus- and paclitaxel-eluting stents implantation: insights from an optical coherence tomography study in humans. Int J Cardiol 2012;157:38-42.
12. Finn AV, Kolodgie FD, Harnek J, Guerrero LJ, Acampado E, Tefera K, et al. Differential response of delayed healing and persistent inflammation at sites of overlapping sirolimus- or paclitaxel-eluting stents. Circulation 2005;112:270-278.
13. Li JJ. Inflammatory response, drug-eluting stent and restenosis. Chin Med J (Engl) 2008;121:566-572.
14. Nakano M, Vorpahl M, Otsuka F, Taniwaki M, Yazdani SK, Finn AV, et al. Ex vivo assessment of vascular response to coronary stents by optical frequency domain imaging. JACC Cardiovasc Imaging 2012;5:71-82.
15. Kornowski R, Hong MK, Tio FO, Bramwell O, Wu H, Leon MB. In-stent restenosis: contributions of inflammatory responses and arterial injury to neointimal hyperplasia. J Am Coll Cardiol 1998;31:224-230.
16. Inoue T, Shite J, Yoon J, Shinke T, Otake H, Sawada T, et al. Optical coherence evaluation of everolimus-eluting stents 8 months after implantation. Heart 2011;97:1379-1384.
17. Gonzalo N, Serruys PW, Okamura T, Shen ZJ, Onuma Y, Garcia-Garcia HM, et al. Optical coherence tomography assessment of the acute effects of stent implantation on the vessel wall: a systematic quantitative approach. Heart 2009;95:1913-1919.